{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,2]],"date-time":"2026-10-02T15:32:52Z","timestamp":1790955172793,"version":"4.1.0"},"reference-count":22,"publisher":"Springer Science and Business Media LLC","issue":"4","license":[{"start":{"date-parts":[[2024,4,12]],"date-time":"2024-04-12T00:00:00Z","timestamp":1712880000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"},{"start":{"date-parts":[[2024,4,12]],"date-time":"2024-04-12T00:00:00Z","timestamp":1712880000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"}],"funder":[{"DOI":"10.13039\/100009933","name":"Ethicon","doi-asserted-by":"publisher","award":["1472047"],"award-info":[{"award-number":["1472047"]}],"id":[{"id":"10.13039\/100009933","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Hernia"],"abstract":"<jats:title>Abstract<\/jats:title><jats:sec>\n                <jats:title>Purpose<\/jats:title>\n                <jats:p>We assessed clinical outcomes of patients undergoing open hernia repair using STRATAFIX\u2122 Symmetric, a barbed triclosan-coated suture (TCS; Ethicon), versus conventional polydioxanone suture (PDS) for abdominal wall closure.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Methods<\/jats:title>\n                <jats:p>This single-center retrospective cohort study identified patients undergoing hernia repair. The site used PDS from 2013 to 2016 and switched exclusively to barbed TCS in 2017. Outcomes were assessed at 30, 60, and 90\u00a0days. Multivariate regression analyses and Cox proportional hazards models were used.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Results<\/jats:title>\n                <jats:p>Of 821 hernia repairs, 446 used barbed TCS and 375 used conventional PDS. Surgical site infections (SSIs) were significantly less frequent with barbed TCS (60 days, 5.9% vs. 11.4%; <jats:italic>P<\/jats:italic>\u2009=\u20090.0083; 90 days, 5.9% vs. 11.7%; <jats:italic>P<\/jats:italic>\u2009=\u20090.006) and this remained consistent after multivariate adjustment (60 days, OR [95% CI]: 0.5 [0.3\u20130.9]; 90 days, 0.5 [0.3\u20130.9]). Among patients with SSI, deep SSIs were less frequent with barbed TCS (60 days, 9.1% vs. 35.7%; <jats:italic>P<\/jats:italic>\u2009=\u20090.022; 90 days, 9.1% vs. 34.9%; <jats:italic>P<\/jats:italic>\u2009=\u20090.0252). Barbed TCS significantly reduced the risk of perioperative complications (HR [95% CI]: 0.5[0.3\u20130.8]; <jats:italic>P<\/jats:italic>\u2009=\u20090.0058). Hospital length of stay was 2.5\u00a0days shorter with barbed TCS (mean [95% CI]: 5.7[4.9\u20136.6] vs. 8.2[7.3\u20139.1] days; <jats:italic>P<\/jats:italic>\u2009&lt;\u20090.0001). No differences in reoperation rate over time were observed by type of suture (HR[95% CI]:1.3 [0.5\u20133.4]; <jats:italic>P<\/jats:italic>\u2009=\u20090.4793).<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Conclusions<\/jats:title>\n                <jats:p>This study showed that patients who underwent open hernia repair appeared to recover equally well regardless of the suture type. In addition, the use of barbed TCS was associated with significantly reduced risk of perioperative complications and hospital length of stay.<\/jats:p>\n              <\/jats:sec>","DOI":"10.1007\/s10029-024-03012-0","type":"journal-article","created":{"date-parts":[[2024,4,12]],"date-time":"2024-04-12T18:02:36Z","timestamp":1712944956000},"page":"1239-1247","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":8,"title":["Clinical outcomes of triclosan-coated barbed suture in open hernia repair: a retrospective cohort study"],"prefix":"10.1007","volume":"28","author":[{"given":"F.","family":"Berrevoet","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"L.","family":"van Cauteren","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"N.","family":"Gunja","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"suffix":"III","given":"W. A.","family":"Danker","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"N.-D.","family":"Schmitz","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J.","family":"Tomaszewski","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"L.","family":"Stern","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"A.","family":"Chandak","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2024,4,12]]},"reference":[{"key":"3012_CR1","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1007\/s10029-014-1342-5","volume":"19","author":"FE Muysoms","year":"2015","unstructured":"Muysoms FE, Antoniou SA, Bury K et al (2015) European Hernia Society guidelines on the closure of abdominal wall incisions. Hernia 19:1\u201324. https:\/\/doi.org\/10.1007\/s10029-014-1342-5","journal-title":"Hernia"},{"key":"3012_CR2","doi-asserted-by":"publisher","first-page":"e25989","DOI":"10.1097\/md.0000000000025989","volume":"100","author":"S Hempel","year":"2021","unstructured":"Hempel S, Kalauch A, Oehme F et al (2021) Wound complications after primary and repeated midline, transverse and modified Makuuchi incision: a single-center experience in 696 patients. Medicine (Baltimore) 100:e25989. https:\/\/doi.org\/10.1097\/md.0000000000025989","journal-title":"Medicine (Baltimore)"},{"key":"3012_CR3","doi-asserted-by":"publisher","first-page":"239","DOI":"10.1007\/s10029-012-0912-7","volume":"16","author":"F Muysoms","year":"2012","unstructured":"Muysoms F, Campanelli G, Champault GG et al (2012) EuraHS: the development of an international online platform for registration and outcome measurement of ventral abdominal wall hernia repair. 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Dan Med Bull 58:A4322","journal-title":"Dan Med Bull"}],"container-title":["Hernia"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s10029-024-03012-0.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s10029-024-03012-0\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s10029-024-03012-0.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,8,2]],"date-time":"2024-08-02T15:11:39Z","timestamp":1722611499000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s10029-024-03012-0"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,4,12]]},"references-count":22,"journal-issue":{"issue":"4","published-online":{"date-parts":[[2024,8]]}},"alternative-id":["3012"],"URL":"https:\/\/doi.org\/10.1007\/s10029-024-03012-0","relation":{},"ISSN":["1248-9204"],"issn-type":[{"value":"1248-9204","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,4,12]]},"assertion":[{"value":"4 December 2023","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"1 March 2024","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"12 April 2024","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"This was a non-interventional retrospective study. The data obtained from the center for this study was de-identified and did not include any patient identifiers or dates, nor any attempt made to re-identify the patients. This study was approved by the Ethics Committee at University Hospital Gent (Commissie voor medische Ethiek, Universitair Ziekenhuis Gent) with the reference number \u201cBC-09077\u201d.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethics approval and consent to participate"}},{"value":"FB reports consulting fees and honoraria from Johnson & Johnson (Ethicon) and also participated in advisory boards for Johnson & Johnson (Ethicon), Medtronic and Tissium. NG, WAD, NDS, and JT are employees of Johnson & Johnson (Ethicon). AC and LS are employees of Certara (which was contracted by Ethicon to conduct this study).","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of interest"}},{"value":"Not applicable.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Human and animal rights"}},{"value":"For this type of non-interventional retrospective study using de-identified data, formal consent was not required.","order":5,"name":"Ethics","group":{"name":"EthicsHeading","label":"Informed consent"}}]}}