{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,23]],"date-time":"2026-07-23T22:44:43Z","timestamp":1784846683392,"version":"3.55.0"},"reference-count":72,"publisher":"Springer Science and Business Media LLC","issue":"6","license":[{"start":{"date-parts":[[2024,5,21]],"date-time":"2024-05-21T00:00:00Z","timestamp":1716249600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"},{"start":{"date-parts":[[2024,5,21]],"date-time":"2024-05-21T00:00:00Z","timestamp":1716249600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"}],"funder":[{"DOI":"10.13039\/501100006389","name":"University of Geneva","doi-asserted-by":"crossref","id":[{"id":"10.13039\/501100006389","id-type":"DOI","asserted-by":"crossref"}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Clin Oral Invest"],"abstract":"<jats:title>Abstract<\/jats:title><jats:sec>\n                <jats:title>Objectives<\/jats:title>\n                <jats:p>The aim of this multi-center pilot study was to assess the viability and feasibility of a novel treatment concept \u2013 the canine-positioned single implant mandibular overdenture (c-SIMO), with the single implant placed on the patient's preferred chewing side instead of the midline.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Materials and methods<\/jats:title>\n                <jats:p>Participants received a single implant in the canine region of their preferred chewing side, based on an Asymmetry Index observed during mastication. The pre-existing mandibular denture was transformed into a c-SIMO on a spherical attachment. The primary outcome was oral health-related quality of life (OHRQoL), measured with GOHAI and OHIP-EDENT. Secondary outcomes included denture satisfaction index (DSI), chewing efficiency (CE), maximum bite force (MBF), implant survival and success, and prosthetic maintenance. Data analysis included descriptive statistics and bivariate comparison tests.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Results<\/jats:title>\n                <jats:p>Fifteen participants received the c-SIMO treatment (mean age: 69.9\u2009\u00b1\u20097.0). Implant success and survival rates were 100% at 1\u00a0year. Patient-reported outcome measures improved significantly compared to pre-treatment values (OHIP-EDENT: <jats:italic>p<\/jats:italic>\u2009=\u20090.001; DSI: <jats:italic>p<\/jats:italic>\u2009=\u20090.001; GOHAI: <jats:italic>p<\/jats:italic>\u2009=\u20090.002). Masticatory outcomes also improved significantly (CE: <jats:italic>p<\/jats:italic>\u2009=\u20090.001; overall MBF: <jats:italic>p<\/jats:italic>\u2009=\u20090.005). Post-implant, MBF was significantly higher in the ipsilateral side compared to the contralateral side at 2\u00a0weeks (<jats:italic>p<\/jats:italic>\u2009=\u20090.019) and 3\u00a0months (<jats:italic>p<\/jats:italic>\u2009=\u20090.015), but no longer at T3 (<jats:italic>p<\/jats:italic>\u2009=\u20090.730). Common prosthodontic events included denture base adjustments (<jats:italic>n<\/jats:italic>\u2009=\u200917) and matrix activation (<jats:italic>n<\/jats:italic>\u2009=\u20099).<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Conclusions<\/jats:title>\n                <jats:p>This pilot study concludes that c-SIMO is a promising treatment option, and a potential alternative to the single midline implant overdenture.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Clinical relevance<\/jats:title>\n                <jats:p>The novel treatment concept of a canine-positioned single implant mandibular overdenture could be a viable treatment alternative to the midline positioning.<\/jats:p>\n              <\/jats:sec>","DOI":"10.1007\/s00784-024-05723-1","type":"journal-article","created":{"date-parts":[[2024,5,21]],"date-time":"2024-05-21T19:01:41Z","timestamp":1716318101000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":4,"title":["Mandibular overdenture with a single implant in the canine region (c-SIMO): a feasibility study"],"prefix":"10.1007","volume":"28","author":[{"given":"Sabrina","family":"Maniewicz","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Thalita Fernandes Fleury","family":"Curado","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Murali","family":"Srinivasan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Cl\u00e1udio Rodrigues","family":"Leles","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Frauke","family":"M\u00fcller","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2024,5,21]]},"reference":[{"key":"5723_CR1","unstructured":"(2019) ASA physical status classification system. 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