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However, clinical characteristics and prognosis of this group remain poorly understood. This study examined the prevalence, clinical correlates and outcomes of paediatric OCD co-occurring with ASD (OCD\u2009+\u2009ASD) in a large clinical cohort. Data were extracted from electronic clinical records of young people aged 4\u201317\u00a0years who had attended a mental health trust in South London, United Kingdom. We identified young people with diagnoses of OCD\u2009+\u2009ASD (<jats:italic>n<\/jats:italic>\u2009=\u2009335), OCD without ASD (<jats:italic>n<\/jats:italic>\u2009=\u20091010), and ASD without OCD (<jats:italic>n<\/jats:italic>\u2009=\u20096577). 25% of youth with OCD had a diagnosis of ASD, while 5% of those with ASD had a diagnosis of OCD. At diagnosis, youth with OCD\u2009+\u2009ASD had lower psychosocial functioning scores on the clinician-rated Child Global Assessment Scale (CGAS) compared to those with either OCD or ASD. Youth with OCD\u2009+\u2009ASD were equally likely to receive CBT compared to those with OCD but were more likely to be prescribed medication and use services for longer than either comparison group. Youth with OCD\u2009+\u2009ASD showed significant improvements in functioning (CGAS scores) after service utilisation but their gains were smaller than those with OCD. OCD\u2009+\u2009ASD commonly co-occur, conferring substantial impairment, although OCD may be underdiagnosed in youth with ASD. Young people with co-occurring OCD\u2009+\u2009ASD can make significant improvements in functioning with routine clinical care but are likely to remain more impaired than typically developing youth with OCD, indicating a need for longer-term support for these young people.<\/jats:p>","DOI":"10.1007\/s00787-020-01478-8","type":"journal-article","created":{"date-parts":[[2020,2,1]],"date-time":"2020-02-01T10:02:26Z","timestamp":1580551346000},"page":"1603-1611","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":73,"title":["Co-occurring obsessive\u2013compulsive disorder and autism spectrum disorder in young people: prevalence, clinical characteristics and outcomes"],"prefix":"10.1007","volume":"29","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-1097-1137","authenticated-orcid":false,"given":"Alex F.","family":"Martin","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1006-3008","authenticated-orcid":false,"given":"Amita","family":"Jassi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3178-3920","authenticated-orcid":false,"given":"Alexis E.","family":"Cullen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Matthew","family":"Broadbent","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8061-295X","authenticated-orcid":false,"given":"Johnny","family":"Downs","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5353-5645","authenticated-orcid":false,"given":"Georgina","family":"Krebs","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2020,2,1]]},"reference":[{"issue":"12","key":"1478_CR1","doi-asserted-by":"publisher","first-page":"1595","DOI":"10.1016\/j.rasd.2013.09.006","volume":"7","author":"A Mannion","year":"2013","unstructured":"Mannion A, Leader G (2013) Comorbidity in autism spectrum disorder: a literature review. 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All projects using CRIS are reviewed and approved by a dedicated patient-led oversight committee.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethics statement"}}]}}