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The aim of this retrospective study was to determine the long-term associations between both in orthodontic patients.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Materials and methods<\/jats:title>\n                <jats:p>103 patients aged 36.6\u2009\u00b1\u20096.5 years whose fixed appliance orthodontic treatment had finished at least 15 years ago were included. Current clinical data and photographs (T3), panoramic x-ray and photographs from before treatment (T0), after debonding (T1) and at 2-year follow-up (T2) were available. Parameters of interest were dentine caries, \u201cMissing\/Filled Teeth\u201d (MFT), \u201cWhite Spot Lesion\u201d (WSL) index and \u201cPeriodontal Screening and Recording\u201d index (PSR; T3 only).<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Results<\/jats:title>\n                <jats:p>At T0, 30.4% had no caries experience decreasing to 25.6%, 22.4% and 6.8% at T1, T2 and T3 resp. The median MFT (95% CI) at T0, T1, T2 and T3 was 2 (1;3), 3 (2;4), 3 (2;4) and 7 (6;9) resp. increasing significantly at each time point (<jats:italic>p<\/jats:italic>\u2009&lt;\u20090.001 each); 30.1% had WSL at debonding. Patients with caries experience at T0 had a 2.4-fold increased risk of WSL at debonding. Dentine caries, caries experience and WSL at T1 were significantly associated with incident caries at T2, but not at T3. PSR at T3 had a significant association with previous caries incidence and WSL.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Conclusions<\/jats:title>\n                <jats:p>Caries experience prior to orthodontic treatment may constitute a risk indicator for WSL, and caries experience and WSL at its end for caries incidence in the near term.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Clinical Relevance<\/jats:title>\n                <jats:p> Present caries and WSL may help identifying orthodontic patients with special need for prevention and counselling.<\/jats:p>\n              <\/jats:sec>","DOI":"10.1007\/s00784-024-05752-w","type":"journal-article","created":{"date-parts":[[2024,6,11]],"date-time":"2024-06-11T11:14:12Z","timestamp":1718104452000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":8,"title":["Caries and white spot lesion trajectories of orthodontic patients across an observation period of 20 years"],"prefix":"10.1007","volume":"28","author":[{"given":"Carolina","family":"Ganss","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nelly","family":"Schulz-Weidner","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Katharina","family":"Klaus","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Julia","family":"von Bremen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sabine","family":"Ruf","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Niko C.","family":"Bock","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2024,6,11]]},"reference":[{"key":"5752_CR1","doi-asserted-by":"publisher","first-page":"1710953","DOI":"10.1080\/20002297.2019.1710953","volume":"12","author":"B Nyvad","year":"2020","unstructured":"Nyvad B, Takahashi N (2020) Integrated hypothesis of dental caries and periodontal diseases. 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