{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,14]],"date-time":"2026-09-14T10:08:59Z","timestamp":1789380539613,"version":"build-2803163510"},"reference-count":12,"publisher":"Springer Science and Business Media LLC","issue":"9","license":[{"start":{"date-parts":[[2026,8,25]],"date-time":"2026-08-25T00:00:00Z","timestamp":1787616000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"},{"start":{"date-parts":[[2026,8,25]],"date-time":"2026-08-25T00:00:00Z","timestamp":1787616000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"}],"funder":[{"DOI":"10.13039\/501100005639","name":"Universidade De S\u00e3o Paulo","doi-asserted-by":"crossref","id":[{"id":"10.13039\/501100005639","id-type":"DOI","asserted-by":"crossref"}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Clin Oral Invest"],"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Objectives<\/jats:title>\n                    <jats:p>To evaluate whether the Optipen optical reflectometer can detect enamel surface changes associated with erosion under clinical conditions.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Materials and methods<\/jats:title>\n                    <jats:p>In this short-term parallel randomized clinical trial, 24 healthy participants were allocated to two groups: Test (T-rinse with a cola beverage for 30\u00a0s) and Control (C-rinse with water). Surface reflectance was measured using the Optipen optical reflectometer on the maxillary central incisors at baseline, immediately after rinsing, and after 2\u00a0h of salivary exposure, and expressed as the percentage of surface reflection intensity.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      The test group showed significantly lower reflectance values immediately after the erosive challenge (65.4) compared with the control group (102) (\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u20090.05). After 2\u00a0h of salivary exposure, no significant differences were observed between groups (T\u2009=\u200985.7 and C\u2009=\u200997.8).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>The Optipen optical reflectometer detected immediate changes in enamel surface reflectance in vivo following a single erosive challenge.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Clinical relevance<\/jats:title>\n                    <jats:p>This device may be useful for detecting immediate enamel surface changes following erosion. Further studies are needed to optimize reflectance measurements after salivary exposure.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1007\/s00784-026-07100-6","type":"journal-article","created":{"date-parts":[[2026,8,25]],"date-time":"2026-08-25T09:12:04Z","timestamp":1787649124000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["In vivo assessment of the Optipen optical reflectometer for detecting enamel surface changes following an erosive challenge"],"prefix":"10.1007","volume":"30","author":[{"given":"Ana Luiza Bogaz","family":"Debortolli","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Franciny Querobim","family":"Ionta","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ana Laura Marques","family":"Xavier","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Carolina Ruis","family":"Ferrari","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Thiago Saads","family":"Carvalho","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Adrian","family":"Lussi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mar\u00edlia Afonso Rabello","family":"Buzalaf","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Daniela","family":"Rios","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2026,8,25]]},"reference":[{"key":"7100_CR1","doi-asserted-by":"publisher","DOI":"10.1159\/000543571","volume-title":"Erosive tooth wear: from diagnosis to therapy","author":"RP Shellis","year":"2025","unstructured":"Shellis RP, Addy M (2025) Attrition, abrasion and erosion and their interactions in tooth wear. In: Schlueter N, Ganss C, Lussi A (eds) Erosive tooth wear: from diagnosis to therapy. Karger, Basel. https:\/\/doi.org\/10.1159\/000543571"},{"key":"7100_CR2","doi-asserted-by":"publisher","first-page":"364","DOI":"10.1038\/sj.bdj.2018.167","volume":"224","author":"N Schlueter","year":"2018","unstructured":"Schlueter N, Luka B (2018) Erosive tooth wear \u2013 a review on global prevalence and on its prevalence in risk groups. Br Dent J 224:364\u2013370. https:\/\/doi.org\/10.1038\/sj.bdj.2018.167","journal-title":"Br Dent J"},{"key":"7100_CR3","doi-asserted-by":"publisher","first-page":"463","DOI":"10.1038\/s41415-023-5623-1","volume":"234","author":"S O\u2019Toole","year":"2023","unstructured":"O\u2019Toole S, Marro F, Loomans BAC, Mehta SB (2023) Monitoring of erosive tooth wear: what to use and when to use it. Br Dent J 234:463\u2013467. https:\/\/doi.org\/10.1038\/s41415-023-5623-1","journal-title":"Br Dent J"},{"key":"7100_CR4","doi-asserted-by":"publisher","first-page":"25259","DOI":"10.1038\/srep25259","volume":"6","author":"TS Carvalho","year":"2016","unstructured":"Carvalho TS, Baumann T, Lussi A (2016) A new hand-held optical reflectometer to measure enamel erosion: correlation with surface hardness and calcium release. Sci Rep 6:25259. https:\/\/doi.org\/10.1038\/srep25259","journal-title":"Sci Rep"},{"key":"7100_CR5","doi-asserted-by":"publisher","first-page":"107002","DOI":"10.1117\/1.3631791","volume":"16","author":"E Rakhmatullina","year":"2011","unstructured":"Rakhmatullina E, Bossen A, H\u00f6schele C, Wang X, Beyeler B, Meier C, Lussi A (2011) Application of the specular and diffuse reflection analysis for in vitro diagnostics of dental erosion: correlation with enamel softening, roughness, and calcium release. J Biomed Opt 16:107002. https:\/\/doi.org\/10.1117\/1.3631791","journal-title":"J Biomed Opt"},{"key":"7100_CR6","doi-asserted-by":"publisher","first-page":"105782","DOI":"10.1016\/j.jmbbm.2023.105782","volume":"141","author":"VT Pel\u00e1","year":"2023","unstructured":"Pel\u00e1 VT, Ventura TMO, Taira EA, Thomassian LTG, Brito L, Matuhara YE, Henrique-Silva F, Groisman S, Carvalho TS, Lussi A, Buzalaf MAR (2023) Use of Reflectometer Optipen to assess the preventive effect of a sugarcane cystatin on initial dental erosion in vivo. J Mech Behav Biomed Mater 141:105782. https:\/\/doi.org\/10.1016\/j.jmbbm.2023.105782","journal-title":"J Mech Behav Biomed Mater"},{"key":"7100_CR7","doi-asserted-by":"publisher","first-page":"72","DOI":"10.1111\/j.1749-6632.1993.tb18343.x","volume":"694","author":"M Navazesh","year":"1993","unstructured":"Navazesh M (1993) Methods for collecting saliva. Ann N Y Acad Sci 694:72\u201377. https:\/\/doi.org\/10.1111\/j.1749-6632.1993.tb18343.x","journal-title":"Ann N Y Acad Sci"},{"key":"7100_CR8","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1159\/000543573","volume":"33","author":"C Ganss","year":"2025","unstructured":"Ganss C, Jung K, Lussi A (2025) How to diagnose and monitor erosive tooth wear and when is it an oral disease? Monogr Oral Sci 33:1\u201318. https:\/\/doi.org\/10.1159\/000543573","journal-title":"Monogr Oral Sci"},{"key":"7100_CR9","doi-asserted-by":"publisher","first-page":"33","DOI":"10.1159\/000275571","volume":"44","author":"H Yu","year":"2010","unstructured":"Yu H, Wei M, Hildebrandt K, ten Bosch JJ, Lippert F, Mah J (2010) Effects of enamel microstructure and mineral content on the resistance to early erosive demineralization. Caries Res 44:33\u201339. https:\/\/doi.org\/10.1159\/000275571","journal-title":"Caries Res"},{"key":"7100_CR10","doi-asserted-by":"publisher","first-page":"206","DOI":"10.1159\/000360376","volume":"25","author":"M Hannig","year":"2014","unstructured":"Hannig M, Hannig C (2014) The pellicle and erosion. Monogr Oral Sci 25:206\u2013214. https:\/\/doi.org\/10.1159\/000360376","journal-title":"Monogr Oral Sci"},{"key":"7100_CR11","doi-asserted-by":"publisher","first-page":"097009","DOI":"10.1117\/1.JBO.17.9.097009","volume":"17","author":"A Lussi","year":"2012","unstructured":"Lussi A, Bossen A, H\u00f6schele C, Beyeler B, Megert B, Meier C, Rakhmatullina E (2012) Effects of enamel abrasion, salivary pellicle, and measurement angle on the optical assessment of dental erosion. J Biomed Opt 17:097009. https:\/\/doi.org\/10.1117\/1.JBO.17.9.097009","journal-title":"J Biomed Opt"},{"key":"7100_CR12","doi-asserted-by":"publisher","first-page":"11498","DOI":"10.1038\/s41598-017-11498-1","volume":"7","author":"M Mutahar","year":"2017","unstructured":"Mutahar M, Carpenter G, Bartlett D, German M, Moazzez R (2017) The presence of acquired enamel pellicle changes acid-induced erosion from dissolution to a softening process. Sci Rep 7:11498. https:\/\/doi.org\/10.1038\/s41598-017-11498-1","journal-title":"Sci Rep"}],"container-title":["Clinical Oral Investigations"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00784-026-07100-6.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s00784-026-07100-6","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00784-026-07100-6.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,9,14]],"date-time":"2026-09-14T09:49:01Z","timestamp":1789379341000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s00784-026-07100-6"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,8,25]]},"references-count":12,"journal-issue":{"issue":"9","published-online":{"date-parts":[[2026,9]]}},"alternative-id":["7100"],"URL":"https:\/\/doi.org\/10.1007\/s00784-026-07100-6","relation":{},"ISSN":["1436-3771"],"issn-type":[{"value":"1436-3771","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,8,25]]},"assertion":[{"value":"31 March 2026","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"17 August 2026","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"25 August 2026","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"All procedures performed in studies involving human participants were in accordance with the ethical standards of the institutional and\/or national research committee and with the 1964 Helsinki Declaration and its later amendments or comparable ethical standards. The study protocol was approved by the Research Ethics Committee of the Bauru School of Dentistry, University of S\u00e3o Paulo (CAAE 75102423.9.0000.5417) and registered in the Brazilian Registry of Clinical Trials (ReBEC: RBR-283VNM6).","order":1,"name":"Ethics","label":"Ethics approval","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"Informed consent was obtained from all individual participants included in the study.","order":2,"name":"Ethics","label":"Consent to participate","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"The authors declare no competing interests.","order":3,"name":"Ethics","label":"Competing interests","group":{"name":"EthicsHeading","label":"Declarations"}}],"article-number":"415"}}