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Early intervention can reduce elevated anxiety symptoms. School-based interventions exist but it is unclear how effective targeted approaches are for reducing symptoms of anxiety. This review and meta-analysis aimed to determine the effectiveness of school-based indicated interventions for symptomatic children and adolescents. The study was registered with PROSPERO [CRD42018087628]. We searched MEDLINE, EMBASE, PsycINFO, and the Cochrane Library for randomised-controlled trials comparing indicated programs for child and adolescent (5\u201318\u00a0years) anxiety to active or inactive control groups. Data were extracted from papers up to December 2019. The primary outcome was efficacy (mean change in anxiety symptom scores). Sub-group and sensitivity analyses explored intervention intensity and control type. We identified 20 studies with 2076 participants. Eighteen studies were suitable for meta-analysis. A small positive effect was found for indicated programs compared to controls on self-reported anxiety symptoms at post-test (\n                    <jats:italic>g<\/jats:italic>\n                    \u2009=\u2009\u2212\u20090.28, CI\u2009=\u2009\u2212\u20090.50, \u2212\u20090.05,\n                    <jats:italic>k<\/jats:italic>\n                    \u2009=\u200918). This benefit was maintained at 6 (\n                    <jats:italic>g<\/jats:italic>\n                    \u2009=\u2009\u2212\u20090.35, CI\u2009=\u2009\u2212\u20090.58, \u2212\u20090.13,\n                    <jats:italic>k<\/jats:italic>\n                    \u2009=\u20099) and 12\u00a0months (\n                    <jats:italic>g<\/jats:italic>\n                    \u2009=\u2009\u2212\u20090.24, CI\u2009=\u2009\u2212\u20090.48, 0.00,\n                    <jats:italic>k<\/jats:italic>\n                    \u2009=\u20094). Based on two studies,\u2009&gt;\u200912\u00a0month effects were very small (\n                    <jats:italic>g<\/jats:italic>\n                    \u2009=\u2009\u2212\u20090.01, CI\u2009=\u2009\u2212\u20090.38, 0.36). No differences were found based on intervention intensity or control type. Risk of bias and variability between studies was high (\n                    <jats:italic>I<\/jats:italic>\n                    <jats:sup>2<\/jats:sup>\n                    \u2009=\u200978%). Findings show that school-based indicated programs for child and adolescent anxiety can produce small beneficial effects, enduring for up to 12\u00a0months. Future studies should include long-term diagnostic assessments.\n                  <\/jats:p>","DOI":"10.1007\/s00787-020-01564-x","type":"journal-article","created":{"date-parts":[[2020,6,13]],"date-time":"2020-06-13T05:02:42Z","timestamp":1592024562000},"page":"849-860","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":63,"title":["Indicated prevention interventions for anxiety in children and adolescents: a review and meta-analysis of school-based programs"],"prefix":"10.1007","volume":"30","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-5307-1203","authenticated-orcid":false,"given":"Siobhan","family":"Hugh-Jones","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sophie","family":"Beckett","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ella","family":"Tumelty","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pavan","family":"Mallikarjun","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2020,6,13]]},"reference":[{"key":"1564_CR1","doi-asserted-by":"publisher","first-page":"345","DOI":"10.1111\/jcpp.12381","volume":"56","author":"GV Polanczyk","year":"2015","unstructured":"Polanczyk GV, Salum GA, Sugaya LS, Caye A, Rohde LA (2015) Annual research review: a meta-analysis of the worldwide prevalence of mental disorders in children and adolescents. 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