{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,12]],"date-time":"2026-03-12T00:44:12Z","timestamp":1773276252576,"version":"3.50.1"},"reference-count":31,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2026,3,11]],"date-time":"2026-03-11T00:00:00Z","timestamp":1773187200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"},{"start":{"date-parts":[[2026,3,11]],"date-time":"2026-03-11T00:00:00Z","timestamp":1773187200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Hernia"],"DOI":"10.1007\/s10029-026-03632-8","type":"journal-article","created":{"date-parts":[[2026,3,11]],"date-time":"2026-03-11T10:35:21Z","timestamp":1773225321000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["A practical algorithm for the combined use of preoperative progressive pneumoperitoneum and botulinum toxin A in large incisional hernia repair: learnings after 15\u00a0years of experience"],"prefix":"10.1007","volume":"30","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-3116-5022","authenticated-orcid":false,"given":"Jos\u00e9","family":"Bueno-Lled\u00f3","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Omar","family":"Carre\u00f1o-S\u00e1enz","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"David","family":"Quevedo-Cruz","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alba","family":"Serrano-Molina","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jesus","family":"Martinez-Hoed","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Santiago","family":"Bonaf\u00e9-Diana","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Victoria","family":"Pareja-Ibars","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Providencia","family":"Garcia-Pastor","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Salvador","family":"Pous-Serrano","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2026,3,11]]},"reference":[{"key":"3632_CR1","doi-asserted-by":"publisher","first-page":"396","DOI":"10.1007\/s00268-018-4783-7","volume":"43","author":"SG Parker","year":"2019","unstructured":"Parker SG, Halligan S, Blackburn S, Plumb AAO, Archer L, Mallet S et al (2019) What exactly is meant by \u2018loss of domain\u2019 for ventral hernia? Systematic review of definitions. World J Surg 43:396\u2013404. https:\/\/doi.org\/10.1007\/s00268-018-4783-7","journal-title":"World J Surg"},{"key":"3632_CR2","doi-asserted-by":"publisher","first-page":"191","DOI":"10.1007\/s10029-016-1463-0","volume":"20","author":"NN Alam","year":"2016","unstructured":"Alam NN, Narang SK, Pathak S, Daniels IR, Smart NJ (2016) Methods of abdominal wall expansion for repair of incisional herniae: a systematic review. Hernia 20:191\u2013199","journal-title":"Hernia"},{"key":"3632_CR3","doi-asserted-by":"publisher","DOI":"10.1007\/s10029-017-1582-2","author":"J Bueno-Lled\u00f3","year":"2017","unstructured":"Bueno-Lled\u00f3 J, Torregrosa A, Ballester N, Carre\u00f1o O, Carbonell F, Pastor PG et al (2017) Preoperative progressive pneumoperitoneum and botulinum toxin type A in patients with large incisional hernia. Hernia. https:\/\/doi.org\/10.1007\/s10029-017-1582-2","journal-title":"Hernia"},{"key":"3632_CR4","doi-asserted-by":"publisher","first-page":"246","DOI":"10.1007\/s00423-002-0316-8","volume":"387","author":"A Toniato","year":"2002","unstructured":"Toniato A, Pagetta C, Bernante P, Piotto A, Pelizzo MR (2002) Incisional hernia treatment with progressive pneumoperitoneum and retromuscular prosthetic hernioplasty. Langenbecks Arch Surg 387:246\u2013248","journal-title":"Langenbecks Arch Surg"},{"issue":"6","key":"3632_CR5","doi-asserted-by":"publisher","first-page":"1443","DOI":"10.1007\/s10029-020-02247-x","volume":"25","author":"J Mart\u00ednez-Hoed","year":"2021","unstructured":"Mart\u00ednez-Hoed J, Bonafe-Diana S, Bueno-Lled\u00f3 J (2021) A systematic review of the use of progressive preoperative pneumoperitoneum since its inception. Hernia 25(6):1443\u20131458","journal-title":"Hernia"},{"issue":"3","key":"3632_CR6","doi-asserted-by":"publisher","first-page":"665","DOI":"10.1007\/s10029-023-02892-y","volume":"28","author":"VRD Barretto","year":"2024","unstructured":"Barretto VRD, de Oliveira JGR, Brim ACS, Ara\u00fajo RBS, Barros RA, Romeo ALB (2024) Botulinum toxin A in complex incisional hernia repair: a systematic review. Hernia 28(3):665\u2013676. https:\/\/doi.org\/10.1007\/s10029-023-02892-y","journal-title":"Hernia"},{"key":"3632_CR7","doi-asserted-by":"publisher","first-page":"63","DOI":"10.1007\/s10029-009-0560-8","volume":"14","author":"EY Tanaka","year":"2010","unstructured":"Tanaka EY, Yoo JH, Rodrigues AJ Jr, Ultiyama EM, Birolini D, Rasslan S (2010) Computerized tomography scan method for calculating the hernia sac and abdominal cavity volume in complex large incisional hernia with loss of domain. Hernia 14:63\u201369","journal-title":"Hernia"},{"key":"3632_CR8","doi-asserted-by":"publisher","first-page":"407","DOI":"10.1007\/s10029-009-0518-x","volume":"13","author":"FE Muysoms","year":"2009","unstructured":"Muysoms FE, Miserez M, Berrevoet F et al (2009) Classification of primary and incisional abdominal wall hernias. Hernia 13:407\u2013414","journal-title":"Hernia"},{"key":"3632_CR9","doi-asserted-by":"publisher","first-page":"2553","DOI":"10.1007\/s00268-009-0203-3","volume":"33","author":"TR Ibarra-Hurtado","year":"2009","unstructured":"Ibarra-Hurtado TR, Nu\u00f1o-Guzm\u00e1n CM, Echeagaray-Herrera JE, Robles-Velez E, de Jesus Gonzalez-Jaime J (2009) Use of botulinum toxin type A before abdominal wall hernia reconstruction. World J Surg 33:2553\u20132556","journal-title":"World J Surg"},{"key":"3632_CR10","doi-asserted-by":"publisher","first-page":"205","DOI":"10.1097\/01.sla.0000133083.54934.ae","volume":"240","author":"D Dindo","year":"2004","unstructured":"Dindo D, Demartines N, Clavien PA (2004) Classification of surgical complications. A new proposal with evaluation in a cohort of 6336 patients and results of a survey. Ann Surg 240:205\u2013213","journal-title":"Ann Surg"},{"key":"3632_CR11","doi-asserted-by":"publisher","first-page":"647","DOI":"10.1007\/s10029-014-1280-2","volume":"18","author":"T Ibarra-Hurtado","year":"2014","unstructured":"Ibarra-Hurtado T, Nu\u00f1o-Guzman C, Miranda AG, Troyo R, Navarro R, Bravo L (2014) Effect of botulinum toxin type A in lateral abdominal wall muscles thickness and length of patients with midline incisional hernia secondary to open abdomen management. Hernia 18:647\u2013652","journal-title":"Hernia"},{"key":"3632_CR12","doi-asserted-by":"publisher","first-page":"101","DOI":"10.1007\/s10029-012-0995-1","volume":"17","author":"M Zielinski","year":"2013","unstructured":"Zielinski M, Goussous N, Schiller H (2013) Chemical components separation with botulinum toxin A: a novel technique to improve primary fascial closure rates of the open abdomen. Hernia 17:101\u2013107","journal-title":"Hernia"},{"issue":"1","key":"3632_CR13","doi-asserted-by":"publisher","first-page":"55","DOI":"10.1016\/j.jviscsurg.2021.06.009","volume":"159","author":"M Tenaudier","year":"2022","unstructured":"Tenaudier M, Moszkowicz D, Passot G, Romain B, Perrenot C, Borraccino B et al (2022) Botulinum toxin injection before giant incisional hernia repair: surgical technique. J Visc Surg 159(1):55\u201358. https:\/\/doi.org\/10.1016\/j.jviscsurg.2021.06.009","journal-title":"J Visc Surg"},{"issue":"8","key":"3632_CR14","doi-asserted-by":"publisher","first-page":"3599","DOI":"10.1007\/s00464-018-6089-0","volume":"32","author":"J Bueno-Lled\u00f3","year":"2018","unstructured":"Bueno-Lled\u00f3 J, Torregrosa A, Jim\u00e9nez-Rosell\u00f3n R, Pastor-Garc\u00eda P (2018) Preoperative combination of progressive pneumoperito- neum and botulinum toxin type A in patients with loss of domain hernia. Surg Endosc 32(8):3599\u20133608. https:\/\/doi.org\/10.1007\/s00464-018-6089-0","journal-title":"Surg Endosc"},{"issue":"10","key":"3632_CR15","doi-asserted-by":"publisher","DOI":"10.7759\/cureus.94178","volume":"17","author":"MA Chinikov","year":"2025","unstructured":"Chinikov MA, Othman H, Keshishyan RA, Al-Ariki MK, Saghir H, Sidik AI (2025) Reducing transversus abdominis release hernioplasty operative volume using preoperative botulinum toxin injections. Cureus 17(10):e94178. https:\/\/doi.org\/10.7759\/cureus.94178","journal-title":"Cureus"},{"issue":"7","key":"3632_CR16","doi-asserted-by":"publisher","DOI":"10.1016\/j.cireng.2025.800117","volume":"103","author":"S Argudo Garijo","year":"2025","unstructured":"Argudo Garijo S, Jim\u00e9nez Jim\u00e9nez FJ, Ram\u00edrez Calder\u00f3n J, Jullien Petrelli AC, Del Corral Rodr\u00edguez J, Hern\u00e1ndez Garc\u00eda M et al (2025) Study of morphological changes observed on abdominal CT scan after preoperative treatment with botulinum toxin type A in patients with midline incisional hernias or lateral component. Cirug\u00eda Espa\u00f1ola (English Edition) 103(7):800117. https:\/\/doi.org\/10.1016\/j.cireng.2025.800117","journal-title":"Cirug\u00eda Espa\u00f1ola (English Edition)"},{"issue":"3","key":"3632_CR17","doi-asserted-by":"publisher","first-page":"543","DOI":"10.1016\/j.surg.2020.04.050","volume":"168","author":"J Bueno-Lled\u00f3","year":"2020","unstructured":"Bueno-Lled\u00f3 J, Martinez-Hoed J, Torregrosa-Gallud A, Men\u00e9ndez-Jim\u00e9nez M, Pous-Serrano S (2020) Botulinum\u00a0toxin\u00a0to\u00a0avoid\u00a0component separation in midline large hernias. Surgery 168(3):543\u2013549. https:\/\/doi.org\/10.1016\/j.surg.2020.04.050","journal-title":"Surgery"},{"issue":"1","key":"3632_CR18","doi-asserted-by":"publisher","first-page":"96","DOI":"10.1007\/s10029-025-03290-2","volume":"29","author":"ME Polcz","year":"2025","unstructured":"Polcz ME, Holland AM, Lorenz WR, Ayuso S, Scarola GT, Ku D et al (2025) Preoperative botulinum toxin A (BTA) injection in abdominal wall reconstruction for subxiphoid (M1) hernias. Hernia 29(1):96. https:\/\/doi.org\/10.1007\/s10029-025-03290-2","journal-title":"Hernia"},{"issue":"7","key":"3632_CR19","doi-asserted-by":"publisher","first-page":"391","DOI":"10.1016\/j.cireng.2023.12.003","volume":"102","author":"S Pous-Serrano","year":"2024","unstructured":"Pous-Serrano S, Bueno-Lled\u00f3 J, Garc\u00eda-Pastor P, Carre\u00f1o-S\u00e1enz O, Pareja-Ibars V, Bonaf\u00e9-Diana S et al (2024) Use of botulinum toxin type A in the prehabilitation of abdominal wall musculature for hernia repair: a consensus proposal. Cirug\u00eda Espa\u00f1ola (English Edition) 102(7):391\u2013399. https:\/\/doi.org\/10.1016\/j.cireng.2023.12.003","journal-title":"Cirug\u00eda Espa\u00f1ola (English Edition)"},{"key":"3632_CR20","first-page":"945","volume":"22","author":"I Go\u00f1i-Moreno","year":"1947","unstructured":"Go\u00f1i-Moreno I (1947) Chronic eventrations and large hernias: preoperative treatment by progressive pneumoperitoneum\u2014original procedure. Surgery 22:945\u2013953","journal-title":"Surgery"},{"key":"3632_CR21","doi-asserted-by":"publisher","first-page":"213","DOI":"10.1007\/s10029-005-0040-8","volume":"10","author":"JC Mayagoitia","year":"2006","unstructured":"Mayagoitia JC, Suarez D, Arenas JC, de Diaz Leon V (2006) Preoperative progressive pneumoperitoneum in patients with abdominal-wall hernias. Hernia 10:213\u2013217","journal-title":"Hernia"},{"issue":"6","key":"3632_CR22","doi-asserted-by":"publisher","first-page":"1507","DOI":"10.1007\/s10029-021-02387-8","volume":"25","author":"A Tashkandi","year":"2021","unstructured":"Tashkandi A, Bueno-Lled\u00f3 J, Durtette-Guzylack J, Cayeux A, Bukhari R, Rhaeim R et al (2021) Adjunct botox to preoperative\u00a0progressive\u00a0pneumoperitoneum\u00a0for incisional hernia with loss of domain: no additional effect but may improve outcomes. Hernia 25(6):1507\u20131517","journal-title":"Hernia"},{"key":"3632_CR23","first-page":"664","volume":"109","author":"V Oprea","year":"2014","unstructured":"Oprea V, Matei O, Gheorghescu D, Leuca D, Buia F, Rosianu M et al (2014) Progressive preoperative pneumoperitoneum (PPP) as an adjunct for surgery of hernias with loss of domain. Chirugia 109:664\u2013669","journal-title":"Chirugia"},{"key":"3632_CR24","doi-asserted-by":"publisher","first-page":"33","DOI":"10.1007\/s10029-011-0849-2","volume":"16","author":"C Sabbagh","year":"2012","unstructured":"Sabbagh C, Dumont F, Fuks D, Yzet T, Vernaeghe P, Regimbeau JM (2012) Progressive preoperative pneumoperitoneum preparation (the Goni Moreno protocol) prior to large incisional hernia surgery: volumetric, respiratory and clinical impacts. A prospective study. Hernia 16:33\u201340","journal-title":"Hernia"},{"key":"3632_CR25","doi-asserted-by":"publisher","first-page":"426","DOI":"10.1016\/j.surg.2016.03.033","volume":"160","author":"Y Renard","year":"2016","unstructured":"Renard Y, Lardi\u00e8re-Deguelte S, de Mestier L, Appere F, Colosio A, Kianmanesh R et al (2016) Management of large incisional hernias with loss of domain: a prospective series of patients prepared by progressive preoperative pneumoperitoneum. Surgery 160:426\u2013435","journal-title":"Surgery"},{"issue":"8","key":"3632_CR26","doi-asserted-by":"publisher","first-page":"754543","DOI":"10.3389\/fsurg.2021.754543","volume":"18","author":"K Elstner","year":"2021","unstructured":"Elstner K, Moolan Y, Chen E, Jacombs A, Rodriguez-Acevedo O, Ibrahim N et al (2021) Preoperative progressive pneumoperitoneum revisited. Front Surg 18(8):754543","journal-title":"Front Surg"},{"key":"3632_CR27","doi-asserted-by":"publisher","first-page":"559","DOI":"10.1007\/s10029-011-0832-y","volume":"15","author":"C Sabbagh","year":"2011","unstructured":"Sabbagh C, Dumont F, Robert B, Badaoui R, Verhaehe P, Regimbeau JM (2011) Peritoneal volume is predictive of tensionfree fascia closure of large incisional hernias with loss of domain: a prospective study. Hernia 15:559\u2013565","journal-title":"Hernia"},{"issue":"5","key":"3632_CR28","doi-asserted-by":"publisher","first-page":"1591","DOI":"10.1007\/s10029-023-02836-6","volume":"28","author":"J Bueno-Lled\u00f3","year":"2024","unstructured":"Bueno-Lled\u00f3 J, Mart\u00ednez-Hoed J, Bonaf\u00e9-Diana S, Garc\u00eda-Pastor P, Torregrosa-Gallud A, Pareja-Ibars V et al (2024) Complications related to the prehabilitation with preoperative pneumoperitoneum in loss of domain hernias: our experience in 180 consecutive cases. Hernia 28(5):1591\u20131598","journal-title":"Hernia"},{"issue":"1","key":"3632_CR29","doi-asserted-by":"publisher","first-page":"207","DOI":"10.1007\/s10029-025-03401-z","volume":"29","author":"AA Abbas","year":"2025","unstructured":"Abbas AA, Ahmad A, McCleary A, Nicholls M, Chitsabesan P, Chintapatla S (2025) A structured protocol for preoperative progressive pneumoperitoneum (PPP) in complex abdominal wall reconstruction (CAWR): our York protocol. Hernia 29(1):207. https:\/\/doi.org\/10.1007\/s10029-025-03401-z","journal-title":"Hernia"},{"issue":"12","key":"3632_CR30","doi-asserted-by":"publisher","first-page":"1732","DOI":"10.1093\/bjs\/znad284","volume":"110","author":"DL Sanders","year":"2023","unstructured":"Sanders DL, Pawlak MM, Simons MP, Aufenacker T, Balla A, Berger C et al (2023) Midline incisional hernia guidelines: the European Hernia Society. Br J Surg 110(12):1732\u20131768. https:\/\/doi.org\/10.1093\/bjs\/znad284","journal-title":"Br J Surg"},{"issue":"10","key":"3632_CR31","doi-asserted-by":"publisher","DOI":"10.1016\/j.cireng.2025.800212","volume":"103","author":"S Pous-Serrano","year":"2025","unstructured":"Pous-Serrano S, Bueno-Lled\u00f3 J, Mart\u00ednez-Hoed J, Carre\u00f1o-S\u00e1enz O, Garc\u00eda-Pastor P, Bonaf\u00e9-Diana S et al (2025) Conditioning of the abdominal wall with progressive pneumoperitoneum in hernias with loss of domain. A consensus proposal. Cirug\u00eda Espa\u00f1ola (English Edition) 103(10):800212. https:\/\/doi.org\/10.1016\/j.cireng.2025.800212","journal-title":"Cirug\u00eda Espa\u00f1ola (English Edition)"}],"container-title":["Hernia"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s10029-026-03632-8.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s10029-026-03632-8","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s10029-026-03632-8.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,3,11]],"date-time":"2026-03-11T10:35:21Z","timestamp":1773225321000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s10029-026-03632-8"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,3,11]]},"references-count":31,"journal-issue":{"issue":"1","published-online":{"date-parts":[[2026,12]]}},"alternative-id":["3632"],"URL":"https:\/\/doi.org\/10.1007\/s10029-026-03632-8","relation":{},"ISSN":["1248-9204"],"issn-type":[{"value":"1248-9204","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,3,11]]},"assertion":[{"value":"12 December 2025","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"15 February 2026","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"11 March 2026","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"Authors declare that a written informed consent was obtained from all patients.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethics statement"}},{"value":"All other authors declare no disclosures relevant to this article or research, and have no conflicts of interest or financial ties to disclose.The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of interest"}}],"article-number":"122"}}