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The implants were categorized Group-1(peri-implant mucositis), Group-2(peri-implantitis).Baseline (0. Month-PrT) clinical parameters (PD, GI, PI, BOP, CAL) and radiographic bone loss were documented, and peri-implant crevicular fluid (PICF) samples were collected. Various intruments and methodologies were employed to assess PPh components (mucosa thickness, supracrestal tissue height, keratinized mucosa) and peri-implant attached mucosa (AM). NSMT was applied to diseased implant sites. All clinical parameters were reassessed again by taking PICF samples at the 6th month-after treatment (PT). In PICF samples obtained from both groups, MMP-8 and CLP levels were evaluated using the ELISA test.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Results<\/jats:title>\n                <jats:p>PrT-PD,PrT-GI,PrT-CAL and PrT-BOP percentage values in Group-2 were significantly higher than Group-1.PrT-PD,PrTPI scores are significantly higher in thin biotype implants. All components of the PPh and AM were significantly lower in thin biotype. Intra-group time-dependent changes of MMP-8 and CLP were significant in both groups (<jats:italic>p<\/jats:italic>\u2009&lt;\u20090.05). When the relationship between thin and thick biotype and biochemical parameters was evaluated, the change in PrT-PT didn\u2019t show a significant difference (<jats:italic>p<\/jats:italic>\u2009&gt;\u20090.05).<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Conclusions<\/jats:title>\n                <jats:p>PPh plays a role in influencing the severity of peri-implant diseases. However, the impact of phenotype on NSMT outcomes was similar in both groups.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Clinical relevance<\/jats:title>\n                <jats:p>The PPh should be considered when planning implant surgery.<\/jats:p>\n              <\/jats:sec>","DOI":"10.1007\/s00784-024-05798-w","type":"journal-article","created":{"date-parts":[[2024,6,28]],"date-time":"2024-06-28T05:02:05Z","timestamp":1719550925000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":11,"title":["Peri-implant phenotype, calprotectin and MMP-8 levels in cases diagnosed with peri-implant disease"],"prefix":"10.1007","volume":"28","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-6006-3375","authenticated-orcid":false,"given":"Yasemin Beliz","family":"\u00d6nder","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6311-385X","authenticated-orcid":false,"given":"Nazli Zeynep","family":"Alpaslan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2024,6,28]]},"reference":[{"key":"5798_CR1","doi-asserted-by":"publisher","first-page":"125","DOI":"10.1111\/j.1600-0757.1998.tb00130.x","volume":"17","author":"JP Fiorellini","year":"1998","unstructured":"Fiorellini JP., Martuscelli G, Weber HP (1998) Longitudinal studies of implant systems. 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