{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,12]],"date-time":"2026-06-12T23:37:20Z","timestamp":1781307440659,"version":"3.54.1"},"reference-count":59,"publisher":"Springer Science and Business Media LLC","issue":"9","license":[{"start":{"date-parts":[[2024,8,28]],"date-time":"2024-08-28T00:00:00Z","timestamp":1724803200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"},{"start":{"date-parts":[[2024,8,28]],"date-time":"2024-08-28T00:00:00Z","timestamp":1724803200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"}],"funder":[{"name":"The Scientific Research Fund of Gazi University","award":["03\/2020-21"],"award-info":[{"award-number":["03\/2020-21"]}]},{"name":"The Scientific Research Fund of Gazi University","award":["03\/2020-21"],"award-info":[{"award-number":["03\/2020-21"]}]},{"name":"The Scientific Research Fund of Gazi University","award":["03\/2020-21"],"award-info":[{"award-number":["03\/2020-21"]}]},{"name":"The Scientific Research Fund of Gazi University","award":["03\/2020-21"],"award-info":[{"award-number":["03\/2020-21"]}]},{"name":"The Scientific Research Fund of Gazi University","award":["03\/2020-21"],"award-info":[{"award-number":["03\/2020-21"]}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Clin Oral Invest"],"DOI":"10.1007\/s00784-024-05891-0","type":"journal-article","created":{"date-parts":[[2024,8,28]],"date-time":"2024-08-28T09:02:56Z","timestamp":1724835776000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":10,"title":["Prevention of secondary caries using fluoride-loaded chitosan nanoparticle-modified glass-ionomer cement"],"prefix":"10.1007","volume":"28","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-7430-4750","authenticated-orcid":false,"given":"Hanife","family":"Alt\u0131n\u0131\u015f\u0131k","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1784-8900","authenticated-orcid":false,"given":"H\u00fclya","family":"Erten Can","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4882-3124","authenticated-orcid":false,"given":"Necibe Ba\u015faran","family":"Mutlu A\u011fardan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4669-5496","authenticated-orcid":false,"given":"Aysel","family":"Berkkan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8478-1072","authenticated-orcid":false,"given":"Mustafa","family":"G\u00fcney","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2024,8,28]]},"reference":[{"issue":"2","key":"5891_CR1","doi-asserted-by":"publisher","first-page":"107","DOI":"10.1016\/j.jebdp.2016.05.001","volume":"16","author":"M Alhareky","year":"2016","unstructured":"Alhareky M, Tavares M (2016) Amalgam vs Composite Restoration, Survival, and secondary caries. J Evid Based Dent Pract 16(2):107\u2013109","journal-title":"J Evid Based Dent Pract"},{"issue":"12","key":"5891_CR2","doi-asserted-by":"publisher","first-page":"e1","DOI":"10.1016\/j.dental.2023.10.008","volume":"39","author":"KX Ge","year":"2023","unstructured":"Ge KX, Quock R, Chu CH, Yu OY (2023) The preventive effect of glass ionomer cement restorations on secondary caries formation: a systematic review and meta-analysis. Dent Materials: Official Publication Acad Dent Mater 39(12):e1\u2013e17","journal-title":"Dent Materials: Official Publication Acad Dent Mater"},{"issue":"2","key":"5891_CR3","doi-asserted-by":"publisher","first-page":"683","DOI":"10.1007\/s00784-019-02894-0","volume":"24","author":"I Nedeljkovic","year":"2020","unstructured":"Nedeljkovic I, De Munck J, Vanloy A, Declerck D, Lambrechts P, Peumans M, Teughels W, Van Meerbeek B, Van Landuyt KL (2020) Secondary caries: prevalence, characteristics, and approach. Clin Oral Invest 24(2):683\u2013691","journal-title":"Clin Oral Invest"},{"issue":"2","key":"5891_CR4","doi-asserted-by":"publisher","first-page":"1019","DOI":"10.1007\/s00784-017-2184-1","volume":"22","author":"N Kr\u00e4mer","year":"2018","unstructured":"Kr\u00e4mer N, Schmidt M, L\u00fccker S, Domann E, Frankenberger R (2018) Glass Ionomer cement inhibits secondary caries in an in vitro biofilm model. Clin Oral Invest 22(2):1019\u20131031","journal-title":"Clin Oral Invest"},{"issue":"3","key":"5891_CR5","doi-asserted-by":"publisher","first-page":"177","DOI":"10.1016\/j.adaj.2015.09.016","volume":"147","author":"DP Raggio","year":"2016","unstructured":"Raggio DP, Tedesco TK, Calvo AF, Braga MM (2016) Do glass ionomer cements prevent caries lesions in margins of restorations in primary teeth? A systematic review and meta-analysis. J Am Dent Assoc 147(3):177\u2013185","journal-title":"J Am Dent Assoc"},{"issue":"4","key":"5891_CR6","doi-asserted-by":"publisher","first-page":"447","DOI":"10.1159\/000496401","volume":"53","author":"F Hetrodt","year":"2019","unstructured":"Hetrodt F, Lausch J, Meyer-Lueckel H, Conrads G, Apel C (2019) Evaluation of restorative materials containing preventive additives in a secondary Caries Model in vitro. Caries Res 53(4):447\u2013456","journal-title":"Caries Res"},{"issue":"3","key":"5891_CR7","first-page":"165","volume":"31","author":"IA Mj\u00f6r","year":"2000","unstructured":"Mj\u00f6r IA, Toffenetti F (2000) Secondary caries: a literature review with case reports. Quintessence Int 31(3):165\u2013179","journal-title":"Quintessence Int"},{"issue":"2","key":"5891_CR8","doi-asserted-by":"publisher","first-page":"71","DOI":"10.1111\/idj.12207","volume":"66","author":"ML Mei","year":"2016","unstructured":"Mei ML, Zhao IS, Ito L, Lo EC, Chu CH (2016) Prevention of secondary caries by silver diamine fluoride. Int Dent J 66(2):71\u201377","journal-title":"Int Dent J"},{"issue":"4","key":"5891_CR9","doi-asserted-by":"publisher","first-page":"409","DOI":"10.1177\/0885328215589672","volume":"30","author":"MA Ibrahim","year":"2015","unstructured":"Ibrahim MA, Neo J, Esguerra RJ, Fawzy AS (2015) Characterization of antibacterial and adhesion properties of chitosan-modified glass ionomer cement. J Biomater Appl 30(4):409\u2013419","journal-title":"J Biomater Appl"},{"issue":"Pt B","key":"5891_CR10","doi-asserted-by":"publisher","first-page":"1860","DOI":"10.1016\/j.ijbiomac.2017.05.120","volume":"104","author":"R Senthil Kumar","year":"2017","unstructured":"Senthil Kumar R, Ravikumar N, Kavitha S, Mahalaxmi S, Jayasree R, Sampath Kumar TS, Haneesh M (2017) Nanochitosan modified glass ionomer cement with enhanced mechanical properties and fluoride release. Int J Biol Macromol 104(Pt B):1860\u20131865","journal-title":"Int J Biol Macromol"},{"issue":"3","key":"5891_CR11","first-page":"Zc75","volume":"11","author":"A Debnath","year":"2017","unstructured":"Debnath A, Kesavappa SB, Singh GP, Eshwar S, Jain V, Swamy M, Shetty P (2017) Comparative Evaluation of Antibacterial and Adhesive properties of Chitosan Modified Glass Ionomer Cement and Conventional Glass Ionomer Cement: an in vitro study. J Clin Diagn Res 11(3):Zc75\u2013zc78","journal-title":"J Clin Diagn Res"},{"issue":"8","key":"5891_CR12","doi-asserted-by":"publisher","first-page":"1004","DOI":"10.1016\/j.dental.2006.06.038","volume":"23","author":"DF Petri","year":"2007","unstructured":"Petri DF, Doneg\u00e1 J, Benassi AM, Bocangel JA (2007) Preliminary study on Chitosan modified glass ionomer restoratives. Dent Materials: Official Publication Acad Dent Mater 23(8):1004\u20131010","journal-title":"Dent Materials: Official Publication Acad Dent Mater"},{"issue":"8","key":"5891_CR13","doi-asserted-by":"publisher","first-page":"e737","DOI":"10.4317\/jced.55996","volume":"13","author":"F Sharafeddin","year":"2021","unstructured":"Sharafeddin F, Jowkar Z, Bahrani S (2021) Comparison between the effect of adding microhydroxyapatite and chitosan on surface roughness and microhardness of resin modified and conventional glass ionomer cements. J Clin Exp Dent 13(8):e737\u2013e744","journal-title":"J Clin Exp Dent"},{"key":"5891_CR14","doi-asserted-by":"crossref","unstructured":"Sonia T, Sharma CP Chitosan and its derivatives for drug delivery perspective. Chitosan Biomaterials I 2011:23\u201353","DOI":"10.1007\/12_2011_117"},{"key":"5891_CR15","doi-asserted-by":"publisher","first-page":"326","DOI":"10.1016\/j.ejps.2017.04.004","volume":"104","author":"S Nguyen","year":"2017","unstructured":"Nguyen S, Escudero C, Sediqi N, Smistad G, Hiorth M (2017) Fluoride loaded polymeric nanoparticles for dental delivery. Eur J Pharm Sci 104:326\u2013334","journal-title":"Eur J Pharm Sci"},{"issue":"1","key":"5891_CR16","doi-asserted-by":"publisher","first-page":"11","DOI":"10.1016\/j.dental.2015.09.006","volume":"32","author":"A Jokstad","year":"2016","unstructured":"Jokstad A (2016) Secondary caries and microleakage. Dent Materials: Official Publication Acad Dent Mater 32(1):11\u201325","journal-title":"Dent Materials: Official Publication Acad Dent Mater"},{"issue":"1","key":"5891_CR17","doi-asserted-by":"publisher","first-page":"9","DOI":"10.2209\/tdcpublication.44.9","volume":"44","author":"H Sano","year":"2003","unstructured":"Sano H, Shibasaki K, Matsukubo T, Takaesu Y (2003) Effect of chitosan rinsing on reduction of dental plaque formation. Bull Tokyo Dent Coll 44(1):9\u201316","journal-title":"Bull Tokyo Dent Coll"},{"issue":"4","key":"5891_CR18","doi-asserted-by":"publisher","first-page":"243","DOI":"10.2209\/tdcpublication.42.243","volume":"42","author":"H Sano","year":"2001","unstructured":"Sano H, Shibasaki K, Matsukubo T, Takaesu Y (2001) Comparison of the activity of four chitosan derivatives in reducing initial adherence of oral bacteria onto tooth surfaces. Bull Tokyo Dent Coll 42(4):243\u2013249","journal-title":"Bull Tokyo Dent Coll"},{"key":"5891_CR19","doi-asserted-by":"crossref","unstructured":"Kuang X, Chen V, Xu X (2018) Novel Approaches to the Control of Oral Microbial Biofilms. Biomed Res Int 2018:6498932","DOI":"10.1155\/2018\/6498932"},{"issue":"2","key":"5891_CR20","first-page":"93","volume":"8","author":"A Aliasghari","year":"2016","unstructured":"Aliasghari A, Khorasgani MR, Vaezifar S, Rahimi F, Younesi H, Khoroushi M (2016) Evaluation of antibacterial efficiency of Chitosan and Chitosan nanoparticles on cariogenic streptococci: an in vitro study. Iran J Microbiol 8(2):93","journal-title":"Iran J Microbiol"},{"issue":"11","key":"5891_CR21","doi-asserted-by":"publisher","first-page":"3892","DOI":"10.1128\/AEM.02941-10","volume":"77","author":"LE Ch\u00e1vez de Paz","year":"2011","unstructured":"Ch\u00e1vez de Paz LE, Resin A, Howard KA, Sutherland DS, Wejse PL (2011) Antimicrobial effect of chitosan nanoparticles on Streptococcus mutans biofilms. Appl Environ Microbiol 77(11):3892\u20133895","journal-title":"Appl Environ Microbiol"},{"issue":"6","key":"5891_CR22","doi-asserted-by":"publisher","first-page":"785","DOI":"10.1016\/j.identj.2022.05.005","volume":"72","author":"C Nishanthine","year":"2022","unstructured":"Nishanthine C, Miglani R, Poorni RI, Srinivasan S, Robaian MR, Albar A, Alhaidary NHM, Binalrimal SFR, Almalki S (2022) Evaluation of Fluoride Release in Chitosan-Modified Glass Ionomer cements. Int Dent J 72(6):785\u2013791","journal-title":"Int Dent J"},{"issue":"1","key":"5891_CR23","first-page":"54","volume":"50","author":"NB Mutlu A\u011fardan","year":"2020","unstructured":"Mutlu A\u011fardan NB (2020) Studies on the formulation optimization and controlled ionic gelation of chitosan nanoparticles using TPP-HP-\u03b2-CD inclusion complex. \u0130stanbul J Pharm 50(1):54\u201359","journal-title":"\u0130stanbul J Pharm"},{"issue":"10","key":"5891_CR24","doi-asserted-by":"publisher","first-page":"1431","DOI":"10.1023\/A:1012128907225","volume":"14","author":"P Calvo","year":"1997","unstructured":"Calvo P, Remu\u00f1an-L\u00f3pez C, Vila-Jato JL, Alonso MJ (1997) Chitosan and Chitosan\/Ethylene Oxide-Propylene Oxide Block Copolymer Nanoparticles as Novel Carriers for proteins and vaccines. Pharm Res 14(10):1431\u20131436","journal-title":"Pharm Res"},{"issue":"2","key":"5891_CR25","doi-asserted-by":"publisher","first-page":"205","DOI":"10.1016\/j.materresbull.2010.11.015","volume":"46","author":"W Liang","year":"2011","unstructured":"Liang W, Zhan L, Piao L, R\u0171ssel C (2011) Fluoride removal performance of glass derived hydroxyapatite. Mater Res Bull 46(2):205\u2013209","journal-title":"Mater Res Bull"},{"issue":"1","key":"5891_CR26","doi-asserted-by":"publisher","first-page":"344","DOI":"10.1016\/j.jmrt.2018.01.010","volume":"8","author":"RAS Alatawi","year":"2019","unstructured":"Alatawi RAS, Elsayed NH, Mohamed WS (2019) Influence of hydroxyapatite nanoparticles on the properties of glass ionomer cement. J Mater Res Technol 8(1):344\u2013349","journal-title":"J Mater Res Technol"},{"key":"5891_CR27","doi-asserted-by":"crossref","unstructured":"Zhao IS, Mei ML, Burrow MF, Lo EC, Chu CH (2017) Effect of silver diamine fluoride and potassium iodide treatment on Secondary Caries Prevention and Tooth Discolouration in Cervical Glass Ionomer Cement Restoration. Int J Mol Sci 18(2)","DOI":"10.3390\/ijms18020340"},{"issue":"2","key":"5891_CR28","doi-asserted-by":"publisher","first-page":"71","DOI":"10.1111\/idj.12207","volume":"66","author":"ML Mei","year":"2016","unstructured":"Mei ML, Zhao IS, Ito L, Lo EC-M, Chu C-H (2016) Prevention of secondary caries by silver diamine fluoride. Int Dent J 66(2):71\u201377","journal-title":"Int Dent J"},{"issue":"1","key":"5891_CR29","doi-asserted-by":"publisher","first-page":"3","DOI":"10.1002\/jbmr.5650040103","volume":"4","author":"LA Feldkamp","year":"1989","unstructured":"Feldkamp LA, Goldstein SA, Parfitt AM, Jesion G, Kleerekoper M (1989) The direct examination of three-dimensional bone architecture in vitro by computed tomography. J Bone Min Res 4(1):3\u201311","journal-title":"J Bone Min Res"},{"issue":"1","key":"5891_CR30","doi-asserted-by":"publisher","first-page":"35","DOI":"10.2485\/jhtb.18.35","volume":"18","author":"T Kawato","year":"2009","unstructured":"Kawato T, Furuta M, Ogiso B, Yamashita Y, Kitami S, Iida T, Kuwabara A, Maeno M (2009) Evaluating occlusal caries using a non-destructive micro-CT examination. J Hard Tissue Biol 18(1):35\u201339","journal-title":"J Hard Tissue Biol"},{"key":"5891_CR31","doi-asserted-by":"publisher","first-page":"38","DOI":"10.1016\/j.jdent.2016.12.001","volume":"57","author":"IS Zhao","year":"2017","unstructured":"Zhao IS, Mei ML, Burrow MF, Lo EC, Chu CH (2017) Prevention of secondary caries using silver diamine fluoride treatment and casein phosphopeptide-amorphous calcium phosphate modified glass-ionomer cement. J Dent 57:38\u201344","journal-title":"J Dent"},{"issue":"1","key":"5891_CR32","doi-asserted-by":"publisher","first-page":"e08674","DOI":"10.1016\/j.heliyon.2021.e08674","volume":"8","author":"Y Herdiana","year":"2022","unstructured":"Herdiana Y, Wathoni N, Shamsuddin S, Muchtaridi M (2022) Drug release study of the chitosan-based nanoparticles. Heliyon 8(1):e08674","journal-title":"Heliyon"},{"issue":"2","key":"5891_CR33","doi-asserted-by":"publisher","first-page":"123","DOI":"10.1016\/S0928-0987(01)00095-1","volume":"13","author":"P Costa","year":"2001","unstructured":"Costa P, Sousa Lobo JM (2001) Modeling and comparison of dissolution profiles. Eur J Pharm Sci 13(2):123\u2013133","journal-title":"Eur J Pharm Sci"},{"issue":"3","key":"5891_CR34","doi-asserted-by":"publisher","first-page":"263","DOI":"10.1208\/s12248-010-9185-1","volume":"12","author":"Y Zhang","year":"2010","unstructured":"Zhang Y, Huo M, Zhou J, Zou A, Li W, Yao C, Xie S (2010) DDSolver: an add-in program for modeling and comparison of drug dissolution profiles. AAPS J 12(3):263\u2013271","journal-title":"AAPS J"},{"issue":"12","key":"5891_CR35","doi-asserted-by":"publisher","first-page":"370","DOI":"10.3390\/md15120370","volume":"15","author":"MM Silva","year":"2017","unstructured":"Silva MM, Calado R, Marto J, Bettencourt A, Almeida AJ, Gon\u00e7alves LMD (2017) Chitosan Nanoparticles as a Mucoadhesive Drug Delivery System for Ocular Administration. Mar Drugs 15(12):370","journal-title":"Mar Drugs"},{"issue":"2","key":"5891_CR36","doi-asserted-by":"publisher","first-page":"127","DOI":"10.33073\/pjm-2014-018","volume":"63","author":"I Struzycka","year":"2014","unstructured":"Struzycka I (2014) The oral microbiome in dental caries. Pol J Microbiol 63(2):127\u2013135","journal-title":"Pol J Microbiol"},{"issue":"9555","key":"5891_CR37","doi-asserted-by":"publisher","first-page":"51","DOI":"10.1016\/S0140-6736(07)60031-2","volume":"369","author":"RH Selwitz","year":"2007","unstructured":"Selwitz RH, Ismail AI, Pitts NB (2007) Dental caries. Lancet 369(9555):51\u201359","journal-title":"Lancet"},{"key":"5891_CR38","doi-asserted-by":"crossref","unstructured":"Amaechi BT, Abdul Azees PA, Farah R, Movaghari Pour F, Dillow AM, Lin CY (2023) Evaluation of an Artificial Mouth for Dental Caries Development. Microorganisms 11(3)","DOI":"10.3390\/microorganisms11030628"},{"issue":"1","key":"5891_CR39","doi-asserted-by":"publisher","first-page":"21","DOI":"10.1590\/S0103-64402008000100004","volume":"19","author":"CS Queiroz","year":"2008","unstructured":"Queiroz CS, Hara AT, Paes Leme AF, Cury JA (2008) pH-cycling models to evaluate the effect of low fluoride dentifrice on enamel de- and remineralization. Braz Dent J 19(1):21\u201327","journal-title":"Braz Dent J"},{"issue":"5","key":"5891_CR40","first-page":"322","volume":"24","author":"GK Stookey","year":"2011","unstructured":"Stookey GK, Featherstone JD, Rapozo-Hilo M, Schemehorn BR, Williams RA, Baker RA, Barker ML, Kaminski MA, McQueen CM, Amburgey JS et al (2011) The Featherstone laboratory pH cycling model: a prospective, multi-site validation exercise. Am J Dent 24(5):322\u2013328","journal-title":"Am J Dent"},{"key":"5891_CR41","doi-asserted-by":"publisher","first-page":"4","DOI":"10.1186\/1476-0711-12-4","volume":"12","author":"ML Mei","year":"2013","unstructured":"Mei ML, Li QL, Chu CH, Lo EC, Samaranayake LP (2013) Antibacterial effects of silver diamine fluoride on multi-species cariogenic biofilm on caries. Ann Clin Microbiol Antimicrob 12:4","journal-title":"Ann Clin Microbiol Antimicrob"},{"key":"5891_CR42","doi-asserted-by":"publisher","first-page":"295","DOI":"10.1016\/j.jmbbm.2013.09.013","volume":"29","author":"AL Morresi","year":"2014","unstructured":"Morresi AL, D\u2019Amario M, Capogreco M, Gatto R, Marzo G, D\u2019Arcangelo C, Monaco A (2014) Thermal cycling for restorative materials: does a standardized protocol exist in laboratory testing? A literature review. J Mech Behav Biomed Mater 29:295\u2013308","journal-title":"J Mech Behav Biomed Mater"},{"issue":"2","key":"5891_CR43","doi-asserted-by":"publisher","first-page":"89","DOI":"10.1016\/S0300-5712(98)00037-2","volume":"27","author":"MS Gale","year":"1999","unstructured":"Gale MS, Darvell BW (1999) Thermal cycling procedures for laboratory testing of dental restorations. J Dent 27(2):89\u201399","journal-title":"J Dent"},{"issue":"6","key":"5891_CR44","doi-asserted-by":"publisher","first-page":"340","DOI":"10.1111\/j.1708-8240.2007.00134.x","volume":"19","author":"FL Amaral","year":"2007","unstructured":"Amaral FL, Colucci V, Palma-Dibb RG, Corona SA (2007) Assessment of in vitro methods used to promote adhesive interface degradation: a critical review. J Esthetic Restor Dentistry: Official Publication Am Acad Esthetic Dentistry 19(6):340\u2013353 discussion 354","journal-title":"J Esthetic Restor Dentistry: Official Publication Am Acad Esthetic Dentistry"},{"issue":"2","key":"5891_CR45","doi-asserted-by":"publisher","first-page":"107","DOI":"10.1111\/j.1708-8240.2002.tb00159.x","volume":"14","author":"AK Bedran de Castro","year":"2002","unstructured":"Bedran de Castro AK, Pimenta LA, Amaral CM, Ambrosano GM (2002) Evaluation of microleakage in cervical margins of various posterior restorative systems. J Esthetic Restor Dentistry: Official Publication Am Acad Esthetic Dentistry 14(2):107\u2013114","journal-title":"J Esthetic Restor Dentistry: Official Publication Am Acad Esthetic Dentistry"},{"issue":"3","key":"5891_CR46","first-page":"227","volume":"17","author":"K Tolidis","year":"2016","unstructured":"Tolidis K, Boutsiouki C, Gerasimou P (2016) Comparative evaluation of microleakage of a carbomer\/fluoroapatite-enhanced glass-ionomer cement on primary teeth restorations. Eur J Paediatr Dent 17(3):227\u2013233","journal-title":"Eur J Paediatr Dent"},{"key":"5891_CR47","unstructured":"Ibraheem AF, Al-Qutib TA (2006) Inhibition of artificial secondary caries by fluoride\u2013releasing restorative materials. J Baghdad Coll Dentistry 18(1)"},{"issue":"8","key":"5891_CR48","doi-asserted-by":"publisher","first-page":"1007","DOI":"10.1016\/j.jdent.2015.04.007","volume":"43","author":"AF Montagner","year":"2015","unstructured":"Montagner AF, Kuper NK, Opdam NJ, Bronkhorst EM, Cenci MS, Huysmans MC (2015) Wall-lesion development in gaps: the role of the adhesive bonding material. J Dent 43(8):1007\u20131012","journal-title":"J Dent"},{"issue":"3","key":"5891_CR49","doi-asserted-by":"publisher","first-page":"203","DOI":"10.4103\/JIOH.JIOH_297_19","volume":"12","author":"MR El-Bialy","year":"2020","unstructured":"El-Bialy MR, Shaalan OO, El-Zohairy AA, El-Zoghby AF (2020) Clinical evaluation of glass ionomer with glass hybrid technology versus conventional high viscosity glass ionomer in class I cavities in patients with high caries risk: Randomized controlled trial. J Int Oral Health 12(3):203\u2013212","journal-title":"J Int Oral Health"},{"issue":"5\u20136","key":"5891_CR50","doi-asserted-by":"publisher","first-page":"505","DOI":"10.1016\/S0300-5712(98)00008-6","volume":"26","author":"PN Pereira","year":"1998","unstructured":"Pereira PN, Inokoshi S, Tagami J (1998) In vitro secondary caries inhibition around fluoride releasing materials. J Dent 26(5\u20136):505\u2013510","journal-title":"J Dent"},{"issue":"4","key":"5891_CR51","first-page":"173","volume":"10","author":"M Nagamine","year":"1997","unstructured":"Nagamine M, Itota T, Torii Y, Irie M, Staninec M, Inoue K (1997) Effect of resin-modified glass ionomer cements on secondary caries. Am J Dent 10(4):173\u2013178","journal-title":"Am J Dent"},{"issue":"4","key":"5891_CR52","doi-asserted-by":"publisher","first-page":"1041","DOI":"10.4012\/dmj.2020-290","volume":"40","author":"M Shimizu","year":"2021","unstructured":"Shimizu M, Matsui N, Sayed M, Hamba H, Obayashi S, Takahashi M, Tsuda Y, Takagaki T, Nikaido T, Tagami J (2021) Micro-CT assessment of the effect of silver diammine fluoride on inhibition of root dentin demineralization. Dent Mater J 40(4):1041\u20131048","journal-title":"Dent Mater J"},{"issue":"2","key":"5891_CR53","doi-asserted-by":"publisher","first-page":"169","DOI":"10.4103\/JCD.JCD_300_18","volume":"22","author":"Z Abedian","year":"2019","unstructured":"Abedian Z, Jenabian N, Moghadamnia AA, Zabihi E, Tashakorian H, Rajabnia M, Sadighian F, Bijani A (2019) Antibacterial activity of high-molecular-weight and low-molecular-weight chitosan upon oral pathogens. J Conservative Dentistry: JCD 22(2):169\u2013174","journal-title":"J Conservative Dentistry: JCD"},{"issue":"2","key":"5891_CR54","first-page":"93","volume":"8","author":"A Aliasghari","year":"2016","unstructured":"Aliasghari A, Rabbani Khorasgani M, Vaezifar S, Rahimi F, Younesi H, Khoroushi M (2016) Evaluation of antibacterial efficiency of Chitosan and Chitosan nanoparticles on cariogenic streptococci: an in vitro study. Iran J Microbiol 8(2):93\u2013100","journal-title":"Iran J Microbiol"},{"issue":"11","key":"5891_CR55","doi-asserted-by":"publisher","first-page":"2440","DOI":"10.1016\/j.biomaterials.2005.11.036","volume":"27","author":"Z Shi","year":"2006","unstructured":"Shi Z, Neoh KG, Kang ET, Wang W (2006) Antibacterial and mechanical properties of bone cement impregnated with chitosan nanoparticles. Biomaterials 27(11):2440\u20132449","journal-title":"Biomaterials"},{"key":"5891_CR56","first-page":"765","volume":"6","author":"JJ Wang","year":"2011","unstructured":"Wang JJ, Zeng ZW, Xiao RZ, Xie T, Zhou GL, Zhan XR, Wang SL (2011) Recent advances of chitosan nanoparticles as drug carriers. Int J Nanomed 6:765\u2013774","journal-title":"Int J Nanomed"},{"issue":"3","key":"5891_CR57","doi-asserted-by":"publisher","first-page":"203","DOI":"10.17796\/jcpd.28.3.w0610427l746j34n","volume":"28","author":"J Hicks","year":"2004","unstructured":"Hicks J, Garcia-Godoy F, Flaitz C (2004) Biological factors in dental caries: role of remineralization and fluoride in the dynamic process of demineralization and remineralization (part 3). J Clin Pediatr Dent 28(3):203\u2013214","journal-title":"J Clin Pediatr Dent"},{"key":"5891_CR58","doi-asserted-by":"crossref","unstructured":"Sidhu SK, Nicholson JW (2016) A review of Glass-Ionomer cements for Clinical Dentistry. J Funct Biomater 7(3)","DOI":"10.3390\/jfb7030016"},{"issue":"5","key":"5891_CR59","doi-asserted-by":"publisher","first-page":"363","DOI":"10.1016\/j.prosdent.2013.06.011","volume":"110","author":"GY Lai","year":"2013","unstructured":"Lai GY, Zhu LK, Li MY, Wang J (2013) An in vitro study on the secondary caries-prevention properties of three restorative materials. J Prosthet Dent 110(5):363\u2013368","journal-title":"J Prosthet Dent"}],"container-title":["Clinical Oral Investigations"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00784-024-05891-0.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s00784-024-05891-0\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00784-024-05891-0.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,9,19]],"date-time":"2024-09-19T11:00:12Z","timestamp":1726743612000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s00784-024-05891-0"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,8,28]]},"references-count":59,"journal-issue":{"issue":"9","published-online":{"date-parts":[[2024,9]]}},"alternative-id":["5891"],"URL":"https:\/\/doi.org\/10.1007\/s00784-024-05891-0","relation":{},"ISSN":["1436-3771"],"issn-type":[{"value":"1436-3771","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,8,28]]},"assertion":[{"value":"16 May 2024","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"17 August 2024","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"28 August 2024","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"The research was approved by the Gazi University Faculty of Dentistry Clinical Research Ethics Committee (ethical protocol no. 2020.05\/4).","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethical approval"}},{"value":"The authors declare no competing interests.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}}],"article-number":"504"}}