{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,13]],"date-time":"2026-01-13T06:11:39Z","timestamp":1768284699582,"version":"3.49.0"},"reference-count":12,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2017,12,20]],"date-time":"2017-12-20T00:00:00Z","timestamp":1513728000000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Brain Tumor Pathol"],"published-print":{"date-parts":[[2018,1]]},"DOI":"10.1007\/s10014-017-0305-9","type":"journal-article","created":{"date-parts":[[2017,12,20]],"date-time":"2017-12-20T07:59:55Z","timestamp":1513756795000},"page":"29-35","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":7,"title":["A case report of adult cerebellar high-grade glioma with H3.1 K27M mutation: a rare example of an H3 K27M mutant cerebellar tumor"],"prefix":"10.1007","volume":"35","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-5847-635X","authenticated-orcid":false,"given":"Nobuaki","family":"Funata","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sumihito","family":"Nobusawa","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Satoshi","family":"Nakata","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tatsuya","family":"Yamazaki","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kazuhiko","family":"Takabagake","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tsukasa","family":"Koike","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tatsuya","family":"Maegawa","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ryoji","family":"Yamada","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nobusada","family":"Shinoura","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yutaka","family":"Mine","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2017,12,20]]},"reference":[{"key":"305_CR1","first-page":"57","volume-title":"WHO Classification of Tumours of the Central Nervous System","author":"CE Hawkins","year":"2016","unstructured":"Hawkins CE, Ellison DW, Sturm D (2016) Diffuse midline glioma, H3 K27M-mutant. In: Louis DN, Ohgaki H, Wiestler OD, Cavenee WK, Ellison DW (eds) WHO Classification of Tumours of the Central Nervous System. IARC Press, Lyon, pp\u00a057\u201359"},{"key":"305_CR2","doi-asserted-by":"crossref","first-page":"815","DOI":"10.1007\/s00401-015-1478-0","volume":"130","author":"D Castel","year":"2015","unstructured":"Castel D, Phillipe C, Calmon R et al (2015) Histone H3F3A and HIST1H3B K27M mutations define two subgroups of diffuse intrinsic pontine gliomas with different prognosis and phenotypes. Acta Neuropathol 130:815\u2013827","journal-title":"Acta Neuropathol"},{"key":"305_CR3","doi-asserted-by":"crossref","first-page":"251","DOI":"10.1038\/ng.1102","volume":"44","author":"G Wu","year":"2012","unstructured":"Wu G, Broniscer A, McEachron TA et al (2012) Somatic Histone H3 alterations in paediatric diffuse intrinsic pontine gliomas and non-brainstem glioblastomas. Nat Genet 44:251\u2013253","journal-title":"Nat Genet"},{"key":"305_CR4","doi-asserted-by":"crossref","first-page":"520","DOI":"10.1016\/j.ccell.2017.08.017","volume":"32","author":"A Mackay","year":"2017","unstructured":"Mackay A, Burford A, Carvalho D et al (2017) Integrated molecular meta-analysis of 1000 pediatric high-grade and diffuse intrinsic pontine glioma. Cancer Cell 32:520\u2013537","journal-title":"Cancer Cell"},{"key":"305_CR5","doi-asserted-by":"crossref","first-page":"113","DOI":"10.1007\/s10014-017-0288-6","volume":"34","author":"S Nakata","year":"2017","unstructured":"Nakata S, Nobusawa S, Yamazaki T et al (2017) Histone H3 K27M mutations in adult cerebellar high-grade gliomas. Brain Tumor Pathol 34:113\u2013119","journal-title":"Brain Tumor Pathol"},{"key":"305_CR6","doi-asserted-by":"publisher","DOI":"10.1007\/s00401-017-1771-1","author":"M Nomura","year":"2017","unstructured":"Nomura M, Mukasa A, Nagae G et al (2017) Distinct molecular profile of diffuse cerebellar gliomas. Acta Neuropathol. \n                        https:\/\/doi.org\/10.1007\/s00401-017-1771-1","journal-title":"Acta Neuropathol"},{"key":"305_CR7","doi-asserted-by":"crossref","first-page":"558","DOI":"10.1111\/bpa.12042","volume":"23","author":"S Venneti","year":"2013","unstructured":"Venneti S, Garimella MT, Sullivan LM et al (2013) Evaluation of Histone 3 lysine 27 trimethylation (H3K27me3) and enhancer of zest 2 (EZH2) in pediatric glial and glioneuronal tumors shows decreased H3K27me3 in H3F3A K27M mutant glioblastomas. Brain Pathol 23:558\u2013564","journal-title":"Brain Pathol"},{"key":"305_CR8","doi-asserted-by":"crossref","first-page":"217","DOI":"10.1111\/j.1750-3639.1996.tb00848.x","volume":"6","author":"K Watanabe","year":"1996","unstructured":"Watanabe K, Tachibana O, Sato K et al (1996) Overexpression of the EGF receptor and p53 mutations are mutually exclusive in the evolution of primary and secondary glioblastomas. Brain Pathol 6:217\u2013224","journal-title":"Brain Pathol"},{"key":"305_CR9","doi-asserted-by":"crossref","first-page":"569","DOI":"10.1111\/bpa.12336","volume":"26","author":"DA Solomon","year":"2016","unstructured":"Solomon DA, Wood MD, Tihan T et al (2016) Diffuse midline gliomas with Histone H3-K27M mutation: a series of 47 cases assessing the spectrum of morphologic variation and associated genetic alterations. Brain Pathol 26:569\u2013580","journal-title":"Brain Pathol"},{"key":"305_CR10","doi-asserted-by":"crossref","first-page":"457","DOI":"10.1111\/j.1440-1789.2007.00795.x","volume":"27","author":"S Kinjo","year":"2007","unstructured":"Kinjo S, Yokoo H, Hirato J et al (2007) Anaplastic astrocytoma with eosinophilic granular cells. Neuropathol 27:457\u2013462","journal-title":"Neuropathol"},{"key":"305_CR11","doi-asserted-by":"publisher","DOI":"10.3174\/ajnr.A5076","author":"MS Aboian","year":"2017","unstructured":"Aboian MS, Solomon DA, Mabray MC et al (2017) Imaging characteristics of pediatric diffuse midline gliomas with histon H3 K27M mutations. AJNR. \n                        https:\/\/doi.org\/10.3174\/ajnr.A5076","journal-title":"AJNR"},{"key":"305_CR12","doi-asserted-by":"crossref","first-page":"451","DOI":"10.1038\/ng.2936","volume":"46","author":"P Buczkowicz","year":"2014","unstructured":"Buczkowicz P, Hoeman C, Rakopoulos et al (2014) Genomic analysis of diffuse intrinsic pontine gliomas identifies three molecular subgroups and recurrent activating ACVR1 mutations. Nat Genet 46:451\u2013456","journal-title":"Nat Genet"}],"container-title":["Brain Tumor Pathology"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/article\/10.1007\/s10014-017-0305-9\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s10014-017-0305-9.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s10014-017-0305-9.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2018,1,24]],"date-time":"2018-01-24T12:23:29Z","timestamp":1516796609000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/s10014-017-0305-9"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,12,20]]},"references-count":12,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2018,1]]}},"alternative-id":["305"],"URL":"https:\/\/doi.org\/10.1007\/s10014-017-0305-9","relation":{},"ISSN":["1433-7398","1861-387X"],"issn-type":[{"value":"1433-7398","type":"print"},{"value":"1861-387X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2017,12,20]]}}}