{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,16]],"date-time":"2026-10-16T23:47:10Z","timestamp":1792194430079,"version":"4.4.0"},"reference-count":52,"publisher":"Springer Science and Business Media LLC","issue":"5","license":[{"start":{"date-parts":[[2025,4,8]],"date-time":"2025-04-08T00:00:00Z","timestamp":1744070400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"},{"start":{"date-parts":[[2025,4,8]],"date-time":"2025-04-08T00:00:00Z","timestamp":1744070400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"}],"funder":[{"name":"SSO"},{"DOI":"10.13039\/501100006447","name":"University of Zurich","doi-asserted-by":"crossref","id":[{"id":"10.13039\/501100006447","id-type":"DOI","asserted-by":"crossref"}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Clin Oral Invest"],"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Objectives<\/jats:title>\n                    <jats:p>To compare radiographic and profilometric outcomes 6\u00a0months after simultaneous lateral guided bone regeneration (GBR) at single peri-implant dehiscence defects in the anterior region using either resorbable or non-resorbable membranes.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Materials and methods<\/jats:title>\n                    <jats:p>In 27 patients with a single tooth gap in the anterior region (second premolar to second premolar in the maxilla) a dental implant was placed. Following implant placement GBR was performed at the buccal aspect using randomly either a resorbable collagen membrane (RES) or a non-resorbable titanium-reinforced ePTFE membrane (N-RES). Radiographic (cone-beam computed tomography; CBCT) measurements were performed to assess the buccal bone thickness immediately after the implant placement with simultaneous GBR (baseline) and 6\u00a0months later. Buccal soft tissue thickness was assessed by superimposing surface scans taken at baseline and again 6\u00a0months later.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      A total of 25 datasets could be assessed for the bone dimensions (\n                      <jats:italic>n<\/jats:italic>\n                      \u2009=\u200912, RES;\n                      <jats:italic>n<\/jats:italic>\n                      \u2009=\u200913, N-RES) and 14 datasets for profilometric changes (\n                      <jats:italic>n<\/jats:italic>\n                      \u2009=\u20097, RES;\n                      <jats:italic>n<\/jats:italic>\n                      \u2009=\u20097, N-RES). Group RES showed a significant mean reduction in buccal bone between baseline and 6\u00a0months of 0.8\u2009\u00b1\u20090.4\u00a0mm (\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.004). The respective mean reduction for group N-RES amounted to 0.1\u2009\u00b1\u20090.4\u00a0mm (\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.581). When comparing the buccal bone changes between both group over time, group RES exhibited greater reduction in comparison to group N-RES (intergroup\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.017). Profilometric analyses showed a non-significant trend towards soft tissue gain in group RES 0.6\u2009\u00b1\u20090.7\u00a0mm (\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.125). Conversely, N-RES group revealed stability, with a mean change of 0.0\u2009\u00b1\u20090.3\u00a0mm (\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20091.000).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>GBR using non-resorbable membranes seems to provide greater dimensional stability of augmented bone at 6\u00a0months re-entry and before implant loading compared to resorbable membranes. The lack of differences in the profilometric outcomes and contour changes may be explained by a partial compensation through an increase in soft tissue thickness with resorbable membranes.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Clinical relevance<\/jats:title>\n                    <jats:p>GBR using non-resorbable membranes may offer greater dimensional stability of augmented bone compared to resorbable membranes. However, these potential benefits may be offset by a compensatory increase in soft tissue thickness when using resorbable membranes.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1007\/s00784-025-06322-4","type":"journal-article","created":{"date-parts":[[2025,4,8]],"date-time":"2025-04-08T17:46:54Z","timestamp":1744134414000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":8,"title":["Hard and soft tissue contour changes following simultaneous guided bone regeneration at single peri-implant dehiscence defects using either resorbable or non-resorbable membranes: a 6-month secondary analysis of a randomized controlled trial"],"prefix":"10.1007","volume":"29","author":[{"given":"Franz J.","family":"Strauss","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"David","family":"Schneider","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ronald E.","family":"Jung","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Riccardo","family":"Kraus","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Daniel S.","family":"Thoma","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nadja","family":"Naenni","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2025,4,8]]},"reference":[{"key":"6322_CR1","first-page":"1109","volume":"23","author":"MM Bornstein","year":"2008","unstructured":"Bornstein MM, Halbritter S, Harnisch H, Weber HP, Buser D (2008) A retrospective analysis of patients referred for implant placement to a specialty clinic: indications, surgical procedures, and early failures. 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