{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,9,20]],"date-time":"2025-09-20T19:16:46Z","timestamp":1758395806088},"reference-count":29,"publisher":"Springer Science and Business Media LLC","issue":"4","license":[{"start":{"date-parts":[[2014,6,6]],"date-time":"2014-06-06T00:00:00Z","timestamp":1402012800000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Med Mol Morphol"],"published-print":{"date-parts":[[2014,12]]},"DOI":"10.1007\/s00795-014-0078-8","type":"journal-article","created":{"date-parts":[[2014,6,5]],"date-time":"2014-06-05T05:38:08Z","timestamp":1401946688000},"page":"185-188","update-policy":"http:\/\/dx.doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":4,"title":["The role of hemidesmosomes and focal contacts in the skin visualized by dual-color live cell imaging"],"prefix":"10.1007","volume":"47","author":[{"given":"Toshiyuki","family":"Ozawa","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sho","family":"Hiroyasu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Daisuke","family":"Tsuruta","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2014,6,6]]},"reference":[{"key":"78_CR1","doi-asserted-by":"crossref","first-page":"5590","DOI":"10.1002\/anie.200902240","volume":"48","author":"O Shimomura","year":"2009","unstructured":"Shimomura O (2009) Discovery of green fluorescent protein (GFP) (Nobel Lecture). Angew Chem 48:5590\u20135602","journal-title":"Angew Chem"},{"key":"78_CR2","doi-asserted-by":"crossref","first-page":"229","DOI":"10.1016\/0378-1119(92)90691-H","volume":"111","author":"DC Prasher","year":"1992","unstructured":"Prasher DC, Eckenrode VK, Ward WW, Prendergast FG, Cormier MJ (1992) Primary structure of the Aequorea victoria green-fluorescent protein. Gene 111:229\u2013233","journal-title":"Gene"},{"key":"78_CR3","doi-asserted-by":"crossref","first-page":"969","DOI":"10.1083\/jcb.149.4.969","volume":"149","author":"LM Sterk","year":"2000","unstructured":"Sterk LM, Geuijen CA, Oomen LC, Calafat J, Janssen H, Sonnenberg A (2000) The tetraspan molecule CD151, a novel constituent of hemidesmosomes, associates with the integrin alpha6beta4 and may regulate the spatial organization of hemidesmosomes. J Cell Biol 149:969\u2013982","journal-title":"J Cell Biol"},{"key":"78_CR4","doi-asserted-by":"crossref","first-page":"1968","DOI":"10.2174\/092986708785132834","volume":"15","author":"D Tsuruta","year":"2008","unstructured":"Tsuruta D, Kobayashi H, Imanishi H, Sugawara K, Ishii M, Jones JC (2008) Laminin-332-integrin interaction: a target for cancer therapy? Curr Med Chem 15:1968\u20131975","journal-title":"Curr Med Chem"},{"key":"78_CR5","doi-asserted-by":"crossref","first-page":"473","DOI":"10.1111\/j.1600-0625.2008.00721.x","volume":"17","author":"K Sugawara","year":"2008","unstructured":"Sugawara K, Tsuruta D, Ishii M, Jones JC, Kobayashi H (2008) Laminin-332 and -511 in skin. Exp Dermatol 17:473\u2013480","journal-title":"Exp Dermatol"},{"key":"78_CR6","doi-asserted-by":"crossref","first-page":"1387","DOI":"10.1083\/jcb.110.4.1387","volume":"110","author":"WG Carter","year":"1990","unstructured":"Carter WG, Wayner EA, Bouchard TS, Kaur P (1990) The role of integrins alpha 2 beta 1 and alpha 3 beta 1 in cell-cell and cell-substrate adhesion of human epidermal cells. J Cell Biol 110:1387\u20131404","journal-title":"J Cell Biol"},{"key":"78_CR7","doi-asserted-by":"crossref","first-page":"122","DOI":"10.1002\/cm.10089","volume":"54","author":"D Tsuruta","year":"2003","unstructured":"Tsuruta D, Hopkinson SB, Jones JC (2003) Hemidesmosome protein dynamics in live epithelial cells. Cell Motil Cytoskelet 54:122\u2013134","journal-title":"Cell Motil Cytoskelet"},{"key":"78_CR8","doi-asserted-by":"crossref","first-page":"3845","DOI":"10.1091\/mbc.02-01-0601","volume":"13","author":"CA Geuijen","year":"2002","unstructured":"Geuijen CA, Sonnenberg A (2002) Dynamics of the alpha6beta4 integrin in keratinocytes. Mol Biol Cell 13:3845\u20133858","journal-title":"Mol Biol Cell"},{"key":"78_CR9","doi-asserted-by":"crossref","first-page":"27","DOI":"10.1007\/s00795-010-0502-7","volume":"44","author":"T Ozawa","year":"2011","unstructured":"Ozawa T, Tsuruta D (2011) Comparative study of the dynamics of focal contacts in live epithelial and mesenchymal cells. Med Mol Morphol 44:27\u201333","journal-title":"Med Mol Morphol"},{"key":"78_CR10","doi-asserted-by":"crossref","first-page":"233","DOI":"10.1111\/j.1365-2133.2008.08976.x","volume":"160","author":"JE Lai-Cheong","year":"2009","unstructured":"Lai-Cheong JE, Tanaka A, Hawche G, Emanuel P, Maari C, Taskesen M et al (2009) Kindler syndrome: a focal adhesion genodermatosis. Br J Dermatol 160:233\u2013242","journal-title":"Br J Dermatol"},{"key":"78_CR11","first-page":"1","volume":"62","author":"D Tsuruta","year":"2011","unstructured":"Tsuruta D, Hashimoto T, Hamill KJ, Jones JC (2011) Hemidesmosomes and focal contact proteins: functions and cross-talk in keratinocytes, bullous diseases and wound healing. J Dermatol Sci 62:1\u20137","journal-title":"J Dermatol Sci"},{"key":"78_CR12","doi-asserted-by":"crossref","first-page":"4977","DOI":"10.1242\/jcs.00823","volume":"116","author":"D Tsuruta","year":"2003","unstructured":"Tsuruta D, Jones JC (2003) The vimentin cytoskeleton regulates focal contact size and adhesion of endothelial cells subjected to shear stress. J Cell Sci 116:4977\u20134984","journal-title":"J Cell Sci"},{"key":"78_CR13","doi-asserted-by":"crossref","first-page":"866","DOI":"10.1096\/fj.01-0878fje","volume":"16","author":"D Tsuruta","year":"2002","unstructured":"Tsuruta D, Gonzales M, Hopkinson SB, Otey C, Khuon S, Goldman RD et al (2002) Microfilament-dependent movement of the beta3 integrin subunit within focal contacts of endothelial cells. FASEB J 16:866\u2013868","journal-title":"FASEB J"},{"key":"78_CR14","doi-asserted-by":"crossref","first-page":"673","DOI":"10.1016\/S0092-8674(02)00971-6","volume":"110","author":"RO Hynes","year":"2002","unstructured":"Hynes RO (2002) Integrins: bidirectional, allosteric signaling machines. Cell 110:673\u2013687","journal-title":"Cell"},{"key":"78_CR15","doi-asserted-by":"crossref","first-page":"1624","DOI":"10.1038\/jid.2009.439","volume":"130","author":"T Ozawa","year":"2010","unstructured":"Ozawa T, Tsuruta D, Jones JC, Ishii M, Ikeda K, Harada T et al (2010) Dynamic relationship of focal contacts and hemidesmosome protein complexes in live cells. J Invest Dermatol 130:1624\u20131635","journal-title":"J Invest Dermatol"},{"key":"78_CR16","doi-asserted-by":"crossref","first-page":"751","DOI":"10.1001\/jama.1967.03120220053008","volume":"200","author":"RE Jordon","year":"1967","unstructured":"Jordon RE, Beutner EH, Witebsky E, Blumental G, Hale WL, Lever WF (1967) Basement zone antibodies in bullous pemphigoid. JAMA 200:751\u2013756","journal-title":"JAMA"},{"key":"78_CR17","doi-asserted-by":"crossref","first-page":"1231","DOI":"10.4049\/jimmunol.136.4.1231","volume":"136","author":"RS Labib","year":"1986","unstructured":"Labib RS, Anhalt GJ, Patel HP, Mutasim DF, Diaz LA (1986) Molecular heterogeneity of the bullous pemphigoid antigens as detected by immunoblotting. J Immunol 136:1231\u20131235","journal-title":"J Immunol"},{"key":"78_CR18","doi-asserted-by":"crossref","first-page":"1088","DOI":"10.1172\/JCI114812","volume":"86","author":"LA Diaz","year":"1990","unstructured":"Diaz LA, Ratrie H 3rd, Saunders WS, Futamura S, Squiquera HL, Anhalt GJ et al (1990) Isolation of a human epidermal cDNA corresponding to the 180-kD autoantigen recognized by bullous pemphigoid and herpes gestationis sera. Immunolocalization of this protein to the hemidesmosome. J Clin Investig 86:1088\u20131094","journal-title":"J Clin Investig"},{"key":"78_CR19","doi-asserted-by":"crossref","first-page":"1864","DOI":"10.1172\/JCI113803","volume":"82","author":"JR Stanley","year":"1988","unstructured":"Stanley JR, Tanaka T, Mueller S, Klaus-Kovtun V, Roop D (1988) Isolation of complementary DNA for bullous pemphigoid antigen by use of patients\u2019 autoantibodies. J Clin Investig 82:1864\u20131870","journal-title":"J Clin Investig"},{"key":"78_CR20","doi-asserted-by":"crossref","first-page":"2480","DOI":"10.1172\/JCI116856","volume":"92","author":"Z Liu","year":"1993","unstructured":"Liu Z, Diaz LA, Troy JL, Taylor AF, Emery DJ, Fairley JA et al (1993) A passive transfer model of the organ-specific autoimmune disease, bullous pemphigoid, using antibodies generated against the hemidesmosomal antigen, BP180. J Clin Investig 92:2480\u20132488","journal-title":"J Clin Investig"},{"key":"78_CR21","doi-asserted-by":"crossref","first-page":"1539","DOI":"10.1172\/JCI117826","volume":"95","author":"Z Liu","year":"1995","unstructured":"Liu Z, Giudice GJ, Swartz SJ, Fairley JA, Till GO, Troy JL et al (1995) The role of complement in experimental bullous pemphigoid. J Clin Investig 95:1539\u20131544","journal-title":"J Clin Investig"},{"key":"78_CR22","doi-asserted-by":"crossref","first-page":"1256","DOI":"10.1172\/JCI119639","volume":"100","author":"Z Liu","year":"1997","unstructured":"Liu Z, Giudice GJ, Zhou X, Swartz SJ, Troy JL, Fairley JA et al (1997) A major role for neutrophils in experimental bullous pemphigoid. J Clin Investig 100:1256\u20131263","journal-title":"J Clin Investig"},{"key":"78_CR23","doi-asserted-by":"crossref","first-page":"3987","DOI":"10.4049\/jimmunol.169.7.3987","volume":"169","author":"R Chen","year":"2002","unstructured":"Chen R, Fairley JA, Zhao ML, Giudice GJ, Zillikens D, Diaz LA et al (2002) Macrophages, but not T and B lymphocytes, are critical for subepidermal blister formation in experimental bullous pemphigoid: macrophage-mediated neutrophil infiltration depends on mast cell activation. J Immunol 169:3987\u20133992","journal-title":"J Immunol"},{"key":"78_CR24","doi-asserted-by":"crossref","first-page":"1151","DOI":"10.1172\/JCI11494","volume":"108","author":"R Chen","year":"2001","unstructured":"Chen R, Ning G, Zhao ML, Fleming MG, Diaz LA, Werb Z et al (2001) Mast cells play a key role in neutrophil recruitment in experimental bullous pemphigoid. J Clin Investig 108:1151\u20131158","journal-title":"J Clin Investig"},{"key":"78_CR25","doi-asserted-by":"crossref","first-page":"2892","DOI":"10.1172\/JCI17891","volume":"116","author":"KC Nelson","year":"2006","unstructured":"Nelson KC, Zhao M, Schroeder PR, Li N, Wetsel RA, Diaz LA et al (2006) Role of different pathways of the complement cascade in experimental bullous pemphigoid. J Clin Investig 116:2892\u20132900","journal-title":"J Clin Investig"},{"key":"78_CR26","doi-asserted-by":"crossref","first-page":"71","DOI":"10.1046\/j.1365-2133.1998.02028.x","volume":"138","author":"Y Kitajima","year":"1998","unstructured":"Kitajima Y, Nojiri M, Yamada T, Hirako Y, Owaribe K (1998) Internalization of the 180\u00a0kDa bullous pemphigoid antigen as immune complexes in basal keratinocytes: an important early event in blister formation in bullous pemphigoid. Br J Dermatol 138:71\u201376","journal-title":"Br J Dermatol"},{"key":"78_CR27","doi-asserted-by":"crossref","first-page":"919","DOI":"10.1038\/jid.2008.305","volume":"129","author":"H Iwata","year":"2009","unstructured":"Iwata H, Kamio N, Aoyama Y, Yamamoto Y, Hirako Y, Owaribe K et al (2009) IgG from patients with bullous pemphigoid depletes cultured keratinocytes of the 180-kDa bullous pemphigoid antigen (type XVII collagen) and weakens cell attachment. J Invest Dermatol 129:919\u2013926","journal-title":"J Invest Dermatol"},{"key":"78_CR28","doi-asserted-by":"crossref","first-page":"832","DOI":"10.1016\/j.immuni.2011.09.015","volume":"35","author":"TB Feyerabend","year":"2011","unstructured":"Feyerabend TB, Weiser A, Tietz A, Stassen M, Harris N, Kopf M et al (2011) Cre-mediated cell ablation contests mast cell contribution in models of antibody- and T cell-mediated autoimmunity. Immunity 35:832\u2013844","journal-title":"Immunity"},{"key":"78_CR29","doi-asserted-by":"crossref","first-page":"828","DOI":"10.1016\/j.ajpath.2012.11.029","volume":"182","author":"S Hiroyasu","year":"2013","unstructured":"Hiroyasu S, Ozawa T, Kobayashi H, Ishii M, Aoyama Y, Kitajima Y et al (2013) Bullous pemphigoid IgG induces BP180 internalization via a macropinocytic pathway. Am J Pathol 182:828\u2013840","journal-title":"Am J Pathol"}],"container-title":["Medical Molecular Morphology"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s00795-014-0078-8.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1007\/s00795-014-0078-8\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s00795-014-0078-8","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,7,13]],"date-time":"2023-07-13T23:51:04Z","timestamp":1689292264000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/s00795-014-0078-8"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2014,6,6]]},"references-count":29,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2014,12]]}},"alternative-id":["78"],"URL":"https:\/\/doi.org\/10.1007\/s00795-014-0078-8","relation":{},"ISSN":["1860-1480","1860-1499"],"issn-type":[{"value":"1860-1480","type":"print"},{"value":"1860-1499","type":"electronic"}],"subject":[],"published":{"date-parts":[[2014,6,6]]}}}