{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,5]],"date-time":"2026-11-05T21:45:15Z","timestamp":1793915115711,"version":"4.8.0"},"reference-count":36,"publisher":"Springer Science and Business Media LLC","issue":"3","license":[{"start":{"date-parts":[[2024,4,16]],"date-time":"2024-04-16T00:00:00Z","timestamp":1713225600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"},{"start":{"date-parts":[[2024,4,16]],"date-time":"2024-04-16T00:00:00Z","timestamp":1713225600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"}],"funder":[{"DOI":"10.13039\/501100005187","name":"University of Athens","doi-asserted-by":"crossref","id":[{"id":"10.13039\/501100005187","id-type":"DOI","asserted-by":"crossref"}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Oral Maxillofac Surg"],"abstract":"<jats:title>Abstract<\/jats:title><jats:sec>\n                <jats:title>Purpose<\/jats:title>\n                <jats:p>Our study aims to estimate the prevalence of lingual nerve injury following bilateral sagittal split osteotomy (BSSO).<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Methods<\/jats:title>\n                <jats:p>Two reviewers independently conducted a systematic literature search in the Medline and Scopus databases. The pooled prevalence with 95% confidence intervals (CI) was estimated, and quality assessment, outlier analysis, and influential analysis were performed.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Results<\/jats:title>\n                <jats:p>In total, eleven eligible studies comprising a total of 1,882 participants were included in this meta-analysis. One study was identified as critically influential. The overall prevalence of lingual sensory impairment was estimated to be as high as 0.1% (95% CI 0.0%-0.6%) with moderate heterogeneity observed between studies.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Conclusion<\/jats:title>\n                <jats:p>It is important for healthcare professionals to be aware of this issue, despite the relatively low rate of lingual nerve deficit after BSSO. Additional research will provide a more comprehensive understanding of the underlying factors contributing to lingual nerve injury, leading to improved preventive measures and treatment strategies. Furthermore, insights gained from future studies will enable healthcare professionals to inform patients about the potential complications and manage their expectations before undergoing BSSO.<\/jats:p>\n              <\/jats:sec>","DOI":"10.1007\/s10006-024-01247-w","type":"journal-article","created":{"date-parts":[[2024,4,16]],"date-time":"2024-04-16T04:16:10Z","timestamp":1713240970000},"page":"1055-1062","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":7,"title":["Prevalence of lingual sensory impairment following bilateral sagittal split osteotomy: a systematic review and meta-analysis"],"prefix":"10.1007","volume":"28","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-1332-0479","authenticated-orcid":false,"given":"Evangelos","family":"Kostares","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2361-1050","authenticated-orcid":false,"given":"Michael","family":"Kostares","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Georgia","family":"Kostare","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maria","family":"Kantzanou","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2024,4,16]]},"reference":[{"key":"1247_CR1","doi-asserted-by":"crossref","unstructured":"Krishnamurthy Bonanthaya E, Panneerselvam, Manuel S, Kumar VV Anshul Rai and Springerlink (Online Service (2021). Oral and maxillofacial surgery for the Clinician. Singapore: Springer Singapore, Imprint Springer","DOI":"10.1007\/978-981-15-1346-6"},{"issue":"6","key":"1247_CR2","doi-asserted-by":"publisher","first-page":"716","DOI":"10.1055\/s-0041-1735309","volume":"37","author":"S Bahmanyar","year":"2021","unstructured":"Bahmanyar S, Namin AW, Weiss RO, Vincent AG, Read-Fuller AM, Reddy LV (2021) Orthognathic surgery of the Mandible. Facial Plast Surgery: FPS [online] 37(6):716\u2013721. https:\/\/doi.org\/10.1055\/s-0041-1735309","journal-title":"Facial Plast Surgery: FPS [online]"},{"issue":"03","key":"1247_CR3","doi-asserted-by":"publisher","first-page":"145","DOI":"10.1055\/s-0033-1357111","volume":"27","author":"L \u200cMonson","year":"2013","unstructured":"\u200cMonson L (2013) Bilateral Sagittal Split Osteotomy. Seminars in plastic surgery. [online] 27(03):145\u2013148. https:\/\/doi.org\/10.1055\/s-0033-1357111","journal-title":"[online]"},{"key":"1247_CR4","doi-asserted-by":"publisher","unstructured":"Graff-Radford SB, Evans RW (2003) \u2018Lingual Nerve Injury\u2019, Headache: The Journal of Head and Face Pain, 43(9), pp. 975\u2013983. https:\/\/doi.org\/10.1046\/j.1526-4610.2003.03189.x","DOI":"10.1046\/j.1526-4610.2003.03189.x"},{"key":"1247_CR5","doi-asserted-by":"publisher","unstructured":"Coulthard P, Kushnerev E, Yates JM, Walsh T, Patel N, Bailey E, Renton TF, Cochrane Oral Health Group (2014) \u2018Interventions for iatrogenic inferior alveolar and lingual nerve injury\u2019, Cochrane Database of Systematic Reviews [Preprint]. Edited by. https:\/\/doi.org\/10.1002\/14651858.CD005293.pub2","DOI":"10.1002\/14651858.CD005293.pub2"},{"key":"1247_CR6","unstructured":"Kwon G, Hohman MH (2023) Inferior Alveolar Nerve and Lingual Nerve Injury. [online] PubMed. https:\/\/www.ncbi.nlm.nih.gov\/books\/NBK589668\/ [Accessed 16 Jun. 2023]"},{"key":"1247_CR7","doi-asserted-by":"publisher","unstructured":"D\u2019Agostino A, Favero V, Lanaro L, Zanini M, Nocini PF, Trevisiol L (2019) \u2018Does Piezosurgery Influence the Severity of Neurosensory Disturbance Following Bilateral Sagittal Split Osteotomy?\u2019:, Journal of Craniofacial Surgery, 30(4), pp. 1154\u20131162. https:\/\/doi.org\/10.1097\/SCS.0000000000005251","DOI":"10.1097\/SCS.0000000000005251"},{"key":"1247_CR8","doi-asserted-by":"publisher","unstructured":"Da Senior C, Gemels O, Van Der Cruyssen B, Agbaje F, De Temmerman JO, Shaheen G, Lambrichts E, I. and, Politis C (2020) \u2018Long-term neurosensory disturbances after modified sagittal split osteotomy\u2019, British Journal of Oral and Maxillofacial Surgery, 58(8), pp. 986\u2013991. https:\/\/doi.org\/10.1016\/j.bjoms.2020.05.010","DOI":"10.1016\/j.bjoms.2020.05.010"},{"key":"1247_CR9","doi-asserted-by":"publisher","unstructured":"Thiem DGE, Schneider D, Hammel M, Saka B, Frerich B, Al-Nawas B, K\u00e4mmerer PW (2021) \u2018Complications or rather side effects? Quantification of patient satisfaction and complications after orthognathic surgery\u2014a retrospective, cross-sectional long-term analysis\u2019, Clinical Oral Investigations, 25(5), pp. 3315\u20133327. https:\/\/doi.org\/10.1007\/s00784-020-03664-z","DOI":"10.1007\/s00784-020-03664-z"},{"key":"1247_CR10","doi-asserted-by":"publisher","unstructured":"Page MJ et al (2021) \u2018The PRISMA 2020 statement: an updated guideline for reporting systematic reviews\u2019, BMJ, p. n71. https:\/\/doi.org\/10.1136\/bmj.n71","DOI":"10.1136\/bmj.n71"},{"key":"1247_CR11","unstructured":"www.zotero.org. (n.d.). Zotero | Your personal research assistant. [online] https:\/\/www.zotero.org [Accessed 15 Dec. 2022]"},{"key":"1247_CR12","doi-asserted-by":"publisher","unstructured":"Panula K, Finne K, Oikarinen K (2001) \u2018Incidence of complications and problems related to orthognathic surgery: A review of 655 patients\u2019, Journal of Oral and Maxillofacial Surgery, 59(10), pp. 1128\u20131136. https:\/\/doi.org\/10.1053\/joms.2001.26704","DOI":"10.1053\/joms.2001.26704"},{"key":"1247_CR13","doi-asserted-by":"publisher","unstructured":"Becelli R, Fini G, Renzi G, Giovannetti F, Roefaro E (2004) \u2018Complications of Bicortical Screw Fixation Observed in 482 Mandibular Sagittal Osteotomies\u2019:, Journal of Craniofacial Surgery, 15(1), pp. 64\u201368. https:\/\/doi.org\/10.1097\/00001665-200401000-00019","DOI":"10.1097\/00001665-200401000-00019"},{"key":"1247_CR14","unstructured":"NIH (2009) Study Quality Assessment Tools | National Heart, Lung, and Blood Institute (NHLBI). [online] Nih.gov. https:\/\/www.nhlbi.nih.gov\/health-topics\/study-quality-assessment-tools [Accessed 15 Dec. 2022]"},{"key":"1247_CR15","unstructured":"RStudio D (2022) https:\/\/posit.co\/download\/rstudio-desktop\/"},{"key":"1247_CR16","doi-asserted-by":"publisher","unstructured":"Viechtbauer W (2010) \u2018Conducting Meta-Analyses in R with the metafor Package\u2019, Journal of Statistical Software, 36(3). https:\/\/doi.org\/10.18637\/jss.v036.i03","DOI":"10.18637\/jss.v036.i03"},{"issue":"4","key":"1247_CR17","doi-asserted-by":"publisher","first-page":"138","DOI":"10.1080\/00031305.1978.10479283","volume":"32","author":"JJ Miller","year":"1978","unstructured":"Miller JJ (1978) The Inverse of the Freeman \u2013 Tukey double Arcsine Transformation. Am Stat 32(4):138\u2013138. https:\/\/doi.org\/10.1080\/00031305.1978.10479283","journal-title":"Am Stat"},{"key":"1247_CR18","unstructured":"Cochrane (2019) 9.5.2 Identifying and measuring heterogeneity. [online] Cochrane.org. https:\/\/handbook-5-1.cochrane.org\/chapter_9\/9_5_2_identifying_and_measuring_heterogeneity.htm"},{"key":"1247_CR19","doi-asserted-by":"publisher","unstructured":"Viechtbauer W, Cheung MW-L (2010) \u2018Outlier and influence diagnostics for meta-analysis\u2019, Research Synthesis Methods, 1(2), pp. 112\u2013125. https:\/\/doi.org\/10.1002\/jrsm.11","DOI":"10.1002\/jrsm.11"},{"key":"1247_CR20","unstructured":"Handbook-5-1 cochrane.org. (n.d.). 9.6.5.1 Ensure that there are adequate studies. [online] https:\/\/handbook-5-1.cochrane.org\/chapter_9\/9_6_5_1_ensure_that_there_are_adequate_studies_to_justify.htm [Accessed 27 Dec. 2022]"},{"issue":"7109","key":"1247_CR21","doi-asserted-by":"publisher","first-page":"629","DOI":"10.1136\/bmj.315.7109.629","volume":"315","author":"M Egger","year":"1997","unstructured":"Egger M, Smith GD, Schneider M, Minder C (1997) Bias in meta-analysis detected by a simple, graphical test. BMJ [online] 315(7109):629\u2013634. https:\/\/doi.org\/10.1136\/bmj.315.7109.629","journal-title":"BMJ [online]"},{"key":"1247_CR22","doi-asserted-by":"crossref","unstructured":"Begg CB, Mazumdar M (1994) Operating characteristics of a rank correlation test for publication bias. Biometrics, [online] 50(4), pp.1088\u20131101. https:\/\/pubmed.ncbi.nlm.nih.gov\/7786990\/","DOI":"10.2307\/2533446"},{"key":"1247_CR23","doi-asserted-by":"publisher","unstructured":"Barker TH et al (2021) \u2018Conducting proportional meta-analysis in different types of systematic reviews: a guide for synthesisers of evidence\u2019, BMC medical research methodology, 21(1), p. 189. https:\/\/doi.org\/10.1186\/s12874-021-01381-z","DOI":"10.1186\/s12874-021-01381-z"},{"key":"1247_CR24","doi-asserted-by":"publisher","unstructured":"Bouwman JPB, Husak A, Putnam GD, Becking AG, Tuinzing DB (1995) \u2018Screw fixation following bilateral sagittal ramus osteotomy for mandibular advancement\u2014complications in 700 consecutive cases\u2019, British Journal of Oral and Maxillofacial Surgery, 33(4), pp. 231\u2013234. https:\/\/doi.org\/10.1016\/0266-4356(95)90006-3","DOI":"10.1016\/0266-4356(95)90006-3"},{"issue":"11","key":"1247_CR25","doi-asserted-by":"publisher","first-page":"1231","DOI":"10.1016\/s0278-2391(98)90595-x","volume":"56","author":"M August","year":"1998","unstructured":"August M, Marchena JM, Donady JJ, Kaban LB (1998) Neurosensory deficit and functional impairment after sagittal ramus osteotomy: a long-term follow-up study. J Oral Maxillofac Surg 56(11):1231\u20131235. https:\/\/doi.org\/10.1016\/s0278-2391(98)90595-x","journal-title":"J Oral Maxillofac Surg"},{"issue":"6","key":"1247_CR26","doi-asserted-by":"publisher","first-page":"700","DOI":"10.1016\/s0278-2391(98)90799-6","volume":"56","author":"SC Jacks","year":"1998","unstructured":"Jacks SC, Zuniga JR, Turvey TA, Schalit C (1998) A retrospective analysis of lingual nerve sensory changes after mandibular bilateral sagittal split osteotomy. J Oral Maxillofac Surg 56(6):700\u2013704. https:\/\/doi.org\/10.1016\/s0278-2391(98)90799-6","journal-title":"J Oral Maxillofac Surg"},{"key":"1247_CR27","doi-asserted-by":"publisher","unstructured":"Al-Bishri A, Dahlberg G, Barghash Z, Rosenquist J, Sunzel B (2004) \u2018Incidence of neurosensory disturbance after sagittal split osteotomy alone or combined with genioplasty\u2019, British Journal of Oral and Maxillofacial Surgery, 42(2), pp. 105\u2013111. https:\/\/doi.org\/10.1016\/j.bjoms.2003.12.002","DOI":"10.1016\/j.bjoms.2003.12.002"},{"key":"1247_CR28","doi-asserted-by":"publisher","unstructured":"Kallela I, Laine P, Suuronen R, Lindqvist C, Iizuka T \u2018Assessment of material- and technique-related complications following sagittal split osteotomies stabilized by biodegradable polylactide screws\u2019, Surgery O, Medicine O, Pathology O (2005) Oral Radiology, and Endodontology, 99(1), pp. 4\u201310. https:\/\/doi.org\/10.1016\/j.tripleo.2004.04.017","DOI":"10.1016\/j.tripleo.2004.04.017"},{"key":"1247_CR29","doi-asserted-by":"publisher","unstructured":"Matsushita Y, Nakakuki K, Kosugi M, Kurohara K, Harada K (2016) \u2018Does Intraoral Miniplate Fixation Have Good Postoperative Stability After Sagittal Splitting Ramus Osteotomy? Comparison With Intraoral Bicortical Screw Fixation\u2019, Journal of Oral and Maxillofacial Surgery, 74(1), pp. 181\u2013189. https:\/\/doi.org\/10.1016\/j.joms.2015.06.148","DOI":"10.1016\/j.joms.2015.06.148"},{"key":"1247_CR30","doi-asserted-by":"publisher","unstructured":"Posnick JC, Choi E, Singh N (2016) \u2018Lingual nerve injury in association with sagittal ramus osteotomy and bicortical screw fixation: a review of 523 procedures in 262 subjects\u2019, International Journal of Oral and Maxillofacial Surgery, 45(11), pp. 1445\u20131451. https:\/\/doi.org\/10.1016\/j.ijom.2016.05.017","DOI":"10.1016\/j.ijom.2016.05.017"},{"key":"1247_CR31","doi-asserted-by":"publisher","unstructured":"Sobol DL, Hopper JS, Ettinger RE, Dodson TB, Susarla SM (2022) \u2018Does the use of a piezoelectric saw improve neurosensory recovery following sagittal split osteotomy?\u2019, International Journal of Oral and Maxillofacial Surgery, 51(3), pp. 371\u2013375. https:\/\/doi.org\/10.1016\/j.ijom.2021.07.002","DOI":"10.1016\/j.ijom.2021.07.002"},{"key":"1247_CR32","doi-asserted-by":"publisher","unstructured":"Romsa B, Ruggiero SL (2021) \u2018Diagnosis and Management of Lingual Nerve Injuries\u2019, Oral and Maxillofacial Surgery Clinics of North America, 33(2), pp. 239\u2013248. https:\/\/doi.org\/10.1016\/j.coms.2020.12.006","DOI":"10.1016\/j.coms.2020.12.006"},{"key":"1247_CR33","doi-asserted-by":"publisher","unstructured":"Evangelos Kostares, Kostare G, Kostares M, Kantzanou M (2023) Prevalence of surgical site infections after open reduction and internal fixation for mandibular fractures: a systematic review and meta-analysis. 13(1). https:\/\/doi.org\/10.1038\/s41598-023-37652-6","DOI":"10.1038\/s41598-023-37652-6"},{"key":"1247_CR34","doi-asserted-by":"publisher","unstructured":"Shawky M, Mosleh M, Jan AM, Jadu FM (2016) \u2018Meta-analysis of the Incidence of Lingual Nerve Deficits After Mandibular Bilateral Sagittal Split Osteotomy\u2019, Journal of Craniofacial Surgery, 27(3), pp. 561\u2013564. https:\/\/doi.org\/10.1097\/SCS.0000000000002450","DOI":"10.1097\/SCS.0000000000002450"},{"key":"1247_CR35","doi-asserted-by":"publisher","unstructured":"Lee J, Feng B, Park JS, Foo M, Kruger E (2023) \u2018Incidence of lingual nerve damage following surgical extraction of mandibular third molars with lingual flap retraction: A systematic review and meta-analysis\u2019, PLOS ONE. Edited by T. Chaubal, 18(2), p. e0282185. https:\/\/doi.org\/10.1371\/journal.pone.0282185","DOI":"10.1371\/journal.pone.0282185"},{"key":"1247_CR36","doi-asserted-by":"publisher","unstructured":"Kushnerev E, Yates JM (2015) \u2018Evidence-based outcomes following inferior alveolar and lingual nerve injury and repair: a systematic review\u2019, Journal of Oral Rehabilitation, 42(10), pp. 786\u2013802. https:\/\/doi.org\/10.1111\/joor.12313","DOI":"10.1111\/joor.12313"}],"container-title":["Oral and Maxillofacial Surgery"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s10006-024-01247-w.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s10006-024-01247-w\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s10006-024-01247-w.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,9,6]],"date-time":"2024-09-06T02:02:30Z","timestamp":1725588150000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s10006-024-01247-w"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,4,16]]},"references-count":36,"journal-issue":{"issue":"3","published-online":{"date-parts":[[2024,9]]}},"alternative-id":["1247"],"URL":"https:\/\/doi.org\/10.1007\/s10006-024-01247-w","relation":{},"ISSN":["1865-1569"],"issn-type":[{"value":"1865-1569","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,4,16]]},"assertion":[{"value":"12 July 2023","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"26 March 2024","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"16 April 2024","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"Not applicable.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethics approval and consent to participate"}},{"value":"The authors declare no competing interests.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}},{"value":"The authors declare no financial interest.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Financial interests"}},{"value":"The authors declare no non-financial interests.","order":5,"name":"Ethics","group":{"name":"EthicsHeading","label":"Non-financial interests"}},{"value":"This declaration is not applicable.","order":6,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethical approval"}}]}}