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However, the use and efficacy of these interventions have only partially been evaluated. The present study aims to investigate whether there is an association between the perceived oral dryness and discomfort of SjD patients and their use of specific interventions.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Materials and methods<\/jats:title>\n                    <jats:p>A cross-sectional study was performed among SjD patients, who completed several questionnaires to assess the severity of their oral dryness and an inventory of dry-mouth interventions. The perceived efficacy of each intervention was reported on a 5-point Likert-scale.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>The questionnaires were returned by 92 SjD patients. For relief of oral dryness, they mostly used \u201ceating fruit\u201d, \u201cdrinking tea\u201d, \u201cmoistening the lips\u201d, \u201cdrinking water, and \u201cdrinking small volumes\u201d (&gt;\u200950%). Three interventions had a frequency of use ranging from 2\u20136 times\/day, whereas, \u201cdrinking water\u201d and \u201cdrinking small volumes\u201d showed higher frequencies (&gt;\u200914). The highest overall efficacy (\u2265\u20093.5) was reported for \u201cchewing gum\u201d and \u201cusing a mouth gel\u201d. Furthermore, various dry-mouth interventions showed significant associations with oral dryness scores and\/or patients\u2019 discomfort. For example, \u201cdrinking small volumes\u201d and \u201cusing XyliMelts\u201d were associated with the Bother Index score.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Great variation was found in the use of dry-mouth interventions by the participants and the severity of the oral dryness and\/or patients\u2019 discomfort seemed to affect their choice of intervention. Notably, the mostly used interventions did not show the highest reported efficacy.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Clinical relevance<\/jats:title>\n                    <jats:p>These findings might help SjD patients and clinicians in their choice of effective dry-mouth interventions.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1007\/s00784-023-05172-2","type":"journal-article","created":{"date-parts":[[2023,7,28]],"date-time":"2023-07-28T12:02:01Z","timestamp":1690545721000},"page":"5529-5537","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":4,"title":["Use and efficacy of dry-mouth interventions in Sj\u00f6gren\u2019s disease patients and possible association with perceived oral dryness and patients\u2019 discomfort"],"prefix":"10.1007","volume":"27","author":[{"given":"Z.","family":"Assy","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J. 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