{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,8]],"date-time":"2026-07-08T05:33:09Z","timestamp":1783488789441,"version":"3.55.0"},"reference-count":38,"publisher":"Springer Science and Business Media LLC","issue":"2","license":[{"start":{"date-parts":[[2008,7,1]],"date-time":"2008-07-01T00:00:00Z","timestamp":1214870400000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Oral Maxillofac Surg"],"published-print":{"date-parts":[[2008,7]]},"DOI":"10.1007\/s10006-008-0113-9","type":"journal-article","created":{"date-parts":[[2008,7,1]],"date-time":"2008-07-01T06:39:39Z","timestamp":1214894379000},"page":"105-111","source":"Crossref","is-referenced-by-count":23,"title":["Intralesional corticosteroid therapy for mandibular Langerhans cell histiocytosis preserving the intralesional tooth germ"],"prefix":"10.1007","volume":"12","author":[{"given":"Antonios","family":"Moralis","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Martin","family":"Kunkel","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Norbert","family":"Kleinsasser","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Urs","family":"M\u00fcller-Richter","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Torsten Eugen","family":"Reichert","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Oliver","family":"Driemel","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2008,7,2]]},"reference":[{"key":"113_CR1","doi-asserted-by":"crossref","first-page":"91","DOI":"10.1054\/jcms.2001.0271","volume":"30","author":"A Bartnick","year":"2002","unstructured":"Bartnick A, Friedrich RE, R\u00f6ser K, Schmelzle R (2002) Oral Langerhans cell histiocytosis. J Cranio-maxillo-facial Surg 30:91\u201396","journal-title":"J Cranio-maxillo-facial Surg"},{"key":"113_CR2","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/S0074-7696(06)54001-X","volume":"254","author":"GI Bechan","year":"2006","unstructured":"Bechan GI, Egeler RM, Arceci RJ (2006) Biology of Langerhans cells and Langerhans cell histiocytosis. Int Rev Cytol 254:1\u201343","journal-title":"Int Rev Cytol"},{"key":"113_CR3","doi-asserted-by":"crossref","first-page":"55","DOI":"10.1007\/s00106-001-0618-0","volume":"51","author":"G Becker","year":"2003","unstructured":"Becker G, B\u00fccheler M, Paulsen F, Denzlinger C, Belka C, Plinkert PK (2003) Interdisziplin\u00e4re Therapie der Langerhans-Zell-Histiozytose im Kopf und Hals Bereich. HNO 51:55\u201360","journal-title":"HNO"},{"key":"113_CR4","doi-asserted-by":"crossref","first-page":"502","DOI":"10.1111\/j.1651-2227.1996.tb14071.x","volume":"85","author":"C Bernstrand","year":"1996","unstructured":"Bernstrand C, Bj\u00f6rk O, Ahstr\u00f6m L, Henter JI (1996) Intralesional steroids in Langerhans cell histiocytosis of bone. Acta Paediatr 85:502\u2013504","journal-title":"Acta Paediatr"},{"issue":"Suppl 23","key":"113_CR5","first-page":"56","volume":"70","author":"M Brenner","year":"1994","unstructured":"Brenner M (1994) Current status of gene transfer into haemopoietic progenitor cells: application to Langerhans cell histiocytosis. Br J Cancer 70(Suppl 23):56\u201357","journal-title":"Br J Cancer"},{"key":"113_CR6","doi-asserted-by":"crossref","first-page":"312","DOI":"10.1016\/j.otohns.2006.03.019","volume":"135","author":"L Buchmann","year":"2006","unstructured":"Buchmann L, Emami A, Wie JL (2006) Primary head and neck Langerhans cell histiocytosis in children. Otolaryngol Head Neck Surg 135:312\u2013317","journal-title":"Otolaryngol Head Neck Surg"},{"key":"113_CR7","doi-asserted-by":"crossref","first-page":"339","DOI":"10.1097\/01241398-198505000-00016","volume":"5","author":"R Capanna","year":"1985","unstructured":"Capanna R, Springfield DS, Ruggieri P, Biagini R, Picci P, Bacci G, Giunti A, Lorenzi EG, Campanacci M (1985) Direct cortisone injection in eosinophilic granuloma of bone: a preliminary report on 11 patients. J Pediatr Orthop 5:339\u2013342","journal-title":"J Pediatr Orthop"},{"key":"113_CR8","doi-asserted-by":"crossref","first-page":"123","DOI":"10.1016\/S0889-8588(18)30690-7","volume":"1","author":"JR Cassady","year":"1987","unstructured":"Cassady JR (1987) Current role of radiation therapy in the management of histiocytosis-X. Hematol Oncol Clin North Am 1:123\u2013129","journal-title":"Hematol Oncol Clin North Am"},{"key":"113_CR9","first-page":"63","volume-title":"World Health Organization classification of tumours. Pathology and genetics of head and neck tumours","author":"ACL Chan","year":"2005","unstructured":"Chan ACL, Chan JKC, Cheung MMC, Kapadia SB (2005a) Haematolymphoid tumours. In: Barnes L, Eveson JW, Reichart P, Sidransky D (eds) World Health Organization classification of tumours. Pathology and genetics of head and neck tumours. IARC, Lyon, p 63"},{"key":"113_CR10","first-page":"203","volume-title":"World Health Organization classification of tumours. Pathology and genetics of head and neck tumours","author":"ACL Chan","year":"2005","unstructured":"Chan ACL, Chan JKC (2005b) Haematolymphoid tumours. In: Barnes L, Eveson JW, Reichart P, Sidransky D (eds) World Health Organization classification of tumours. Pathology and genetics of head and neck tumours. IARC, Lyon, p 203"},{"key":"113_CR11","doi-asserted-by":"crossref","first-page":"289","DOI":"10.1148\/radiology.136.2.7403498","volume":"136","author":"M Cohen","year":"1980","unstructured":"Cohen M, Zornoza J, Cangir A, Murray JA, Wallace S (1980) Direct injection of methylsodium succinate in the treatment of solitary eosinophilic granuloma of bone. Radiology 136:289\u2013293","journal-title":"Radiology"},{"key":"113_CR12","doi-asserted-by":"crossref","first-page":"786","DOI":"10.1007\/s001060050662","volume":"48","author":"J Constandinidis","year":"2000","unstructured":"Constandinidis J, Waldfahrer F, Iro H (2000) Manifestation der Langerhans-Zellhistiozytose im HNO-Bereich. HNO 48:786\u2013795","journal-title":"HNO"},{"key":"113_CR13","doi-asserted-by":"crossref","first-page":"188","DOI":"10.1002\/path.2167","volume":"212","author":"CET Costa Da","year":"2007","unstructured":"Da Costa CET, Egeler RM, Hoogeboom M, Szuhai K, Forsyth RG, Niesters M, de Krijger RR, Tazi A, Hogendoorn PCW, Annels NE (2007) Differences in telomerase expression by the CD1a + cells in Langerhans cell histiocytosis reflect the diverse clinical presentation of the disease. J Pathol 212:188\u2013197","journal-title":"J Pathol"},{"key":"113_CR14","doi-asserted-by":"crossref","first-page":"736","DOI":"10.1016\/0030-4220(88)90020-5","volume":"65","author":"WK Duncan","year":"1988","unstructured":"Duncan WK, Post AC, McCoy BP (1988) Eosinophilic granuloma. Oral Surg Oral Med Oral Pathol 65:736\u2013741","journal-title":"Oral Surg Oral Med Oral Pathol"},{"key":"113_CR15","doi-asserted-by":"crossref","first-page":"687","DOI":"10.1016\/S1368-8375(03)00080-0","volume":"39","author":"A Eckardt","year":"2003","unstructured":"Eckardt A, Schultze A (2003) Maxillofacial manifestations of Langerhans cell histiocytosis: a clinical and therapeutic analysis of 10 patients. Oral Oncol 39:687\u2013694","journal-title":"Oral Oncol"},{"key":"113_CR16","doi-asserted-by":"crossref","first-page":"811","DOI":"10.1097\/01241398-199211000-00021","volume":"12","author":"RM Egeler","year":"1992","unstructured":"Egeler RM, Thompson RC Jr, Voute PA, Nesbit ME Jr (1992) Intralesional infiltration of corticosteroids in localized Langerhans\u2019 cell histiocytosis. J Pediatr Orthop 12:811\u2013814","journal-title":"J Pediatr Orthop"},{"key":"113_CR17","doi-asserted-by":"crossref","first-page":"1786","DOI":"10.1002\/(SICI)1097-0142(19971101)80:9<1786::AID-CNCR13>3.0.CO;2-1","volume":"80","author":"F Giona","year":"1997","unstructured":"Giona F, Caruso R, Testi AM, Moleti ML, Malagnino F, Martelli M, Ruco L, Giannetti GP, Annibali S, Mandelli F (1997) Langerhans\u2019 cell histiocytosis in adults. A clinical and therapeutic analysis of 11 patients from a single institution. Cancer 80:1786\u20131791","journal-title":"Cancer"},{"key":"113_CR18","first-page":"358","volume-title":"World Health Organization classification of tumours. Pathology and genetics of head and neck tumours","author":"K Henry","year":"2005","unstructured":"Henry K (2005) Langerhans-cell-histiocytosis. In: Barnes L, Eveson JW, Reichart P, Sidransky D (eds) World Health Organization classification of tumours. Pathology and genetics of head and neck tumours. IARC, Lyon, pp 358\u2013359"},{"key":"113_CR19","doi-asserted-by":"crossref","first-page":"492","DOI":"10.1002\/mpo.2950170527","volume":"17","author":"Histiocyte Society Clinical Writing Group","year":"1989","unstructured":"Histiocyte Society Clinical Writing Group (1989) Histiocytosis syndromes in children: Approach to the clinical and laboratory evaluation of children with Langerhans cell histiocytosis. Med Pediatr Oncol 17:492\u2013496","journal-title":"Med Pediatr Oncol"},{"key":"113_CR20","doi-asserted-by":"crossref","first-page":"2278","DOI":"10.1002\/(SICI)1097-0142(19990515)85:10<2278::AID-CNCR25>3.0.CO;2-U","volume":"85","author":"DM Howarth","year":"1999","unstructured":"Howarth DM, Gilchrist GS, Mullan BP, Wiseman GA, Edmonson JH, Schomberg PJ (1999) Langerhans cell histiocytosis: diagnosis, natural history, management, and outcome. Cancer 85:2278\u20132290","journal-title":"Cancer"},{"key":"113_CR21","doi-asserted-by":"crossref","first-page":"306","DOI":"10.1016\/0278-2391(89)90238-3","volume":"47","author":"LR Jones","year":"1989","unstructured":"Jones LR, Toth BB, Cangir A (1989) Treatment for eosinophilic granuloma of the mandible by steroids injection. J Oral Maxillofac Surg 47:306\u2013309","journal-title":"J Oral Maxillofac Surg"},{"issue":"Suppl 23","key":"113_CR22","first-page":"54","volume":"70","author":"KM Kelly","year":"1994","unstructured":"Kelly KM, Pritchard J (1994) Monoclonal antibody therapy in Langerhans cell histiocytosis\u2014feasible and reasonable? Br J Cancer 70(Suppl 23):54\u201355","journal-title":"Br J Cancer"},{"key":"113_CR23","doi-asserted-by":"crossref","first-page":"170","DOI":"10.1016\/j.jcms.2004.01.004","volume":"32","author":"SJ Key","year":"2004","unstructured":"Key SJ, O\u2019Brien CJ, Silvester KC, Crean SJ (2004) Eosinophilic granuloma: Resolution of maxillofacial bony lesions following minimal intervention. Report o three cases and a review of the literature. J Cranio-maxillo-facial Surg 32:170\u2013175","journal-title":"J Cranio-maxillo-facial Surg"},{"key":"113_CR24","doi-asserted-by":"crossref","first-page":"107","DOI":"10.1002\/mpo.2950230207","volume":"23","author":"S Ladisch","year":"1994","unstructured":"Ladisch S, Gadner H, Arico M, Broadbent V, Grois N, Jakobson A, Komp D, Nicholson H (1994) LCH-I: a randomized trial of etoposide versus vinblastine in disseminated Langerhans cell histiocytosis. Med Pediatr Oncol 23:107\u2013110","journal-title":"Med Pediatr Oncol"},{"key":"113_CR25","first-page":"84","volume":"56","author":"L Lichtenstein","year":"1953","unstructured":"Lichtenstein L (1953) Histiocytosis X. Arch Pathol 56:84\u2013102","journal-title":"Arch Pathol"},{"key":"113_CR26","doi-asserted-by":"crossref","first-page":"373","DOI":"10.1111\/j.1365-4362.1991.tb03880.x","volume":"30","author":"Y Matsushima","year":"1991","unstructured":"Matsushima Y, Baba T (1991) Resolution of cutaneous lesions of histiocytosis X by intralesion injections of interferon-beta. Int J Dermatol 30:373\u2013374","journal-title":"Int J Dermatol"},{"key":"113_CR27","doi-asserted-by":"crossref","first-page":"123","DOI":"10.1111\/j.1365-263X.2005.00603.x","volume":"15","author":"T Mitomi","year":"2005","unstructured":"Mitomi T, Tomizawa M, Noda T (2005) Tooth development included in the multifocal jaw lesions of Langerhans cell histiocytosis. Int J Paediatr Dent 15:123\u2013126","journal-title":"Int J Paediatr Dent"},{"key":"113_CR28","first-page":"S52","volume":"23","author":"G Morgan","year":"1994","unstructured":"Morgan G (1994) Myeloablative therapy and bone marrow transplantation for Langerhans cell histiocytosis. Br J Cancer Suppl 23:S52\u2013S53","journal-title":"Br J Cancer Suppl"},{"key":"113_CR29","doi-asserted-by":"crossref","first-page":"227","DOI":"10.1007\/BF00357895","volume":"10","author":"C Nauert","year":"1983","unstructured":"Nauert C, Zornoza J, Ayala A, Harle TS (1983) Eosinophilic granuloma of bone: diagnosis and management. Skelet Radiol 10:227\u2013235","journal-title":"Skelet Radiol"},{"key":"113_CR30","first-page":"365","volume":"18","author":"C Nezelof","year":"1973","unstructured":"Nezelof C, Basset F, Rousseau MF (1973) Histiocytosis X histogenetic arguments for a Langerhans cell origin. Biomedicine 18:365\u2013371","journal-title":"Biomedicine"},{"key":"113_CR31","doi-asserted-by":"crossref","first-page":"131","DOI":"10.1016\/S0889-8588(18)30691-9","volume":"1","author":"ME Osband","year":"1987","unstructured":"Osband ME (1987) Immunotherapy of histiocytosis-X. Hematol Oncol Clin North Am 1:131\u2013145","journal-title":"Hematol Oncol Clin North Am"},{"key":"113_CR32","doi-asserted-by":"crossref","first-page":"97","DOI":"10.1159\/000098380","volume":"43","author":"SH Park","year":"2007","unstructured":"Park SH, Park J, Hwang JH, Hwang SK, Hamm IS, Park YM (2007) Eosinophilic granuloma of the skull: a retrospective analysis. Pediatr Neurosurg 43:97\u2013101","journal-title":"Pediatr Neurosurg"},{"key":"113_CR33","doi-asserted-by":"crossref","first-page":"571","DOI":"10.1016\/j.ijom.2004.10.020","volume":"34","author":"TF Putters","year":"2005","unstructured":"Putters TF, de Visscher JGAM, van Veen A, Spijkervet FKL (2005) Intralesional infiltration of corticosteroids in the treatment of localised Langerhans\u2019 cell histiocytosis of the mandible. Report of known cases and three new cases. Int J Oral Maxillofac Surg 34:571\u2013575","journal-title":"Int J Oral Maxillofac Surg"},{"key":"113_CR34","doi-asserted-by":"crossref","first-page":"33","DOI":"10.1097\/00003086-198205000-00007","volume":"165","author":"O Scaglietti","year":"1982","unstructured":"Scaglietti O, Marchetti PG, Bartolozzi P (1982) Final results obtained in the treatment of bone cysts with methylprednisolone acetate (depo-medrol) and a discussion of results achieved in other bone lesions. Clin Orthop Relat Res 165:33\u201342","journal-title":"Clin Orthop Relat Res"},{"key":"113_CR35","doi-asserted-by":"crossref","first-page":"119","DOI":"10.1016\/S0002-9394(99)00055-0","volume":"128","author":"JH Smith","year":"1999","unstructured":"Smith JH, Fulton L, O\u2019Brien JM (1999) Spontaneous regression of orbital Langerhans cell granulomatosis in a three-year-old girl. Am J Ophthalmol 128:119\u2013121","journal-title":"Am J Ophthalmol"},{"key":"113_CR36","first-page":"S47","volume":"23","author":"PJ Smith","year":"1994","unstructured":"Smith PJ, Soues S (1994) Multilevel therapeutic targeting by topoisomerase inhibitiors. Br J Cancer Suppl 23:S47\u2013S51","journal-title":"Br J Cancer Suppl"},{"key":"113_CR37","doi-asserted-by":"crossref","first-page":"317","DOI":"10.1067\/moe.2000.107535","volume":"90","author":"IM Watzke","year":"2000","unstructured":"Watzke IM, Millesi W, Kermer C, Gisslinger H (2000) Multifocal eosinophilic granuloma of the jaw: long-term follow-up of a novel intraosseous corticoid treatment for recalcitrant lesions. Oral Surg Oral Med Oral Pathol Oral Radiol Endo 90:317\u2013322","journal-title":"Oral Surg Oral Med Oral Pathol Oral Radiol Endo"},{"key":"113_CR38","doi-asserted-by":"crossref","first-page":"E13","DOI":"10.1016\/j.jpedsurg.2005.03.073","volume":"40","author":"GJ Wilson","year":"2005","unstructured":"Wilson GJ, Versluys AB, Bax KN (2005) Solitary Langerhans cell histiocytosis of the sternum in a 6-year-old girl: how should it be treated? J Pediatr Surg 40:E13\u2013E15","journal-title":"J Pediatr Surg"}],"container-title":["Oral and Maxillofacial Surgery"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s10006-008-0113-9.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1007\/s10006-008-0113-9\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s10006-008-0113-9","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,5,19]],"date-time":"2023-05-19T01:30:01Z","timestamp":1684459801000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/s10006-008-0113-9"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2008,7]]},"references-count":38,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2008,7]]}},"alternative-id":["113"],"URL":"https:\/\/doi.org\/10.1007\/s10006-008-0113-9","relation":{},"ISSN":["1865-1550","1865-1569"],"issn-type":[{"value":"1865-1550","type":"print"},{"value":"1865-1569","type":"electronic"}],"subject":[],"published":{"date-parts":[[2008,7]]}}}