{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,27]],"date-time":"2026-09-27T14:18:52Z","timestamp":1790518732755,"version":"4.1.0"},"reference-count":29,"publisher":"Springer Science and Business Media LLC","issue":"11","license":[{"start":{"date-parts":[[2007,8,23]],"date-time":"2007-08-23T00:00:00Z","timestamp":1187827200000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J Mol Model"],"published-print":{"date-parts":[[2007,9,14]]},"DOI":"10.1007\/s00894-007-0232-5","type":"journal-article","created":{"date-parts":[[2007,8,22]],"date-time":"2007-08-22T08:53:55Z","timestamp":1187772835000},"page":"1133-1139","source":"Crossref","is-referenced-by-count":4,"title":["The studies on substrate, product and inhibitor binding to a wild-type and neuronopathic form of human acid-\u03b2-glucosidase"],"prefix":"10.1007","volume":"13","author":[{"given":"Igor Z.","family":"Zubrzycki","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Agnieszka","family":"Borcz","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Magdalena","family":"Wiacek","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wojciech","family":"Hagner","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2007,8,23]]},"reference":[{"key":"232_CR1","doi-asserted-by":"crossref","first-page":"14319","DOI":"10.1016\/S0021-9258(17)38720-3","volume":"260","author":"AH Erickson","year":"1985","unstructured":"Erickson AH, Ginns EI, Barranger JA (1985) J Biol Chem 260:14319\u201314324","journal-title":"J Biol Chem"},{"key":"232_CR2","first-page":"3","volume-title":"Carbohydrate-active enzymes: an integrated database approach","author":"PM Coutinho","year":"1999","unstructured":"Coutinho PM, Henrissat B (1999) Carbohydrate-active enzymes: an integrated database approach. The Royal Society of Chemistry, Cambridge, pp 3\u201312"},{"key":"232_CR3","first-page":"741","volume":"44","author":"JE Bergmann","year":"1989","unstructured":"Bergmann JE, Grabowski GA (1989) Am J Hum Genet 44:741\u2013750","journal-title":"Am J Hum Genet"},{"key":"232_CR4","doi-asserted-by":"crossref","first-page":"2283","DOI":"10.1016\/S0021-9258(17)42166-1","volume":"269","author":"ME Grace","year":"1994","unstructured":"Grace ME, Newman KM, Scheinker V, Berg-Fussman A, Grabowski GA (1994) J Biol Chem 269:2283\u20132291","journal-title":"J Biol Chem"},{"key":"232_CR5","doi-asserted-by":"crossref","first-page":"15428","DOI":"10.1073\/pnas.192582899","volume":"99","author":"AR Sawkar","year":"2002","unstructured":"Sawkar AR, Cheng WC, Beutler E, Wong CH, Balch WE, Kelly JW (2002) Proc Natl Acad Sci (USA) 99:15428\u201315433","journal-title":"Proc Natl Acad Sci (USA)"},{"key":"232_CR6","volume-title":"Glucosylceramide Lipidoses: Gaucher Disease","author":"JA Barranger","year":"1989","unstructured":"Barranger JA, Ginns EI (1989) Glucosylceramide Lipidoses: Gaucher Disease, 6th ed. McGraw Hill Inc., New York","edition":"6"},{"key":"232_CR7","doi-asserted-by":"crossref","first-page":"10112","DOI":"10.1016\/S0021-9258(18)90936-1","volume":"259","author":"S Takasaki","year":"1984","unstructured":"Takasaki S, Murray GJ, Furbisch FS, Brady RO, Baranger JA, Kobata A (1984) J Biol Chem 259:10112\u201310117","journal-title":"J Biol Chem"},{"key":"232_CR8","doi-asserted-by":"crossref","first-page":"14861","DOI":"10.1016\/S0021-9258(18)82412-7","volume":"268","author":"A Berg-Fussman","year":"1993","unstructured":"Berg-Fussman A, Grace ME, Grabowski GA (1993) J Biol Chem 268:14861\u201314866","journal-title":"J Biol Chem"},{"key":"232_CR9","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1002\/humu.1380030102","volume":"3","author":"M Horowitz","year":"1994","unstructured":"Horowitz M, Zimran A (1994) Hum Mutat 3:1\u201311","journal-title":"Hum Mutat"},{"key":"232_CR10","doi-asserted-by":"crossref","first-page":"151","DOI":"10.1051\/jbio\/2002196020151","volume":"196","author":"S Fabrega","year":"2002","unstructured":"Fabrega S, Durand P, Mornon J-P, Lehn P (2002) J Soc Biol 196:151\u2013160","journal-title":"J Soc Biol"},{"key":"232_CR11","doi-asserted-by":"crossref","first-page":"10975","DOI":"10.1016\/S0021-9258(19)78077-6","volume":"269","author":"S Miao","year":"1994","unstructured":"Miao S, McCarter JD, Grace ME, Grabowski GA, Aebersold R, Withers SG (1994) J Biol Chem 269:10975\u201310978","journal-title":"J Biol Chem"},{"key":"232_CR12","doi-asserted-by":"crossref","first-page":"1217","DOI":"10.1093\/glycob\/10.11.1217","volume":"10","author":"S Fabrega","year":"2000","unstructured":"Fabrega S, Durand P, Codogno P, Bauvy C, Delomenie C, Henrissat B, Martin BM, McKinney C, Ginns EI, Mornon JP, Lehn P (2000) Glycobiology 10:1217\u20131224","journal-title":"Glycobiology"},{"key":"232_CR13","doi-asserted-by":"crossref","first-page":"704","DOI":"10.1038\/sj.embor.embor873","volume":"4","author":"H Dvir","year":"2003","unstructured":"Dvir H, Harel M, McCarthy AA, Toker L, Silman I, Futerman AH, Sussman JL (2003) EMBO Rep 4:704\u2013709","journal-title":"EMBO Rep"},{"key":"232_CR14","doi-asserted-by":"crossref","first-page":"23815","DOI":"10.1074\/jbc.M502799200","volume":"280","author":"L Premkumar","year":"2005","unstructured":"Premkumar L, Sawkar AR, Boldin-Adamsky S, Toker L, Silman I, Kelly JW, Futerman AH, Sussman JL (2005) J Biol Chem 280:23815\u201323819","journal-title":"J Biol Chem"},{"key":"232_CR15","first-page":"982","volume":"55","author":"N Morel","year":"1999","unstructured":"Morel N, Bon S, Greenblatt H, Wodak S, Sussman JL, Massoulie J, Silman I (1999) Mol Parmacol 55:982\u2013992","journal-title":"Mol Parmacol"},{"key":"232_CR16","doi-asserted-by":"crossref","first-page":"2714","DOI":"10.1002\/elps.1150181505","volume":"18","author":"N Guex","year":"1997","unstructured":"Guex N, Peitsch MC (1997) Electrophoresis 18:2714\u20132723","journal-title":"Electrophoresis"},{"key":"232_CR17","volume-title":"Intramolecular Forces, D","author":"HJ Berendsen","year":"1981","unstructured":"Berendsen HJ, Postma JP, van Gunsteren WF, Hermans J (1981) Intramolecular Forces, D. Reidel Publishing Company, Dordrecht"},{"key":"232_CR18","doi-asserted-by":"crossref","first-page":"2906","DOI":"10.1016\/S0006-3495(02)75631-2","volume":"82","author":"IZ Zubrzycki","year":"2002","unstructured":"Zubrzycki IZ (2002) Biophys J 82:2906\u20132915","journal-title":"Biophys J"},{"key":"232_CR19","doi-asserted-by":"crossref","first-page":"327","DOI":"10.1016\/0021-9991(77)90098-5","volume":"23","author":"JP Ryckaert","year":"1977","unstructured":"Ryckaert JP, Ciccotti G, Berendsen HJC (1977) Journal of Computational Physics 23:327","journal-title":"J Comput Phys"},{"key":"232_CR20","doi-asserted-by":"crossref","first-page":"3684","DOI":"10.1063\/1.448118","volume":"81","author":"HJC Berendsen","year":"1984","unstructured":"Berendsen HJC, Postma JPM, Vangunsteren WF, Dinola A, Haak JR (1984) J Chem Phys 81:3684","journal-title":"J Chem Phys"},{"key":"232_CR21","doi-asserted-by":"crossref","first-page":"1701","DOI":"10.1002\/jcc.20291","volume":"26","author":"D Spoel Van Der","year":"2005","unstructured":"Van Der Spoel D, Lindahl E, Hess B, Groenhof G, Mark AE, Berendsen HJ (2005) J Comput Chem 26:1701\u20131718","journal-title":"J Comput Chem"},{"key":"232_CR22","doi-asserted-by":"crossref","first-page":"11225","DOI":"10.1021\/ja9621760","volume":"118","author":"WL Jorgensen","year":"1996","unstructured":"Jorgensen WL, Maxwell DS, Tirado-Rives J (1996) J Am Chem Soc 118:11225\u201311236","journal-title":"J Am Chem Soc"},{"key":"232_CR23","doi-asserted-by":"crossref","first-page":"33","DOI":"10.1016\/0263-7855(96)00018-5","volume":"14","author":"W Humphrey","year":"1996","unstructured":"Humphrey W, Dalke A, Schulten K (1996) J Mol Graph 14:33\u201338, 27\u201338","journal-title":"J Mol Graph"},{"key":"232_CR24","unstructured":"DeLano W, The PyMOL Molecular Graphics System. 2002, DeLano Scientific, San Carlos"},{"key":"232_CR25","doi-asserted-by":"crossref","first-page":"1447","DOI":"10.1016\/j.febslet.2006.01.074","volume":"580","author":"C Hetenyi","year":"2006","unstructured":"Hetenyi C, van der Spoel D (2006) FEBS Lett 580:1447\u20131450","journal-title":"FEBS Lett"},{"key":"232_CR26","doi-asserted-by":"crossref","first-page":"1639","DOI":"10.1002\/(SICI)1096-987X(19981115)19:14<1639::AID-JCC10>3.0.CO;2-B","volume":"19","author":"GM Morris","year":"1998","unstructured":"Morris GM, Goodsell DS, Halliday RS, Huey R, Hart WE, Belew RK, Olson AJ (1998) J Comput Chem 19:1639","journal-title":"J Comput Chem"},{"key":"232_CR27","first-page":"57","volume":"17","author":"MF Sanner","year":"1999","unstructured":"Sanner MF (1999) J Mol Graph Model 17:57\u201361","journal-title":"J Mol Graph Model"},{"key":"232_CR28","doi-asserted-by":"crossref","first-page":"2577","DOI":"10.1002\/bip.360221211","volume":"22","author":"W Kabsch","year":"1983","unstructured":"Kabsch W, Sander C (1983) Biopolymers 22:2577\u20132637","journal-title":"Biopolymers"},{"key":"232_CR29","doi-asserted-by":"crossref","first-page":"1183","DOI":"10.1093\/hmg\/3.7.1183","volume":"3","author":"A Uchiyama","year":"1994","unstructured":"Uchiyama A, Tomatsu S, Kondo N, Suzuki Y, Shimozawa N, Fukuda S, Sukegawa K, Taki N, Inamori H, Orii T (1994) Hum Mol Genet 3:1183\u20131184","journal-title":"Hum Mol Genet"}],"container-title":["Journal of Molecular Modeling"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s00894-007-0232-5.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1007\/s00894-007-0232-5\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s00894-007-0232-5","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,8,22]],"date-time":"2021-08-22T04:36:03Z","timestamp":1629606963000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/s00894-007-0232-5"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2007,8,23]]},"references-count":29,"journal-issue":{"issue":"11","published-print":{"date-parts":[[2007,9,14]]}},"alternative-id":["232"],"URL":"https:\/\/doi.org\/10.1007\/s00894-007-0232-5","relation":{},"ISSN":["1610-2940","0948-5023"],"issn-type":[{"value":"1610-2940","type":"print"},{"value":"0948-5023","type":"electronic"}],"subject":[],"published":{"date-parts":[[2007,8,23]]}}}