{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,14]],"date-time":"2026-08-14T07:32:50Z","timestamp":1786692770426,"version":"build-2736575974"},"reference-count":75,"publisher":"Springer Science and Business Media LLC","issue":"8","license":[{"start":{"date-parts":[[2026,7,24]],"date-time":"2026-07-24T00:00:00Z","timestamp":1784851200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"},{"start":{"date-parts":[[2026,7,24]],"date-time":"2026-07-24T00:00:00Z","timestamp":1784851200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"}],"funder":[{"name":"Universidade Estadual Paulista J\u00falio De Mesquita Filho"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Clin Oral Invest"],"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Objectives<\/jats:title>\n                    <jats:p>To investigate whether dentin pre-treatment with bioactive glass F18 suspensions modifies dentin surface characteristics and influences the bond strength of bioceramic and epoxy resin-based endodontic sealers.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Material and methods<\/jats:title>\n                    <jats:p>Extracted human root canals were treated with distilled water, PBS or Bioglass F18 suspensions (2.5%, 5%, or 10%). Dentin surface morphology and elemental composition were analyzed by scanning electron microscopy and energy-dispersive X-ray spectroscopy. Bovine dentin specimens were treated with distilled water or 5% F18 and filled with a bioceramic (Bio-C Sealer) or epoxy resin\u2013based sealer (AH Plus) for interfacial and mechanical analyses. The material\u2013dentin interface was evaluated by micro\u2013Fourier transform infrared spectroscopy after PBS immersion. Push-out and tensile bond strength tests were performed. Statistical analysis was performed using appropriate parametric or non-parametric tests according to data distribution. The level of significance was set at \u03b1\u2009=\u20090.05.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Bioglass F18 promoted the deposition of bioactive material on the dentin surface, with comparable effects observed at 5% and 10% concentrations. All F18 concentrations significantly increased the bond strength of both sealers compared with controls (\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u20090.05). In tensile testing, dentin pre-treatment with 5% F18 resulted in significantly higher bond strength (\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u20090.05). AH Plus exhibited higher bond strength than Bio-C Sealer in both mechanical tests (\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u20090.05).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>Dentin pre-treatment with Bioglass F18 enhanced dentin bioactivity and improved the sealer\u2013dentin adhesion for both Bio-C Sealer and AH Plus. The effects were concentration-dependent across different outcomes, with 5% F18 showing favorable performance in tensile bond strength and comparable behavior to 10% F18 in push-out testing.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Clinical relevance<\/jats:title>\n                    <jats:p>Dentin pre-treatment with Bioglass F18 may improve sealer\u2013dentin interfacial performance under in vitro conditions and could represent a potential adjunctive approach in root canal sealing strategies, pending further long-term and in vivo investigations.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1007\/s00784-026-07022-3","type":"journal-article","created":{"date-parts":[[2026,7,24]],"date-time":"2026-07-24T02:08:24Z","timestamp":1784858904000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Effect of dentin pre-treatment with Bioglass F18 suspensions on surface characteristics and bond strength of endodontic sealers"],"prefix":"10.1007","volume":"30","author":[{"given":"Marcela","family":"de Come Ramos","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pedro Henrique Fiorin","family":"de Souza","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fernanda Ferrari Esteves","family":"Torres","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marina Trevelin","family":"Souza","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Edgar Dutra","family":"Zanotto","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Airton Oliveira","family":"Santos-Junior","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Juliane Maria","family":"Guerreiro-Tanomaru","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2574-4706","authenticated-orcid":false,"given":"Mario","family":"Tanomaru-Filho","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2026,7,24]]},"reference":[{"key":"7022_CR1","doi-asserted-by":"publisher","first-page":"609","DOI":"10.1016\/j.tripleo.2009.05.028","volume":"108","author":"D Ricucci","year":"2009","unstructured":"Ricucci D, Lin LM, Sp\u00e5ngberg LSW (2009) Wound healing of apical tissues after root canal therapy: a long-term clinical, radiographic, and histopathologic observation study. 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