{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,8]],"date-time":"2026-10-08T12:38:31Z","timestamp":1791463111368,"version":"4.3.4"},"reference-count":41,"publisher":"Springer Science and Business Media LLC","issue":"4","license":[{"start":{"date-parts":[[2024,3,19]],"date-time":"2024-03-19T00:00:00Z","timestamp":1710806400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"},{"start":{"date-parts":[[2024,3,19]],"date-time":"2024-03-19T00:00:00Z","timestamp":1710806400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"}],"funder":[{"name":"the Enterprise Joint Fund of Guangdong Province of China","award":["2022A1515220125"],"award-info":[{"award-number":["2022A1515220125"]}]},{"name":"Science and Technology Projects of Guangzhou","award":["202201011034"],"award-info":[{"award-number":["202201011034"]}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Clin Oral Invest"],"DOI":"10.1007\/s00784-024-05567-9","type":"journal-article","created":{"date-parts":[[2024,3,19]],"date-time":"2024-03-19T00:05:24Z","timestamp":1710806724000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Comparing the effectiveness of caries arrest by micro-operative treatment to operative treatment: A 2-year randomized controlled clinical trial"],"prefix":"10.1007","volume":"28","author":[{"given":"Yinuo","family":"Wang","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jie","family":"Wen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ting","family":"Pan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yina","family":"Cao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Huancai","family":"Lin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yan","family":"Zhou","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2024,3,19]]},"reference":[{"key":"5567_CR1","doi-asserted-by":"publisher","first-page":"392","DOI":"10.1177\/00220345211056247","volume":"101","author":"PYF Wen","year":"2022","unstructured":"Wen PYF, Chen MX, Zhong YJ, Dong QQ, Wong HM (2022) Global Burden and Inequality of Dental Caries, 1990 to 2019. J Dent Res 101:392\u2013399. https:\/\/doi.org\/10.1177\/00220345211056247","journal-title":"J Dent Res"},{"key":"5567_CR2","doi-asserted-by":"publisher","first-page":"2","DOI":"10.1186\/1472-6831-4-2","volume":"4","author":"PA Batchelor","year":"2004","unstructured":"Batchelor PA, Sheiham A (2004) Grouping of tooth surfaces by susceptibility to caries: a study in 5\u201316 year-old children. BMC Oral Health 4:2. https:\/\/doi.org\/10.1186\/1472-6831-4-2","journal-title":"BMC Oral Health"},{"key":"5567_CR3","doi-asserted-by":"publisher","first-page":"141","DOI":"10.1159\/000308091","volume":"44","author":"A Sheiham","year":"2010","unstructured":"Sheiham A, Sabbah W (2010) Using universal patterns of caries for planning and evaluating dental care. Caries Res 44:141\u2013150. https:\/\/doi.org\/10.1159\/000308091","journal-title":"Caries Res"},{"key":"5567_CR4","doi-asserted-by":"publisher","first-page":"177","DOI":"10.1159\/000345076","volume":"47","author":"JE Zenkner","year":"2013","unstructured":"Zenkner JE, Alves LS, de Oliveira RS, Bica RH, Wagner MB, Maltz M (2013) Influence of eruption stage and biofilm accumulation on occlusal caries in permanent molars: a generalized estimating equations logistic approach. Caries Res 47:177\u2013182. https:\/\/doi.org\/10.1159\/000345076","journal-title":"Caries Res"},{"key":"5567_CR5","doi-asserted-by":"publisher","first-page":"114s","DOI":"10.1177\/0022034514537646","volume":"93","author":"LS Alves","year":"2014","unstructured":"Alves LS, Zenkner JE, Wagner MB, Dam\u00e9-Teixeira N, Susin C, Maltz M (2014) Eruption stage of permanent molars and occlusal caries activity\/arrest. J Dent Res 93:114s\u2013119s. https:\/\/doi.org\/10.1177\/0022034514537646","journal-title":"J Dent Res"},{"key":"5567_CR6","doi-asserted-by":"publisher","first-page":"181","DOI":"10.3290\/j.cjdr.a41080","volume":"21","author":"JK Quan","year":"2018","unstructured":"Quan JK, Wang XZ, Sun XY, Yuan C, Liu XN, Wang X, Feng XP, Tai BJ, Hu Y, Lin HC, Wang B, Si Y, Wang CX, Wang WJ, Rong WS, Zheng SG (2018) Permanent Teeth caries Status of 12- to 15-year-olds in China: findings from the 4th national oral Health Survey. Chin J Dent Res 21:181\u2013193. https:\/\/doi.org\/10.3290\/j.cjdr.a41080","journal-title":"Chin J Dent Res"},{"key":"5567_CR7","first-page":"32","volume":"3","author":"LW Ripa","year":"1973","unstructured":"Ripa LW (1973) Occlusal sealing: rationale of the technique and historical review. J Am Soc Prev Dent 3:32\u201339","journal-title":"J Am Soc Prev Dent"},{"key":"5567_CR8","doi-asserted-by":"publisher","first-page":"Cd001830","DOI":"10.1002\/14651858.CD001830.pub5","volume":"7","author":"A Ahovuo-Saloranta","year":"2017","unstructured":"Ahovuo-Saloranta A, Forss H, Walsh T, Nordblad A, M\u00e4kel\u00e4 M, Worthington HV (2017) Pit and fissure sealants for preventing dental decay in permanent teeth. Cochrane Database Syst Rev 7:Cd001830. https:\/\/doi.org\/10.1002\/14651858.CD001830.pub5","journal-title":"Cochrane Database Syst Rev"},{"key":"5567_CR9","doi-asserted-by":"publisher","first-page":"631","DOI":"10.1016\/j.adaj.2016.06.003","volume":"147","author":"JT Wright","year":"2016","unstructured":"Wright JT, Tampi MP, Graham L, Estrich C, Crall JJ, Fontana M, Gillette EJ, Nov\u00fd BB, Dhar V, Donly K, Hewlett ER, Quinonez RB, Chaffin J, Crespin M, Iafolla T, Siegal MD, Carrasco-Labra A (2016) Sealants for preventing and arresting pit-and-fissure occlusal caries in primary and permanent molars: a systematic review of randomized controlled trials-a report of the American Dental Association and the American Academy of Pediatric Dentistry. J Am Dent Assoc 147:631\u2013645e18. https:\/\/doi.org\/10.1016\/j.adaj.2016.06.003","journal-title":"J Am Dent Assoc"},{"key":"5567_CR10","doi-asserted-by":"publisher","first-page":"73","DOI":"10.1177\/2380084416680191","volume":"2","author":"V Qvist","year":"2017","unstructured":"Qvist V, Borum MK, M\u00f8ller KD, Andersen TR, Blanche P, Bakhshandeh A (2017) Sealing Occlusal dentin Caries in Permanent molars: 7-Year results of a Randomized Controlled Trial. JDR Clin Trans Res 2:73\u201386. https:\/\/doi.org\/10.1177\/2380084416680191","journal-title":"JDR Clin Trans Res"},{"key":"5567_CR11","doi-asserted-by":"publisher","first-page":"Cd013039","DOI":"10.1002\/14651858.CD013039.pub2","volume":"7","author":"F Schwendicke","year":"2021","unstructured":"Schwendicke F, Walsh T, Lamont T, Al-Yaseen W, Bj\u00f8rndal L, Clarkson JE, Fontana M, Gomez Rossi J, G\u00f6stemeyer G, Levey C, M\u00fcller A, Ricketts D, Robertson M, Santamaria RM, Innes NP (2021) Interventions for treating cavitated or dentine carious lesions. Cochrane Database Syst Rev 7:Cd013039. https:\/\/doi.org\/10.1002\/14651858.CD013039.pub2","journal-title":"Cochrane Database Syst Rev"},{"key":"5567_CR12","doi-asserted-by":"publisher","first-page":"1070","DOI":"10.1177\/0022034514551753","volume":"93","author":"M Fontana","year":"2014","unstructured":"Fontana M, Platt JA, Eckert GJ, Gonz\u00e1lez-Cabezas C, Yoder K, Zero DT, Ando M, Soto-Rojas AE, Peters MC (2014) Monitoring of sound and carious surfaces under sealants over 44 months. J Dent Res 93:1070\u20131075. https:\/\/doi.org\/10.1177\/0022034514551753","journal-title":"J Dent Res"},{"key":"5567_CR13","doi-asserted-by":"publisher","first-page":"103163","DOI":"10.1016\/j.jdent.2019.07.001","volume":"88","author":"C Mu\u00f1oz-Sandoval","year":"2019","unstructured":"Mu\u00f1oz-Sandoval C, Gambetta-Tessini K, Giacaman RA (2019) Microcavitated (ICDAS 3) carious lesion arrest with resin or glass ionomer sealants in first permanent molars: a randomized controlled trial. J Dent 88:103163. https:\/\/doi.org\/10.1016\/j.jdent.2019.07.001","journal-title":"J Dent"},{"key":"5567_CR14","doi-asserted-by":"publisher","first-page":"104205","DOI":"10.1016\/j.jdent.2022.104205","volume":"123","author":"G Ozan","year":"2022","unstructured":"Ozan G, Sancakli HS, Erdemir U, Yaman BC, Yildiz SO, Yildiz E (2022) Comparative evaluation of a fissure sealant and a flowable composite: a 36-month split-mouth, randomized clinical study. J Dent 123:104205. https:\/\/doi.org\/10.1016\/j.jdent.2022.104205","journal-title":"J Dent"},{"key":"5567_CR15","doi-asserted-by":"publisher","first-page":"63","DOI":"10.17096\/jiufd.38691","volume":"49","author":"B Dikmen","year":"2015","unstructured":"Dikmen B (2015) Icdas II criteria (international caries detection and assessment system). J Istanb Univ Fac Dent 49:63\u201372. https:\/\/doi.org\/10.17096\/jiufd.38691","journal-title":"J Istanb Univ Fac Dent"},{"key":"5567_CR16","doi-asserted-by":"publisher","first-page":"79","DOI":"10.1016\/j.adaj.2014.11.018","volume":"146","author":"DA Young","year":"2015","unstructured":"Young DA, Nov\u00fd BB, Zeller GG, Hale R, Hart TC, Truelove EL (2015) The American Dental Association Caries Classification System for clinical practice: a report of the American Dental Association Council on Scientific Affairs. J Am Dent Assoc 146:79\u201386. https:\/\/doi.org\/10.1016\/j.adaj.2014.11.018","journal-title":"J Am Dent Assoc"},{"key":"5567_CR17","doi-asserted-by":"publisher","first-page":"672","DOI":"10.1016\/j.adaj.2016.06.001","volume":"147","author":"JT Wright","year":"2016","unstructured":"Wright JT, Crall JJ, Fontana M, Gillette EJ, Nov\u00fd BB, Dhar V, Donly K, Hewlett ER, Quinonez RB, Chaffin J, Crespin M, Iafolla T, Siegal MD, Tampi MP, Graham L, Estrich C, Carrasco-Labra A (2016) Evidence-based clinical practice guideline for the use of pit-and-fissure sealants: a report of the American Dental Association and the American Academy of Pediatric Dentistry. J Am Dent Assoc 147:672\u2013682e12. https:\/\/doi.org\/10.1016\/j.adaj.2016.06.001","journal-title":"J Am Dent Assoc"},{"key":"5567_CR18","doi-asserted-by":"publisher","first-page":"58","DOI":"10.1177\/0022034516639271","volume":"28","author":"F Schwendicke","year":"2016","unstructured":"Schwendicke F, Frencken JE, Bj\u00f8rndal L, Maltz M, Manton DJ, Ricketts D, Van Landuyt K, Banerjee A, Campus G, Dom\u00e9jean S, Fontana M, Leal S, Lo E, Machiulskiene V, Schulte A, Splieth C, Zandona AF, Innes NP (2016) Managing Carious lesions: Consensus recommendations on Carious tissue removal. Adv Dent Res 28:58\u201367. https:\/\/doi.org\/10.1177\/0022034516639271","journal-title":"Adv Dent Res"},{"key":"5567_CR19","doi-asserted-by":"publisher","first-page":"17","DOI":"10.1038\/s41368-022-00167-3","volume":"14","author":"L Cheng","year":"2022","unstructured":"Cheng L, Zhang L, Yue L, Ling J, Fan M, Yang D, Huang Z, Niu Y, Liu J, Zhao J, Li Y, Guo B, Chen Z, Zhou X (2022) Expert consensus on dental caries management. Int J Oral Sci 14:17. https:\/\/doi.org\/10.1038\/s41368-022-00167-3","journal-title":"Int J Oral Sci"},{"key":"5567_CR20","unstructured":"Water supply quality in Guangzhou (2020) Available online: http:\/\/swj.gz.gov.cn\/mssw\/szy\/szgg\/szgg\/index.html. Accessed 22 Dec 2023)"},{"key":"5567_CR21","doi-asserted-by":"publisher","first-page":"521","DOI":"10.1007\/s00784-011-0549-4","volume":"16","author":"A Bakhshandeh","year":"2012","unstructured":"Bakhshandeh A, Qvist V, Ekstrand KR (2012) Sealing occlusal caries lesions in adults referred for restorative treatment: 2\u20133 years of follow-up. Clin Oral Investig 16:521\u2013529. https:\/\/doi.org\/10.1007\/s00784-011-0549-4","journal-title":"Clin Oral Investig"},{"key":"5567_CR22","doi-asserted-by":"publisher","first-page":"423","DOI":"10.2105\/ajph.94.3.423","volume":"94","author":"DM Murray","year":"2004","unstructured":"Murray DM, Varnell SP, Blitstein JL (2004) Design and analysis of group-randomized trials: a review of recent methodological developments. Am J Public Health 94:423\u2013432. https:\/\/doi.org\/10.2105\/ajph.94.3.423","journal-title":"Am J Public Health"},{"key":"5567_CR23","doi-asserted-by":"publisher","first-page":"753","DOI":"10.1177\/0022034512452278","volume":"91","author":"BY Liu","year":"2012","unstructured":"Liu BY, Lo EC, Chu CH, Lin HC (2012) Randomized trial on fluorides and sealants for fissure caries prevention. J Dent Res 91:753\u2013758. https:\/\/doi.org\/10.1177\/0022034512452278","journal-title":"J Dent Res"},{"key":"5567_CR24","first-page":"42","volume-title":"Oral health surveys: Basic methods","author":"World Health Organization","year":"2013","unstructured":"World Health Organization (2013) Oral health surveys: Basic methods, fifth edn. World Health Organization, Geneva, Switzerland, pp 42\u201347","edition":"fifth"},{"key":"5567_CR25","unstructured":"ICDAS Calibration for ICCMS(TM). Available online: https:\/\/www.iccmsweb.com\/content\/resources\/elearning. Accessed 1 July 2020"},{"key":"5567_CR26","doi-asserted-by":"publisher","first-page":"522","DOI":"10.1177\/0022034515571184","volume":"94","author":"F Schwendicke","year":"2015","unstructured":"Schwendicke F, J\u00e4ger AM, Paris S, Hsu LY, Tu YK (2015) Treating pit-and-fissure caries: a systematic review and network meta-analysis. J Dent Res 94:522\u2013533. https:\/\/doi.org\/10.1177\/0022034515571184","journal-title":"J Dent Res"},{"key":"5567_CR27","doi-asserted-by":"publisher","first-page":"495","DOI":"10.1177\/154405910808700514","volume":"87","author":"MA Hevinga","year":"2008","unstructured":"Hevinga MA, Opdam NJ, Frencken JE, Bronkhorst EM, Truin GJ (2008) Can caries fissures be sealed as adequately as sound fissures? J Dent Res 87:495\u2013498. https:\/\/doi.org\/10.1177\/154405910808700514","journal-title":"J Dent Res"},{"key":"5567_CR28","doi-asserted-by":"publisher","first-page":"e77103","DOI":"10.1371\/journal.pone.0077103","volume":"8","author":"S Mickenautsch","year":"2013","unstructured":"Mickenautsch S, Yengopal V (2013) Validity of sealant retention as surrogate for caries prevention\u2013a systematic review. PLoS ONE 8:e77103. https:\/\/doi.org\/10.1371\/journal.pone.0077103","journal-title":"PLoS ONE"},{"key":"5567_CR29","first-page":"11","volume":"4","author":"SL Handelman","year":"1982","unstructured":"Handelman SL (1982) Effect of sealant placement on occlusal caries progression. Clin Prev Dent 4:11\u201316","journal-title":"Clin Prev Dent"},{"key":"5567_CR30","first-page":"468","volume":"37","author":"E Kucukyilmaz","year":"2015","unstructured":"Kucukyilmaz E, Savas S (2015) Evaluation of different fissure sealant materials and flowable composites used as pit-and-fissure sealants: a 24-Month Clinical Trial. Pediatr Dent 37:468\u2013473","journal-title":"Pediatr Dent"},{"key":"5567_CR31","doi-asserted-by":"publisher","first-page":"943","DOI":"10.1016\/j.adaj.2016.08.003","volume":"147","author":"A Bagherian","year":"2016","unstructured":"Bagherian A, Sarraf Shirazi A (2016) Preparation before acid etching in fissure sealant therapy: yes or no? A systematic review and meta-analysis. J Am Dent Assoc 147:943\u2013951. https:\/\/doi.org\/10.1016\/j.adaj.2016.08.003","journal-title":"J Am Dent Assoc"},{"key":"5567_CR32","doi-asserted-by":"publisher","first-page":"92","DOI":"10.1038\/sj.bdj.2018.40","volume":"224","author":"A Bagherian","year":"2018","unstructured":"Bagherian A, Shirazi AS (2018) Flowable composite as fissure sealing material? A systematic review and meta-analysis. Br Dent J 224:92\u201397. https:\/\/doi.org\/10.1038\/sj.bdj.2018.40","journal-title":"Br Dent J"},{"key":"5567_CR33","doi-asserted-by":"publisher","unstructured":"Waggoner WF, Siegal M (1996) Pit and fissure sealant application: updating the technique. J Am Dent Assoc 127:351\u2009\u2013\u200961, quiz 391-2. https:\/\/doi.org\/10.14219\/jada.archive.1996.0205","DOI":"10.14219\/jada.archive.1996.0205"},{"key":"5567_CR34","doi-asserted-by":"publisher","first-page":"281","DOI":"10.14219\/jada.archive.2008.0157","volume":"139","author":"SO Griffin","year":"2008","unstructured":"Griffin SO, Jones K, Gray SK, Malvitz DM, Gooch BF (2008) Exploring four-handed delivery and retention of resin-based sealants. J Am Dent Assoc 139:281\u2013289 quiz 358. https:\/\/doi.org\/10.14219\/jada.archive.2008.0157","journal-title":"J Am Dent Assoc"},{"key":"5567_CR35","first-page":"483","volume":"42","author":"R Winkler","year":"1991","unstructured":"Winkler R (1991) Sanford Christie Barnum\u2013inventor of the rubber dam. Quintessenz 42:483\u2013486","journal-title":"Quintessenz"},{"key":"5567_CR36","first-page":"23","volume":"19","author":"NA Lygidakis","year":"1994","unstructured":"Lygidakis NA, Oulis KI, Christodoulidis A (1994) Evaluation of fissure sealants retention following four different isolation and surface preparation techniques: four years clinical trial. J Clin Pediatr Dent 19:23\u201325","journal-title":"J Clin Pediatr Dent"},{"key":"5567_CR37","first-page":"61","volume":"6","author":"F Albani","year":"2005","unstructured":"Albani F, Ballesio I, Campanella V, Marzo G (2005) Pit and fissure sealants: results at five and ten years. Eur J Paediatr Dent 6:61\u201365","journal-title":"Eur J Paediatr Dent"},{"key":"5567_CR38","doi-asserted-by":"publisher","first-page":"12","DOI":"10.1111\/ipd.13008","volume":"33","author":"RE Mattar","year":"2023","unstructured":"Mattar RE, Sulimany AM, Binsaleh SS, Hamdan HM, Al-Majed IM (2023) Evaluation of fissure sealant retention rates using Isolite in comparison with rubber dam and cotton roll isolation techniques: a randomized clinical trial. Int J Paediatr Dent 33:12\u201319. https:\/\/doi.org\/10.1111\/ipd.13008","journal-title":"Int J Paediatr Dent"},{"key":"5567_CR39","doi-asserted-by":"publisher","first-page":"101587","DOI":"10.1016\/j.jebdp.2021.101587","volume":"21","author":"PP Lam","year":"2021","unstructured":"Lam PP, Sardana D, Lo EC, Yiu CK (2021) FISSURE SEALANT IN A NUTSHELL. EVIDENCE-BASED META-EVALUATION OF SEALANTS\u2019 EFFECTIVENESS IN CARIES PREVENTION AND ARREST. J Evid Based Dent Pract 21:101587. https:\/\/doi.org\/10.1016\/j.jebdp.2021.101587","journal-title":"J Evid Based Dent Pract"},{"key":"5567_CR40","doi-asserted-by":"publisher","first-page":"760","DOI":"10.1111\/ipd.12758","volume":"31","author":"P Kasemkhun","year":"2021","unstructured":"Kasemkhun P, Nakornchai S, Phonghanyudh A, Srimaneekarn N (2021) The efficacy of dental sealant used with bonding agent on occlusal caries (ICDAS 2\u20134): a 24-month randomized clinical trial. Int J Paediatr Dent 31:760\u2013766. https:\/\/doi.org\/10.1111\/ipd.12758","journal-title":"Int J Paediatr Dent"},{"key":"5567_CR41","doi-asserted-by":"publisher","first-page":"8","DOI":"10.1016\/j.jdent.2017.08.004","volume":"66","author":"SN Papageorgiou","year":"2017","unstructured":"Papageorgiou SN, Dimitraki D, Kotsanos N, Bekes K, van Waes H (2017) Performance of pit and fissure sealants according to tooth characteristics: a systematic review and meta-analysis. J Dent 66:8\u201317. https:\/\/doi.org\/10.1016\/j.jdent.2017.08.004","journal-title":"J Dent"}],"container-title":["Clinical Oral Investigations"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00784-024-05567-9.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s00784-024-05567-9\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00784-024-05567-9.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,4,12]],"date-time":"2024-04-12T06:08:29Z","timestamp":1712902109000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s00784-024-05567-9"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,3,19]]},"references-count":41,"journal-issue":{"issue":"4","published-online":{"date-parts":[[2024,4]]}},"alternative-id":["5567"],"URL":"https:\/\/doi.org\/10.1007\/s00784-024-05567-9","relation":{},"ISSN":["1436-3771"],"issn-type":[{"value":"1436-3771","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,3,19]]},"assertion":[{"value":"22 December 2023","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"17 February 2024","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"19 March 2024","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"This study protocol was reviewed and approved by the Medical Ethics Committee of Hospital of Stomatology (KQEC-2019-45). It has been carried out in accordance with the Code of Ethics of the World Medical Association (Declaration of Helsinki) for experiments involving humans. The written informed consent was obtained from the participant\u2019s guardian. This trial was registered on the Chinese Clinical Trial Registry (), the number is ChiCTR2000029862.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethics approval and consent to participate"}},{"value":"The authors declare no competing interests.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}}],"article-number":"222"}}