{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,21]],"date-time":"2026-09-21T20:42:24Z","timestamp":1790023344369,"version":"4.0.1"},"reference-count":45,"publisher":"Springer Science and Business Media LLC","issue":"2","license":[{"start":{"date-parts":[[2021,8,24]],"date-time":"2021-08-24T00:00:00Z","timestamp":1629763200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"},{"start":{"date-parts":[[2021,8,24]],"date-time":"2021-08-24T00:00:00Z","timestamp":1629763200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Clin Oral Invest"],"published-print":{"date-parts":[[2022,2]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec>\n                <jats:title>Objectives<\/jats:title>\n                <jats:p>To investigate effects of root conditioning with 24% ethylenediaminetetraacetic acid (EDTA) on the 12-month outcomes after treatment of multiple gingival recessions (GR) with modified coronally advanced tunnel (MCAT) and subepithelial connective tissue graft (SCTG).<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Materials and methods<\/jats:title>\n                <jats:p>Twenty patients with 142 GR were treated (72 test sites: SCTG\u2009+\u2009EDTA and 70 control sites: SCTG). Average and complete root coverage (ARC, CRC), gain in keratinized tissue width (KTW), gain in gingival thickness (GT), root esthetic coverage score (RES), and patient-reported outcome measures (PROMs) were evaluated at 12\u00a0months post-operatively.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Results<\/jats:title>\n                <jats:p>Differences between pre- and post-operative values were statistically significant only within but not between treatment modalities. At 12\u00a0months, ARC was 86.0% for SCTG\u2009+\u2009EDTA-treated and 84.6 for SCTG-treated defects (<jats:italic>p<\/jats:italic>\u2009=\u20090.6636). CRC was observed in 90.2% (tests) and 91.4% (controls) of all cases (<jats:italic>p<\/jats:italic>\u2009=\u20090.9903). Professional assessment of esthetic outcomes using RES showed highly positive results reaching the value of 8.9 in case of test sites and 8.7 for control sites (<jats:italic>p<\/jats:italic>\u2009=\u20090.3358). Severity of pain and swelling did not differ between sites, regardless of whether EDTA was used.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Conclusions<\/jats:title>\n                <jats:p>Test and control sites presented similarly positive outcomes related to root coverage, periodontal and esthetic parameters, and patient satisfaction and self-reported morbidity with no statistical differences between them 12\u00a0months after surgery. No significant differences in evaluated variables were observed between sites treated with and without 24% EDTA.<\/jats:p>\n                <jats:p>Clinical relevance<\/jats:p>\n                <jats:p>Considering the limitations of the present study, the use of 24% EDTA for root conditioning did not improve 12-month outcomes after treatment of multiple RT1 and RT2 gingival recessions with MCAT and SCTG.<\/jats:p>\n                <jats:p>Trial registration<\/jats:p>\n                <jats:p>ClinicalTrials.gov identifier: NCT03354104<\/jats:p>\n              <\/jats:sec>","DOI":"10.1007\/s00784-021-04151-9","type":"journal-article","created":{"date-parts":[[2021,8,24]],"date-time":"2021-08-24T19:02:42Z","timestamp":1629831762000},"page":"1761-1772","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":18,"title":["Effect of 24% EDTA root conditioning on the outcome of modified coronally advanced tunnel technique with subepithelial connective tissue graft for the treatment of multiple gingival recessions: a randomized clinical trial"],"prefix":"10.1007","volume":"26","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-3918-4332","authenticated-orcid":false,"given":"Bart\u0142omiej","family":"G\u00f3rski","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marcin","family":"Szersze\u0144","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tomasz","family":"Kaczy\u0144ski","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2021,8,24]]},"reference":[{"issue":"1","key":"4151_CR1","doi-asserted-by":"publisher","first-page":"112","DOI":"10.1111\/jcpe.13383","volume":"48","author":"FS Rios","year":"2021","unstructured":"Rios FS, Costa RSA, Wagner TP, Christofoli BR, Goergen J, Izquierdo C, Jardim JJ, Maltz M, Haas AN (2021) Incidence and progression of gingival recession over 4 years: a population-based longitudinal study. 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If material is not included in the article's Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit .","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Open Access"}}]}}