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Pathologic evaluation showed distal transverse shortening, tapering to a point in the mid-forearm. Five primitive digital nubbins were present, located just proximal to the tapered point. The arm vessels appeared normal histologically, and the amnion showed no evidence of intrauterine disruption. Histologic examination of the nubbins revealed osteocartilaginous tissue, never described previously within digital nubbins. This fetus has the rare phenotype of terminal transverse limb defects with residual nubbins, but differs in that the nubbins are not at the tip of the terminal transverse limb defect. <\/jats:p>","DOI":"10.1007\/s10024-002-0112-z","type":"journal-article","created":{"date-parts":[[2003,12,2]],"date-time":"2003-12-02T21:39:20Z","timestamp":1070401160000},"page":"348-354","source":"Crossref","is-referenced-by-count":10,"title":["Unilateral Transverse Arm Defect with Subterminal Digital Nubbins"],"prefix":"10.1177","volume":"6","author":[{"given":"Ronny I.","family":"Drapkin","sequence":"first","affiliation":[{"name":"Department of Pathology, Brigham and Women's Hospital, 75 Francis Street, Boston, MA 02115, USA"},{"name":"Department of Pathology, Harvard Medical School, Boston, MA, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"David R.","family":"Genest","sequence":"additional","affiliation":[{"name":"Department of Pathology, Brigham and Women's Hospital, 75 Francis Street, Boston, MA 02115, USA"},{"name":"Department of Pathology, Harvard Medical School, Boston, MA, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lewis B.","family":"Holmes","sequence":"additional","affiliation":[{"name":"Genetics and Teratology Unit, Pediatric Service, Massachusetts General Hospital, Boston, MA, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Taosheng","family":"Huang","sequence":"additional","affiliation":[{"name":"Division of Genetics and Metabolism, Children's Hospital, Boston, MA, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sara O.","family":"Vargas","sequence":"additional","affiliation":[{"name":"Department of Pathology, Brigham and Women's Hospital, 75 Francis Street, Boston, MA 02115, USA"},{"name":"Department of Pathology, Harvard Medical School, Boston, MA, USA"},{"name":"Department of Pathology, Children's Hospital, 300 Longwood Avenue, Boston, MA 02115, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2003,7,1]]},"reference":[{"key":"bibr1-s10024-002-0112-z","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.96.6.2919"},{"key":"bibr2-s10024-002-0112-z","doi-asserted-by":"publisher","DOI":"10.1016\/S0959-437X(00)00220-3"},{"key":"bibr3-s10024-002-0112-z","doi-asserted-by":"publisher","DOI":"10.1016\/S0959-437X(00)00101-5"},{"key":"bibr4-s10024-002-0112-z","doi-asserted-by":"crossref","unstructured":"McGuirkCK, WestgateM-N, HolmesLB. 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