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We have separated the cases by skull region and spinal column level, and we discuss the attendant differences in prognosis following treatment by neurosurgery, radiation, and chemotherapy. Light and electron microscopic features can be used to differentiate EFT from other small round blue cell tumors that involve the CNS (central primitive neuroectodermal tumor, lymphoma, etc.). Recent molecular and genetic findings in EFT provide new diagnostic methods. We conclude that EFT involving the CNS and adjacent structures is not so rare as previously stated and that the prognosis is more favorable, as a rule, than for the more common examples arising in the long bones and pelvis.<\/jats:p>","DOI":"10.1007\/s100249910026","type":"journal-article","created":{"date-parts":[[2002,7,25]],"date-time":"2002-07-25T02:40:57Z","timestamp":1027564857000},"page":"203-210","source":"Crossref","is-referenced-by-count":33,"title":["Ewing's Family of Tumors Involving Structures Related to the Central Nervous System: A Review"],"prefix":"10.1177","volume":"3","author":[{"given":"M. Gary","family":"Hadfield","sequence":"first","affiliation":[{"name":"Division of Neuropathology, Medical College of Virginia Campus\/Virginia Commonwealth University, Richmond, VA 23298, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Martha M.","family":"Quezado","sequence":"additional","affiliation":[{"name":"Division of Neuropathology, Medical College of Virginia Campus\/Virginia Commonwealth University, Richmond, VA 23298, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Robert L.","family":"Williams","sequence":"additional","affiliation":[{"name":"Department of Pathology, Medical College of Virginia Campus\/Virginia Commonwealth University, Richmond, VA 23298, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Vivian Y.","family":"Luo","sequence":"additional","affiliation":[{"name":"Department of Pathology, Medical College of Virginia Campus\/Virginia Commonwealth University, Richmond, VA 23298, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2000,5]]},"reference":[{"key":"e_1_2_1_2_2","first-page":"27","article-title":"Peripheral primitive neuroectodermal tumors","volume":"16","author":"Tsokos M.","year":"1992","unstructured":"TsokosM. 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