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The aims of the current study focusing on inpatients aged\u2009&lt;\u200919\u00a0years were to assess (1) the relationship between age and body mass index (BMI; kg\/m<jats:sup>2<\/jats:sup>), BMI-centiles, BMI-standard deviation scores (BMI-SDS) and body height-SDS at referral, (2) the percentages of patients fulfilling the DSM-5 and ICD-11 weight criteria and severity categories for AN, and (3) the validity of the AN severity specifiers via analysis of both weight related data at discharge and inpatient treatment duration. The German Registry for Anorexia Nervosa encompassed complete data sets for 469 female patients (mean age\u2009=\u200915.2\u00a0years; range 8.9\u201318.9\u00a0years) with a diagnosis of AN (<jats:italic>n<\/jats:italic>\u2009=\u2009404) or atypical AN (<jats:italic>n<\/jats:italic>\u2009=\u200965), who were ascertained at 16 German child and adolescent psychiatric hospitals. BMI at referral increased up to age 15 to subsequently plateau. Approximately one tenth of all patients with AN had a BMI above the fifth centile. The ICD-11 specifier based on a BMI-centile of 0.3 for childhood and adolescent AN entailed two equally sized groups of patients. Discharge data revealed limited validity of the specifiers. Height-SDS was not correlated with age thus stunting had no impact on our data. We corroborate the evidence to use the tenth instead of the fifth BMI-centile as the weight criterion in children and adolescents. Weight criteria should not entail major diagnostic shifts during the transition from adolescence to adulthood. The severity specifiers based on BMI or BMI-centiles do not seem to have substantial clinical validity.<\/jats:p>","DOI":"10.1007\/s00787-020-01595-4","type":"journal-article","created":{"date-parts":[[2020,7,14]],"date-time":"2020-07-14T18:03:38Z","timestamp":1594749818000},"page":"1081-1094","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":30,"title":["Age dependency of body mass index distribution in childhood and adolescent inpatients with anorexia nervosa with a focus on DSM-5 and ICD-11 weight criteria and severity specifiers"],"prefix":"10.1007","volume":"30","author":[{"given":"Christian","family":"Engelhardt","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4783-6265","authenticated-orcid":false,"given":"Manuel","family":"F\u00f6cker","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Katharina","family":"B\u00fchren","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3079-7666","authenticated-orcid":false,"given":"Brigitte","family":"Dahmen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Katja","family":"Becker","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Linda","family":"Weber","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christoph U.","family":"Correll","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0270-0954","authenticated-orcid":false,"given":"Karin Maria","family":"Egberts","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Stefan","family":"Ehrlich","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Veit","family":"Roessner","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christian","family":"Fleischhaker","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3579-6200","authenticated-orcid":false,"given":"Alexander","family":"von Gontard","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Freia","family":"Hahn","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5415-8784","authenticated-orcid":false,"given":"Ekkehart","family":"Jenetzky","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michael","family":"Kaess","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1580-9991","authenticated-orcid":false,"given":"Tanja","family":"Legenbauer","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tobias J.","family":"Renner","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ulrike M. 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He has provided expert testimony for Bristol-Myers Squibb, Janssen, and Otsuka. He served on a Data Safety Monitoring Board for Boehringer-Ingelheim, Lundbeck, Rovi, Supernus, and Teva. He received royalties from UpToDate and grant support from Janssen and Takeda. He is also a shareholder of LB Pharma. Dr. Herpertz-Dahlmann and Dr Hebebrand: research grants by German Research Society (HD, JH), German Federal Ministry for Education and Research (HD, JH), EU (HD), ERA-NET (HD), Ministry of Labour, Health and Social Policies of North-Rhine-Westfalia (HD), Innovationsfond of German health insurances (JH), Christina Barz Foundation (JH) and the University Hospital of Essen (JH); speaker\u2019s fees by Ferring (HD). Platform Ern\u00e4hrung und Bewegung (JH), Novo-Nordisk (JH)). Dr. Becker has received research grants by German Research Society, German Federal Ministry for Education and Research, Philipps-University Marburg, von Behring-R\u00f6ntgen Foundation, German Ministry for Health, University Hospital Gie\u00dfen and Marburg, Rh\u00f6n Klinikum AG. She receives honorary from Georg Thieme Publisher, and received speakers\u00b4 honorary (independent lecture content) by Shire during the last 5 years. The other authors declare that they have no conflict of interest.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of interest"}}]}}