{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,24]],"date-time":"2026-10-24T01:24:16Z","timestamp":1792805056357,"version":"4.5.0"},"reference-count":68,"publisher":"Springer Science and Business Media LLC","issue":"10","license":[{"start":{"date-parts":[[2023,8,24]],"date-time":"2023-08-24T00:00:00Z","timestamp":1692835200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"},{"start":{"date-parts":[[2023,8,24]],"date-time":"2023-08-24T00:00:00Z","timestamp":1692835200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["81901044"],"award-info":[{"award-number":["81901044"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"name":"Chinese Stomatological Association COS Basic Research Fund","award":["No. COS-B2021-08"],"award-info":[{"award-number":["No. COS-B2021-08"]}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Clin Oral Invest"],"DOI":"10.1007\/s00784-023-05216-7","type":"journal-article","created":{"date-parts":[[2023,8,24]],"date-time":"2023-08-24T17:02:30Z","timestamp":1692896550000},"page":"6027-6042","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":22,"title":["In vitro evaluation of a novel fluoride-coated clear aligner with antibacterial and enamel remineralization abilities"],"prefix":"10.1007","volume":"27","author":[{"given":"Jiarong","family":"Yan","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lingyun","family":"Cao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ting","family":"Luo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Danchen","family":"Qin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fang","family":"Hua","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hong","family":"He","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2023,8,24]]},"reference":[{"key":"5216_CR1","unstructured":"Proffit WR, Fields HW, Larson Be, Sarver DM (2018) Contemporary orthodontics. Sixth ed. Mosby, Saint Louis"},{"issue":"Suppl 1","key":"5216_CR2","doi-asserted-by":"publisher","first-page":"58","DOI":"10.1111\/adj.12480","volume":"62","author":"T Weir","year":"2017","unstructured":"Weir T (2017) Clear aligners in orthodontic treatment. Aust Dent J 62(Suppl 1):58\u201362. https:\/\/doi.org\/10.1111\/adj.12480","journal-title":"Aust Dent J"},{"key":"5216_CR3","doi-asserted-by":"publisher","first-page":"430","DOI":"10.1007\/s00056-010-1040-6","volume":"71","author":"I Schaefer","year":"2010","unstructured":"Schaefer I, Braumann B (2010) Halitosis, Oral health and quality of life during treatment with Invisalign(\u00ae) and the effect of a low-dose chlorhexidine solution. J Orofac Orthop 71:430\u2013441. https:\/\/doi.org\/10.1007\/s00056-010-1040-6","journal-title":"J Orofac Orthop"},{"key":"5216_CR4","doi-asserted-by":"publisher","first-page":"64","DOI":"10.1186\/s40510-014-0064-7","volume":"15","author":"K Fujiyama","year":"2014","unstructured":"Fujiyama K, Honjo T, Suzuki M, Matsuoka S, Deguchi T (2014) Analysis of pain level in cases treated with Invisalign aligner: comparison with fixed edgewise appliance therapy. Prog Orthod 15:64. https:\/\/doi.org\/10.1186\/s40510-014-0064-7","journal-title":"Prog Orthod"},{"key":"5216_CR5","doi-asserted-by":"publisher","first-page":"276.e1","DOI":"10.1016\/j.ajodo.2008.09.020","volume":"135","author":"MD Rosvall","year":"2009","unstructured":"Rosvall MD, Fields HW, Ziuchkovski J, Rosenstiel SF, Johnston WM (2009) Attractiveness, acceptability, and value of orthodontic appliances. Am J Orthod Dentofacial Orthop 135:276.e1\u201312. https:\/\/doi.org\/10.1016\/j.ajodo.2008.09.020. (discussion 276-277)","journal-title":"Am J Orthod Dentofacial Orthop"},{"key":"5216_CR6","doi-asserted-by":"publisher","first-page":"391","DOI":"10.2319\/062113-466","volume":"84","author":"PH Buschang","year":"2014","unstructured":"Buschang PH, Shaw SG, Ross M, Crosby D, Campbell PM (2014) Comparative time efficiency of aligner therapy and conventional edgewise braces. Angle Orthod 84:391\u2013396. https:\/\/doi.org\/10.2319\/062113-466","journal-title":"Angle Orthod"},{"key":"5216_CR7","doi-asserted-by":"publisher","first-page":"881","DOI":"10.2319\/061614-436.1","volume":"85","author":"G Rossini","year":"2015","unstructured":"Rossini G, Parrini S, Castroflorio T, Deregibus A, Debernardi CL (2015) Efficacy of clear aligners in controlling orthodontic tooth movement: a systematic review. Angle Orthod 85:881\u2013889. https:\/\/doi.org\/10.2319\/061614-436.1","journal-title":"Angle Orthod"},{"key":"5216_CR8","doi-asserted-by":"publisher","first-page":"745","DOI":"10.1016\/j.ajodo.2019.05.023","volume":"157","author":"D Fang","year":"2020","unstructured":"Fang D, Li F, Zhang Y, Bai Y, Wu BM (2020) Changes in mechanical properties, surface morphology, structure, and composition of Invisalign material in the oral environment. Am J Orthod Dentofacial Orthop 157:745\u2013753. https:\/\/doi.org\/10.1016\/j.ajodo.2019.05.023","journal-title":"Am J Orthod Dentofacial Orthop"},{"key":"5216_CR9","first-page":"494","volume":"47","author":"M Moshiri","year":"2013","unstructured":"Moshiri M, Eckhart JE, McShane P, German DS (2013) Consequences of poor oral hygiene during aligner therapy. J Clin Orthod 47:494\u2013498","journal-title":"J Clin Orthod"},{"key":"5216_CR10","doi-asserted-by":"publisher","first-page":"641","DOI":"10.2319\/071712-584.1","volume":"83","author":"KC Julien","year":"2013","unstructured":"Julien KC, Buschang PH, Campbell PM (2013) Prevalence of white spot lesion formation during orthodontic treatment. Angle Orthod 83:641\u2013647. https:\/\/doi.org\/10.2319\/071712-584.1","journal-title":"Angle Orthod"},{"key":"5216_CR11","doi-asserted-by":"publisher","first-page":"664","DOI":"10.1093\/ejo\/cjs070","volume":"35","author":"A Lucchese","year":"2013","unstructured":"Lucchese A, Gherlone E (2013) Prevalence of white-spot lesions before and during orthodontic treatment with fixed appliances. Eur J Orthod 35:664\u2013668. https:\/\/doi.org\/10.1093\/ejo\/cjs070","journal-title":"Eur J Orthod"},{"key":"5216_CR12","doi-asserted-by":"publisher","first-page":"633","DOI":"10.1016\/j.ajodo.2018.11.017","volume":"156","author":"Q Wang","year":"2019","unstructured":"Wang Q, Ma JB, Wang B, Zhang X, Yin YL, Bai H (2019) Alterations of the oral microbiome in patients treated with the Invisalign system or with fixed appliances. Am J Orthod Dentofacial Orthop 156:633\u2013640. https:\/\/doi.org\/10.1016\/j.ajodo.2018.11.017","journal-title":"Am J Orthod Dentofacial Orthop"},{"key":"5216_CR13","doi-asserted-by":"publisher","first-page":"25","DOI":"10.1186\/s40510-018-0230-4","volume":"19","author":"I Sifakakis","year":"2018","unstructured":"Sifakakis I, Papaioannou W, Papadimitriou A, Kloukos D, Papageorgiou SN, Eliades T (2018) Salivary levels of cariogenic bacterial species during orthodontic treatment with thermoplastic aligners or fixed appliances: a prospective cohort study. Prog Orthod 19:25. https:\/\/doi.org\/10.1186\/s40510-018-0230-4","journal-title":"Prog Orthod"},{"key":"5216_CR14","doi-asserted-by":"publisher","first-page":"594","DOI":"10.1016\/j.ajodo.2020.01.004","volume":"157","author":"Z Albhaisi","year":"2020","unstructured":"Albhaisi Z, Al-Khateeb SN, Abu Alhaija ES (2020) Enamel demineralization during clear aligner orthodontic treatment compared with fixed appliance therapy, evaluated with quantitative light-induced fluorescence: a randomized clinical trial. Am J Orthod Dentofacial Orthop 157:594\u2013601. https:\/\/doi.org\/10.1016\/j.ajodo.2020.01.004","journal-title":"Am J Orthod Dentofacial Orthop"},{"key":"5216_CR15","doi-asserted-by":"publisher","first-page":"413","DOI":"10.3109\/00016357.2013.859728","volume":"72","author":"A Borzabadi-Farahani","year":"2014","unstructured":"Borzabadi-Farahani A, Borzabadi E, Lynch E (2014) Nanoparticles in orthodontics, a review of antimicrobial and anti-caries applications. Acta Odontol Scand 72:413\u2013417. https:\/\/doi.org\/10.3109\/00016357.2013.859728","journal-title":"Acta Odontol Scand"},{"key":"5216_CR16","doi-asserted-by":"publisher","first-page":"3257","DOI":"10.3390\/ma13153257","volume":"13","author":"J B\u0105cela","year":"2020","unstructured":"B\u0105cela J, \u0141abowska MB, Detyna J, Zi\u0119ty A, Michalak I (2020) Functional coatings for orthodontic archwires-a review. Materials (Basel) 13:3257. https:\/\/doi.org\/10.3390\/ma13153257","journal-title":"Materials (Basel)"},{"key":"5216_CR17","doi-asserted-by":"publisher","first-page":"53","DOI":"10.1016\/j.jdent.2018.03.004","volume":"72","author":"Y Liu","year":"2018","unstructured":"Liu Y, Zhang L, Niu LN, Yu T, Xu HHK, Weir MD, Oates TW, Tay FR, Chen JH (2018) Antibacterial and remineralizing orthodontic adhesive containing quaternary ammonium resin monomer and amorphous calcium phosphate nanoparticles. J Dent 72:53\u201363. https:\/\/doi.org\/10.1016\/j.jdent.2018.03.004","journal-title":"J Dent"},{"key":"5216_CR18","doi-asserted-by":"publisher","first-page":"41787","DOI":"10.1038\/srep41787","volume":"7","author":"F Yu","year":"2017","unstructured":"Yu F, Dong Y, Yu HH, Lin PT, Zhang L, Sun X, Liu Y, Xia YN, Huang L, Chen JH (2017) Antibacterial activity and bonding ability of an orthodontic adhesive containing the antibacterial monomer 2-methacryloxylethyl hexadecyl methyl ammonium bromide. Sci Rep 7:41787. https:\/\/doi.org\/10.1038\/srep41787","journal-title":"Sci Rep"},{"key":"5216_CR19","doi-asserted-by":"publisher","first-page":"249","DOI":"10.1016\/j.jds.2021.03.016","volume":"17","author":"A Ali","year":"2022","unstructured":"Ali A, Ismail H, Amin K (2022) Effect of nanosilver mouthwash on prevention of white spot lesions in patients undergoing fixed orthodontic treatment - a randomized double-blind clinical trial. J Dent Sci 17:249\u2013255. https:\/\/doi.org\/10.1016\/j.jds.2021.03.016","journal-title":"J Dent Sci"},{"key":"5216_CR20","doi-asserted-by":"publisher","first-page":"21","DOI":"10.1016\/j.ajodo.2019.10.025","volume":"159","author":"TR Bauer Faria","year":"2021","unstructured":"Bauer Faria TR, Furletti-Goes VF, Franzini CM, de Aro AA, de Andrade TAM, Sartoratto A, de Menezes CC (2021) Anti-inflammatory and antimicrobial effects of Zingiber officinale mouthwash on patients with fixed orthodontic appliances. Am J Orthod Dentofacial Orthop 159:21\u201329. https:\/\/doi.org\/10.1016\/j.ajodo.2019.10.025","journal-title":"Am J Orthod Dentofacial Orthop"},{"key":"5216_CR21","doi-asserted-by":"publisher","first-page":"204","DOI":"10.2319\/052521-418.1","volume":"92","author":"LN Flynn","year":"2022","unstructured":"Flynn LN, Julien K, Noureldin A, Buschang PH (2022) The efficacy of fluoride varnish vs a filled resin sealant for preventing white spot lesions during orthodontic treatment. Angle Orthod 92:204\u2013212. https:\/\/doi.org\/10.2319\/052521-418.1","journal-title":"Angle Orthod"},{"key":"5216_CR22","doi-asserted-by":"publisher","first-page":"465","DOI":"10.1186\/s12903-021-01805-8","volume":"21","author":"P Poornima","year":"2021","unstructured":"Poornima P, Krithikadatta J, Ponraj RR, Velmurugan N, Kishen A (2021) Biofilm formation following chitosan-based varnish or chlorhexidine-fluoride varnish application in patients undergoing fixed orthodontic treatment: a double blinded randomised controlled trial. BMC Oral Health 21:465. https:\/\/doi.org\/10.1186\/s12903-021-01805-8","journal-title":"BMC Oral Health"},{"key":"5216_CR23","doi-asserted-by":"publisher","first-page":"1239","DOI":"10.1021\/acsbiomaterials.9b01647","volume":"6","author":"Y Xie","year":"2020","unstructured":"Xie Y, Zhang M, Zhang W, Liu X, Zheng W, Jiang X (2020) Gold nanoclusters-coated orthodontic devices can inhibit the formation of Streptococcus mutans biofilm. ACS Biomater Sci Eng 6:1239\u20131246. https:\/\/doi.org\/10.1021\/acsbiomaterials.9b01647","journal-title":"ACS Biomater Sci Eng"},{"key":"5216_CR24","doi-asserted-by":"publisher","first-page":"955","DOI":"10.1139\/m95-133","volume":"41","author":"RE Marquis","year":"1995","unstructured":"Marquis RE (1995) Antimicrobial actions of fluoride for oral bacteria. Can J Microbiol 41:955\u2013964. https:\/\/doi.org\/10.1139\/m95-133","journal-title":"Can J Microbiol"},{"key":"5216_CR25","doi-asserted-by":"publisher","first-page":"179","DOI":"10.5644\/ama2006-124.85","volume":"42","author":"K Ro\u0161in-Grget","year":"2013","unstructured":"Ro\u0161in-Grget K, Pero\u0161 K, Sutej I, Ba\u0161i\u0107 K (2013) The cariostatic mechanisms of fluoride. Acta Med Acad 42:179\u2013188. https:\/\/doi.org\/10.5644\/ama2006-124.85","journal-title":"Acta Med Acad"},{"key":"5216_CR26","doi-asserted-by":"publisher","first-page":"606","DOI":"10.1177\/00220345900690S119","volume":"69","author":"HC Margolis","year":"1990","unstructured":"Margolis HC, Moreno EC (1990) Physicochemical perspectives on the cariostatic mechanisms of systemic and topical fluorides. J Dent Res 69:606\u2013613. https:\/\/doi.org\/10.1177\/00220345900690S119. (discussion:634-636)","journal-title":"J Dent Res"},{"key":"5216_CR27","doi-asserted-by":"publisher","first-page":"1119","DOI":"10.1016\/j.dental.2015.06.010","volume":"31","author":"N Zhang","year":"2015","unstructured":"Zhang N, Melo MA, Chen C, Liu J, Weir MD, Bai Y, Xu HH (2015) Development of a multifunctional adhesive system for prevention of root caries and secondary caries. Dent Mater 31:1119\u20131131. https:\/\/doi.org\/10.1016\/j.dental.2015.06.010","journal-title":"Dent Mater"},{"key":"5216_CR28","doi-asserted-by":"publisher","first-page":"318","DOI":"10.2341\/15-015-L","volume":"41","author":"Y Kim","year":"2016","unstructured":"Kim Y, Son HH, Yi K, Ahn JS, Chang J (2016) Bleaching effects on color, chemical, and mechanical properties of white spot lesions. Oper Dent 41:318\u2013326. https:\/\/doi.org\/10.2341\/15-015-L","journal-title":"Oper Dent"},{"key":"5216_CR29","doi-asserted-by":"publisher","first-page":"139","DOI":"10.1007\/s00784-012-0680-x","volume":"17","author":"Y Kim","year":"2013","unstructured":"Kim Y, Son HH, Yi K, Kim HY, Ahn J, Chang J (2013) The color change in artificial white spot lesions measured using a spectroradiometer. Clin Oral Investig 17:139\u2013146. https:\/\/doi.org\/10.1007\/s00784-012-0680-x","journal-title":"Clin Oral Investig"},{"key":"5216_CR30","doi-asserted-by":"publisher","first-page":"4011","DOI":"10.1007\/s00784-020-03732-4","volume":"25","author":"EE Jansen","year":"2021","unstructured":"Jansen EE, Meyer-Lueckel H, Esteves-Oliveira M, Wierichs RJ (2021) Do bleaching gels affect the stability of the masking and caries-arresting effects of caries infiltration-in vitro. Clin Oral Investig 25:4011\u20134021. https:\/\/doi.org\/10.1007\/s00784-020-03732-4","journal-title":"Clin Oral Investig"},{"key":"5216_CR31","doi-asserted-by":"publisher","first-page":"2079","DOI":"10.1007\/s00784-019-03073-x","volume":"24","author":"F Hua","year":"2020","unstructured":"Hua F, Yan J, Zhao S, Yang H, He H (2020) In vitro remineralization of enamel white spot lesions with a carrier-based amorphous calcium phosphate delivery system. Clin Oral Investig 24:2079\u20132089. https:\/\/doi.org\/10.1007\/s00784-019-03073-x","journal-title":"Clin Oral Investig"},{"key":"5216_CR32","doi-asserted-by":"publisher","first-page":"103729","DOI":"10.1016\/j.jdent.2021.103729","volume":"111","author":"JY Niu","year":"2021","unstructured":"Niu JY, Yin IX, Wu WKK, Li QL, Mei ML, Chu CH (2021) A novel dual-action antimicrobial peptide for caries management. J Dent 111:103729. https:\/\/doi.org\/10.1016\/j.jdent.2021.103729","journal-title":"J Dent"},{"key":"5216_CR33","doi-asserted-by":"publisher","first-page":"202","DOI":"10.1111\/eos.12187","volume":"123","author":"N Kohda","year":"2015","unstructured":"Kohda N, Iijima M, Kawaguchi K, Toshima H, Muguruma T, Endo K, Mizoguchi I (2015) Inhibition of enamel demineralization and bond-strength properties of bioactive glass containing 4-META\/MMA-TBB-based resin adhesive. Eur J Oral Sci 123:202\u2013207. https:\/\/doi.org\/10.1111\/eos.12187","journal-title":"Eur J Oral Sci"},{"key":"5216_CR34","doi-asserted-by":"publisher","first-page":"e12784","DOI":"10.1111\/eos.12784","volume":"129","author":"Y Zhu","year":"2021","unstructured":"Zhu Y, Yan J, Mujtaba BM, Li Y, Wei H, Huang S (2021) The dual anti-caries effect of carboxymethyl chitosan nanogel loaded with chimeric lysin ClyR and amorphous calcium phosphate. Eur J Oral Sci 129:e12784. https:\/\/doi.org\/10.1111\/eos.12784","journal-title":"Eur J Oral Sci"},{"key":"5216_CR35","doi-asserted-by":"publisher","first-page":"2079","DOI":"10.1007\/s00784-019-03073-x","volume":"24","author":"F Hua","year":"2019","unstructured":"Hua F, Yan J, Zhao S, Yang H, He H (2019) In vitro remineralization of enamel white spot lesions with a carrier-based amorphous calcium phosphate delivery system. Clin Oral Investig 24:2079\u20132089. https:\/\/doi.org\/10.1007\/s00784-019-03073-x","journal-title":"Clin Oral Investig"},{"key":"5216_CR36","doi-asserted-by":"publisher","first-page":"1154","DOI":"10.1016\/j.dental.2018.04.010","volume":"34","author":"J Zhang","year":"2018","unstructured":"Zhang J, Boyes V, Festy F, Lynch RJM, Watson TF, Banerjee A (2018) In-vitro subsurface remineralisation of artificial enamel white spot lesions pre-treated with chitosan. Dent Mater 34:1154\u20131167. https:\/\/doi.org\/10.1016\/j.dental.2018.04.010","journal-title":"Dent Mater"},{"key":"5216_CR37","doi-asserted-by":"publisher","first-page":"69","DOI":"10.1186\/s12903-015-0060-4","volume":"15","author":"A Azaripour","year":"2015","unstructured":"Azaripour A, Weusmann J, Mahmoodi B, Peppas D, Gerhold-Ay A, Van Noorden CJ, Willershausen B (2015) Braces versus Invisalign\u00ae: gingival parameters and patients\u2019 satisfaction during treatment: a cross-sectional study. BMC Oral Health 15:69. https:\/\/doi.org\/10.1186\/s12903-015-0060-4","journal-title":"BMC Oral Health"},{"key":"5216_CR38","doi-asserted-by":"publisher","first-page":"639","DOI":"10.1016\/j.ajodo.2018.01.013","volume":"154","author":"C Flores-Mir","year":"2018","unstructured":"Flores-Mir C, Brandelli J, Pacheco-Pereira C (2018) Patient satisfaction and quality of life status after 2 treatment modalities: Invisalign and conventional fixed appliances. Am J Orthod Dentofacial Orthop 154:639\u2013644. https:\/\/doi.org\/10.1016\/j.ajodo.2018.01.013","journal-title":"Am J Orthod Dentofacial Orthop"},{"key":"5216_CR39","doi-asserted-by":"publisher","first-page":"240","DOI":"10.1007\/s00056-015-0285-5","volume":"76","author":"GM Abbate","year":"2015","unstructured":"Abbate GM, Caria MP, Montanari P, Mannu C, Orr\u00f9 G, Caprioglio A, Levrini L (2015) Periodontal health in teenagers treated with removable aligners and fixed orthodontic appliances. J Orofac Orthop 76:240\u2013250. https:\/\/doi.org\/10.1007\/s00056-015-0285-5","journal-title":"J Orofac Orthop"},{"key":"5216_CR40","volume-title":"Chemistry and chemical reactivity","author":"JC Kotz","year":"2011","unstructured":"Kotz JC, Treichel PM, Moran MJ (2011) Chemistry and chemical reactivity, 8th edn. CENGAGE Learning, Boston","edition":"8"},{"key":"5216_CR41","doi-asserted-by":"publisher","first-page":"26","DOI":"10.1186\/s40510-017-0178-9","volume":"18","author":"L Lombardo","year":"2017","unstructured":"Lombardo L, Martini M, Cervinara F, Spedicato GA, Oliverio T, Siciliani G (2017) Comparative SEM analysis of nine F22 aligner cleaning strategies. Prog Orthod 18:26. https:\/\/doi.org\/10.1186\/s40510-017-0178-9","journal-title":"Prog Orthod"},{"key":"5216_CR42","doi-asserted-by":"publisher","first-page":"1041","DOI":"10.1111\/j.1365-2842.2004.01350.x","volume":"31","author":"D Steinberg","year":"2004","unstructured":"Steinberg D, Eyal S (2004) Initial biofilm formation of Streptococcus sobrinus on various orthodontics appliances. J Oral Rehabil 31:1041\u20131045. https:\/\/doi.org\/10.1111\/j.1365-2842.2004.01350.x","journal-title":"J Oral Rehabil"},{"key":"5216_CR43","doi-asserted-by":"publisher","first-page":"4436","DOI":"10.3390\/polym13244436","volume":"13","author":"AC Ambarita","year":"2021","unstructured":"Ambarita AC, Mulyati S, Arahman N, Bilad MR, Shamsuddin N, Ismail NM (2021) Improvement of properties and performances of polyethersulfone ultrafiltration membrane by blending with bio-based dragonbloodin resin. Polymers (Basel) 13:4436. https:\/\/doi.org\/10.3390\/polym13244436","journal-title":"Polymers (Basel)"},{"key":"5216_CR44","doi-asserted-by":"publisher","first-page":"16723","DOI":"10.1038\/s41598-019-53243-w","volume":"9","author":"JE Lee","year":"2019","unstructured":"Lee JE, Kim HK (2019) Self-cleanable, waterproof, transparent, and flexible Ag networks covered by hydrophobic polytetrafluoroethylene for multi-functional flexible thin film heaters. Sci Rep 9:16723. https:\/\/doi.org\/10.1038\/s41598-019-53243-w","journal-title":"Sci Rep"},{"key":"5216_CR45","doi-asserted-by":"publisher","first-page":"1418","DOI":"10.1002\/jbm.b.34801","volume":"109","author":"F Sun","year":"2021","unstructured":"Sun F, Hung HC, Yan W, Wu K, Shimchuk AA, Gray SD, He W, Huang X, Zhang H (2021) Inhibition of oral biofilm formation by zwitterionic nonfouling coating. J Biomed Mater Res B Appl Biomater 109:1418\u20131425. https:\/\/doi.org\/10.1002\/jbm.b.34801","journal-title":"J Biomed Mater Res B Appl Biomater"},{"key":"5216_CR46","doi-asserted-by":"publisher","first-page":"17007","DOI":"10.1038\/s41598-021-96622-y","volume":"11","author":"DG Moussa","year":"2021","unstructured":"Moussa DG, Siqueira WL (2021) Bioinspired caries preventive strategy via customizable pellicles of saliva-derived protein\/peptide constructs. Sci Rep 11:17007. https:\/\/doi.org\/10.1038\/s41598-021-96622-y","journal-title":"Sci Rep"},{"key":"5216_CR47","doi-asserted-by":"publisher","first-page":"106128","DOI":"10.1016\/j.ejps.2022.106128","volume":"171","author":"X Chen","year":"2022","unstructured":"Chen X, Zhao S, Chu S, Liu S, Yu M, Li J, Gao F, Liu Y (2022) A novel sustained release fluoride strip based poly(propylene carbonate) for preventing caries. Eur J Pharm Sci 171:106128. https:\/\/doi.org\/10.1016\/j.ejps.2022.106128","journal-title":"Eur J Pharm Sci"},{"key":"5216_CR48","doi-asserted-by":"publisher","first-page":"827643","DOI":"10.3389\/fcimb.2022.827643","volume":"12","author":"C Qi","year":"2022","unstructured":"Qi C, Peng X, Yuan S, Zhang M, Xu X, Cheng X (2022) Evaluation of the antibacterial and anti-inflammatory effects of a natural products-containing toothpaste. Front Cell Infect Microbiol 12:827643. https:\/\/doi.org\/10.3389\/fcimb.2022.827643","journal-title":"Front Cell Infect Microbiol"},{"key":"5216_CR49","doi-asserted-by":"publisher","first-page":"100680","DOI":"10.1016\/j.conctc.2020.100680","volume":"21","author":"PK Sreenivasan","year":"2021","unstructured":"Sreenivasan PK, Haraszthy VI, Rayela CC (2021) Antimicrobial effects in oral microenvironments by a novel herbal toothpaste. Contemp Clin Trials Commun 21:100680. https:\/\/doi.org\/10.1016\/j.conctc.2020.100680","journal-title":"Contemp Clin Trials Commun"},{"key":"5216_CR50","doi-asserted-by":"publisher","first-page":"529","DOI":"10.3290\/j.ohpd.b2182977","volume":"19","author":"NB Arweiler","year":"2021","unstructured":"Arweiler NB, M\u00fcller-Breitenkamp F, Heumann C, Laugisch O, Auschill TM, Action A (2021) Substantivity and anti-plaque effect of different toothpaste slurries - a randomised controlled trial. Oral Health Prev Dent 19:529\u2013536. https:\/\/doi.org\/10.3290\/j.ohpd.b2182977","journal-title":"Oral Health Prev Dent"},{"key":"5216_CR51","doi-asserted-by":"publisher","first-page":"219","DOI":"10.1002\/prot.340160302","volume":"16","author":"L Lebioda","year":"1993","unstructured":"Lebioda L, Zhang E, Lewinski K, Brewer JM (1993) Fluoride inhibition of yeast enolase: crystal structure of the enolase-Mg(2+)-F(-)-Pi complex at 2.6 A resolution. Proteins 16:219\u2013225. https:\/\/doi.org\/10.1002\/prot.340160302","journal-title":"Proteins"},{"key":"5216_CR52","doi-asserted-by":"publisher","first-page":"328","DOI":"10.1111\/j.1399-302x.1990.tb00435.x","volume":"5","author":"EA Thibodeau","year":"1990","unstructured":"Thibodeau EA, Keefe TF (1990) pH-dependent fluoride inhibition of catalase activity. Oral Microbiol Immunol 5:328\u2013331. https:\/\/doi.org\/10.1111\/j.1399-302x.1990.tb00435.x","journal-title":"Oral Microbiol Immunol"},{"key":"5216_CR53","doi-asserted-by":"publisher","first-page":"199","DOI":"10.1016\/0014-5793(93)80169-u","volume":"327","author":"AA Baykov","year":"1993","unstructured":"Baykov AA, Dubnova EB, Bakuleva NP, Evtushenko OA, Zhen RG, Rea PA (1993) Differential sensitivity of membrane-associated pyrophosphatases to inhibition by diphosphonates and fluoride delineates two classes of enzyme. FEBS Lett 327:199\u2013202. https:\/\/doi.org\/10.1016\/0014-5793(93)80169-u","journal-title":"FEBS Lett"},{"key":"5216_CR54","doi-asserted-by":"publisher","first-page":"313","DOI":"10.1111\/j.1399-302x.1991.tb00500.x","volume":"6","author":"EA Thibodeau","year":"1991","unstructured":"Thibodeau EA, Ford CM (1991) Chain formation and de-chaining in Streptococcus sobrinus SL-1. Oral Microbiol Immunol 6:313\u2013315. https:\/\/doi.org\/10.1111\/j.1399-302x.1991.tb00500.x","journal-title":"Oral Microbiol Immunol"},{"key":"5216_CR55","doi-asserted-by":"publisher","first-page":"785","DOI":"10.1139\/m95-108","volume":"41","author":"WA Belli","year":"1995","unstructured":"Belli WA, Buckley DH, Marquis RE (1995) Weak acid effects and fluoride inhibition of glycolysis by Streptococcus mutans GS-5. Can J Microbiol 41:785\u2013791. https:\/\/doi.org\/10.1139\/m95-108","journal-title":"Can J Microbiol"},{"key":"5216_CR56","doi-asserted-by":"publisher","first-page":"741493","DOI":"10.3389\/fmicb.2021.741493","volume":"12","author":"I Ahamad","year":"2021","unstructured":"Ahamad I, Bano F, Anwer R, Srivastava P, Kumar R, Fatma T (2021) Antibiofilm activities of biogenic silver nanoparticles against Candida albicans. Front Microbiol 12:741493. https:\/\/doi.org\/10.3389\/fmicb.2021.741493","journal-title":"Front Microbiol"},{"key":"5216_CR57","doi-asserted-by":"publisher","first-page":"285","DOI":"10.1016\/j.dental.2015.11.015","volume":"32","author":"L Zhang","year":"2016","unstructured":"Zhang L, Weir MD, Chow LC, Antonucci JM, Chen J, Xu HH (2016) Novel rechargeable calcium phosphate dental nanocomposite. Dent Mater 32:285\u2013293. https:\/\/doi.org\/10.1016\/j.dental.2015.11.015","journal-title":"Dent Mater"},{"key":"5216_CR58","doi-asserted-by":"publisher","first-page":"103214","DOI":"10.1016\/j.jdent.2019.103214","volume":"90","author":"J Yi","year":"2019","unstructured":"Yi J, Weir MD, Melo MAS, Li T, Lynch CD, Oates TW, Dai Q, Zhao Z, Xu HHK (2019) Novel rechargeable nano-CaF(2) orthodontic cement with high levels of long-term fluoride release. J Dent 90:103214. https:\/\/doi.org\/10.1016\/j.jdent.2019.103214","journal-title":"J Dent"},{"key":"5216_CR59","doi-asserted-by":"publisher","first-page":"1127","DOI":"10.1016\/j.dental.2018.04.009","volume":"34","author":"NA Al-Eesa","year":"2018","unstructured":"Al-Eesa NA, Johal A, Hill RG, Wong FSL (2018) Fluoride containing bioactive glass composite for orthodontic adhesives - apatite formation properties. Dent Mater 34:1127\u20131133. https:\/\/doi.org\/10.1016\/j.dental.2018.04.009","journal-title":"Dent Mater"},{"key":"5216_CR60","doi-asserted-by":"publisher","first-page":"135","DOI":"10.1016\/j.archoralbio.2019.03.018","volume":"101","author":"T Tanaka","year":"2019","unstructured":"Tanaka T, Kobayashi T, Tamenori Y, Sakanaka A, Kuriki T, Amano A (2019) Phosphoryl oligosaccharides of calcium enhance mineral availability and fluorapatite formation. Arch Oral Biol 101:135\u2013141. https:\/\/doi.org\/10.1016\/j.archoralbio.2019.03.018","journal-title":"Arch Oral Biol"},{"key":"5216_CR61","doi-asserted-by":"publisher","first-page":"6097","DOI":"10.1039\/c2jm16235k","volume":"22","author":"E Jay","year":"2012","unstructured":"Jay E, Rushton M, Grimes R (2012) Migration of fluorine in fluorapatite - a concerted mechanism. J Mater Chem 22:6097\u20136103. https:\/\/doi.org\/10.1039\/c2jm16235k","journal-title":"J Mater Chem"},{"key":"5216_CR62","doi-asserted-by":"publisher","first-page":"2683","DOI":"10.3390\/ma12172683","volume":"12","author":"K Pajor","year":"2019","unstructured":"Pajor K, Pajchel L, Kolmas J (2019) Hydroxyapatite and fluorapatite in conservative dentistry and oral implantology-a review. Materials (Basel) 12:2683. https:\/\/doi.org\/10.3390\/ma12172683","journal-title":"Materials (Basel)"},{"key":"5216_CR63","doi-asserted-by":"publisher","first-page":"45","DOI":"10.1002\/jbm.b.34904","volume":"110","author":"R Ramadoss","year":"2022","unstructured":"Ramadoss R, Padmanaban R, Subramanian B (2022) Role of bioglass in enamel remineralization: existing strategies and future prospects-a narrative review. J Biomed Mater Res B Appl Biomater 110:45\u201366. https:\/\/doi.org\/10.1002\/jbm.b.34904","journal-title":"J Biomed Mater Res B Appl Biomater"},{"key":"5216_CR64","doi-asserted-by":"publisher","first-page":"139","DOI":"10.5005\/jp-journals-10005-1603","volume":"12","author":"MK Arifa","year":"2019","unstructured":"Arifa MK, Ephraim R, Rajamani T (2019) Recent advances in dental hard tissue remineralization: a review of literature. Int J Clin Pediatr Dent 12:139\u2013144. https:\/\/doi.org\/10.5005\/jp-journals-10005-1603","journal-title":"Int J Clin Pediatr Dent"},{"key":"5216_CR65","doi-asserted-by":"publisher","first-page":"157","DOI":"10.2319\/071520-630.1","volume":"91","author":"M Al-Nadawi","year":"2021","unstructured":"Al-Nadawi M, Kravitz ND, Hansa I, Makki L, Ferguson DJ, Vaid NR (2021) Effect of clear aligner wear protocol on the efficacy of tooth movement. Angle Orthod 91:157\u2013163. https:\/\/doi.org\/10.2319\/071520-630.1","journal-title":"Angle Orthod"},{"key":"5216_CR66","doi-asserted-by":"publisher","first-page":"5071","DOI":"10.1007\/s00784-022-04480-3","volume":"26","author":"NAN J\u00fanior","year":"2022","unstructured":"J\u00fanior NAN, Nunes GP, Gruba AS, Danelon M, da Silva L, de Farias Batista G, Briso ALF, Delbem ACB (2022) Evaluation of bleaching efficacy, microhardness, and trans-amelodentinal diffusion of a novel bleaching agent for an in-office technique containing hexametaphosphate and fluoride. Clin Oral Investig 26:5071\u20135078. https:\/\/doi.org\/10.1007\/s00784-022-04480-3","journal-title":"Clin Oral Investig"},{"key":"5216_CR67","doi-asserted-by":"publisher","first-page":"27","DOI":"10.1159\/000342432","volume":"47","author":"B Mohanty","year":"2013","unstructured":"Mohanty B, Dadlani D, Mahoney D, Mann AB (2013) Characterizing and identifying incipient carious lesions in dental enamel using micro-Raman spectroscopy. Caries Res 47:27\u201333. https:\/\/doi.org\/10.1159\/000342432","journal-title":"Caries Res"},{"key":"5216_CR68","doi-asserted-by":"publisher","first-page":"e314","DOI":"10.1016\/j.dental.2021.01.016","volume":"37","author":"Y Xu","year":"2021","unstructured":"Xu Y, Xepapadeas AB, Koos B, Geis-Gerstorfer J, Li P, Spintzyk S (2021) Effect of post-rinsing time on the mechanical strength and cytotoxicity of a 3D printed orthodontic splint material. Dent Mater 37:e314-327. https:\/\/doi.org\/10.1016\/j.dental.2021.01.016","journal-title":"Dent Mater"}],"container-title":["Clinical Oral Investigations"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00784-023-05216-7.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s00784-023-05216-7\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00784-023-05216-7.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,7]],"date-time":"2023-10-07T08:14:37Z","timestamp":1696666477000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s00784-023-05216-7"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,8,24]]},"references-count":68,"journal-issue":{"issue":"10","published-online":{"date-parts":[[2023,10]]}},"alternative-id":["5216"],"URL":"https:\/\/doi.org\/10.1007\/s00784-023-05216-7","relation":{},"ISSN":["1436-3771"],"issn-type":[{"value":"1436-3771","type":"electronic"}],"subject":[],"published":{"date-parts":[[2023,8,24]]},"assertion":[{"value":"27 September 2022","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"14 August 2023","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"24 August 2023","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"The authors declare no competing interests.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of interest"}}]}}