{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,17]],"date-time":"2026-08-17T15:27:23Z","timestamp":1786980443707,"version":"build-2736575974"},"reference-count":29,"publisher":"Springer Science and Business Media LLC","issue":"6","license":[{"start":{"date-parts":[[2025,6,3]],"date-time":"2025-06-03T00:00:00Z","timestamp":1748908800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"},{"start":{"date-parts":[[2025,6,3]],"date-time":"2025-06-03T00:00:00Z","timestamp":1748908800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Clin Oral Invest"],"DOI":"10.1007\/s00784-025-06400-7","type":"journal-article","created":{"date-parts":[[2025,6,2]],"date-time":"2025-06-02T19:13:45Z","timestamp":1748891625000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Performance of a novel direct-conversion intraoral sensor on the assessment of caries-like lesions \u2013 an ex-vivo comparison with conventional (scintillator-dependent) intraoral sensors"],"prefix":"10.1007","volume":"29","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-1654-5251","authenticated-orcid":false,"given":"Juliana B. Melo","family":"da Fonte","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6477-6997","authenticated-orcid":false,"given":"Daniela","family":"Pita de Melo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3107-5430","authenticated-orcid":false,"given":"Ana Paula Piovezan","family":"Fugolin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2299-5769","authenticated-orcid":false,"given":"Saulo L.","family":"Sousa Melo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2025,6,3]]},"reference":[{"key":"6400_CR1","doi-asserted-by":"publisher","first-page":"427","DOI":"10.1016\/j.cden.2021.02.002","volume":"65","author":"AF Dayo","year":"2021","unstructured":"Dayo AF, Wolff MS, Syed AZ, Mupparapu M (2021) Radiology of Dental Caries. Dent Clin North Am 65:427\u2013445","journal-title":"Dent Clin North Am"},{"key":"6400_CR2","doi-asserted-by":"publisher","first-page":"280","DOI":"10.1016\/j.prosdent.2013.07.014","volume":"111","author":"VK Kutsch","year":"2014","unstructured":"Kutsch VK (2014) Dental caries: an updated medical model of risk assessment. J Prosthet Dent 111:280\u2013285","journal-title":"J Prosthet Dent"},{"key":"6400_CR3","doi-asserted-by":"publisher","first-page":"51","DOI":"10.1016\/S0140-6736(07)60031-2","volume":"369","author":"RH Selwitz","year":"2007","unstructured":"Selwitz RH, Ismail AI, Pitts NB (2007) Dental caries. Lancet 369:51\u201359","journal-title":"Lancet"},{"key":"6400_CR4","doi-asserted-by":"publisher","first-page":"645","DOI":"10.1016\/j.jds.2022.08.006","volume":"18","author":"ZS Natto","year":"2023","unstructured":"Natto ZS, Olwi A, Abduljawad F (2023) A comparison of the horizontal and vertical bitewing images in detecting approximal caries and interdental bone loss in posterior teeth: A diagnostic accuracy randomized cross over clinical trial. J Dent Sci 18:645\u2013651","journal-title":"J Dent Sci"},{"key":"6400_CR5","doi-asserted-by":"publisher","first-page":"104145","DOI":"10.1016\/j.jdent.2022.104145","volume":"122","author":"ME Khalaf","year":"2022","unstructured":"Khalaf ME, Baghdadi MT, Faridoun AE, Alshawaf NM, Qudeimat MA (2022) Clinical extension of proximal carious lesions compared to bitewing radiographs using photostimulable phosphor plates (PSP). J Dent 122:104145","journal-title":"J Dent"},{"key":"6400_CR6","doi-asserted-by":"publisher","first-page":"20210010","DOI":"10.1259\/dmfr.20210010","volume":"50","author":"A Wenzel","year":"2021","unstructured":"Wenzel A (2021) Radiographic modalities for diagnosis of caries in a historical perspective: from film to machine-intelligence supported systems. Dentomaxillofac Radiol 50:20210010","journal-title":"Dentomaxillofac Radiol"},{"key":"6400_CR7","doi-asserted-by":"publisher","first-page":"1143","DOI":"10.1007\/s00784-022-04709-1","volume":"27","author":"G G\u00f6stemeyer","year":"2023","unstructured":"G\u00f6stemeyer G, Preus M, Elhennawy K, Schwendicke F, Paris S, Askar H (2023) Accuracy of different approaches for detecting proximal root caries lesions in vitro. Clin Oral Investig 27:1143\u20131151","journal-title":"Clin Oral Investig"},{"key":"6400_CR8","doi-asserted-by":"publisher","first-page":"608","DOI":"10.1118\/1.1561285","volume":"30","author":"E Samei","year":"2003","unstructured":"Samei E, Flynn MJ (2003) An experimental comparison of detector performance for direct and indirect digital radiography systems. Med Phys 30:608\u2013622","journal-title":"Med Phys"},{"key":"6400_CR9","doi-asserted-by":"publisher","first-page":"362","DOI":"10.1007\/s10278-006-0634-4","volume":"19","author":"T Gomi","year":"2006","unstructured":"Gomi T, Koshida K, Miyati T, Miyagawa J, Hirano H (2006) An experimental comparison of flat-panel detector performance for direct and indirect systems (initial experiences and physical evaluation). J Digit Imaging 19:362\u2013370","journal-title":"J Digit Imaging"},{"key":"6400_CR10","doi-asserted-by":"publisher","first-page":"110476","DOI":"10.1016\/j.apradiso.2022.110476","volume":"190","author":"A Yousefi","year":"2022","unstructured":"Yousefi A, Jafari H, Khorsandi M, Faezmehr A (2022) Assessment of a low-cost commercial CCD for use in X-ray imaging. Appl Radiat Isot 190:110476","journal-title":"Appl Radiat Isot"},{"key":"6400_CR11","doi-asserted-by":"publisher","first-page":"20120313","DOI":"10.1259\/dmfr.20120313","volume":"42","author":"M Bel\u00e9m","year":"2013","unstructured":"Bel\u00e9m M, Tabchoury C, Ferreira-Santos R, Groppo F, Haiter-Neto F (2013) Performance of a photostimulable storage phosphor digital system with or without the sharpen filter and cone beam CT for detecting approximal enamel subsurface demineralization. Dentomaxillofacial Radiol 42:20120313","journal-title":"Dentomaxillofacial Radiol"},{"key":"6400_CR12","doi-asserted-by":"publisher","first-page":"306","DOI":"10.1016\/j.oooo.2017.05.469","volume":"124","author":"SL Sousa Melo","year":"2017","unstructured":"Sousa Melo SL, Belem MDF, Tabchoury CPM, Haiter-Neto F (2017) Cone Beam CT and Digital Intraoral Radiography Performances in the Diagnosis of Artificially Induced Recurrent Caries-Like Lesions. Oral Surg Oral Med Oral Pathol Oral Radiol 124:306\u2013314","journal-title":"Oral Surg Oral Med Oral Pathol Oral Radiol"},{"key":"6400_CR13","doi-asserted-by":"publisher","first-page":"182","DOI":"10.1016\/j.oooo.2017.11.004","volume":"125","author":"S Countryman","year":"2018","unstructured":"Countryman S, Sousa Melo SL, Belem MD, Haiter-Neto F, Vargas MA, Allareddy V (2018) Performance of Five Different Displays in the Detection of Artificial Incipient and Recurrent Caries-Like Lesions. Oral Surg Oral Med Oral Pathol Oral Radiol 125:182\u2013191","journal-title":"Oral Surg Oral Med Oral Pathol Oral Radiol"},{"key":"6400_CR14","unstructured":"XpectVision North America. XVD2530 Intraoral Sensor. Available from: https:\/\/www.xpectvision.com\/productdetail\/zxszhkncgq48.html. Accessed April 15, 2025"},{"key":"6400_CR15","unstructured":"Dexis. DEXIS IXS Digital Intraoral Sensor \u2013 Brochure. Available from: https:\/\/catakdisdeposu.com\/wp-content\/uploads\/2023\/02\/DX00307-RevB-DEXIS-IXS-Brochure.pdf. Accessed April 15, 2025"},{"key":"6400_CR16","unstructured":"Carestream Dental. RVG 6200 Intraoral Digital Imaging System. Available from: https:\/\/www.carestreamdental.com\/en-us\/shop-online\/rvg-sensors\/rvg-6200-sensor\/. Accessed April 15, 2025"},{"key":"6400_CR17","doi-asserted-by":"publisher","first-page":"173","DOI":"10.1093\/dmfr\/twaf005","volume":"54","author":"M Jervis","year":"2025","unstructured":"Jervis M, Waid E, Melo da Fonte JB, Pita de Melo D, Replogle KJ, Sousa Melo SL (2025) Assessment of the Quality of Root Canal Fillings-An Ex-Vivo Comparison of CBCT Scans, Conventional Intraoral Sensors, and a Novel Photon-Counting Sensor. Dentomaxillofac Radiol 54:173\u2013179","journal-title":"Dentomaxillofac Radiol"},{"key":"6400_CR18","doi-asserted-by":"publisher","first-page":"20200338","DOI":"10.1259\/dmfr.20200338","volume":"50","author":"K Heck","year":"2021","unstructured":"Heck K, Litzenburger F, Ullmann V, Hoffmann L, Kunzelmann KH (2021) In vitro comparison of two types of digital X-ray sensors for proximal caries detection validated by micro-computed tomography. Dentomaxillofac Radiol 50:20200338","journal-title":"Dentomaxillofac Radiol"},{"key":"6400_CR19","doi-asserted-by":"publisher","first-page":"854","DOI":"10.3348\/kjr.2022.0377","volume":"23","author":"A Esquivel","year":"2022","unstructured":"Esquivel A, Ferrero A, Mileto A, Baffour F, Horst K, Rajiah PS, Inoue A, Leng S, McCollough C, Fletcher JG (2022) Photon-Counting Detector CT: Key Points Radiologists Should Know. Korean J Radiol 23:854\u2013865","journal-title":"Korean J Radiol"},{"key":"6400_CR20","doi-asserted-by":"publisher","first-page":"729","DOI":"10.1148\/rg.2019180115","volume":"39","author":"S Leng","year":"2019","unstructured":"Leng S, Bruesewitz M, Tao S, Rajendran K, Halaweish AF, Campeau NG, Fletcher JG, McCollough CH (2019) Photon-counting Detector CT: System Design and Clinical Applications of an Emerging Technology. Radiographics 39:729\u2013743","journal-title":"Radiographics"},{"key":"6400_CR21","doi-asserted-by":"publisher","first-page":"e220158","DOI":"10.1148\/rg.220158","volume":"43","author":"AK Nehra","year":"2023","unstructured":"Nehra AK, Rajendran K, Baffour FI, Mileto A, Rajiah PS, Horst KK, Inoue A, Johnson TF, Diehn FE, Glazebrook KN, Thorne JE, Weber NM, Shanblatt ER, Gong H, Yu L, Leng S, McCollough CH, Fletcher JG (2023) Seeing More with Less: Clinical Benefits of Photon-counting Detector CT. Radiographics 43:e220158","journal-title":"Radiographics"},{"key":"6400_CR22","doi-asserted-by":"publisher","first-page":"6266","DOI":"10.1038\/s41598-023-33322-9","volume":"13","author":"RC Fontenele","year":"2023","unstructured":"Fontenele RC, Picoli FF, Pinto JC, Coudyzer W, de Faria VK, Farias Gomes A et al (2023) Feasibility of photon-counting computed tomography as a novel imaging modality for challenging endodontic diagnostic tasks. Sci Rep 13:6266","journal-title":"Sci Rep"},{"key":"6400_CR23","doi-asserted-by":"publisher","unstructured":"Kim J, Park S, Hegazy M, Lee S (2013) Comparison of a photon-counting-detector and a CMOS flat-panel-detector for a micro-CT. In: 2013 IEEE Nuclear Science Symposium and Medical Imaging Conference, NSS\/MIC 2013 Article 6829119 (IEEE Nuclear Science Symposium Conference Record). Institute of Electrical and Electronics Engineers Inc. https:\/\/doi.org\/10.1109\/NSSMIC.2013.6829119","DOI":"10.1109\/NSSMIC.2013.6829119"},{"key":"6400_CR24","doi-asserted-by":"publisher","first-page":"746","DOI":"10.1016\/j.identj.2022.06.022","volume":"72","author":"MB Cabal\u00e9n","year":"2022","unstructured":"Cabal\u00e9n MB, Molina GF, Bono A, Burrow MF (2022) Nonrestorative Caries Treatment: A Systematic Review Update. Int Dent J 72:746\u2013764","journal-title":"Int Dent J"},{"key":"6400_CR25","doi-asserted-by":"publisher","first-page":"1000","DOI":"10.1016\/j.adaj.2024.09.007","volume":"155","author":"M Fontana","year":"2024","unstructured":"Fontana M, Gonzalez-Cabezas C, Tenuta LMA (2024) Evidence-based approaches and considerations for nonrestorative treatments within modern caries management: Integrating science into practice. J Am Dent Assoc 155:1000\u20131011","journal-title":"J Am Dent Assoc"},{"key":"6400_CR26","doi-asserted-by":"publisher","first-page":"419","DOI":"10.1186\/s12903-023-02954-8","volume":"23","author":"F Mosavat","year":"2023","unstructured":"Mosavat F, Ahmadi E, Amirfarhangi S, Rafeie N (2023) Evaluation of diagnostic accuracy of CBCT and intraoral radiography for proximal caries detection in the presence of different dental restoration materials. BMC Oral Health 23:419","journal-title":"BMC Oral Health"},{"key":"6400_CR27","doi-asserted-by":"publisher","first-page":"39458105","DOI":"10.1259\/dmfr\/39458105","volume":"42","author":"A Wenzel","year":"2013","unstructured":"Wenzel A, Hirsch E, Christensen J, Matzen LH, Scaf G, Frydenberg M (2013) Detection of cavitated approximal surfaces using cone beam CT and intraoral receptors. Dentomaxillofac Radiol 42:39458105","journal-title":"Dentomaxillofac Radiol"},{"key":"6400_CR28","doi-asserted-by":"publisher","first-page":"431","DOI":"10.1259\/dmfr\/94985823","volume":"39","author":"AA Pontual","year":"2010","unstructured":"Pontual AA, de Melo DP, de Almeida SM, B\u00f3scolo FN, Haiter Neto F (2010) Comparison of digital systems and conventional dental film for the detection of approximal enamel caries. Dentomaxillofac Radiol 39:431\u2013436","journal-title":"Dentomaxillofac Radiol"},{"issue":"1","key":"6400_CR29","doi-asserted-by":"publisher","first-page":"85","DOI":"10.1016\/S0196-0644(99)70422-1","volume":"33","author":"WR Mower","year":"1999","unstructured":"Mower WR (1999) Evaluating bias and variability in diagnostic test reports. Ann Emerg Med 33(1):85\u201391","journal-title":"Ann Emerg Med"}],"updated-by":[{"DOI":"10.1007\/s00784-025-06446-7","type":"correction","label":"Correction","source":"publisher","updated":{"date-parts":[[2025,6,24]],"date-time":"2025-06-24T00:00:00Z","timestamp":1750723200000}}],"container-title":["Clinical Oral Investigations"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00784-025-06400-7.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s00784-025-06400-7\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00784-025-06400-7.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,6,27]],"date-time":"2025-06-27T14:03:15Z","timestamp":1751032995000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s00784-025-06400-7"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,6,3]]},"references-count":29,"journal-issue":{"issue":"6","published-online":{"date-parts":[[2025,6]]}},"alternative-id":["6400"],"URL":"https:\/\/doi.org\/10.1007\/s00784-025-06400-7","relation":{},"ISSN":["1436-3771"],"issn-type":[{"value":"1436-3771","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,6,3]]},"assertion":[{"value":"19 March 2025","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"25 May 2025","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"3 June 2025","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"24 June 2025","order":4,"name":"change_date","label":"Change Date","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"Correction","order":5,"name":"change_type","label":"Change Type","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"A Correction to this paper has been published:","order":6,"name":"change_details","label":"Change Details","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"https:\/\/doi.org\/10.1007\/s00784-025-06446-7","URL":"https:\/\/doi.org\/10.1007\/s00784-025-06446-7","order":7,"name":"change_details","label":"Change Details","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"This ex-vivo study was reviewed and deemed exempt by our Oregon Health & Science University institutional review board (OHSU IRB# STUDY00025013).","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethical approval"}},{"value":"Not applicable.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Informed consent"}},{"value":"The authors would like to thank Xpectvision North America as the source of the direct-conversion sensor (XpectVision XVD2530 sensor for intraoral radiographs) used for the study. The authors deny any other conflicts of interest related to this study.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflicts of interest"}},{"value":"The authors declare no competing interests.","order":5,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interest"}}],"article-number":"329"}}