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This study aimed to compare the effectiveness of mineralized plasmatic matrix (MPM) versus cancellous bone particles harvested from anterior iliac crest in secondary alveolar cleft grafting.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Patients and methods<\/jats:title>\n                <jats:p>This prospective randomized controlled trial was conducted on ten patients with unilateral complete alveolar cleft requiring cleft reconstruction. Patients were randomly divided into two equal groups; group (1) included 5 patients who received particulate cancellous bone derived from anterior iliac crest (control group) and group (2) included 5 patients who received MPM graft prepared from cancellous bone derived from anterior iliac crest (study group). All patients received CBCT preoperatively, immediately postoperatively and after 6\u00a0months. On the CBCT, graft\u2019s volume, labio-palatal width, and height were measured and compared.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Results<\/jats:title>\n                <jats:p>The outcome of the studied patients 6\u00a0months postoperatively showed that the control group had significant decrease in the graft volume, labio-palatal width, and height compared to the study group.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Conclusion<\/jats:title>\n                <jats:p>MPM allowed for the integration of bone graft particles inside a fibrin network, which offers positional stability of the bone particles, thus preserving their shape with subsequent \u201cin situ\u201d immobilization of the graft components. This conclusion was reflected positively in terms of maintained graft volume, width, and height compared to that of the control group.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Clinical relevance<\/jats:title>\n                <jats:p>MPM allowed for maintenance of grafted ridge volume, width, and height.<\/jats:p>\n              <\/jats:sec>","DOI":"10.1007\/s00784-023-05042-x","type":"journal-article","created":{"date-parts":[[2023,5,5]],"date-time":"2023-05-05T05:01:45Z","timestamp":1683262905000},"page":"4259-4270","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":11,"title":["Secondary alveolar cleft grafting using autogenous mineralized plasmatic matrix (MPM) versus cancellous bone particles derived from anterior iliac crest"],"prefix":"10.1007","volume":"27","author":[{"given":"Mohammed","family":"Omara","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Louai","family":"Raafat","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tarek","family":"Elfaramawi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2023,5,5]]},"reference":[{"issue":"2","key":"5042_CR1","first-page":"87","volume":"30","author":"PJ Boyne","year":"1972","unstructured":"Boyne PJ, Sands NR (1972) Secondary bone grafting of residual alveolar and palatal clefts. 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