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Patients were randomly assigned to receive coronally advanced flap (CAF) with either CTG (control) or L-PRF (test) treatment. Various parameters, including plaque and gingival index, clinical attachment level, recession depth, probing depth, recession width (RW), papilla width (PW), keratinized tissue width (KTW), gingival thickness (GT), percentage of RC, complete root coverage (CRC), and location of the relative gingival margin concerning the cemento-enamel junctions (GMCEJ) after CAF, were recorded at baseline, 3-, 6-, and 12-months post-surgery. On June 29, 2021 the study was registred to ClinicalTrials.gov (NCT04942821).<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Results<\/jats:title>\n                <jats:p>Except KTW and GT gain, all clinical parameters, RC, and CRC were similar between the groups at all follow-up periods (<jats:italic>p<\/jats:italic>\u2009&gt;\u20090.05). The higher GT and KTW gains were detected in the control group compared to test group at 12 months (<jats:italic>p<\/jats:italic>\u2009&lt;\u20090.05). Both RC and CRC were positively associated with initial PW and GMCEJ, but negatively with initial RW (<jats:italic>p<\/jats:italic>\u2009&lt;\u20090.05).<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Conclusions<\/jats:title>\n                <jats:p>The current study concludes that L-PRF were equally effective as CTG in treating MAGRs in terms of RC and CRC. Additionally, RC and CRC outcomes appeared to be influenced by GMCEJ, PW, and RW.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Clinical relevance<\/jats:title>\n                <jats:p>L-PRF could represent a feasible substitute for CTG in treating MAGRs.<\/jats:p>\n              <\/jats:sec>","DOI":"10.1007\/s00784-024-05694-3","type":"journal-article","created":{"date-parts":[[2024,5,1]],"date-time":"2024-05-01T12:52:52Z","timestamp":1714567972000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":8,"title":["Treatment of multiple adjacent gingival recessions using leucocyte- and platelet-rich fibrin with coronally advanced flap: a 12-month split-mouth controlled randomized clinical trial"],"prefix":"10.1007","volume":"28","author":[{"given":"Atacan","family":"Yavuz","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hatice Selin","family":"G\u00fcng\u00f6rmek","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Leyla","family":"Kuru","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ba\u015fak","family":"Do\u011fan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2024,5,1]]},"reference":[{"key":"5694_CR1","doi-asserted-by":"publisher","first-page":"296","DOI":"10.1111\/prd.12186","volume":"75","author":"F Cairo","year":"2017","unstructured":"Cairo F (2017) Periodontal plastic surgery of gingival recessions at single and multiple teeth. 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Written informed consent to participate in this study was obtained from all participants.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethics approval and consent to participate"}},{"value":"Patients signed informed consent regarding publishing their data and photographs.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent for publication"}},{"value":"The authors declare no competing interests.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}},{"value":"Not applicable.","order":5,"name":"Ethics","group":{"name":"EthicsHeading","label":"Author information"}}],"article-number":"291"}}