{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,23]],"date-time":"2026-10-23T19:13:23Z","timestamp":1792782803642,"version":"4.5.0"},"reference-count":34,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2026,10,10]],"date-time":"2026-10-10T00:00:00Z","timestamp":1791590400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0"},{"start":{"date-parts":[[2026,10,10]],"date-time":"2026-10-10T00:00:00Z","timestamp":1791590400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0"}],"funder":[{"name":"Yishan Research Project of Jiangsu Cancer Hospital","award":["YSPS202405"],"award-info":[{"award-number":["YSPS202405"]}],"id":[{"id":"https:\/\/ror.org\/03108sf43","id-type":"ROR","asserted-by":"crossref"}]},{"name":"Jiangsu Province Preventive Medical General Program","award":["Ym2023109"],"award-info":[{"award-number":["Ym2023109"]}]},{"name":"\u201c333 Project\u201d of Jiangsu Province"},{"name":"Nanjing postdoctoral project outstanding project"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Oral Maxillofac Surg"],"DOI":"10.1007\/s10006-026-01637-2","type":"journal-article","created":{"date-parts":[[2026,10,10]],"date-time":"2026-10-10T10:16:04Z","timestamp":1791627364000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Global burden of lip and oral cavity cancer attributable to behavioral risk factors, 1990\u20132021: a systematic analysis based on the GBD 2021 database"],"prefix":"10.1007","volume":"30","author":[{"given":"Ting","family":"Qiu","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bo-Lin","family":"Lu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jun-Yi","family":"Liu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chang-Yong","family":"He","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chun","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiang","family":"Ji","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ke-Ru","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jian-Feng","family":"Wu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1307-9312","authenticated-orcid":false,"given":"Li-Rong","family":"Wu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2026,10,10]]},"reference":[{"issue":"3","key":"1637_CR1","doi-asserted-by":"publisher","first-page":"229","DOI":"10.3322\/caac.21834","volume":"74","author":"F Bray","year":"2024","unstructured":"Bray F, Laversanne M, Sung H, Ferlay J, Siegel RL, Soerjomataram I, Jemal A (2024) Global cancer statistics 2022: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries. Cancer J Clin 74(3):229\u2013263. https:\/\/doi.org\/10.3322\/caac.21834","journal-title":"Cancer J Clin"},{"issue":"6","key":"1637_CR2","doi-asserted-by":"publisher","first-page":"394","DOI":"10.3322\/caac.21492","volume":"68","author":"F Bray","year":"2018","unstructured":"Bray F, Ferlay J, Soerjomataram I, Siegel RL, Torre LA, Jemal A (2018) Global cancer statistics 2018: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries. Cancer J Clin 68(6):394\u2013424. https:\/\/doi.org\/10.3322\/caac.21492","journal-title":"Cancer J Clin"},{"issue":"10","key":"1637_CR3","doi-asserted-by":"publisher","first-page":"1139","DOI":"10.1177\/00220345221092751","volume":"101","author":"S Warnakulasuriya","year":"2022","unstructured":"Warnakulasuriya S, Chen THH (2022) Areca Nut and Oral Cancer: Evidence from Studies Conducted in Humans. J Dent Res 101(10):1139\u20131146. https:\/\/doi.org\/10.1177\/00220345221092751","journal-title":"J Dent Res"},{"issue":"10","key":"1637_CR4","doi-asserted-by":"publisher","first-page":"1401","DOI":"10.1001\/jamaoncol.2023.2960","volume":"9","author":"ARD Cunha","year":"2023","unstructured":"GBD 2019 Lip, Oral, Pharyngeal Cancer Collaborators, Cunha ARD, Compton K, Xu R, Mishra R, Drangsholt MT, Antunes JLF, Kerr AR, Acheson AR, Lu D, Wallace LE, Kocarnik JM, Fu W, Dean FE, Pennini A, Henrikson HJ, Alam T, Ababneh E, Abd-Elsalam S, Abdoun M, Hugo FN (2023) The Global, Regional, and National Burden of Adult Lip, Oral, and Pharyngeal Cancer in 204 Countries and Territories: A Systematic Analysis for the Global Burden of Disease Study 2019. JAMA Oncol 9(10):1401\u20131416. https:\/\/doi.org\/10.1001\/jamaoncol.2023.2960","journal-title":"JAMA Oncol"},{"key":"1637_CR5","doi-asserted-by":"publisher","first-page":"1429972","DOI":"10.3389\/fonc.2024.1429972","volume":"14","author":"X Dai","year":"2024","unstructured":"Dai X, Liang Y (2024) Tobacco- and alcohol-attributable burden of early-onset lip, oral cavity, and pharyngeal cancer in 204 countries and territories from 1990 to 2019, with projections to 2040. Front Oncol 14:1429972. https:\/\/doi.org\/10.3389\/fonc.2024.1429972","journal-title":"Front Oncol"},{"issue":"1","key":"1637_CR6","doi-asserted-by":"publisher","first-page":"2500693","DOI":"10.1080\/07853890.2025.2500693","volume":"57","author":"Y Yuan","year":"2025","unstructured":"Yuan Y, Huang JW, Cao JL, Wu JH, Wang LL, Gan H, Xu JH, Ye F (2025) Tobacco and alcohol use are the risk factors responsible for the greatest burden of head and neck cancers: a study from the Global Burden of Disease Study 2019. Ann Med 57(1):2500693. https:\/\/doi.org\/10.1080\/07853890.2025.2500693","journal-title":"Ann Med"},{"issue":"1","key":"1637_CR7","doi-asserted-by":"publisher","first-page":"6071","DOI":"10.1038\/s41467-020-19822-6","volume":"11","author":"M Gormley","year":"2020","unstructured":"Gormley M, Dudding T, Sanderson E, Martin RM, Thomas S, Tyrrell J, Ness AR, Brennan P, Munaf\u00f2 M, Pring M, Boccia S, Olshan AF, Diergaarde B, Hung RJ, Liu G, Davey Smith G, Richmond RC (2020) A multivariable Mendelian randomization analysis investigating smoking and alcohol consumption in oral and oropharyngeal cancer. Nat Commun 11(1):6071. https:\/\/doi.org\/10.1038\/s41467-020-19822-6","journal-title":"Nat Commun"},{"issue":"17","key":"1637_CR8","doi-asserted-by":"publisher","first-page":"18153","DOI":"10.1002\/cam4.6391","volume":"12","author":"J Huang","year":"2023","unstructured":"Huang J, Chan SC, Ko S, Lok V, Zhang L, Lin X, Lucero-Prisno DE 3rd, Xu W, Zheng ZJ, Elcarte E, Withers M, Wong MCS, NCD Global Health Research Group, Association of Pacific Rim Universities (APRU) (2023) Disease burden, risk factors, and trends of lip, oral cavity, pharyngeal cancers: A global analysis. Cancer Med 12(17):18153\u201318164. https:\/\/doi.org\/10.1002\/cam4.6391","journal-title":"Cancer Med"},{"issue":"10","key":"1637_CR9","doi-asserted-by":"publisher","first-page":"2019","DOI":"10.1038\/s41591-022-01990-1","volume":"28","author":"CJL Murray","year":"2022","unstructured":"Murray CJL (2022) The Global Burden of Disease Study at 30 years. Nat Med 28(10):2019\u20132026. https:\/\/doi.org\/10.1038\/s41591-022-01990-1","journal-title":"Nat Med"},{"issue":"10440","key":"1637_CR10","doi-asserted-by":"publisher","first-page":"2100","DOI":"10.1016\/S0140-6736(24)00367-2","volume":"403","author":"GBD 2021 Causes of Death Collaborators","year":"2024","unstructured":"GBD 2021 Causes of Death Collaborators (2024) Global burden of 288 causes of death and life expectancy decomposition in 204 countries and territories and 811 subnational locations, 1990\u20132021: a systematic analysis for the Global Burden of Disease Study 2021. Lancet (London, England) 403(10440):2100\u20132132. https:\/\/doi.org\/10.1016\/S0140-6736(24)00367-2","journal-title":"Lancet (London, England)"},{"issue":"10440","key":"1637_CR11","doi-asserted-by":"publisher","first-page":"2162","DOI":"10.1016\/S0140-6736(24)00933-4","volume":"403","author":"GBD 2021 Risk Factors Collaborators","year":"2024","unstructured":"GBD 2021 Risk Factors Collaborators (2024) Global burden and strength of evidence for 88 risk factors in 204 countries and 811 subnational locations, 1990\u20132021: a systematic analysis for the Global Burden of Disease Study 2021. Lancet (London England) 403(10440):2162\u20132203. https:\/\/doi.org\/10.1016\/S0140-6736(24)00933-4","journal-title":"Lancet (London England)"},{"issue":"10482","key":"1637_CR12","doi-asserted-by":"publisher","first-page":"897","DOI":"10.1016\/S0140-6736(24)02811-3","volume":"405","author":"GBD 2021 Oral Disorders Collaborators","year":"2025","unstructured":"GBD 2021 Oral Disorders Collaborators (2025) Trends in the global, regional, and national burden of oral conditions from 1990 to 2021: a systematic analysis for the Global Burden of Disease Study 2021. Lancet (London England) 405(10482):897\u2013910. https:\/\/doi.org\/10.1016\/S0140-6736(24)02811-3","journal-title":"Lancet (London England)"},{"issue":"10440","key":"1637_CR13","doi-asserted-by":"publisher","first-page":"2259","DOI":"10.1016\/S0140-6736(24)00769-4","volume":"403","author":"CJL Murray","year":"2024","unstructured":"Murray CJL, GBD 2021 Collaborators (2024) Findings from the Global Burden of Disease Study 2021. Lancet (London England) 403(10440):2259\u20132262. https:\/\/doi.org\/10.1016\/S0140-6736(24)00769-4","journal-title":"Lancet (London England)"},{"issue":"1","key":"1637_CR14","doi-asserted-by":"publisher","first-page":"4","DOI":"10.1186\/1478-7954-1-4","volume":"1","author":"JJ Barendregt","year":"2003","unstructured":"Barendregt JJ, Van Oortmarssen GJ, Vos T, Murray CJ (2003) A generic model for the assessment of disease epidemiology: the computational basis of DisMod II. Popul Health Metrics 1(1):4. https:\/\/doi.org\/10.1186\/1478-7954-1-4","journal-title":"Popul Health Metrics"},{"issue":"3","key":"1637_CR15","doi-asserted-by":"publisher","first-page":"e142","DOI":"10.1016\/S2665-9913(23)00321-1","volume":"6","author":"GBD 2021 Neck Pain Collaborators","year":"2024","unstructured":"GBD 2021 Neck Pain Collaborators (2024) Global, regional, and national burden of neck pain, 1990\u20132020, and projections to 2050: a systematic analysis of the Global Burden of Disease Study 2021. Lancet Rheumatol 6(3):e142\u2013e155. https:\/\/doi.org\/10.1016\/S2665-9913(23)00321-1","journal-title":"Lancet Rheumatol"},{"issue":"9063","key":"1637_CR16","doi-asserted-by":"publisher","first-page":"1436","DOI":"10.1016\/S0140-6736(96)07495-8","volume":"349","author":"CJ Murray","year":"1997","unstructured":"Murray CJ, Lopez AD (1997) Global mortality, disability, and the contribution of risk factors: Global Burden of Disease Study. Lancet (London England) 349(9063):1436\u20131442. https:\/\/doi.org\/10.1016\/S0140-6736(96)07495-8","journal-title":"Lancet (London England)"},{"issue":"10440","key":"1637_CR17","doi-asserted-by":"publisher","first-page":"2133","DOI":"10.1016\/S0140-6736(24)00757-8","volume":"403","author":"GBD 2021 Diseases and Injuries Collaborators","year":"2024","unstructured":"GBD 2021 Diseases and Injuries Collaborators (2024) Global incidence, prevalence, years lived with disability (YLDs), disability-adjusted life-years (DALYs), and healthy life expectancy (HALE) for 371 diseases and injuries in 204 countries and territories and 811 subnational locations, 1990\u20132021: a systematic analysis for the Global Burden of Disease Study 2021. Lancet (London England) 403(10440):2133\u20132161. https:\/\/doi.org\/10.1016\/S0140-6736(24)00757-8","journal-title":"Lancet (London England)"},{"key":"1637_CR18","doi-asserted-by":"publisher","first-page":"812","DOI":"10.1016\/j.jad.2025.03.094","volume":"379","author":"Y Shan","year":"2025","unstructured":"Shan Y, Liu L, Wang F, Yu L, Liu D, Zheng C, He Q, Li C, Li S, Yu Z (2025) Association between inequalities in mental health resources and burdens of mental health disorders in 146 countries and territories: An observational study. J Affect Disord 379:812\u2013821. https:\/\/doi.org\/10.1016\/j.jad.2025.03.094","journal-title":"J Affect Disord"},{"issue":"10\u201311","key":"1637_CR19","doi-asserted-by":"publisher","first-page":"3363","DOI":"10.1177\/0962280218801121","volume":"28","author":"PS Rosenberg","year":"2019","unstructured":"Rosenberg PS (2019) A new age-period-cohort model for cancer surveillance research. Stat Methods Med Res 28(10\u201311):3363\u20133391. https:\/\/doi.org\/10.1177\/0962280218801121","journal-title":"Stat Methods Med Res"},{"key":"1637_CR20","doi-asserted-by":"publisher","first-page":"1008598","DOI":"10.3389\/fpubh.2022.1008598","volume":"10","author":"B Zhu","year":"2022","unstructured":"Zhu B, Wang Y, Zhou W, Jin S, Shen Z, Zhang H, Zhang X, Ding X, Li Y (2022) Trend dynamics of gout prevalence among the Chinese population, 1990\u20132019: A joinpoint and age-period-cohort analysis. Front Public Health 10:1008598. https:\/\/doi.org\/10.3389\/fpubh.2022.1008598","journal-title":"Front Public Health"},{"key":"1637_CR21","doi-asserted-by":"publisher","first-page":"1302436","DOI":"10.3389\/fendo.2024.1302436","volume":"15","author":"Y Wei","year":"2024","unstructured":"Wei Y, Qin Z, Liao X, Zhou X, Huang H, Lan C, Qin W, Zhu G, Su H, Peng T (2024) Pancreatic cancer mortality trends attributable to high fasting blood sugar over the period 1990\u20132019 and projections up to 2040. Front Endocrinol 15:1302436. https:\/\/doi.org\/10.3389\/fendo.2024.1302436","journal-title":"Front Endocrinol"},{"key":"1637_CR22","doi-asserted-by":"publisher","first-page":"103051","DOI":"10.1016\/j.eclinm.2024.103051","volume":"80","author":"L Yuan","year":"2025","unstructured":"Yuan L, Tao J, Wang J, She W, Zou Y, Li R, Ma Y, Sun C, Bi S, Wei S, Chen H, Guo X, Tian H, Xu J, Dong Y, Ma Y, Sun H, Lv W, Shang Z, Jiang Y, Zhang M (2025) Global, regional, national burden of asthma from 1990 to 2021, with projections of incidence to 2050: a systematic analysis of the global burden of disease study 2021. EClinicalMedicine 80:103051. https:\/\/doi.org\/10.1016\/j.eclinm.2024.103051","journal-title":"EClinicalMedicine"},{"key":"1637_CR23","doi-asserted-by":"publisher","first-page":"1604353","DOI":"10.3389\/ijph.2022.1604353","volume":"67","author":"N Maldonado","year":"2022","unstructured":"Maldonado N, Llorente B, Reynales-Shigematsu LM, Saenz-de-Miera B, Jha P, Shannon G (2022) Tobacco Taxes as the Unsung Hero: Impact of a Tax Increase on Advancing Sustainable Development in Colombia. Int J Public Health 67:1604353. https:\/\/doi.org\/10.3389\/ijph.2022.1604353","journal-title":"Int J Public Health"},{"key":"1637_CR24","volume-title":"NIH Pub No. 17-CA-8035A","author":"U.S. National Cancer Institute. A Socioecological Approach to Addressing Tobacco-Related Health Disparities. National Cancer Institute Tobacco Control Monograph 22","year":"2017","unstructured":"U.S. National Cancer Institute. A Socioecological Approach to Addressing Tobacco-Related Health Disparities. National Cancer Institute Tobacco Control Monograph 22 (2017) NIH Pub No. 17-CA-8035A. US Dept of Health and Human Services, National Institutes of Health, National Cancer Institute, Bethesda, MD"},{"issue":"5","key":"1637_CR25","doi-asserted-by":"publisher","first-page":"e20331","DOI":"10.1371\/journal.pone.0020331","volume":"6","author":"AR Hosseinpoor","year":"2011","unstructured":"Hosseinpoor AR, Parker LA, Tursan d\u2019Espaignet E, Chatterji S (2011) Social determinants of smoking in low- and middle-income countries: results from the World Health Survey. PLoS ONE 6(5):e20331. https:\/\/doi.org\/10.1371\/journal.pone.0020331","journal-title":"PLoS ONE"},{"issue":"12","key":"1637_CR26","doi-asserted-by":"publisher","first-page":"2748","DOI":"10.1002\/ijc.30697","volume":"140","author":"D Holzinger","year":"2017","unstructured":"Holzinger D, Wichmann G, Baboci L, Michel A, H\u00f6fler D, Wiesenfarth M, Schroeder L, Boscolo-Rizzo P, Herold-Mende C, Dyckhoff G, Boehm A, Del Mistro A, Bosch FX, Dietz A, Pawlita M, Waterboer T (2017) Sensitivity and specificity of antibodies against HPV16 E6 and other early proteins for the detection of HPV16-driven oropharyngeal squamous cell carcinoma. Int J Cancer 140(12):2748\u20132757. https:\/\/doi.org\/10.1002\/ijc.30697","journal-title":"Int J Cancer"},{"issue":"4","key":"1637_CR27","doi-asserted-by":"publisher","first-page":"613","DOI":"10.3126\/nje.v6i4.17255","volume":"6","author":"N Gupta","year":"2016","unstructured":"Gupta N, Gupta R, Acharya AK, Patthi B, Goud V, Reddy S, Garg A, Singla A (2016) Changing Trends in oral cancer - a global scenario. Nepal J Epidemiol 6(4):613\u2013619. https:\/\/doi.org\/10.3126\/nje.v6i4.17255","journal-title":"Nepal J Epidemiol"},{"issue":"9972","key":"1637_CR28","doi-asserted-by":"publisher","first-page":"1029","DOI":"10.1016\/S0140-6736(15)60312-9","volume":"385","author":"AB Gilmore","year":"2015","unstructured":"Gilmore AB, Fooks G, Drope J, Bialous SA, Jackson RR (2015) Exposing and addressing tobacco industry conduct in low-income and middle-income countries. Lancet 385(9972):1029\u20131043. https:\/\/doi.org\/10.1016\/S0140-6736(15)60312-9","journal-title":"Lancet"},{"issue":"1","key":"1637_CR29","doi-asserted-by":"publisher","first-page":"5","DOI":"10.1186\/s12199-020-00924-y","volume":"26","author":"A Jafari","year":"2021","unstructured":"Jafari A, Rajabi A, Gholian-Aval M, Peyman N, Mahdizadeh M, Tehrani H (2021) National, regional, and global prevalence of cigarette smoking among women\/females in the general population: a systematic review and meta-analysis. Environ Health Prev Med 26(1):5. https:\/\/doi.org\/10.1186\/s12199-020-00924-y","journal-title":"Environ Health Prev Med"},{"issue":"3","key":"1637_CR30","doi-asserted-by":"publisher","first-page":"143","DOI":"10.1038\/s41568-021-00423-4","volume":"22","author":"SS Hecht","year":"2022","unstructured":"Hecht SS, Hatsukami DK (2022) Smokeless tobacco and cigarette smoking: chemical mechanisms and cancer prevention. Nat Rev Cancer 22(3):143\u2013155. https:\/\/doi.org\/10.1038\/s41568-021-00423-4","journal-title":"Nat Rev Cancer"},{"issue":"9","key":"1637_CR31","doi-asserted-by":"publisher","first-page":"3173","DOI":"10.3390\/nu13093173","volume":"13","author":"H Rumgay","year":"2021","unstructured":"Rumgay H, Murphy N, Ferrari P, Soerjomataram I (2021) Alcohol and Cancer: Epidemiology and Biological Mechanisms. Nutrients 13(9):3173. https:\/\/doi.org\/10.3390\/nu13093173","journal-title":"Nutrients"},{"issue":"7","key":"1637_CR32","doi-asserted-by":"publisher","first-page":"e1003178","DOI":"10.1371\/journal.pmed.1003178","volume":"17","author":"SC Larsson","year":"2020","unstructured":"Larsson SC, Carter P, Kar S, Vithayathil M, Mason AM, Micha\u00eblsson K, Burgess S (2020) Smoking, alcohol consumption, and cancer: A mendelian randomisation study in UK Biobank and international genetic consortia participants. PLoS Med 17(7):e1003178. https:\/\/doi.org\/10.1371\/journal.pmed.1003178","journal-title":"PLoS Med"},{"issue":"11","key":"1637_CR33","doi-asserted-by":"publisher","first-page":"e113385","DOI":"10.1371\/journal.pone.0113385","volume":"9","author":"B Gupta","year":"2014","unstructured":"Gupta B, Johnson NW (2014) Systematic review and meta-analysis of association of smokeless tobacco and of betel quid without tobacco with incidence of oral cancer in South Asia and the Pacific. PLoS ONE 9(11):e113385. https:\/\/doi.org\/10.1371\/journal.pone.0113385","journal-title":"PLoS ONE"},{"key":"1637_CR34","doi-asserted-by":"publisher","first-page":"1397179","DOI":"10.3389\/froh.2024.1397179","volume":"5","author":"A Jasim","year":"2024","unstructured":"Jasim A, Li X, Octavia A, Gunardi I, Crocombe L, Sari EF (2024) The association between betel quid use and oral potentially malignant and malignant disorders in Southeast Asian and Pacific regions: a systematic review and meta-analysis with GRADE evidence profile. Front Oral Health 5:1397179. https:\/\/doi.org\/10.3389\/froh.2024.1397179","journal-title":"Front Oral Health"}],"container-title":["Oral and Maxillofacial Surgery"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s10006-026-01637-2.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s10006-026-01637-2","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s10006-026-01637-2.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,10,10]],"date-time":"2026-10-10T10:16:05Z","timestamp":1791627365000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s10006-026-01637-2"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,10,10]]},"references-count":34,"journal-issue":{"issue":"1","published-online":{"date-parts":[[2026,12]]}},"alternative-id":["1637"],"URL":"https:\/\/doi.org\/10.1007\/s10006-026-01637-2","relation":{},"ISSN":["1865-1569"],"issn-type":[{"value":"1865-1569","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,10,10]]},"assertion":[{"value":"12 February 2026","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"12 September 2026","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"10 October 2026","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"The authors declare no competing interests.","order":1,"name":"Ethics","label":"Competing interests","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"Not applicable.","order":2,"name":"Ethics","label":"Clinical trial number","group":{"name":"EthicsHeading","label":"Declarations"}}],"article-number":"159"}}