{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,11]],"date-time":"2026-10-11T05:15:48Z","timestamp":1791695748859,"version":"4.3.4"},"reference-count":38,"publisher":"Springer Science and Business Media LLC","issue":"2","license":[{"start":{"date-parts":[[2021,9,2]],"date-time":"2021-09-02T00:00:00Z","timestamp":1630540800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"},{"start":{"date-parts":[[2021,9,2]],"date-time":"2021-09-02T00:00:00Z","timestamp":1630540800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"}],"funder":[{"name":"Alma Mater Studiorum - Universit\u00e0 di Bologna"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Clin Oral Invest"],"published-print":{"date-parts":[[2022,2]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec>\n                <jats:title>Objective<\/jats:title>\n                <jats:p>To investigate the long-term microtensile bond strength (\u00b5TBS), interfacial nanoleakage expression (NL), and adhesive stability of dual-cure resin cements with\/out light activation to dentin.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Materials and methods<\/jats:title>\n                <jats:p>Composite overlays (<jats:italic>N<\/jats:italic>\u2009=\u200920) were luted to deep dentin surfaces with RelyX Ultimate (RXU, 3M) or Variolink EstheticDC (VAR, Ivoclar-Vivadent). A universal adhesive was used for bonding procedures (iBond universal, Heraeus Kulzer). The resin cements were either self-cured (SC; 1\u00a0h at 37\u00a0\u00b0C) or dual-cured (DC; 20s light-cure followed by 15\u00a0min self-cure at 37\u00a0\u00b0C). Specimens were submitted to \u00b5TBS immediately (<jats:italic>T<\/jats:italic><jats:sub>0<\/jats:sub>) or after 1\u00a0year of laboratory storage (<jats:italic>T<\/jats:italic><jats:sub>12<\/jats:sub>). The fracture pattern was evaluated using scanning electron microscopy (SEM). Data were statistically analyzed with two-way ANOVA\/Tukey test. Further, the NL was quantified and analyzed (chi-square test) and in situ zymography was performed to evaluate the endogenous enzymatic activity within the hybrid layer (HL) at <jats:italic>T<\/jats:italic><jats:sub>0<\/jats:sub> and <jats:italic>T<\/jats:italic><jats:sub>12<\/jats:sub> (Mann\u2013Whitney test)<jats:sub>.<\/jats:sub> The significance level for all statistical tests was set at <jats:italic>p<\/jats:italic>\u2009=\u20090.05.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Results<\/jats:title>\n                <jats:p>DC resulted in higher bond strength and decreased fluorescence at the adhesive interface, irrespective of the material and the storage period (<jats:italic>p<\/jats:italic>\u2009&lt;\u20090.05). Significantly lower bonding performances (<jats:italic>p<\/jats:italic>\u2009&lt;\u20090.05) and higher endogenous enzymatic activity (<jats:italic>p<\/jats:italic>\u2009&lt;\u20090.05) were observed within the HL at <jats:italic>T<\/jats:italic><jats:sub>12<\/jats:sub> compared to <jats:italic>T<\/jats:italic><jats:sub>0<\/jats:sub> in all tested groups.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Conclusions<\/jats:title>\n                <jats:p>Light-curing the dual-cure resin cements, more than the cement materials, accounted for good bonding performances and higher HL stability over time when used with a universal adhesive.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Clinical significance<\/jats:title>\n                <jats:p>The curing condition influences the bonding performances of dual-cure resin cements to dentin when used with a universal adhesive.<\/jats:p>\n              <\/jats:sec>","DOI":"10.1007\/s00784-021-04141-x","type":"journal-article","created":{"date-parts":[[2021,9,1]],"date-time":"2021-09-01T23:22:15Z","timestamp":1630538535000},"page":"1683-1694","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":32,"title":["Influence of the activation mode on long-term bond strength and endogenous enzymatic activity of dual-cure resin cements"],"prefix":"10.1007","volume":"26","author":[{"given":"Claudia","family":"Mazzitelli","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tatjana","family":"Maravic","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Edoardo","family":"Mancuso","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Uros","family":"Josic","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Luigi","family":"Generali","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Allegra","family":"Comba","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Annalisa","family":"Mazzoni","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7621-226X","authenticated-orcid":false,"given":"Lorenzo","family":"Breschi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2021,9,2]]},"reference":[{"key":"4141_CR1","doi-asserted-by":"publisher","first-page":"418","DOI":"10.1016\/j.jdent.2008.02.014","volume":"36","author":"CAG Arrais","year":"2008","unstructured":"Arrais CAG, Rueggeberg FA, Waller JL, de Goes MF, Giannini M (2008) Effect of curing mode on the polymerization characteristics of dual-cured resin cement systems. 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