{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,20]],"date-time":"2026-07-20T11:49:55Z","timestamp":1784548195404,"version":"3.55.0"},"reference-count":18,"publisher":"Springer Science and Business Media LLC","issue":"3-4","license":[{"start":{"date-parts":[[2024,9,8]],"date-time":"2024-09-08T00:00:00Z","timestamp":1725753600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"},{"start":{"date-parts":[[2024,9,8]],"date-time":"2024-09-08T00:00:00Z","timestamp":1725753600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"}],"funder":[{"name":"JSPS KAKENHI","award":["Grant Number JP 20K09320"],"award-info":[{"award-number":["Grant Number JP 20K09320"]}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Brain Tumor Pathol"],"published-print":{"date-parts":[[2024,10]]},"DOI":"10.1007\/s10014-024-00489-6","type":"journal-article","created":{"date-parts":[[2024,9,8]],"date-time":"2024-09-08T12:01:50Z","timestamp":1725796910000},"page":"139-144","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Novel case of ependymoma-like tumor with mesenchymal differentiation harboring ZFTA::RELA fusion in an adult"],"prefix":"10.1007","volume":"41","author":[{"given":"Hirohisa","family":"Yajima","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shunsaku","family":"Takayanagi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hirokazu","family":"Takami","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shota","family":"Tanaka","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Masashi","family":"Nomura","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kaishi","family":"Satomi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Masako","family":"Ikemura","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sumihito","family":"Nobusawa","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ryuta","family":"Saito","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Akihide","family":"Kondo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nobuhito","family":"Saito","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2024,9,8]]},"reference":[{"issue":"7489","key":"489_CR1","doi-asserted-by":"publisher","first-page":"451","DOI":"10.1038\/nature13109","volume":"506","author":"M Parker","year":"2014","unstructured":"Parker M, Mohankumar KM, Punchihewa C et al (2014) C11orf95-RELA fusions drive oncogenic NF-\u03baB signalling in ependymoma. Nature 506(7489):451\u2013455","journal-title":"Nature"},{"issue":"5","key":"489_CR2","doi-asserted-by":"publisher","first-page":"728","DOI":"10.1016\/j.ccell.2015.04.002","volume":"27","author":"KW Pajtler","year":"2015","unstructured":"Pajtler KW, Witt H, Sill M et al (2015) Molecular classification of ependymal tumors across All CNS 2 compartments, histopathological grades, and age groups. Cancer Cell 27(5):728\u2013743","journal-title":"Cancer Cell"},{"issue":"3","key":"489_CR3","doi-asserted-by":"publisher","DOI":"10.1111\/bpa.12943","volume":"31","author":"R Tomomasa","year":"2021","unstructured":"Tomomasa R, Arai Y, Kawabata-Iwakawa R et al (2021) Ependymoma-like tumor with mesenchymal differentiation harboring C11orf95-NCOA1\/2 or -RELA fusion: a hitherto unclassified tumor related to ependymoma. Brain Pathol 31(3):e12943","journal-title":"Brain Pathol"},{"key":"489_CR4","doi-asserted-by":"publisher","DOI":"10.1111\/neup.12952","author":"P Dorwal","year":"2023","unstructured":"Dorwal P, White C, Goh AF et al (2023) Ependymoma-like tumor with mesenchymal differentiation (ELTMD) with ZFTA:NCOA1 fusion: a diagnostic challenge. Neuropathology. https:\/\/doi.org\/10.1111\/neup.12952","journal-title":"Neuropathology"},{"issue":"5","key":"489_CR5","doi-asserted-by":"publisher","first-page":"689","DOI":"10.1111\/j.1750-3639.2012.00574.x","volume":"22","author":"S Nobusawa","year":"2012","unstructured":"Nobusawa S, Yokoo H, Hirato J et al (2012) Analysis of chromosome 19q13.42 amplification in embryonal brain tumors with ependymoblastic multilayered rosettes. Brain Pathol 22(5):689\u2013697","journal-title":"Brain Pathol"},{"issue":"2","key":"489_CR6","doi-asserted-by":"publisher","first-page":"167","DOI":"10.1093\/jnen\/nlv017","volume":"75","author":"S Nobusawa","year":"2016","unstructured":"Nobusawa S, Hirato J, Sugai T et al (2016) Atypical teratoid\/rhabdoid Tumor (AT\/RT) arising from ependymoma: a type of AT\/RT secondarily developing from other primary central nervous system tumors. J Neuropathol Exp Neurol 75(2):167\u2013174","journal-title":"J Neuropathol Exp Neurol"},{"issue":"3","key":"489_CR7","doi-asserted-by":"publisher","first-page":"224","DOI":"10.1002\/gcc.20731","volume":"49","author":"J Sumegi","year":"2010","unstructured":"Sumegi J, Streblow R, Frayer RW et al (2010) Recurrent t(2;2) and t(2;8) translocations in rhabdomyosarcoma without the canonical PAX-FOXO1 fuse PAX3 to members of the nuclear receptor transcriptional coactivator family. Genes Chromosom Cancer 49(3):224\u2013236","journal-title":"Genes Chromosom Cancer"},{"issue":"7697","key":"489_CR8","doi-asserted-by":"publisher","first-page":"469","DOI":"10.1038\/nature26000","volume":"555","author":"D Capper","year":"2018","unstructured":"Capper D, Jones DTW, Sill M et al (2018) DNA methylation-based classification of central nervous system tumours. Nature 555(7697):469\u2013474","journal-title":"Nature"},{"issue":"2","key":"489_CR9","doi-asserted-by":"publisher","first-page":"181","DOI":"10.1007\/s00401-018-1879-y","volume":"136","author":"D Capper","year":"2018","unstructured":"Capper D, Stichel D, Sahm F et al (2018) Practical implementation of DNA methylation and copy-number-based CNS tumor diagnostics: the Heidelberg experience. Acta Neuropathol 136(2):181\u2013210","journal-title":"Acta Neuropathol"},{"issue":"4","key":"489_CR10","doi-asserted-by":"publisher","first-page":"609","DOI":"10.1007\/s00401-014-1264-4","volume":"127","author":"T Pietsch","year":"2014","unstructured":"Pietsch T, Wohlers I, Goschzik T et al (2014) Supratentorial ependymomas of childhood carry C11orf95-RELA fusions leading to pathological activation of the NF-\u03baB signaling pathway. Acta Neuropathol 127(4):609\u2013611","journal-title":"Acta Neuropathol"},{"issue":"5","key":"489_CR11","doi-asserted-by":"publisher","first-page":"863","DOI":"10.1111\/bpa.12866","volume":"30","author":"DW Ellison","year":"2020","unstructured":"Ellison DW, Aldape KD, Capper D et al (2020) cIMPACT-NOW update 7: advancing the molecular classification of ependymal tumors. Brain Pathol. 30(5):863\u2013866","journal-title":"Brain Pathol."},{"issue":"5","key":"489_CR12","doi-asserted-by":"publisher","first-page":"412","DOI":"10.1111\/neup.12770","volume":"41","author":"S Mahajan","year":"2021","unstructured":"Mahajan S, Nambirajan A, Sharma A et al (2021) Ependymosarcoma harboring C11orf95:RELA fusion transcript: report of two cases and review of the literature. Neuropathology 41(5):412\u2013421","journal-title":"Neuropathology"},{"issue":"21","key":"489_CR13","doi-asserted-by":"publisher","first-page":"5419","DOI":"10.3390\/cancers14215419","volume":"14","author":"KS Wu","year":"2022","unstructured":"Wu KS, Sung SY, Huang MH et al (2022) Clinical and molecular features in medulloblastomas subtypes in children in a cohort in Taiwan. Cancers. 14(21):5419","journal-title":"Cancers."},{"issue":"4","key":"489_CR14","doi-asserted-by":"publisher","first-page":"1933","DOI":"10.21873\/anticanres.15671","volume":"42","author":"J Polivka","year":"2022","unstructured":"Polivka J, Svajdler M, Priban V et al (2022) Oncogenic fusions in gliomas: an institutional experience. Anticancer Res 42(4):1933\u20131939","journal-title":"Anticancer Res"},{"issue":"2","key":"489_CR15","doi-asserted-by":"publisher","first-page":"105","DOI":"10.1007\/s10014-014-0205-1","volume":"32","author":"D Cachia","year":"2015","unstructured":"Cachia D, Wani K, Penas-Prado M et al (2015) C11orf95-RELA fusion present in a primary supratentorial ependymoma and recurrent sarcoma. Brain Tumor Pathol 32(2):105\u2013111","journal-title":"Brain Tumor Pathol"},{"issue":"8","key":"489_CR16","doi-asserted-by":"publisher","first-page":"1231","DOI":"10.1093\/neuonc\/noab106","volume":"23","author":"DN Louis","year":"2021","unstructured":"Louis DN, Perry A, Wesseling P et al (2021) The 2021 WHO classification of tumors of the central nervous system: a summary. Neuro Oncol 23(8):1231\u20131251","journal-title":"Neuro Oncol"},{"issue":"18","key":"489_CR17","first-page":"5358","volume":"48","author":"FP Li","year":"1988","unstructured":"Li FP, Fraumeni JF Jr, Mulvihill JJ et al (1988) A cancer family syndrome in twenty-four kindreds. Can Res 48(18):5358\u20135362","journal-title":"Can Res"},{"issue":"21","key":"489_CR18","doi-asserted-by":"publisher","first-page":"2345","DOI":"10.1200\/JCO.2014.59.5728","volume":"33","author":"G Bougeard","year":"2015","unstructured":"Bougeard G, Renaux-Petel M, Flaman JM et al (2015) Revisiting Li-Fraumeni syndrome from TP53 mutation carriers. J Clin Oncol 33(21):2345\u20132352","journal-title":"J Clin Oncol"}],"container-title":["Brain Tumor Pathology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s10014-024-00489-6.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s10014-024-00489-6\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s10014-024-00489-6.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,10,23]],"date-time":"2024-10-23T20:28:24Z","timestamp":1729715304000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s10014-024-00489-6"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,9,8]]},"references-count":18,"journal-issue":{"issue":"3-4","published-print":{"date-parts":[[2024,10]]}},"alternative-id":["489"],"URL":"https:\/\/doi.org\/10.1007\/s10014-024-00489-6","relation":{},"ISSN":["1433-7398","1861-387X"],"issn-type":[{"value":"1433-7398","type":"print"},{"value":"1861-387X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,9,8]]},"assertion":[{"value":"2 March 2024","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"20 August 2024","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"8 September 2024","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"The authors declare no potential conflicts of interest with respect to the research, authorship, and\/or publication of this article.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflicts of interest"}}]}}