{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,1]],"date-time":"2025-11-01T18:35:30Z","timestamp":1762022130058,"version":"build-2065373602"},"reference-count":23,"publisher":"Springer Science and Business Media LLC","issue":"4","license":[{"start":{"date-parts":[[2020,4,6]],"date-time":"2020-04-06T00:00:00Z","timestamp":1586131200000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"},{"start":{"date-parts":[[2020,4,6]],"date-time":"2020-04-06T00:00:00Z","timestamp":1586131200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Med Mol Morphol"],"published-print":{"date-parts":[[2020,12]]},"DOI":"10.1007\/s00795-020-00250-w","type":"journal-article","created":{"date-parts":[[2020,4,6]],"date-time":"2020-04-06T10:02:46Z","timestamp":1586167366000},"page":"238-243","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":8,"title":["Chronic stress-induced elevation of IL-1\u03b2 in the saliva and submandibular glands of mice"],"prefix":"10.1007","volume":"53","author":[{"given":"Durga","family":"Paudel","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tetsuro","family":"Morikawa","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Koki","family":"Yoshida","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Osamu","family":"Uehara","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sarita","family":"Giri","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Puja","family":"Neopane","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ariuntsetseg","family":"Khurelchuluun","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Daichi","family":"Hiraki","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jun","family":"Sato","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yoshihiro","family":"Abiko","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2020,4,6]]},"reference":[{"key":"250_CR1","doi-asserted-by":"publisher","first-page":"141","DOI":"10.1016\/S1079-2104(96)80403-3","volume":"81","author":"JA Ship","year":"1996","unstructured":"Ship JA, Mich AA (1996) Recurrent aphthous stomatitis: an update. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 81:141\u2013147","journal-title":"Oral Surg Oral Med Oral Pathol Oral Radiol Endod"},{"key":"250_CR2","doi-asserted-by":"publisher","first-page":"298","DOI":"10.1034\/j.1601-0825.2003.00960.x","volume":"9","author":"M Koray","year":"2003","unstructured":"Koray M, D\u00fclger O, Ak G, Horasanli S, U\u00e7ok A, Tanyeri H, Badur S (2003) The evaluation of anxiety and salivary cortisol levels in patients with oral lichen planus. Oral Dis 9:298\u2013301","journal-title":"Oral Dis"},{"key":"250_CR3","doi-asserted-by":"publisher","DOI":"10.1186\/s13030-016-0068-2","author":"A Toyofuku","year":"2016","unstructured":"Toyofuku A (2016) Psychosomatic problems in dentistry. BioPsychoSocial Med. https:\/\/doi.org\/10.1186\/s13030-016-0068-2","journal-title":"BioPsychoSocial Med"},{"key":"250_CR4","doi-asserted-by":"publisher","DOI":"10.1155\/2012\/518548","author":"Y Abiko","year":"2012","unstructured":"Abiko Y, Matsuoka H, Chiba I, Toyofuku A (2012) Current evidence on atypical odontalgia: diagnosis and clinical management. Int J Dent. https:\/\/doi.org\/10.1155\/2012\/518548","journal-title":"Int J Dent"},{"key":"250_CR5","doi-asserted-by":"publisher","first-page":"316","DOI":"10.3389\/fnhum.2017.00316","volume":"11","author":"YZ Liu","year":"2017","unstructured":"Liu YZ, Wang YX, Jiang CL (2017) Inflammation: the common pathway of stress-related diseases. Front Hum Neurosci 11:316. https:\/\/doi.org\/10.3389\/fnhum.2017.00316","journal-title":"Front Hum Neurosci"},{"key":"250_CR6","doi-asserted-by":"publisher","DOI":"10.1155\/2014\/780616","author":"R Tian","year":"2014","unstructured":"Tian R, Hou G, Li D, Yuan T-F (2014) A possible change process of inflammatory cytokines in the prolonged chronic stress and its ultimate implications for health. Sci World J. https:\/\/doi.org\/10.1155\/2014\/780616","journal-title":"Sci World J"},{"key":"250_CR7","doi-asserted-by":"publisher","first-page":"e82","DOI":"10.1590\/1807-3107bor-2018.vol32.0082","volume":"32","author":"JSM Humberto","year":"2018","unstructured":"Humberto JSM, Pavanin JV, Rocha MJAD, Motta ACF (2018) Cytokines, cortisol, and nitric oxide as salivary biomarkers in oral lichen planus: a systematic review. Braz Oral Res 32:e82. https:\/\/doi.org\/10.1590\/1807-3107bor-2018.vol32.0082","journal-title":"Braz Oral Res"},{"key":"250_CR8","doi-asserted-by":"publisher","first-page":"e33","DOI":"10.4317\/medoral.16.e33","volume":"16","author":"A Eguia-del Valle","year":"2011","unstructured":"Eguia-del Valle A, Martinez-Conde-Llamosas R, Lopez-Vicente J, Uribarri-Etxebarria A, Aguirre-Urizar JM (2011) Salivary levels of tumour necrosis factor-alpha in patients with recurrent aphthous stomatitis. Med Oral Patol Oral Cir Bucal 16:e33\u2013e36. https:\/\/doi.org\/10.4317\/medoral.16.e33","journal-title":"Med Oral Patol Oral Cir Bucal"},{"key":"250_CR9","doi-asserted-by":"publisher","first-page":"1586","DOI":"10.1177\/0333102419854052","volume":"39","author":"J Kishore","year":"2019","unstructured":"Kishore J, Shaikh F, Mirza S, Raffat MA, Ikram S, Akram Z (2019) Cytokine levels and their role in the etiopathogenesis of burning mouth syndrome: a systematic review. Cephalalgia 39:1586\u20131594","journal-title":"Cephalalgia"},{"key":"250_CR10","first-page":"1375","volume":"18","author":"M Yisireyili","year":"2019","unstructured":"Yisireyili M, Wulamu W, Aili A, Li Y, Alimujiang A, Aipire A, Aizezi M, Zhang W, Cao Z, Mijiti A, Abudureyimu K (2019) Chronic restraint stress induces esophageal fibrosis with enhanced oxidative stress in a murine model. Exp Ther Med 18:1375\u20131383","journal-title":"Exp Ther Med"},{"key":"250_CR11","doi-asserted-by":"publisher","first-page":"402","DOI":"10.1006\/meth.2001.1262","volume":"25","author":"KJ Livak","year":"2001","unstructured":"Livak KJ, Schmittgen TD (2001) Analysis of relative gene expression data using real-time quantitative PCR and the 2(-delta delta C(T)) method. Methods 25:402\u2013408","journal-title":"Methods"},{"key":"250_CR12","doi-asserted-by":"publisher","first-page":"253","DOI":"10.1016\/j.bbi.2014.08.008","volume":"44","author":"DC Slavish","year":"2015","unstructured":"Slavish DC, Graham-Engeland JE, Smyth JM, Engeland CG (2015) Salivary markers of inflammation in response to acute stress. Brain Behav Immun 44:253\u2013269","journal-title":"Brain Behav Immun"},{"key":"250_CR13","doi-asserted-by":"publisher","first-page":"294","DOI":"10.1093\/rheumatology\/keh058","volume":"43","author":"J Hernandez-Rodriguez","year":"2004","unstructured":"Hernandez-Rodriguez J, Segarra M, Vilardell C, Sanchez M, Garcia-Martinez A, Esteban MJ, Queralt C, Grau JM, Urbano-Marquez A, Palacin A, Colomer D, Cid MC (2004) Tissue production of pro-inflammatory cytokines (IL-1\u03b2, TNF-\u03b1 and IL-6) correlates with the intensity of the systemic inflammatory response and with corticosteroid requirements in giant-cell arteritis. Rheumatology 43:294\u2013301","journal-title":"Rheumatology"},{"key":"250_CR14","doi-asserted-by":"publisher","first-page":"290","DOI":"10.1111\/j.1749-6632.2002.tb04229.x","volume":"966","author":"IJ Elenkov","year":"2002","unstructured":"Elenkov IJ, Chrousos GP (2002) Stress hormones, proinflammatory and antiinflammatory cytokines, and autoimmunity. Ann N Y Acad Sci 966:290\u2013303","journal-title":"Ann N Y Acad Sci"},{"key":"250_CR15","doi-asserted-by":"publisher","first-page":"797","DOI":"10.1016\/j.archoralbio.2009.05.007","volume":"54","author":"KI Suh","year":"2009","unstructured":"Suh KI, Kim YK, Kho HS (2009) Salivary levels of IL-1\u03b2, IL-6, IL-8, and TNF-\u03b1 in patients with burning mouth syndrome. Arch Oral Biol 54:797\u2013802","journal-title":"Arch Oral Biol"},{"key":"250_CR16","doi-asserted-by":"publisher","first-page":"269","DOI":"10.1111\/j.1600-0714.2008.00734.x","volume":"38","author":"FN Pekiner","year":"2009","unstructured":"Pekiner FN, G\u00fcmr\u00fc B, Demirel GY, \u00d6zbayrak S (2009) Burning mouth syndrome and saliva: detection of salivary trace elements and cytokines. J Oral Pathol Med 38:269\u2013275","journal-title":"J Oral Pathol Med"},{"key":"250_CR17","doi-asserted-by":"publisher","first-page":"250","DOI":"10.1159\/000367714","volume":"22","author":"FCT De Souza","year":"2014","unstructured":"De Souza FCT, Kummer A, Silva ML, Amaral TM, Abdo EN, Abreu MH, Silva TA, Teixeira AL (2014) The association of openness personality trait with stress-related salivary biomarkers in burning mouth syndrome. NeuroImmunoModulation 22:250\u2013255","journal-title":"NeuroImmunoModulation"},{"key":"250_CR18","doi-asserted-by":"publisher","first-page":"54632","DOI":"10.1155\/MI\/2006\/54632","volume":"1","author":"D Simci\u0107","year":"2006","unstructured":"Simci\u0107 D, Pezelj-Ribari\u0107 S, Grzi\u0107 R, Horvat J, Brumini G, Muhvi\u0107-Urek M (2006) Detection of salivary interleukin 2 and interleukin 6 in patients with burning mouth syndrome. Mediators Inflamm 1:54632. https:\/\/doi.org\/10.1155\/MI\/2006\/54632","journal-title":"Mediators Inflamm"},{"key":"250_CR19","doi-asserted-by":"publisher","first-page":"77","DOI":"10.1002\/mc.20113","volume":"44","author":"NL Rhodus","year":"2005","unstructured":"Rhodus NL, Cheng B, Myers S, Miller L, Ho V, Ondrey F (2005) The feasibility of monitoring NF-kappaB associated cytokines: TNF-alpha, IL-1alpha, IL-6, and IL-8 in whole saliva for the malignant transformation of oral lichen planus. Mol Carcinog 44:77\u201382","journal-title":"Mol Carcinog"},{"key":"250_CR20","doi-asserted-by":"publisher","first-page":"144","DOI":"10.1016\/j.cyto.2007.11.004","volume":"41","author":"Y Zhang","year":"2008","unstructured":"Zhang Y, Lin M, Zhang S, Wang Z, Jiang L, Shen J, Bai J, Gao F, Zhou M, Chen Q (2008) NF-kappaB-dependent cytokines in saliva and serum from patients with oral lichen planus: a study in an ethnic Chinese population. Cytokine 41:144\u2013149","journal-title":"Cytokine"},{"key":"250_CR21","doi-asserted-by":"publisher","first-page":"956","DOI":"10.1902\/jop.2013.130320","volume":"85","author":"Y-SL Cheng","year":"2014","unstructured":"Cheng Y-SL, Jordan L, Gorugantula LM, Schneiderman ED, Chen HS, Rees T (2014) Salivary interleukin-6 and -8 in patients with oral cancer and patients with chronic oral inflammatory diseases. J Periodontol 85:956\u2013965","journal-title":"J Periodontol"},{"key":"250_CR22","doi-asserted-by":"publisher","first-page":"734","DOI":"10.1111\/jop.12199","volume":"43","author":"A Abdel-Haq","year":"2014","unstructured":"Abdel-Haq A, Kusnierz-Cabala B, Darczuk D, Sobuta E, Dumnicka P, Chomyszyn-Gajewska W-P (2014) Interleukin-6 and neopterin levels in the serum and saliva of patients with Lichen planus and oral Lichen planus. J Oral Pathol Med 43:734\u2013739","journal-title":"J Oral Pathol Med"},{"key":"250_CR23","first-page":"319","volume":"47","author":"SH Jeong","year":"2016","unstructured":"Jeong SH, Na HS, Park SH, Ahn YW, Chung J (2016) Topical sulfasalazine for unresponsive oral lichen planus. Quintessence Int 47:319\u2013327","journal-title":"Quintessence Int"}],"container-title":["Medical Molecular Morphology"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s00795-020-00250-w.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1007\/s00795-020-00250-w\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s00795-020-00250-w.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,4,5]],"date-time":"2021-04-05T23:43:18Z","timestamp":1617666198000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/s00795-020-00250-w"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,4,6]]},"references-count":23,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2020,12]]}},"alternative-id":["250"],"URL":"https:\/\/doi.org\/10.1007\/s00795-020-00250-w","relation":{},"ISSN":["1860-1480","1860-1499"],"issn-type":[{"type":"print","value":"1860-1480"},{"type":"electronic","value":"1860-1499"}],"subject":[],"published":{"date-parts":[[2020,4,6]]},"assertion":[{"value":"18 February 2020","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"27 March 2020","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"6 April 2020","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Compliance with ethical standards"}},{"value":"The authors declare that they have no conflicts of interest.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of interest"}}]}}