{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,17]],"date-time":"2026-10-17T16:23:53Z","timestamp":1792254233598,"version":"4.4.0"},"reference-count":25,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2025,5,23]],"date-time":"2025-05-23T00:00:00Z","timestamp":1747958400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"},{"start":{"date-parts":[[2025,5,23]],"date-time":"2025-05-23T00:00:00Z","timestamp":1747958400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"}],"funder":[{"name":"Zealand Region"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Hernia"],"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Knowledge of long-term outcomes following elective inguinal hernia mesh-repair in patients with inflammatory bowel disease (IBD) remains limited. Pathophysiological differences between Crohn\u2019s disease (CD) and ulcerative colitis (UC) may influence mesh-related complications and recurrence risk. The primary objective was to assess the reoperation risk for mesh-related complications, and secondarily, recurrence after inguinal hernia mesh-repair in patients with CD and UC. The impact of fistulising disease (intra-abdominal\/perianal) and surgical technique (open\/laparoscopic) on both outcomes was also analysed based on the available data.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>This nationwide cohort study (2007\u20132016) followed IBD patients undergoing elective inguinal hernia mesh-repair to assess risks of reoperation for mesh-related complications or recurrence. Risks were estimated using cumulative incidence and Cox regression analyses.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Among 1,072 patients with IBD (CD\u2009=\u2009264, UC\u2009=\u2009698, IBD-unclassified\u2009=\u2009110), the five-year reoperation risk was 0.5% for mesh-related complications and 5.7% for recurrence. Fistulising disease was present in 6.9% (\n                      <jats:italic>n<\/jats:italic>\n                      \u2009=\u200974) of all patients with IBD: perianal in 95% (\n                      <jats:italic>n<\/jats:italic>\n                      \u2009=\u200970) and intra-abdominal in 5% (\n                      <jats:italic>n<\/jats:italic>\n                      \u2009=\u20094). There were too few mesh-related complications (\n                      <jats:italic>n<\/jats:italic>\n                      \u2009=\u20095) to support statistical analysis of this outcome. Recurrence risk was not significantly affected by IBD subtype: CD (reference), UC (HR\u2009=\u20091.67, 95% CI: 0.77\u20133.64), IBD-U (HR\u2009=\u20090.91, 95% CI: 0.24\u20133.44), or surgical technique: transabdominal preperitoneal (TAPP) (reference), and Lichtenstein (HR\u2009=\u20090.80, 95% CI: 0.43\u20131.47).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>This study suggests that inguinal hernia mesh-repair is also safe among IBD patients regardless of subtype, surgical technique, or perianal fistulation. Similarly, recurrence risk was unaffected by these factors. Limited data prevented conclusions on intra-abdominal fistulising disease as a potential risk-factor for poor surgical outcomes.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1007\/s10029-025-03362-3","type":"journal-article","created":{"date-parts":[[2025,5,23]],"date-time":"2025-05-23T03:47:59Z","timestamp":1747972079000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Long-term outcomes after elective inguinal hernia mesh-repair in patients with inflammatory bowel disease"],"prefix":"10.1007","volume":"29","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-7887-3579","authenticated-orcid":false,"given":"Hans","family":"Lov\u00e9n","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rune","family":"Erichsen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anders","family":"T\u00f8ttrup","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Thue","family":"Bisgaard","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2025,5,23]]},"reference":[{"key":"3362_CR1","doi-asserted-by":"publisher","first-page":"1796","DOI":"10.1093\/IBD\/IZAA020","volume":"26","author":"CCY Law","year":"2020","unstructured":"Law CCY, Koh D, Bao Y et al (2020) Risk of postoperative infectious complications from medical therapies in inflammatory bowel disease: A systematic review and Meta-Analysis. 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