{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,12,10]],"date-time":"2025-12-10T12:37:59Z","timestamp":1765370279233},"reference-count":30,"publisher":"Springer Science and Business Media LLC","issue":"12","license":[{"start":{"date-parts":[[2023,10,17]],"date-time":"2023-10-17T00:00:00Z","timestamp":1697500800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"},{"start":{"date-parts":[[2023,10,17]],"date-time":"2023-10-17T00:00:00Z","timestamp":1697500800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Clin Oral Invest"],"DOI":"10.1007\/s00784-023-05331-5","type":"journal-article","created":{"date-parts":[[2023,10,17]],"date-time":"2023-10-17T16:01:44Z","timestamp":1697558504000},"page":"7417-7423","update-policy":"http:\/\/dx.doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":7,"title":["Evaluation of matrix metalloproteinase-1, -2, -3, -7, and -13 gene polymorphisms in patients with chronic periodontitis and healthy controls"],"prefix":"10.1007","volume":"27","author":[{"given":"Leila","family":"Saremi","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Saharnaz","family":"Esmaeili","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mohammad Ebrahim","family":"Ghaffari","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Soheil","family":"Shahbazi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shirin","family":"Lotfipanah","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mahdi","family":"Kadkhodazadeh","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2023,10,17]]},"reference":[{"issue":"s1","key":"5331_CR1","doi-asserted-by":"publisher","first-page":"S11","DOI":"10.1111\/j.1834-7819.2009.01140.x","volume":"54","author":"J Highfield","year":"2009","unstructured":"Highfield J (2009) Diagnosis and classification of periodontal disease. Aust Dent J 54(s1):S11\u2013S26. https:\/\/doi.org\/10.1111\/j.1834-7819.2009.01140.x","journal-title":"Aust Dent J"},{"issue":"1","key":"5331_CR2","doi-asserted-by":"publisher","first-page":"10","DOI":"10.1111\/j.1600-0757.2011.00413.x","volume":"58","author":"BA Dye","year":"2000","unstructured":"Dye BA (2000) 2012 Global periodontal disease epidemiology. Periodontology 58(1):10\u201325. https:\/\/doi.org\/10.1111\/j.1600-0757.2011.00413.x","journal-title":"Periodontology"},{"issue":"3, Supplement","key":"5331_CR3","doi-asserted-by":"publisher","first-page":"20","DOI":"10.1016\/S1532-3382(12)70006-4","volume":"12","author":"J Otomo-Corgel","year":"2012","unstructured":"Otomo-Corgel J, Pucher JJ, Rethman MP, Reynolds MA (2012) State of the Science: Chronic Periodontitis and Systemic Health. J Evid Based Dent Pract 12(3, Supplement):20\u20138. https:\/\/doi.org\/10.1016\/S1532-3382(12)70006-4","journal-title":"J Evid Based Dent Pract"},{"issue":"8","key":"5331_CR4","doi-asserted-by":"publisher","first-page":"713","DOI":"10.1177\/154405910708600805","volume":"86","author":"DS Brennan","year":"2007","unstructured":"Brennan DS, Spencer AJ, Roberts-Thomson KF (2007) Quality of life and disability weights associated with periodontal disease. J Dent Res 86(8):713\u2013717. https:\/\/doi.org\/10.1177\/154405910708600805","journal-title":"J Dent Res"},{"issue":"6","key":"5331_CR5","doi-asserted-by":"publisher","first-page":"248","DOI":"10.1111\/omi.12065","volume":"29","author":"G Hajishengallis","year":"2014","unstructured":"Hajishengallis G (2014) The inflammophilic character of the periodontitis-associated microbiota. Mol Oral Microbiol 29(6):248\u2013257. https:\/\/doi.org\/10.1111\/omi.12065","journal-title":"Mol Oral Microbiol"},{"issue":"5","key":"5331_CR6","doi-asserted-by":"publisher","first-page":"384","DOI":"10.1111\/j.1600-051X.2007.01071.x","volume":"34","author":"D Chen","year":"2007","unstructured":"Chen D, Wang Q, Ma ZW, Chen FM, Chen Y, Xie GY et al (2007) MMP-2, MMP-9 and TIMP-2 gene polymorphisms in Chinese patients with generalized aggressive periodontitis. J Clin Periodontol 34(5):384\u2013389. https:\/\/doi.org\/10.1111\/j.1600-051X.2007.01071.x","journal-title":"J Clin Periodontol"},{"issue":"8","key":"5331_CR7","doi-asserted-by":"publisher","first-page":"707","DOI":"10.1111\/j.1600-051X.2012.01902.x","volume":"39","author":"A Letra","year":"2012","unstructured":"Letra A, Silva RM, Rylands RJ, Silveira EM, de Souza AP, Wendell SK et al (2012) MMP3 and TIMP1 variants contribute to chronic periodontitis and may be implicated in disease progression. J Clin Periodontol 39(8):707\u2013716. https:\/\/doi.org\/10.1111\/j.1600-051X.2012.01902.x","journal-title":"J Clin Periodontol"},{"issue":"14","key":"5331_CR8","doi-asserted-by":"publisher","first-page":"4923","DOI":"10.3390\/ijerph17144923","volume":"17","author":"V Checchi","year":"2020","unstructured":"Checchi V, Maravic T, Bellini P, Generali L, Consolo U, Breschi L et al (2020) The Role of Matrix Metalloproteinases in Periodontal Disease. Int J Environ Res Public Health 17(14):4923. https:\/\/doi.org\/10.3390\/ijerph17144923","journal-title":"Int J Environ Res Public Health"},{"key":"5331_CR9","doi-asserted-by":"publisher","unstructured":"Kirch W (2008) Single nucleotide polymorphism (SNP). In: Kirch W (eds) Encyclopedia of public health. Springer, Dordrecht. https:\/\/doi.org\/10.1007\/978-1-4020-5614-7_3214","DOI":"10.1007\/978-1-4020-5614-7_3214"},{"issue":"5366","key":"5331_CR10","doi-asserted-by":"publisher","first-page":"1077","DOI":"10.1126\/science.280.5366.1077","volume":"280","author":"DG Wang","year":"1998","unstructured":"Wang DG, Fan JB, Siao CJ, Berno A, Young P, Sapolsky R et al (1998) Large-scale identification, mapping, and genotyping of single-nucleotide polymorphisms in the human genome. Science 280(5366):1077\u20131082. https:\/\/doi.org\/10.1126\/science.280.5366.1077","journal-title":"Science"},{"issue":"6","key":"5331_CR11","doi-asserted-by":"publisher","first-page":"423","DOI":"10.1093\/molehr\/gah177","volume":"11","author":"K Shan","year":"2005","unstructured":"Shan K, Ying W, Jian-Hui Z, Wei G, Na W, Yan L (2005) The function of the SNP in the MMP1 and MMP3 promoter in susceptibility to endometriosis in China. Mol Hum Reprod 11(6):423\u2013427. https:\/\/doi.org\/10.1093\/molehr\/gah177","journal-title":"Mol Hum Reprod"},{"issue":"1","key":"5331_CR12","doi-asserted-by":"publisher","first-page":"157","DOI":"10.1186\/s43042-022-00371-0","volume":"23","author":"L Saremi","year":"2022","unstructured":"Saremi L, Shafizadeh M, Ghaffari ME, Aliniagerdroudbari E, Amid R, Kadkhodazadeh M (2022) Evaluation of interleukin 10, interleukin 1-beta, and tumor necrosis factor-alpha gene polymorphisms in patients with periodontitis and healthy controls. Egypt J Med Hum Genet 23(1):157. https:\/\/doi.org\/10.1186\/s43042-022-00371-0","journal-title":"Egypt J Med Hum Genet"},{"issue":"2","key":"5331_CR13","doi-asserted-by":"publisher","first-page":"156","DOI":"10.3109\/08820139.2012.746697","volume":"42","author":"M Kadkhodazadeh","year":"2013","unstructured":"Kadkhodazadeh M, Baghani Z, Ebadian AR, Youssefi N, Mehdizadeh AR, Azimi N (2013) IL-17 Gene Polymorphism Is Associated with Chronic Periodontitis and Peri-implantitis in Iranian Patients: A Cross-Sectional Study. Immunol Invest 42(2):156\u2013163. https:\/\/doi.org\/10.3109\/08820139.2012.746697","journal-title":"Immunol Invest"},{"key":"5331_CR14","doi-asserted-by":"publisher","DOI":"10.1002\/jcb.28486","author":"L Saremi","year":"2019","unstructured":"Saremi L, Esmaeilzadeh E, Ghorashi T, Sohrabi M, Ekhlasmand Kermani M, Kadkhodazadeh M (2019) Association of Fc gamma-receptor genes polymorphisms with chronic periodontitis and Peri-Implantitis. J Cell Biochem. https:\/\/doi.org\/10.1002\/jcb.28486","journal-title":"J Cell Biochem"},{"issue":"1","key":"5331_CR15","doi-asserted-by":"publisher","first-page":"38","DOI":"10.1111\/j.1399-0039.2006.00615.x","volume":"68","author":"Z Cao","year":"2006","unstructured":"Cao Z, Li C, Zhu G (2006) MMP-1 promoter gene polymorphism and susceptibility to chronic periodontitis in a Chinese population. Tissue Antigens 68(1):38\u201343. https:\/\/doi.org\/10.1111\/j.1399-0039.2006.00615.x","journal-title":"Tissue Antigens"},{"key":"5331_CR16","doi-asserted-by":"publisher","unstructured":"Majumder P, Ghosh S, Dey SK (2019) Matrix metalloproteinase gene polymorphisms in chronic periodontitis: a case-control study in the Indian population. J Genet 98(1):32. https:\/\/doi.org\/10.1007\/s12041-019-1077-2","DOI":"10.1007\/s12041-019-1077-2"},{"key":"5331_CR17","doi-asserted-by":"publisher","first-page":"237","DOI":"10.1515\/med-2018-0037","volume":"13","author":"M Kobusiak-Prokopowicz","year":"2018","unstructured":"Kobusiak-Prokopowicz M, Krzysztofik J, Kaaz K, Jolda-Mydlowska B, Mysiak A (2018) MMP-2 and TIMP-2 in Patients with Heart Failure and Chronic Kidney Disease. Open Med (Wars) 13:237\u2013246. https:\/\/doi.org\/10.1515\/med-2018-0037","journal-title":"Open Med (Wars)"},{"issue":"1","key":"5331_CR18","doi-asserted-by":"publisher","first-page":"13","DOI":"10.1006\/exnr.2002.8019","volume":"178","author":"S Lorenzl","year":"2002","unstructured":"Lorenzl S, Albers DS, Narr S, Chirichigno J, Beal MF (2002) Expression of MMP-2, MMP-9, and MMP-1 and Their Endogenous Counterregulators TIMP-1 and TIMP-2 in Postmortem Brain Tissue of Parkinson\u2019s Disease. Exp Neurol 178(1):13\u201320. https:\/\/doi.org\/10.1006\/exnr.2002.8019","journal-title":"Exp Neurol"},{"issue":"20","key":"5331_CR19","doi-asserted-by":"publisher","first-page":"2191","DOI":"10.1001\/jama.2013.281053","volume":"310","author":"World Medical Association Declaration of Helsinki","year":"2013","unstructured":"World Medical Association Declaration of Helsinki (2013) ethical principles for medical research involving human subjects. JAMA 310(20):2191\u20132194. https:\/\/doi.org\/10.1001\/jama.2013.281053","journal-title":"JAMA"},{"issue":"7624","key":"5331_CR20","doi-asserted-by":"publisher","first-page":"806","DOI":"10.1136\/bmj.39335.541782.AD","volume":"335","author":"E von Elm","year":"2007","unstructured":"von Elm E, Altman DG, Egger M, Pocock SJ, G\u00f8tzsche PC, Vandenbroucke JP (2007) Strengthening the Reporting of Observational Studies in Epidemiology (STROBE) statement: guidelines for reporting observational studies. BMJ 335(7624):806\u2013808. https:\/\/doi.org\/10.1136\/bmj.39335.541782.AD","journal-title":"BMJ"},{"key":"5331_CR21","doi-asserted-by":"publisher","unstructured":"Vahabi S, Nazemisalman B, Kalantari M, Hosseinpour S (2019) Association of matrix metalloproteinase-1 -1607 1G\/2G and C-Reactive Protein -717 C\/T gene polymorphisms in Iranian patients with chronic periodontitis: a clinical trial. Iran Red Crescent Med J 21(1).\u00a0https:\/\/doi.org\/10.5812\/ircmj.84396","DOI":"10.5812\/ircmj.84396"},{"issue":"2","key":"5331_CR22","doi-asserted-by":"publisher","first-page":"552","DOI":"10.1016\/j.cyto.2012.06.239","volume":"60","author":"G Li","year":"2012","unstructured":"Li G, Yue Y, Tian Y, Li JL, Wang M, Liang H et al (2012) Association of matrix metalloproteinase (MMP)-1, 3, 9, interleukin (IL)-2, 8 and cyclooxygenase (COX)-2 gene polymorphisms with chronic periodontitis in a Chinese population. Cytokine 60(2):552\u2013560. https:\/\/doi.org\/10.1016\/j.cyto.2012.06.239","journal-title":"Cytokine"},{"issue":"10","key":"5331_CR23","doi-asserted-by":"publisher","first-page":"1260","DOI":"10.3390\/pathogens10101260","volume":"10","author":"G Kasnak","year":"2021","unstructured":"Kasnak G, Y\u0131lmaz M, \u00dcnsal RBK, Polat NG, F\u0131ratl\u0131 E (2021) Evaluation of Gene Polymorphism and Gingival Crevicular Fluid Levels of Matrix Metalloproteinase-3 in a Group of Turkish Periodontitis Patients. Pathogens 10(10):1260. https:\/\/doi.org\/10.3390\/pathogens10101260","journal-title":"Pathogens"},{"issue":"10","key":"5331_CR24","doi-asserted-by":"publisher","first-page":"699","DOI":"10.1111\/j.1600-051X.2006.00979.x","volume":"33","author":"CM Astolfi","year":"2006","unstructured":"Astolfi CM, Shinohara AL, da Silva RA, Santos MC, Line SR, de Souza AP (2006) Genetic polymorphisms in the MMP-1 and MMP-3 gene may contribute to chronic periodontitis in a Brazilian population. J Clin Periodontol 33(10):699\u2013703. https:\/\/doi.org\/10.1111\/j.1600-051X.2006.00979.x","journal-title":"J Clin Periodontol"},{"issue":"6","key":"5331_CR25","doi-asserted-by":"publisher","first-page":"474","DOI":"10.4103\/jisp.jisp_333_18","volume":"22","author":"JS Prasanna","year":"2018","unstructured":"Prasanna JS, Aishwarya MD, Karunakar P, Rekharani K, Vijayalakshmi B, Jharna P (2018) Evaluation of collagenase-3 matrix metalloproteinase-13 gene-associated polymorphisms 11A\/12A and -77A\/G and its associated alleles with and without periodontitis. J Indian Soc Periodontol 22(6):474\u2013479. https:\/\/doi.org\/10.4103\/jisp.jisp_333_18","journal-title":"J Indian Soc Periodontol"},{"issue":"2","key":"5331_CR26","doi-asserted-by":"publisher","first-page":"128","DOI":"10.1590\/0103-6440201600601","volume":"27","author":"R Gon\u00e7alves Junior","year":"2016","unstructured":"Gon\u00e7alves Junior R, Pinheiro AA, Schoichet JJ, Nunes CH, Gon\u00e7alves R, Bonato LL et al (2016) MMP13, TIMP2 and TGFB3 Gene Polymorphisms in Brazilian Chronic Periodontitis and Periimplantitis Subjects. Braz Dent J 27(2):128\u201334. https:\/\/doi.org\/10.1590\/0103-6440201600601","journal-title":"Braz Dent J"},{"issue":"1","key":"5331_CR27","doi-asserted-by":"publisher","first-page":"102","DOI":"10.1111\/j.1600-0757.2010.00371.x","volume":"56","author":"J Zhang","year":"2000","unstructured":"Zhang J, Sun X, Xiao L, Xie C, Xuan D (2000) Luo G 2011 Gene polymorphisms and periodontitis. Periodontol 56(1):102\u201324. https:\/\/doi.org\/10.1111\/j.1600-0757.2010.00371.x","journal-title":"Periodontol"},{"issue":"3","key":"5331_CR28","doi-asserted-by":"publisher","first-page":"1806","DOI":"10.3390\/ijms23031806","volume":"23","author":"I Luchian","year":"2022","unstructured":"Luchian I, Goriuc A, Sandu D, Covasa M (2022) The Role of Matrix Metalloproteinases (MMP-8, MMP-9, MMP-13) in Periodontal and Peri-Implant Pathological Processes. Int J Mol Sci 23(3):1806. https:\/\/doi.org\/10.3390\/ijms23031806","journal-title":"Int J Mol Sci"},{"issue":"1","key":"5331_CR29","doi-asserted-by":"publisher","first-page":"29","DOI":"10.1111\/prd.12027","volume":"63","author":"M Barczyk","year":"2000","unstructured":"Barczyk M, Bolstad AI, Gullberg D (2000) 2013 Role of integrins in the periodontal ligament: organizers and facilitators. Periodontology 63(1):29\u201347. https:\/\/doi.org\/10.1111\/prd.12027","journal-title":"Periodontology"},{"issue":"4","key":"5331_CR30","doi-asserted-by":"publisher","first-page":"411","DOI":"10.1016\/j.jds.2016.07.001","volume":"11","author":"YF Hsiao","year":"2016","unstructured":"Hsiao YF, Yang LC, Chou YS, Ho YP, Lin YC, Ho KY et al (2016) Matrix metalloproteinase-2, -9, and tissue inhibitor of MMP-2 gene polymorphisms in Taiwanese periodontitis patients. J Dent Sci 11(4):411\u2013418. https:\/\/doi.org\/10.1016\/j.jds.2016.07.001","journal-title":"J Dent Sci"}],"container-title":["Clinical Oral Investigations"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00784-023-05331-5.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s00784-023-05331-5\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00784-023-05331-5.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,12,12]],"date-time":"2023-12-12T04:33:41Z","timestamp":1702355621000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s00784-023-05331-5"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,10,17]]},"references-count":30,"journal-issue":{"issue":"12","published-online":{"date-parts":[[2023,12]]}},"alternative-id":["5331"],"URL":"https:\/\/doi.org\/10.1007\/s00784-023-05331-5","relation":{},"ISSN":["1436-3771"],"issn-type":[{"value":"1436-3771","type":"electronic"}],"subject":[],"published":{"date-parts":[[2023,10,17]]},"assertion":[{"value":"30 June 2023","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"10 October 2023","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"17 October 2023","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"The authors declare no competing interests.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}},{"value":"Following the local ethics committee approval (DRC.REC.1399.099), written consent forms were signed by the patients.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethics approval and consent to participate"}},{"value":"The authors declare that they have no conflict of interest.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of interest"}}]}}