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Still University, Mesa"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Clin Oral Invest"],"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>This study aimed to evaluate the clinical outcomes of gingival recession Type 1 (RT1) treatment using a coronally advanced flap (CAF) alone and in combination with L-PRF at 6 months.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Materials and methods<\/jats:title>\n                    <jats:p>\n                      A total of 70 RT1 from 19 patients were included. Participants were randomly assigned to the test group (TG, CAF\u2009+\u2009L-PRF,\n                      <jats:italic>n<\/jats:italic>\n                      \u2009=\u200942) and the control group (CG) (CAF alone,\n                      <jats:italic>n<\/jats:italic>\n                      \u2009=\u200928). Clinical parameters were assessed at baseline and at 6 months: the primary outcomes were percentage of root coverage (%RC) and complete root coverage (CRC); and the secondary outcomes included mean root coverage (MRC), changes in gingival thickness (GT) and volumetric tissue gain, recession area reduction, analgesic consumption, healing quality (the Inflammatory Proliferative Remodeling [IPR] score), and patient-reported outcome measures (PROMs). Statistical analyses were performed to determine differences between groups; a random-intercept mixed-effects model was used for all site-level outcomes.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      At six months, %RC was 89.30% \u00b1 20.33% (TG) and 81.60% \u00b1 27.93% (CG) (\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&gt;\u20090.05). For the TG and CG, respectively, %CRC was 73.81% and 57.14%; the mean GT gain was 0.16\u2009\u00b1\u20090.10\u00a0mm and 0.11\u2009\u00b1\u20090.10\u00a0mm (\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.08); the mean volume gain was 1.13\u2009\u00b1\u20091.25 mm\n                      <jats:sup>3<\/jats:sup>\n                      and 0.86\u2009\u00b1\u20090.84 mm\n                      <jats:sup>3<\/jats:sup>\n                      (\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.32); the mean number of pills taken was 1.67\u2009\u00b1\u20090.98 and 2.25\u2009\u00b1\u20091.02 (\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.04); the esthetic satisfaction was 95% \u00b1 5% and 90% \u00b1 7% (\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.31); willingness to undergo the procedure again: 93% \u00b1 4% and 88% \u00b1 6% (\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.22); sensitivity reduction: 85% \u00b1 6% and 80% \u00b1 8% (\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.19). There was no statistically significant difference in healing quality and PROMs.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Both CAF alone and CAF combined with L-PRF yielded comparable clinical and volumetric outcomes in RT1 treatments. No statistically significant advantages were observed with the adjunctive use of L-PRF.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Clinical relevance<\/jats:title>\n                    <jats:p>Because CAF alone achieves high predictability for RT1 defects, the routine adjunctive use of L-PRF provides limited additional clinical benefits.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1007\/s00784-026-06899-4","type":"journal-article","created":{"date-parts":[[2026,5,7]],"date-time":"2026-05-07T11:34:39Z","timestamp":1778153679000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Treatment of gingival recession type 1 using coronally advanced flap with leucocytes-platelet rich fibrin: a randomized controlled trial"],"prefix":"10.1007","volume":"30","author":[{"given":"Nuno Bernardo Malta","family":"dos Santos","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3022-4390","authenticated-orcid":false,"given":"Gustavo Vicentis Oliveira","family":"Fernandes","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tiago","family":"Marques","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Manuel Correia","family":"Sousa","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andr\u00e9","family":"Correia","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mar\u00eda Pilar Batalla","family":"V\u00e1zquez","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Juan","family":"Blanco-Carri\u00f3n","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2026,5,7]]},"reference":[{"key":"6899_CR1","doi-asserted-by":"publisher","first-page":"9","DOI":"10.1002\/jper.18-0281","volume":"90","author":"L Chambrone","year":"2019","unstructured":"Chambrone L, Prato G (2019) Clinical insights about the evolution of root coverage procedures: the flap, the graft, and the surgery. 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