{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,11]],"date-time":"2026-07-11T21:01:27Z","timestamp":1783803687911,"version":"3.55.0"},"reference-count":41,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2024,1,20]],"date-time":"2024-01-20T00:00:00Z","timestamp":1705708800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"},{"start":{"date-parts":[[2024,1,20]],"date-time":"2024-01-20T00:00:00Z","timestamp":1705708800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"}],"funder":[{"DOI":"10.13039\/501100005378","name":"Hacettepe University","doi-asserted-by":"crossref","id":[{"id":"10.13039\/501100005378","id-type":"DOI","asserted-by":"crossref"}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Clin Oral Invest"],"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Objectives<\/jats:title><jats:p>The study aimed to evaluate the impact of molar incisor hypomineralization (MIH) and tooth sensitivity on the oral health in terms of the quality of life (OHRQoL). In addition, the impact of tooth maturity on tooth sensitivity was evaluated in the study.<\/jats:p><\/jats:sec><jats:sec><jats:title>Materials and methods<\/jats:title><jats:p>Children aged 8\u201312 years with and without MIH participated in this descriptive cross-sectional study. They were chosen through the convenience sample technique. The<jats:italic>Pediatric-Oral-Health-related-Quality-of-Life (POQL)<\/jats:italic>scale was used to assess OHRQoL. The presence of the MIH and decayed, filled and missing teeth due to caries (<jats:italic>using dmft\/s, DMFT\/S indexes<\/jats:italic>) were recorded. The tooth sensitivity and dental maturity status were evaluated with the<jats:italic>Shiff-Cold-Air-Sensitivity-Scale (SCASS)<\/jats:italic>and<jats:italic>Demirjian-method<\/jats:italic>, respectively. Statistical analysis of the data was performed by Pearson Chi-Square Test and Mann-Whitney<jats:italic>U<\/jats:italic>test (<jats:italic>p<\/jats:italic>&lt;0.05).<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>In this study, the participants were a total of 260 children, half were affected by the MIH. Their mean POQL scores were higher than those of the children without MIH with a statistically significantly difference in the total child scale score (<jats:italic>p<\/jats:italic>=0.014). Among the children with the MIH, child total QoL score was found to be higher in SCASS positive response group (<jats:italic>p<\/jats:italic>=0.011). The teeth with MIH (<jats:italic>p<\/jats:italic>&lt;0.001) showed higher response to the stimulus. According to the dental age and dental maturity categories of the children with MIH, the total child scale score was found to be higher in the SCASS category (<jats:italic>p<\/jats:italic>=0.011), and the response status to the SCASS was statistically significant (<jats:italic>p<\/jats:italic>=0.042 and<jats:italic>p<\/jats:italic>=0.05, respectively).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Among the children with MIH, the OHRQoL was found to be negatively affected. The teeth with the MIH tend to reveal more tooth sensitivity than healthy teeth. Many conditions such as having MIH, and tooth sensitivity might have an impact on the OHRQoL. In addition, more sensitivity to the stimulus was observed in the teeth with lower tooth maturity status; the dental age and dental maturity might have effects on tooth sensitivity.<\/jats:p><\/jats:sec><jats:sec><jats:title>Clinical relevance<\/jats:title><jats:p>Considering the negative impacts due to MIH, the evaluation of OHRQoL is critical for dentists to employ a well-defined guide in their clinical decisions.<\/jats:p><\/jats:sec>","DOI":"10.1007\/s00784-024-05490-z","type":"journal-article","created":{"date-parts":[[2024,1,20]],"date-time":"2024-01-20T09:02:16Z","timestamp":1705741336000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":22,"title":["Molar incisor hypomineralization and oral health-related quality of life: a sample of 8\u201312-years-old children"],"prefix":"10.1007","volume":"28","author":[{"given":"Seyma","family":"Kisacik","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Cansu Ozsin","family":"Ozler","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Seval","family":"Olmez","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2024,1,20]]},"reference":[{"issue":"5","key":"5490_CR1","doi-asserted-by":"publisher","first-page":"390","DOI":"10.1159\/000047479","volume":"35","author":"KL Weerheijm","year":"2001","unstructured":"Weerheijm KL, J\u00e4levik B, Alaluusua S (2001) Molar-incisor hypomineralisation. Caries Res 35(5):390\u2013391","journal-title":"Caries Res"},{"key":"5490_CR2","doi-asserted-by":"crossref","unstructured":"Wright JT (2015) Diagnosis and treatment of molar-incisor hypomineralization. In: Handbook Clin Techniques Pediatr Dent, pp 99\u2013106","DOI":"10.1002\/9781118998199.ch12"},{"issue":"3","key":"5490_CR3","first-page":"114","volume":"4","author":"KL Weerheijm","year":"2003","unstructured":"Weerheijm KL (2003) Molar incisor hypomineralisation (MIH). Eur J Paediatr Dent 4(3):114\u2013120","journal-title":"Eur J Paediatr Dent"},{"issue":"1","key":"5490_CR4","doi-asserted-by":"publisher","first-page":"9","DOI":"10.12968\/denu.2004.31.1.9","volume":"31","author":"KL Weerheijm","year":"2004","unstructured":"Weerheijm KL (2004) Molar incisor hypomineralization (MIH): clinical presentation, aetiology and management. Dent Update 31(1):9\u201312","journal-title":"Dent Update"},{"issue":"7","key":"5490_CR5","doi-asserted-by":"publisher","first-page":"2311","DOI":"10.1007\/s00784-016-2024-8","volume":"21","author":"K Bekes","year":"2017","unstructured":"Bekes K, Heinzelmann K, Lettner S, Schaller HG (2017) Efficacy of desensitizing products containing 8% arginine and calcium carbonate for hypersensitivity relief in MIH-affected molars: an 8-week clinical study. Clin Oral Investig 21(7):2311\u20132317","journal-title":"Clin Oral Investig"},{"key":"5490_CR6","doi-asserted-by":"publisher","first-page":"37","DOI":"10.1186\/s12903-015-0017-7","volume":"15","author":"TA Oyedele","year":"2015","unstructured":"Oyedele TA, Folayan MO, Adekoya-Sofowora CA, Oziegbe EO (2015) Co-morbidities associated with molar-incisor hypomineralisation in 8 to 16 year old pupils in Ile-Ife, Nigeria. BMC Oral Health 15:37","journal-title":"BMC Oral Health"},{"issue":"1","key":"5490_CR7","doi-asserted-by":"publisher","first-page":"17922","DOI":"10.1038\/s41598-021-95875-x","volume":"11","author":"T Linner","year":"2021","unstructured":"Linner T, Khazaei Y, B\u00fccher K, Pfisterer J, Hickel R, K\u00fchnisch J (2021) Hypersensitivity in teeth affected by molar-incisor hypomineralization (MIH). Sci Rep 11(1):17922","journal-title":"Sci Rep"},{"key":"5490_CR8","volume-title":"Molar incisor hypomineralization","author":"K Bekes","year":"2022","unstructured":"Bekes K (2022) Molar incisor hypomineralization. Springer"},{"issue":"1","key":"5490_CR9","doi-asserted-by":"publisher","first-page":"e117","DOI":"10.1590\/1807-3107BOR-2016.vol30.0117","volume":"30","author":"NB Dantas-Neta","year":"2016","unstructured":"Dantas-Neta NB, Moura LF, Cruz PF, Moura MS, Paiva SM, Martins CC et al (2016) Impact of molar-incisor hypomineralization on oral health-related quality of life in schoolchildren. Braz Oral Res 30(1):e117","journal-title":"Braz Oral Res"},{"issue":"2","key":"5490_CR10","doi-asserted-by":"publisher","first-page":"273","DOI":"10.1007\/s40368-020-00556-4","volume":"22","author":"F Dias","year":"2021","unstructured":"Dias F, Gradella CMF, Ferreira MC, Oliveira LB (2021) Molar-incisor hypomineralization: parent's and children's impact perceptions on the oral health-related quality of life. Eur Arch Paediatr Dent 22(2):273\u2013282","journal-title":"Eur Arch Paediatr Dent"},{"issue":"1","key":"5490_CR11","doi-asserted-by":"publisher","first-page":"65","DOI":"10.1007\/s40368-021-00631-4","volume":"23","author":"B J\u00e4levik","year":"2022","unstructured":"J\u00e4levik B, Sabel N, Robertson A (2022) Can molar incisor hypomineralization cause dental fear and anxiety or influence the oral health-related quality of life in children and adolescents?-a systematic review. Eur Arch Paediatr Dent 23(1):65\u201378","journal-title":"Eur Arch Paediatr Dent"},{"issue":"2","key":"5490_CR12","doi-asserted-by":"publisher","first-page":"1753","DOI":"10.1007\/s00784-021-04150-w","volume":"26","author":"T Joshi","year":"2022","unstructured":"Joshi T, Rahman A, Rienhoff S, Rienhoff J, Stamm T, Bekes K (2022) Impact of molar incisor hypomineralization on oral health-related quality of life in 8-10-year-old children. Clin Oral Investig 26(2):1753\u20131759","journal-title":"Clin Oral Investig"},{"key":"5490_CR13","doi-asserted-by":"crossref","unstructured":"Amrollahi N, Hashemi S, Heidari Z (2023) Impact of molar incisor hypomineralization on oral health-related quality of life in 8-10 years old children: a systematic review and meta-analysis. J Evid-Based Dent Pract 23(3):101889","DOI":"10.1016\/j.jebdp.2023.101889"},{"issue":"4","key":"5490_CR14","doi-asserted-by":"crossref","first-page":"368","DOI":"10.4103\/jisppd.jisppd_27_23","volume":"40","author":"AM Jawdekar","year":"2022","unstructured":"Jawdekar AM, Kamath S, Kale S, Mistry L (2022) Assessment of oral health-related quality of life (OHRQoL) in children with molar incisor hypomineralization (MIH)\u2013a systematic review and meta-analysis of observational studies. J Indian Soc Pedod Prev Dent 40(4):368\u2013376","journal-title":"J Indian Soc Pedod Prev Dent"},{"issue":"1","key":"5490_CR15","doi-asserted-by":"publisher","first-page":"33","DOI":"10.1002\/cre2.245","volume":"6","author":"J F\u00fctterer","year":"2020","unstructured":"F\u00fctterer J, Ebel M, Bekes K, Klode C, Hirsch C (2020) Influence of customized therapy for molar incisor hypomineralization on children's oral hygiene and quality of life. Clin Exp Dent Res 6(1):33\u201343","journal-title":"Clin Exp Dent Res"},{"issue":"3","key":"5490_CR16","first-page":"224","volume":"28","author":"V William","year":"2006","unstructured":"William V, Messer LB, Burrow MF (2006) Molar incisor hypomineralization: review and recommendations for clinical management. Pediatr Dent 28(3):224\u2013232","journal-title":"Pediatr Dent"},{"issue":"3","key":"5490_CR17","first-page":"185","volume":"71","author":"NL Huntington","year":"2011","unstructured":"Huntington NL, Spetter D, Jones JA, Rich SE, Garcia RI, Spiro A 3rd. (2011) Development and validation of a measure of pediatric oral health-related quality of life: the POQL. J Public Health Dent 71(3):185\u2013193","journal-title":"J Public Health Dent"},{"issue":"1","key":"5490_CR18","doi-asserted-by":"publisher","first-page":"25","DOI":"10.26650\/eor.2018.53923","volume":"52","author":"\u0130 Yazicio\u011flu","year":"2018","unstructured":"Yazicio\u011flu \u0130, Jones J, Do\u011fan C, Sharon R, Garcia RI (2018) Validity and reliability of a Turkish pediatric oral health-related quality of life measure. Eur Oral Res 52(1):25\u201332","journal-title":"Eur Oral Res"},{"key":"5490_CR19","volume-title":"Oral health surveys: basic methods","author":"Organization WH","year":"2013","unstructured":"Organization WH (2013) Oral health surveys: basic methods. World Health Organization"},{"issue":"3","key":"5490_CR20","first-page":"110","volume":"4","author":"KL Weerheijm","year":"2003","unstructured":"Weerheijm KL, Duggal M, Mej\u00e0re I, Papagiannoulis L, Koch G, Martens LC et al (2003) Judgement criteria for molar incisor hypomineralisation (MIH) in epidemiologic studies: a summary of the European meeting on MIH held in Athens, 2003. Eur J Paediatr Dent 4(3):110\u2013113","journal-title":"Eur J Paediatr Dent"},{"issue":"3","key":"5490_CR21","doi-asserted-by":"publisher","first-page":"235","DOI":"10.1007\/s40368-015-0178-8","volume":"16","author":"A Ghanim","year":"2015","unstructured":"Ghanim A, Elfrink M, Weerheijm K, Mari\u00f1o R, Manton D (2015) A practical method for use in epidemiological studies on enamel hypomineralisation. Eur Arch Paediatr Dent 16(3):235\u2013246","journal-title":"Eur Arch Paediatr Dent"},{"issue":"2","key":"5490_CR22","doi-asserted-by":"publisher","first-page":"75","DOI":"10.1007\/BF03262716","volume":"11","author":"NA Lygidakis","year":"2010","unstructured":"Lygidakis NA, Wong F, J\u00e4levik B, Vierrou AM, Alaluusua S, Espelid I (2010) Best clinical practice guidance for clinicians dealing with children presenting with molar-incisor-hypomineralisation (MIH): An EAPD Policy Document. Eur Arch Paediatr Dent 11(2):75\u201381","journal-title":"Eur Arch Paediatr Dent"},{"key":"5490_CR23","doi-asserted-by":"publisher","first-page":"225","DOI":"10.1007\/s40368-017-0293-9","volume":"18","author":"A Ghanim","year":"2017","unstructured":"Ghanim A, Silva M, Elfrink M, Lygidakis N, Mari\u00f1o R, Weerheijm K et al (2017) Molar incisor hypomineralisation (MIH) training manual for clinical field surveys and practice. Eur Arch Paediatr Dent 18:225\u2013242","journal-title":"Eur Arch Paediatr Dent"},{"key":"5490_CR24","first-page":"87","volume":"5","author":"T Schiff","year":"1994","unstructured":"Schiff T, Dotson M, Cohen S, De Vizio W, McCool J, Volpe A (1994) Efficacy of a dentifrice containing potassium nitrate, soluble pyrophosphate, PVM\/MA copolymer, and sodium fluoride on dentinal hypersensitivity: a twelve-week clinical study. J Clin Dent 5:87\u201392","journal-title":"J Clin Dent"},{"key":"5490_CR25","unstructured":"Demirjian A, Goldstein H, Tanner JM (1973) A new system of dental age assessment. Hum Biol 45:211\u201327"},{"issue":"6","key":"5490_CR26","doi-asserted-by":"publisher","first-page":"619","DOI":"10.1016\/j.jdent.2015.03.011","volume":"43","author":"F Vargas-Ferreira","year":"2015","unstructured":"Vargas-Ferreira F, Salas MM, Nascimento GG, Tarquinio SB, Faggion CM Jr, Peres MA et al (2015) Association between developmental defects of enamel and dental caries: a systematic review and meta-analysis. J Dent 43(6):619\u2013628","journal-title":"J Dent"},{"issue":"11","key":"5490_CR27","doi-asserted-by":"publisher","first-page":"3971","DOI":"10.1007\/s00784-020-03263-y","volume":"24","author":"AL Fatturi","year":"2020","unstructured":"Fatturi AL, Menoncin BL, Reyes MT, Meger M, Scariot R, Brancher JA et al (2020) The relationship between molar incisor hypomineralization, dental caries, socioeconomic factors, and polymorphisms in the vitamin D receptor gene: a population-based study. Clin Oral Investig 24(11):3971\u20133980","journal-title":"Clin Oral Investig"},{"issue":"1","key":"5490_CR28","doi-asserted-by":"publisher","first-page":"11","DOI":"10.1111\/ipd.12233","volume":"27","author":"GC Americano","year":"2017","unstructured":"Americano GC, Jacobsen PE, Soviero VM, Haubek D (2017) A systematic review on the association between molar incisor hypomineralization and dental caries. Int J Paediatr Dent 27(1):11\u201321","journal-title":"Int J Paediatr Dent"},{"issue":"2","key":"5490_CR29","doi-asserted-by":"publisher","first-page":"170","DOI":"10.1111\/ipd.12323","volume":"28","author":"D Zhao","year":"2018","unstructured":"Zhao D, Dong B, Yu D, Ren Q, Sun Y (2018) The prevalence of molar incisor hypomineralization: evidence from 70 studies. Int J Paediatr Dent 28(2):170\u2013179","journal-title":"Int J Paediatr Dent"},{"issue":"1","key":"5490_CR30","first-page":"38","volume":"31","author":"LM Velandia","year":"2018","unstructured":"Velandia LM, \u00c1lvarez LV, Mej\u00eda LP, Rodr\u00edguez MJ (2018) Oral health-related quality of life in Colombian children with molar-incisor hypomineralization. Acta Odontol Latinoam 31(1):38\u201344","journal-title":"Acta Odontol Latinoam"},{"issue":"4","key":"5490_CR31","doi-asserted-by":"publisher","first-page":"496","DOI":"10.1111\/ipd.12482","volume":"29","author":"PD Portella","year":"2019","unstructured":"Portella PD, Menoncin BLV, de Souza JF, de Menezes J, Fraiz FC, Assun\u00e7\u00e3o L (2019) Impact of molar incisor hypomineralization on quality of life in children with early mixed dentition: a hierarchical approach. Int J Paediatr Dent 29(4):496\u2013506","journal-title":"Int J Paediatr Dent"},{"issue":"2","key":"5490_CR32","doi-asserted-by":"publisher","first-page":"229","DOI":"10.1111\/hae.13678","volume":"25","author":"I Yazicioglu","year":"2019","unstructured":"Yazicioglu I, Deveci C, \u00c7ift\u00e7i V, Antmen B, Do\u011fan MC (2019) Parent\u2019s report on oral health-related quality of life of children with haemophilia. Haemophilia 25(2):229\u2013235","journal-title":"Haemophilia"},{"issue":"2","key":"5490_CR33","first-page":"689","volume":"13","author":"N Haliti","year":"2020","unstructured":"Haliti N, Shabani R, Mrasori S, Dragidella F, Juric H, Behrami NS et al (2020) Teeth and soft tissue injuries as well as wound healing quality patterns among primary school students of Prishtina Region. J Int Dent Med Res 13(2):689\u2013696","journal-title":"J Int Dent Med Res"},{"issue":"3","key":"5490_CR34","first-page":"223","volume":"43","author":"CL Randall","year":"2021","unstructured":"Randall CL, Wallace E, Heaton LJ, Christiansen M, Kim A, Seminario AL et al (2021) Longitudinal analysis of children's oral health-related quality of life after restorative dental treatment. Pediatr Dent 43(3):223\u2013229","journal-title":"Pediatr Dent"},{"issue":"4","key":"5490_CR35","first-page":"3","volume":"31","author":"S G\u00f6kalp","year":"2007","unstructured":"G\u00f6kalp S, Do\u011fan GB, Tek\u00e7i\u00e7ek M, Berbero\u011flu A, \u00dcnl\u00fcer \u015e (2007) Be\u015f, on iki ve on be\u015f ya\u015f \u00e7ocuklar\u0131n a\u011f\u0131z di\u015f sa\u011fl\u0131\u011f\u0131 profili, T\u00fcrkiye-2004. Hacettepe Di\u015fhekimli\u011fi Fak\u00fcltesi Derg(Clinical Dentistry and Research) 31(4):3\u201310","journal-title":"Hacettepe Di\u015fhekimli\u011fi Fak\u00fcltesi Derg(Clinical Dentistry and Research)"},{"issue":"6","key":"5490_CR36","doi-asserted-by":"publisher","first-page":"531","DOI":"10.1590\/S1806-83242011000600010","volume":"25","author":"F Vargas-Ferreira","year":"2011","unstructured":"Vargas-Ferreira F, Ardenghi TM (2011) Developmental enamel defects and their impact on child oral health-related quality of life. Braz Oral Res 25(6):531\u2013537","journal-title":"Braz Oral Res"},{"issue":"5","key":"5490_CR37","doi-asserted-by":"publisher","first-page":"372","DOI":"10.1111\/ipd.12271","volume":"27","author":"SC Leal","year":"2017","unstructured":"Leal SC, Oliveira TRM, Ribeiro APD (2017) Do parents and children perceive molar-incisor hypomineralization as an oral health problem? Int J Paediatr Dent 27(5):372\u2013379","journal-title":"Int J Paediatr Dent"},{"issue":"3","key":"5490_CR38","first-page":"183","volume":"30","author":"P Arrow","year":"2013","unstructured":"Arrow P (2013) Child oral health-related quality of life (COHQoL), enamel defects of the first permanent molars and caries experience among children in Western Australia. Commun Dent Health 30(3):183\u2013188","journal-title":"Commun Dent Health"},{"issue":"4","key":"5490_CR39","doi-asserted-by":"publisher","first-page":"424","DOI":"10.1159\/000495848","volume":"53","author":"F Raposo","year":"2019","unstructured":"Raposo F, de Carvalho Rodrigues AC, Lia \u00c9N, Leal SC (2019) Prevalence of hypersensitivity in teeth affected by molar-incisor hypomineralization (MIH). Caries Res 53(4):424\u2013430","journal-title":"Caries Res"},{"issue":"3","key":"5490_CR40","first-page":"218","volume":"43","author":"CRN de Castro","year":"2021","unstructured":"de Castro CRN, Lima CCB, Costa LC, Silva RNC, Pascotto RC, de Moura MS et al (2021) Hypomineralized teeth have a higher frequency of dental hypersensitivity. Pediatr Dent 43(3):218\u2013222","journal-title":"Pediatr Dent"},{"issue":"5","key":"5490_CR41","doi-asserted-by":"publisher","first-page":"4071","DOI":"10.1007\/s00784-022-04375-3","volume":"26","author":"K Elhennawy","year":"2022","unstructured":"Elhennawy K, Rajjoub O, Reissmann DR, Doueiri MS, Hamad R, Sierwald I et al (2022) The association between molar incisor hypomineralization and oral health-related quality of life: a cross-sectional study. Clin Oral Investig 26(5):4071\u20134077","journal-title":"Clin Oral Investig"}],"container-title":["Clinical Oral Investigations"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00784-024-05490-z.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s00784-024-05490-z\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00784-024-05490-z.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,11,8]],"date-time":"2024-11-08T17:49:02Z","timestamp":1731088142000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s00784-024-05490-z"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,1,20]]},"references-count":41,"journal-issue":{"issue":"1","published-online":{"date-parts":[[2024,1]]}},"alternative-id":["5490"],"URL":"https:\/\/doi.org\/10.1007\/s00784-024-05490-z","relation":{},"ISSN":["1436-3771"],"issn-type":[{"value":"1436-3771","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,1,20]]},"assertion":[{"value":"3 March 2023","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"3 January 2024","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"20 January 2024","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"The study was based on the approval of Hacettepe University\u2019s Non-Interventional Clinical Research Ethics Committee (2020\/03-24) and written consent of the parents.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethics approval and consent to participate"}},{"value":"The authors declare no competing interests.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}}],"article-number":"105"}}