{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,12]],"date-time":"2026-10-12T14:20:43Z","timestamp":1791814843215,"version":"4.3.4"},"reference-count":82,"publisher":"Springer Science and Business Media LLC","issue":"2","license":[{"start":{"date-parts":[[2021,8,13]],"date-time":"2021-08-13T00:00:00Z","timestamp":1628812800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springer.com\/tdm"},{"start":{"date-parts":[[2021,8,13]],"date-time":"2021-08-13T00:00:00Z","timestamp":1628812800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Clin Oral Invest"],"published-print":{"date-parts":[[2022,2]]},"DOI":"10.1007\/s00784-021-04123-z","type":"journal-article","created":{"date-parts":[[2021,8,13]],"date-time":"2021-08-13T07:02:51Z","timestamp":1628838171000},"page":"1505-1516","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":16,"title":["Management of internal inflammatory root resorption using injectable platelet-rich fibrin revascularization technique: a clinical study with cone-beam computed tomography evaluation"],"prefix":"10.1007","volume":"26","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-0592-6956","authenticated-orcid":false,"given":"Mohamed","family":"Nageh","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lamiaa A.","family":"Ibrahim","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fatma M.","family":"AbuNaeem","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Engy","family":"Salam","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2021,8,13]]},"reference":[{"key":"4123_CR1","first-page":"9","volume":"30","author":"RF Ne","year":"1999","unstructured":"Ne RF, Witherspoon DE, Gutmann JL (1999) Tooth resorption Quintessence Int (Berl) 30:9\u201325","journal-title":"Tooth resorption Quintessence Int (Berl)"},{"key":"4123_CR2","doi-asserted-by":"publisher","first-page":"1101","DOI":"10.1007\/s00784-020-03199-3","volume":"24","author":"BDM de Souza","year":"2020","unstructured":"de Souza BDM, Dutra KL, Reyes-Carmona J et al (2020) Incidence of root resorption after concussion, subluxation, lateral luxation, intrusion, and extrusion: a systematic review. Clin Oral Investig 24:1101\u20131111. https:\/\/doi.org\/10.1007\/s00784-020-03199-3","journal-title":"Clin Oral Investig"},{"key":"4123_CR3","doi-asserted-by":"publisher","first-page":"60","DOI":"10.1111\/j.1601-1546.2008.00226.x","volume":"14","author":"M Haapasalo","year":"2006","unstructured":"Haapasalo M, Endal U (2006) Internal inflammatory root resorption: the unknown resorption of the tooth. Endod Top 14:60\u201379. https:\/\/doi.org\/10.1111\/j.1601-1546.2008.00226.x","journal-title":"Endod Top"},{"key":"4123_CR4","doi-asserted-by":"publisher","first-page":"1121","DOI":"10.1016\/j.joen.2007.06.011","volume":"33","author":"TP Cotton","year":"2007","unstructured":"Cotton TP, Geisler TM, Holden DT, Schwartz SA (2007) Endodontic applications of cone-beam volumetric tomography. J Endod 33:1121\u20131132. https:\/\/doi.org\/10.1016\/j.joen.2007.06.011","journal-title":"J Endod"},{"key":"4123_CR5","doi-asserted-by":"publisher","first-page":"548","DOI":"10.1016\/j.joen.2012.11.038","volume":"39","author":"RL Ball","year":"2013","unstructured":"Ball RL, Barbizam JV, Cohenca N (2013) Intraoperative endodontic applications of cone-beam computed tomography. J Endod 39:548\u2013557. https:\/\/doi.org\/10.1016\/j.joen.2012.11.038","journal-title":"J Endod"},{"key":"4123_CR6","doi-asserted-by":"publisher","first-page":"1491","DOI":"10.1016\/j.joen.2009.08.009","volume":"35","author":"C Estrela","year":"2009","unstructured":"Estrela C, Bueno MR, De Alencar AHG et al (2009) Method to evaluate inflammatory root resorption by using cone beam computed tomography. J Endod 35:1491\u20131497. https:\/\/doi.org\/10.1016\/j.joen.2009.08.009","journal-title":"J Endod"},{"key":"4123_CR7","doi-asserted-by":"publisher","unstructured":"Jain H, Vasudev N (2018) Comparison between the use of thermoplasticized gutta- percha and a polydimethyl siloxane-based material in filling internal resorptive cavities using spiral computed tomography. Microsc Res Tech 1\u20134. https:\/\/doi.org\/10.1002\/jemt.23163","DOI":"10.1002\/jemt.23163"},{"key":"4123_CR8","doi-asserted-by":"publisher","first-page":"784","DOI":"10.1016\/j.tripleo.2010.07.008","volume":"110","author":"M Brito-J\u00fanior","year":"2010","unstructured":"Brito-J\u00fanior M, Quintino AFC, Camilo CC et al (2010) Nonsurgical endodontic management using MTA for perforative defect of internal root resorption: report of a long term follow-up. Oral Surg, Oral Med Oral Pathol Oral Radiol Endodontol 110:784\u2013788. https:\/\/doi.org\/10.1016\/j.tripleo.2010.07.008","journal-title":"Oral Surg, Oral Med Oral Pathol Oral Radiol Endodontol"},{"key":"4123_CR9","doi-asserted-by":"publisher","first-page":"777","DOI":"10.1111\/j.1365-2591.2011.01870.x","volume":"44","author":"B Bhuva","year":"2011","unstructured":"Bhuva B, Barnes JJ, Patel S (2011) The use of limited cone beam computed tomography in the diagnosis and management of a case of perforating internal root resorption. Int Endod J 44:777\u2013786. https:\/\/doi.org\/10.1111\/j.1365-2591.2011.01870.x","journal-title":"Int Endod J"},{"key":"4123_CR10","first-page":"47","volume":"29","author":"B Thibodeau","year":"2007","unstructured":"Thibodeau B, Trope M (2007) Pulp revascularization of a necrotic infected immature permanent tooth: case report and review of the literature. Pediatr Dent 29:47\u201350","journal-title":"Pediatr Dent"},{"key":"4123_CR11","doi-asserted-by":"publisher","first-page":"313","DOI":"10.1016\/j.cden.2009.12.006","volume":"54","author":"M Trope","year":"2010","unstructured":"Trope M (2010) Treatment of the immature tooth with a non-vital pulp and apical periodontitis. Dent Clin North Am 54:313\u2013324. https:\/\/doi.org\/10.1016\/j.cden.2009.12.006","journal-title":"Dent Clin North Am"},{"key":"4123_CR12","doi-asserted-by":"publisher","first-page":"395","DOI":"10.4103\/0972-0707.101926","volume":"15","author":"VY Shivashankar","year":"2012","unstructured":"Shivashankar VY, Johns DA, Vidyanath S, Kumar MR (2012) Platelet rich fibrin in the revitalization of tooth with necrotic pulp and open apex. J Conserv Dent 15:395\u2013398. https:\/\/doi.org\/10.4103\/0972-0707.101926","journal-title":"J Conserv Dent"},{"key":"4123_CR13","doi-asserted-by":"publisher","first-page":"265","DOI":"10.1016\/j.joen.2010.11.004","volume":"37","author":"M Torabinejad","year":"2011","unstructured":"Torabinejad M, Turman M (2011) Revitalization of tooth with necrotic pulp and open apex by using platelet-rich plasma: a case report. J Endod 37:265\u2013268. https:\/\/doi.org\/10.1016\/j.joen.2010.11.004","journal-title":"J Endod"},{"key":"4123_CR14","doi-asserted-by":"publisher","first-page":"1096","DOI":"10.1111\/iej.12107","volume":"46","author":"D Keswani","year":"2013","unstructured":"Keswani D, Pandey RK (2013) Revascularization of an immature tooth with a necrotic pulp using platelet-rich fibrin: a case report. Int Endod J 46:1096\u20131104. https:\/\/doi.org\/10.1111\/iej.12107","journal-title":"Int Endod J"},{"key":"4123_CR15","doi-asserted-by":"publisher","first-page":"328","DOI":"10.4103\/0972-0707.101889","volume":"15","author":"N Shah","year":"2012","unstructured":"Shah N, Logani A (2012) SealBio: a novel, non-obturation endodontic treatment based on concept of regeneration. J Conserv Dent 15:328\u2013332. https:\/\/doi.org\/10.4103\/0972-0707.101889","journal-title":"J Conserv Dent"},{"key":"4123_CR16","doi-asserted-by":"publisher","first-page":"929","DOI":"10.1016\/j.joen.2013.04.029","volume":"39","author":"K Paryani","year":"2013","unstructured":"Paryani K, Kim SG (2013) Regenerative endodontic treatment of permanent teeth after completion of root development: a report of 2 cases. J Endod 39:929\u2013934. https:\/\/doi.org\/10.1016\/j.joen.2013.04.029","journal-title":"J Endod"},{"key":"4123_CR17","doi-asserted-by":"publisher","first-page":"57","DOI":"10.1016\/j.joen.2015.09.015","volume":"42","author":"TM Saoud","year":"2016","unstructured":"Saoud TM, Martin G, Chen Y-HM et al (2016) Treatment of mature permanent teeth with necrotic pulps and apical periodontitis using regenerative endodontic procedures: a case series. J Endod 42:57\u201365. https:\/\/doi.org\/10.1016\/j.joen.2015.09.015","journal-title":"J Endod"},{"key":"4123_CR18","doi-asserted-by":"publisher","first-page":"1526","DOI":"10.1016\/j.joen.2018.06.014","volume":"44","author":"M Nageh","year":"2018","unstructured":"Nageh M, Ahmed GM, El-Baz AA (2018) Assessment of regaining pulp sensibility in mature necrotic teeth using a modified revascularization technique with platelet-rich fibrin: a clinical study. J Endod 44:1526\u20131533. https:\/\/doi.org\/10.1016\/j.joen.2018.06.014","journal-title":"J Endod"},{"key":"4123_CR19","doi-asserted-by":"publisher","first-page":"1560","DOI":"10.1016\/j.joen.2015.03.019","volume":"41","author":"CN Santiago","year":"2015","unstructured":"Santiago CN, Pinto SS, Sassone LM et al (2015) Revascularization technique for the treatment of external inflammatory root resorption\u202f: a report of 3 cases. J Endod 41:1560\u20131564. https:\/\/doi.org\/10.1016\/j.joen.2015.03.019","journal-title":"J Endod"},{"key":"4123_CR20","unstructured":"AAE-American Association of Endodontics (2016) Regenerative endodontics"},{"key":"4123_CR21","doi-asserted-by":"publisher","first-page":"2619","DOI":"10.1007\/s00784-017-2063-9","volume":"21","author":"RJ Miron","year":"2017","unstructured":"Miron RJ, Fujioka-kobayashi M, Hernandez M (2017) Injectable platelet rich fibrin ( i-PRF ): opportunities in regenerative dentistry\u202f? Clin Oral Investig 21:2619\u20132627. https:\/\/doi.org\/10.1007\/s00784-017-2063-9","journal-title":"Clin Oral Investig"},{"key":"4123_CR22","doi-asserted-by":"publisher","unstructured":"Dohan DM, Choukroun J, Diss A, et al (2006) Platelet-rich fibrin (PRF): a second-generation platelet concentrate. Part I: Technological concepts and evolution. Oral Surgery, Oral Med Oral Pathol Oral Radiol Endodontology 101:. https:\/\/doi.org\/10.1016\/j.tripleo.2005.07.008","DOI":"10.1016\/j.tripleo.2005.07.008"},{"key":"4123_CR23","doi-asserted-by":"publisher","first-page":"20170325","DOI":"10.1259\/dmfr.20170325","volume":"47","author":"G S\u00f6nmez","year":"2018","unstructured":"S\u00f6nmez G, Ko\u00e7 C, Kamburo\u011flu K (2018) Accuracy of linear and volumetric measurements of artificial ERR cavities by using CBCT images obtained at 4 different voxel sizes and measured by using 4 different software: an ex vivo research. Dentomaxillofac Radiol 47:20170325. https:\/\/doi.org\/10.1259\/dmfr.20170325","journal-title":"Dentomaxillofac Radiol"},{"key":"4123_CR24","doi-asserted-by":"crossref","unstructured":"Faul F, Erdfelder E, Lang AG, Buchner A (2007) G*Power 3: a flexible statistical power analysis program for the social, behavioral, and biomedical sciences. In: Behavior Research Methods. Psychonomic Society Inc., pp 175\u2013191","DOI":"10.3758\/BF03193146"},{"key":"4123_CR25","doi-asserted-by":"publisher","first-page":"483","DOI":"10.1002\/jemt.10370","volume":"61","author":"T Sasaki","year":"2003","unstructured":"Sasaki T (2003) Differentiation and functions of osteoclasts and odontoclasts in mineralized tissue resorption. Microsc Res Tech 61:483\u2013495. https:\/\/doi.org\/10.1002\/jemt.10370","journal-title":"Microsc Res Tech"},{"key":"4123_CR26","doi-asserted-by":"publisher","first-page":"367","DOI":"10.2334\/josnusd.50.367","volume":"50","author":"JB Tyrovola","year":"2008","unstructured":"Tyrovola JB, Spyropoulos MN, Makou M, Perrea D (2008) Root resorption and the OPG\/RANKL\/RANK system: a mini review. J Oral Sci 50:367\u2013376. https:\/\/doi.org\/10.2334\/josnusd.50.367","journal-title":"J Oral Sci"},{"key":"4123_CR27","doi-asserted-by":"publisher","first-page":"929486","DOI":"10.1155\/2013\/929486","volume":"2013","author":"E Nilsson","year":"2013","unstructured":"Nilsson E, Bonte E, Bayet F, Lasfargues J-J (2013) Management of internal root resorption on permanent teeth. Int J Dent 2013:929486. https:\/\/doi.org\/10.1155\/2013\/929486","journal-title":"Int J Dent"},{"key":"4123_CR28","doi-asserted-by":"publisher","first-page":"411","DOI":"10.1016\/j.joen.2010.11.015","volume":"37","author":"S Asgary","year":"2011","unstructured":"Asgary S, Nosrat A, Seifi A (2011) Management of inflammatory external root resorption by using calcium-enriched mixture cement\u202f: a case report. J Endod 37:411\u2013413. https:\/\/doi.org\/10.1016\/j.joen.2010.11.015","journal-title":"J Endod"},{"key":"4123_CR29","doi-asserted-by":"publisher","first-page":"245","DOI":"10.1016\/j.joen.2017.11.006","volume":"44","author":"GN Tzanetakis","year":"2018","unstructured":"Tzanetakis GN (2018) Management of intruded immature maxillary central incisor with pulp necrosis and severe external resorption by regenerative approach. J Endod 44:245\u2013249. https:\/\/doi.org\/10.1016\/j.joen.2017.11.006","journal-title":"J Endod"},{"key":"4123_CR30","doi-asserted-by":"publisher","first-page":"120","DOI":"10.1046\/j.1365-2591.2001.00357.x","volume":"34","author":"TPC Sim","year":"2001","unstructured":"Sim TPC, Knowles JC, Ng YL et al (2001) Effect of sodium hypochlorite on mechanical properties of dentine and tooth surface strain. Int Endod J 34:120\u2013132. https:\/\/doi.org\/10.1046\/j.1365-2591.2001.00357.x","journal-title":"Int Endod J"},{"key":"4123_CR31","doi-asserted-by":"publisher","first-page":"1109","DOI":"10.1016\/j.joen.2011.05.013","volume":"37","author":"EG Trevino","year":"2011","unstructured":"Trevino EG, Patwardhan AN, Henry MA et al (2011) Effect of irrigants on the survival of human stem cells of the apical papilla in a platelet-rich plasma scaffold in human root tips. J Endod 37:1109\u20131115. https:\/\/doi.org\/10.1016\/j.joen.2011.05.013","journal-title":"J Endod"},{"key":"4123_CR32","doi-asserted-by":"publisher","first-page":"697","DOI":"10.1111\/J.1365-2591.2011.01886.X","volume":"44","author":"Z Mohammadi","year":"2011","unstructured":"Mohammadi Z, Dummer P (2011) Properties and applications of calcium hydroxide in endodontics and dental traumatology. Int Endod J 44:697\u2013730. https:\/\/doi.org\/10.1111\/J.1365-2591.2011.01886.X","journal-title":"Int Endod J"},{"key":"4123_CR33","doi-asserted-by":"publisher","first-page":"104","DOI":"10.1111\/j.1600-9657.1992.tb00445.x","volume":"8","author":"M Andersen","year":"1992","unstructured":"Andersen M, Lund A, Andreasen JO, Andreasen FM (1992) In vitro solubility of human pulp tissue in calcium hydroxide and sodium hypochlorite. Dent Traumatol 8:104\u2013108. https:\/\/doi.org\/10.1111\/j.1600-9657.1992.tb00445.x","journal-title":"Dent Traumatol"},{"key":"4123_CR34","doi-asserted-by":"publisher","first-page":"89","DOI":"10.1016\/j.joen.2015.08.021","volume":"42","author":"P Kitikuson","year":"2016","unstructured":"Kitikuson P, Srisuwan T (2016) Attachment ability of human apical papilla cells to root dentin surfaces treated with either 3mix or calcium hydroxide. J Endod 42:89\u201394. https:\/\/doi.org\/10.1016\/j.joen.2015.08.021","journal-title":"J Endod"},{"key":"4123_CR35","doi-asserted-by":"publisher","first-page":"1172","DOI":"10.1016\/j.joen.2013.12.027","volume":"40","author":"JA Berkhoff","year":"2014","unstructured":"Berkhoff JA, Chen PB, Teixeira FB, Diogenes A (2014) Evaluation of triple antibiotic paste removal by different irrigation procedures. J Endod 40:1172\u20131177. https:\/\/doi.org\/10.1016\/j.joen.2013.12.027","journal-title":"J Endod"},{"key":"4123_CR36","doi-asserted-by":"publisher","first-page":"636","DOI":"10.1016\/j.jdent.2007.04.008","volume":"35","author":"PL Tomson","year":"2007","unstructured":"Tomson PL, Grover LM, Lumley PJ et al (2007) Dissolution of bio-active dentine matrix components by mineral trioxide aggregate. J Dent 35:636\u2013642. https:\/\/doi.org\/10.1016\/j.jdent.2007.04.008","journal-title":"J Dent"},{"key":"4123_CR37","doi-asserted-by":"publisher","first-page":"611","DOI":"10.1038\/sj.gt.3302687","volume":"13","author":"A Almushayt","year":"2006","unstructured":"Almushayt A, Narayanan K, Zaki AE, George A (2006) Dentin matrix protein 1 induces cytodifferentiation of dental pulp stem cells into odontoblasts. Gene Ther 13:611\u2013620. https:\/\/doi.org\/10.1038\/sj.gt.3302687","journal-title":"Gene Ther"},{"key":"4123_CR38","doi-asserted-by":"publisher","first-page":"3023","DOI":"10.1089\/ten.tea.2010.0181","volume":"16","author":"JY Kim","year":"2010","unstructured":"Kim JY, Xin X, Moioli EK et al (2010) Regeneration of dental-pulp-like tissue by chemotaxis-induced cell homing. Tissue Eng Part A 16:3023\u20133031. https:\/\/doi.org\/10.1089\/ten.tea.2010.0181","journal-title":"Tissue Eng Part A"},{"key":"4123_CR39","doi-asserted-by":"publisher","first-page":"S30","DOI":"10.1016\/j.joen.2012.11.025","volume":"39","author":"KM Hargreaves","year":"2013","unstructured":"Hargreaves KM, Diogenes A, Teixeira FB (2013) Treatment options\u202f: biological basis of regenerative endodontic procedures. J Endod 39:S30\u2013S43. https:\/\/doi.org\/10.1016\/j.joen.2012.11.025","journal-title":"J Endod"},{"key":"4123_CR40","doi-asserted-by":"publisher","first-page":"204","DOI":"10.1016\/S0022-3913(03)00338-X","volume":"90","author":"AR S\u00e1nchez","year":"2003","unstructured":"S\u00e1nchez AR, Sheridan PJKL (2003) Is platelet-rich plasma the perfect enhancement factor? A Curr Review J Prosthet Dent 90:204. https:\/\/doi.org\/10.1016\/S0022-3913(03)00338-X","journal-title":"A Curr Review J Prosthet Dent"},{"key":"4123_CR41","doi-asserted-by":"publisher","first-page":"4551","DOI":"10.1016\/j.biomaterials.2007.06.037","volume":"28","author":"E Anitua","year":"2007","unstructured":"Anitua E, S\u00e1nchez M, Orive G, And\u00eda I (2007) The potential impact of the preparation rich in growth factors (PRGF) in different medical fields\u2606. Biomaterials 28:4551\u20134560. https:\/\/doi.org\/10.1016\/j.biomaterials.2007.06.037","journal-title":"Biomaterials"},{"key":"4123_CR42","doi-asserted-by":"publisher","first-page":"546","DOI":"10.1902\/jop.2009.090531","volume":"81","author":"DM Dohan Ehrenfest","year":"2010","unstructured":"Dohan Ehrenfest DM, Del Corso M, Diss A et al (2010) Three-dimensional architecture and cell composition of a Choukroun\u2019s platelet-rich fibrin clot and membrane. J Periodontol 81:546\u2013555. https:\/\/doi.org\/10.1902\/jop.2009.090531","journal-title":"J Periodontol"},{"key":"4123_CR43","doi-asserted-by":"publisher","first-page":"284","DOI":"10.4103\/0972-0707.114344","volume":"16","author":"B Naik","year":"2013","unstructured":"Naik B, Karunakar P, Jayadev M, Marshal VR (2013) Role of platelet rich fibrin in wound healing: a critical review. J Conserv Dent 16:284\u2013293. https:\/\/doi.org\/10.4103\/0972-0707.114344","journal-title":"J Conserv Dent"},{"key":"4123_CR44","doi-asserted-by":"publisher","first-page":"e37","DOI":"10.1016\/j.tripleo.2005.07.008","volume":"101","author":"DM Dohan","year":"2006","unstructured":"Dohan DM, Choukroun J, Diss A et al (2006) Platelet-rich fibrin (PRF): a second-generation platelet concentrate. Part I: Technological concepts and evolution. Oral Surg, Oral Med Oral Pathol Oral Radiol Endodontol 101:e37\u2013e44. https:\/\/doi.org\/10.1016\/j.tripleo.2005.07.008","journal-title":"Oral Surg, Oral Med Oral Pathol Oral Radiol Endodontol"},{"key":"4123_CR45","doi-asserted-by":"publisher","first-page":"63","DOI":"10.1080\/08977190802636713","volume":"27","author":"DM Dohan Ehrenfest","year":"2009","unstructured":"Dohan Ehrenfest DM, de Peppo GM, Doglioli P, Sammartino G (2009) Slow release of growth factors and thrombospondin-1 in Choukroun\u2019s platelet-rich fibrin (PRF): a gold standard to achieve for all surgical platelet concentrates technologies. Growth Factors 27:63\u201369. https:\/\/doi.org\/10.1080\/08977190802636713","journal-title":"Growth Factors"},{"key":"4123_CR46","first-page":"3","volume":"1","author":"J Choukroun","year":"2014","unstructured":"Choukroun J (2014) Advanced PRF & i-PRF: platelet concentrates or blood concentrates. J Periodontal Med Clin Pract 1:3","journal-title":"J Periodontal Med Clin Pract"},{"key":"4123_CR47","doi-asserted-by":"publisher","first-page":"87","DOI":"10.1007\/s00068-017-0767-9","volume":"44","author":"J Choukroun","year":"2018","unstructured":"Choukroun J, Ghanaati S (2018) Reduction of relative centrifugation force within injectable platelet-rich-fibrin (PRF) concentrates advances patients\u2019 own inflammatory cells, platelets and growth factors: the first introduction to the low speed centrifugation concept. Eur J Trauma Emerg Surg 44:87\u201395. https:\/\/doi.org\/10.1007\/s00068-017-0767-9","journal-title":"Eur J Trauma Emerg Surg"},{"key":"4123_CR48","doi-asserted-by":"publisher","first-page":"97","DOI":"10.4103\/jisp.jisp_201_17","volume":"21","author":"PA Karde","year":"2017","unstructured":"Karde PA, Sethi KS, Mahale SA et al (2017) Comparative evaluation of platelet count and antimicrobial efficacy of injectable platelet-rich fibrin with other platelet concentrates: an in vitro study. J Indian Soc Periodontol 21:97\u2013101. https:\/\/doi.org\/10.4103\/jisp.jisp_201_17","journal-title":"J Indian Soc Periodontol"},{"key":"4123_CR49","doi-asserted-by":"publisher","first-page":"314","DOI":"10.1038\/nature07039","volume":"453","author":"GC Gurtner","year":"2008","unstructured":"Gurtner GC, Werner S, Barrandon Y, Longaker MT (2008) Wound repair and regeneration. Nature 453:314\u2013321. https:\/\/doi.org\/10.1038\/nature07039","journal-title":"Nature"},{"key":"4123_CR50","doi-asserted-by":"publisher","first-page":"2257","DOI":"10.1002\/jbm.a.36734","volume":"107","author":"RJ Miron","year":"2019","unstructured":"Miron RJ, Chai J, Zheng S et al (2019) A novel method for evaluating and quantifying cell types in platelet rich fibrin and an introduction to horizontal centrifugation. J Biomed Mater Res - Part A 107:2257\u20132271. https:\/\/doi.org\/10.1002\/jbm.a.36734","journal-title":"J Biomed Mater Res - Part A"},{"key":"4123_CR51","doi-asserted-by":"publisher","unstructured":"Fern\u00e1ndez-Medina T, Vaquette C, Ivanovski S (2019) Systematic comparison of the effect of four clinical-grade platelet rich hemoderivatives on osteoblast behaviour. Int J Mol Sci 20:. https:\/\/doi.org\/10.3390\/ijms20246243","DOI":"10.3390\/ijms20246243"},{"key":"4123_CR52","doi-asserted-by":"publisher","first-page":"77","DOI":"10.1016\/j.ajodo.2012.08.023","volume":"143","author":"SN Ponder","year":"2013","unstructured":"Ponder SN, Benavides E, Kapila S, Hatch NE (2013) Quantification of external root resorption by low- vs high-resolution cone-beam computed tomography and periapical radiography: a volumetric and linear analysis. Am J Orthod Dentofac Orthop Off Publ Am Assoc Orthod its Const Soc Am Board Orthod 143:77\u201391. https:\/\/doi.org\/10.1016\/j.ajodo.2012.08.023","journal-title":"Am J Orthod Dentofac Orthop Off Publ Am Assoc Orthod its Const Soc Am Board Orthod"},{"key":"4123_CR53","doi-asserted-by":"publisher","first-page":"959","DOI":"10.1111\/iej.12390","volume":"48","author":"PF Da Silveira","year":"2015","unstructured":"Da Silveira PF, Fontana MP, Oliveira HW et al (2015) CBCT-based volume of simulated root resorption - influence of FOV and voxel size. Int Endod J 48:959\u2013965. https:\/\/doi.org\/10.1111\/iej.12390","journal-title":"Int Endod J"},{"key":"4123_CR54","doi-asserted-by":"publisher","first-page":"206","DOI":"10.1111\/j.1601-6343.2011.01525.x","volume":"14","author":"Y Wang","year":"2011","unstructured":"Wang Y, He S, Yu L et al (2011) Accuracy of volumetric measurement of teeth in vivo based on cone beam computer tomography. Orthod Craniofac Res 14:206\u2013212. https:\/\/doi.org\/10.1111\/j.1601-6343.2011.01525.x","journal-title":"Orthod Craniofac Res"},{"key":"4123_CR55","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1186\/s41121-020-00020-4","volume":"5","author":"AB Khanna","year":"2020","unstructured":"Khanna AB (2020) Applications of cone beam computed tomography in endodontics. Evidence-Based Endod 5:1. https:\/\/doi.org\/10.1186\/s41121-020-00020-4","journal-title":"Evidence-Based Endod"},{"key":"4123_CR56","doi-asserted-by":"publisher","first-page":"831","DOI":"10.1111\/j.1365-2591.2009.01592.x","volume":"42","author":"S Patel","year":"2009","unstructured":"Patel S, Dawood A, Wilson R et al (2009) The detection and management of root resorption lesions using intraoral radiography and cone beam computed tomography - an in vivo investigation. Int Endod J 42:831\u2013838. https:\/\/doi.org\/10.1111\/j.1365-2591.2009.01592.x","journal-title":"Int Endod J"},{"key":"4123_CR57","doi-asserted-by":"publisher","first-page":"20170325","DOI":"10.1259\/dmfr.20170325","volume":"47","author":"G S\u00f6nmez","year":"2018","unstructured":"S\u00f6nmez G, Ko\u00e7 C, Kamburo\u011flu K (2018) Accuracy of linear and volumetric measurements of artificial ERR cavities by using CBCT images obtained at 4 different voxel sizes and measured by using 4 different software: an ex vivo research. Dentomaxillofacial Radiol 47:20170325. https:\/\/doi.org\/10.1259\/dmfr.20170325","journal-title":"Dentomaxillofacial Radiol"},{"key":"4123_CR58","doi-asserted-by":"publisher","first-page":"211","DOI":"10.22037\/IEJ.V14I3.25005","volume":"14","author":"E Mahmoudi","year":"2019","unstructured":"Mahmoudi E, Madani Z, Moudi E et al (2019) Diagnostic accuracy of high resolution cone-beam computed tomography and standard mode cone-beam computed tomography in internal root resorption. Iran Endod J 14:211\u2013215. https:\/\/doi.org\/10.22037\/IEJ.V14I3.25005","journal-title":"Iran Endod J"},{"key":"4123_CR59","doi-asserted-by":"publisher","first-page":"28","DOI":"10.1259\/DMFR\/31342245","volume":"34","author":"R Marmulla","year":"2005","unstructured":"Marmulla R, Wortche R, Muhling JHS (2005) Geometric accuracy of the NewTom 9000 Cone Beam CT. Dentomaxillofac Radiol 34:28\u201331. https:\/\/doi.org\/10.1259\/DMFR\/31342245","journal-title":"Dentomaxillofac Radiol"},{"key":"4123_CR60","doi-asserted-by":"publisher","first-page":"639","DOI":"10.1016\/j.bjoms.2008.03.019","volume":"46","author":"G Eggers","year":"2008","unstructured":"Eggers G, Klein J, Welzel T, M\u00fchling J (2008) Geometric accuracy of digital volume tomography and conventional computed tomography. Br J Oral Maxillofac Surg 46:639\u2013644. https:\/\/doi.org\/10.1016\/j.bjoms.2008.03.019","journal-title":"Br J Oral Maxillofac Surg"},{"key":"4123_CR61","doi-asserted-by":"publisher","first-page":"291","DOI":"10.1097\/01.rli.0000258663.13199.bf","volume":"42","author":"S Obenauer","year":"2007","unstructured":"Obenauer S, Dullin C, Heuser M (2007) Flat panel detector-based volumetric computed tomography (fpVCT). Invest Radiol 42:291\u2013296. https:\/\/doi.org\/10.1097\/01.rli.0000258663.13199.bf","journal-title":"Invest Radiol"},{"key":"4123_CR62","doi-asserted-by":"publisher","first-page":"410","DOI":"10.1259\/dmfr\/20987648","volume":"35","author":"H Pinsky","year":"2006","unstructured":"Pinsky H, Dyda S, Pinsky R et al (2006) Accuracy of three-dimensional measurements using cone-beam CT. Dentomaxillofacial Radiol 35:410\u2013416. https:\/\/doi.org\/10.1259\/dmfr\/20987648","journal-title":"Dentomaxillofacial Radiol"},{"key":"4123_CR63","doi-asserted-by":"publisher","first-page":"150","DOI":"10.1111\/j.1365-2591.1996.tb01361.x","volume":"29","author":"D \u00d8rstavik","year":"1996","unstructured":"\u00d8rstavik D (1996) Time-course and risk analyses of the development and healing of chronic apical periodontitis in man. Int Endod J 29:150\u2013155. https:\/\/doi.org\/10.1111\/j.1365-2591.1996.tb01361.x","journal-title":"Int Endod J"},{"key":"4123_CR64","doi-asserted-by":"crossref","unstructured":"(2006) Quality guidelines for endodontic treatment: consensus report of the European Society of Endodontology. Int. Endod. J. 39:921\u2013930","DOI":"10.1111\/j.1365-2591.2006.01180.x"},{"key":"4123_CR65","doi-asserted-by":"publisher","first-page":"139","DOI":"10.3389\/fbioe.2018.00139","volume":"6","author":"PE Murray","year":"2018","unstructured":"Murray PE (2018) Platelet-rich plasma and platelet-rich fibrin can induce apical closure more frequently than blood-clot revascularization for the regeneration of immature permanent teeth: a meta-analysis of clinical efficacy. Front Bioeng Biotechnol 6:139. https:\/\/doi.org\/10.3389\/fbioe.2018.00139","journal-title":"Front Bioeng Biotechnol"},{"key":"4123_CR66","doi-asserted-by":"publisher","unstructured":"AAE Clinical Considerations for a Regenerative Procedure Revised 4\/1\/2018. AAE 2018. https:\/\/doi.org\/10.2334\/josnusd.57.213","DOI":"10.2334\/josnusd.57.213"},{"key":"4123_CR67","doi-asserted-by":"publisher","first-page":"S65","DOI":"10.1016\/j.joen.2014.01.023","volume":"40","author":"KM Hargreaves","year":"2014","unstructured":"Hargreaves KM, Diogenes A, Teixeira FB (2014) Paradigm lost: a perspective on the design and interpretation of regenerative endodontic research. J Endod 40:S65\u2013S69. https:\/\/doi.org\/10.1016\/j.joen.2014.01.023","journal-title":"J Endod"},{"key":"4123_CR68","doi-asserted-by":"publisher","first-page":"1476","DOI":"10.1016\/j.joen.2016.04.028","volume":"42","author":"TMA Saoud","year":"2016","unstructured":"Saoud TMA, Mistry S, Kahler B et al (2016) Regenerative endodontic procedures for traumatized teeth after horizontal root fracture, avulsion, and perforating root resorption. J Endod 42:1476\u20131482. https:\/\/doi.org\/10.1016\/j.joen.2016.04.028","journal-title":"J Endod"},{"key":"4123_CR69","doi-asserted-by":"publisher","first-page":"128","DOI":"10.1111\/iej.12784","volume":"51","author":"ME Kaval","year":"2018","unstructured":"Kaval ME, G\u00fcneri P, \u00c7al\u0131\u015fkan MK (2018) Regenerative endodontic treatment of perforated internal root resorption: a case report. Int Endod J 51:128\u2013137. https:\/\/doi.org\/10.1111\/iej.12784","journal-title":"Int Endod J"},{"key":"4123_CR70","doi-asserted-by":"publisher","first-page":"317","DOI":"10.1016\/j.joen.2014.10.023","volume":"41","author":"M Ezeldeen","year":"2015","unstructured":"Ezeldeen M, Mscd DDS, Van GG et al (2015) 3-dimensional analysis of regenerative endodontic. J Endod 41:317\u2013324. https:\/\/doi.org\/10.1016\/j.joen.2014.10.023","journal-title":"J Endod"},{"key":"4123_CR71","doi-asserted-by":"publisher","first-page":"583","DOI":"10.1177\/0300060517692935","volume":"45","author":"A Alagl","year":"2017","unstructured":"Alagl A, Bedi S, Hassan K, AlHumaid J (2017) Use of platelet-rich plasma for regeneration in non-vital immature permanent teeth: clinical and cone-beam computed tomography evaluation. J Int Med Res 45:583\u2013593. https:\/\/doi.org\/10.1177\/0300060517692935","journal-title":"J Int Med Res"},{"key":"4123_CR72","doi-asserted-by":"publisher","first-page":"1517","DOI":"10.1016\/j.joen.2018.06.015","volume":"44","author":"N Meschi","year":"2018","unstructured":"Meschi N, Ezeldeen M, Lambrechts P (2018) Regenerative endodontics a retrospective case series in regenerative endodontics: trend analysis based on clinical evaluation and 2- and 3-dimensional radiology. J Endod 44:1517\u20131525. https:\/\/doi.org\/10.1016\/j.joen.2018.06.015","journal-title":"J Endod"},{"key":"4123_CR73","doi-asserted-by":"publisher","first-page":"720","DOI":"10.5005\/jp-journals-10024-2586","volume":"20","author":"N Mittal","year":"2019","unstructured":"Mittal N, Parashar V (2019) Regenerative evaluation of immature roots using PRF and artificial scaffolds in necrotic permanent teeth: a clinical study. J Contemp Dent Pract 20:720\u2013726. https:\/\/doi.org\/10.5005\/jp-journals-10024-2586","journal-title":"J Contemp Dent Pract"},{"key":"4123_CR74","doi-asserted-by":"publisher","first-page":"401","DOI":"10.1016\/j.joen.2016.10.016","volume":"43","author":"H Bakhtiar","year":"2017","unstructured":"Bakhtiar H, Esmaeili S, Fakhr Tabatabayi S et al (2017) Second-generation platelet concentrate (platelet-rich fibrin) as a scaffold in regenerative endodontics: a case series. J Endod 43:401\u2013408. https:\/\/doi.org\/10.1016\/j.joen.2016.10.016","journal-title":"J Endod"},{"key":"4123_CR75","doi-asserted-by":"publisher","first-page":"1620","DOI":"10.1016\/j.joen.2016.06.020","volume":"42","author":"BS Estefan","year":"2016","unstructured":"Estefan BS, El Batouty KM, Nagy MM, Diogenes A (2016) Influence of age and apical diameter on the success of endodontic regeneration procedures. J Endod 42:1620\u20131625. https:\/\/doi.org\/10.1016\/j.joen.2016.06.020","journal-title":"J Endod"},{"key":"4123_CR76","doi-asserted-by":"publisher","first-page":"463","DOI":"10.4317\/jced.57902","volume":"13","author":"V Jayadevan","year":"2021","unstructured":"Jayadevan V, Gehlot PM, Manjunath V et al (2021) A comparative evaluation of advanced platelet-rich fibrin (a-prf) and platelet-rich fibrin (prf) as a scaffold in regenerative endodontic treatment of traumatized immature non-vital permanent anterior teeth: a prospective clinical study. J Clin Exp Dent 13:463\u2013472. https:\/\/doi.org\/10.4317\/jced.57902","journal-title":"J Clin Exp Dent"},{"key":"4123_CR77","doi-asserted-by":"publisher","first-page":"441","DOI":"10.1016\/0030-4220(74)90119-4","volume":"37","author":"WC Myers","year":"1974","unstructured":"Myers WC, Fountain SB (1974) Dental pulp regeneration aided by blood and blood substitutes after experimentally induced periapical infection. Oral Surg Oral Med Oral Pathol 37:441\u2013450","journal-title":"Oral Surg Oral Med Oral Pathol"},{"key":"4123_CR78","doi-asserted-by":"publisher","first-page":"61","DOI":"10.1002\/JPER.17-0306","volume":"90","author":"A Kumar","year":"2019","unstructured":"Kumar A, Mahendra J, Samuel S et al (2019) Platelet-rich fibrin\/biphasic calcium phosphate impairs osteoclast differentiation and promotes apoptosis by the intrinsic mitochondrial pathway in chronic periodontitis. J Periodontol 90:61\u201371. https:\/\/doi.org\/10.1002\/JPER.17-0306","journal-title":"J Periodontol"},{"key":"4123_CR79","doi-asserted-by":"publisher","first-page":"413","DOI":"10.1002\/JPER.19-0109","volume":"91","author":"Z Kargarpour","year":"2020","unstructured":"Kargarpour Z, Nasirzade J, Strauss FJ et al (2020) Platelet-rich fibrin suppresses in vitro osteoclastogenesis. J Periodontol 91:413\u2013421. https:\/\/doi.org\/10.1002\/JPER.19-0109","journal-title":"J Periodontol"},{"key":"4123_CR80","doi-asserted-by":"publisher","first-page":"38","DOI":"10.1016\/j.archoralbio.2017.05.008","volume":"82","author":"V Hirsch","year":"2017","unstructured":"Hirsch V, Wolgin M, Mitronin AV, Kielbassa AM (2017) Inflammatory cytokines in normal and irreversibly inflamed pulps: a systematic review. Arch Oral Biol 82:38\u201346. https:\/\/doi.org\/10.1016\/j.archoralbio.2017.05.008","journal-title":"Arch Oral Biol"},{"key":"4123_CR81","doi-asserted-by":"publisher","first-page":"1309","DOI":"10.1007\/s00784-018-2555-2","volume":"23","author":"HA Varela","year":"2019","unstructured":"Varela HA, Souza JCM, Nascimento RM et al (2019) Injectable platelet rich fibrin: cell content, morphological, and protein characterization. Clin Oral Investig 23:1309\u20131318. https:\/\/doi.org\/10.1007\/s00784-018-2555-2","journal-title":"Clin Oral Investig"},{"key":"4123_CR82","doi-asserted-by":"publisher","first-page":"48","DOI":"10.1080\/09537104.2017.1293807","volume":"29","author":"X Wang","year":"2018","unstructured":"Wang X, Zhang Y, Choukroun J et al (2018) Effects of an injectable platelet-rich fibrin on osteoblast behavior and bone tissue formation in comparison to platelet-rich plasma. Platelets 29:48\u201355. https:\/\/doi.org\/10.1080\/09537104.2017.1293807","journal-title":"Platelets"}],"container-title":["Clinical Oral Investigations"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00784-021-04123-z.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s00784-021-04123-z\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00784-021-04123-z.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,2,4]],"date-time":"2022-02-04T07:10:09Z","timestamp":1643958609000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s00784-021-04123-z"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,8,13]]},"references-count":82,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2022,2]]}},"alternative-id":["4123"],"URL":"https:\/\/doi.org\/10.1007\/s00784-021-04123-z","relation":{},"ISSN":["1432-6981","1436-3771"],"issn-type":[{"value":"1432-6981","type":"print"},{"value":"1436-3771","type":"electronic"}],"subject":[],"published":{"date-parts":[[2021,8,13]]},"assertion":[{"value":"16 February 2021","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"30 July 2021","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"13 August 2021","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"All procedures performed in studies involving human participants were in accordance with the ethical standards of the institutional and\/or national research committee and with the 1964 Helsinki Declaration and its later amendments or comparable ethical standards. The study was approved by the Ethical Committee of the Faculty of Medicine Fayoum University (R121).","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethics approval"}},{"value":"Informed consent was obtained from all individual participants included in the study or from the parents of the children included in the study.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent to participate"}},{"value":"The authors affirm that the patient\/parent\/guardian\/ relative of the patient provided informed consent for publication of their clinical details and\/or clinical images which was obtained from them.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent for publication"}},{"value":"The authors declare no competing interests.","order":5,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of interest"}}]}}