{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,12]],"date-time":"2026-09-12T06:27:10Z","timestamp":1789194430753,"version":"build-2803163510"},"reference-count":17,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2024,1,25]],"date-time":"2024-01-25T00:00:00Z","timestamp":1706140800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"},{"start":{"date-parts":[[2024,1,25]],"date-time":"2024-01-25T00:00:00Z","timestamp":1706140800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"}],"funder":[{"DOI":"10.13039\/100007797","name":"University of Helsinki","doi-asserted-by":"crossref","id":[{"id":"10.13039\/100007797","id-type":"DOI","asserted-by":"crossref"}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Clin Oral Invest"],"abstract":"<jats:title>Abstract<\/jats:title><jats:sec>\n                <jats:title>Objectives<\/jats:title>\n                <jats:p>The primary aim of the present study was to compare head and neck cancer treatment modality surgery and surgery with radiotherapy or chemoradiotherapy alone for dental implant (DI) survival. The second aim was to evaluate the prevalence of mucosal overgrowth around DI after treatment with or without mucosal grafts.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Materials and methods<\/jats:title>\n                <jats:p>An observational retrospective study consisted of 59 patients with malignant head and neck tumors that received DI between 2015 and 2019. Treatment modalities together with information on oral rehabilitation with DI, prevalence of mucosal overgrowth, and precursor lesions were gathered from the hospital records. Radiation doses were determined using a sum of three-dimensional dose distributions.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Results<\/jats:title>\n                <jats:p>Overall DI survival rate was 88%, in irritated jaw 89%, and in nonirradiated jaw 88% in this observational period (<jats:italic>p<\/jats:italic>\u2009=\u20090.415, mean follow-up was 2\u00a0years 10\u00a0months, range 9\u201382\u00a0months). Mucosal overgrowth was found in 42 of 196 implants (21%), of which 36 cases (86%) were associated in grafted areas (<jats:italic>p<\/jats:italic>\u2009&lt;\u20090.001). Oral lichen planus\/lichenoid reaction was diagnosed in 14 of all 59 (24%) oral cancer patients.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Conclusion<\/jats:title>\n                <jats:p>Implant survival was not significantly influenced by radiation therapy in this observational period. In grafted bone, implant survival was significantly inferior than in native bone. Mucosal overgrowth around implants was more common in mucosal grafted areas versus nongrafted.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Clinical relevance<\/jats:title>\n                <jats:p>This study demonstrates the impact of grafted bone to dental implant survival rate and mucosal overgrowth.<\/jats:p>\n              <\/jats:sec>","DOI":"10.1007\/s00784-023-05479-0","type":"journal-article","created":{"date-parts":[[2024,1,25]],"date-time":"2024-01-25T17:34:32Z","timestamp":1706204072000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":4,"title":["Survival of dental implants and occurrence of mucosal overgrowth in patients with head and neck cancer treated with\/without radiotherapy and mucosal graft\u2014two-year follow-up"],"prefix":"10.1007","volume":"28","author":[{"given":"Viivi","family":"Mattila","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tommy","family":"Wilkman","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nina-Li","family":"Avell\u00e1n","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Karri","family":"Mesim\u00e4ki","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jussi","family":"Furuholm","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hellevi","family":"Ruokonen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Karita","family":"Nylund","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2024,1,25]]},"reference":[{"key":"5479_CR1","doi-asserted-by":"publisher","first-page":"104799","DOI":"10.1016\/j.oraloncology.2020.104799","volume":"107","author":"A Almangush","year":"2020","unstructured":"Almangush A, M\u00e4kitie AA, Triantafyllou A, de Bree R, Strojan P, Rinaldo A, Hernandez-Prera JC, Su\u00e1rez C, Kowalski LP, Ferlito A, Leivo I (2020) Staging and grading of oral squamous cell carcinoma: an update. 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Clin Implant Dent Relat Res 14(6):839\u2013851. https:\/\/doi.org\/10.1111\/j.1708-8208.2012.00456.x","journal-title":"Clin Implant Dent Relat Res"},{"issue":"2","key":"5479_CR4","doi-asserted-by":"publisher","first-page":"372","DOI":"10.1111\/cid.12457","volume":"19","author":"R Doornewaard","year":"2017","unstructured":"Doornewaard R, Christiaens V, De Bruyn H, Jacobsson M, Cosyn J, Vervaeke S, Jacquet W (2017) Long-term effect of surface roughness and patients\u2019 factors on crestal bone loss at dental implants. a systematic review and meta-analysis. 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No ethics approval is needed.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethics approval and consent to participate"}}],"article-number":"117"}}