{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,14]],"date-time":"2026-07-14T00:13:58Z","timestamp":1783988038894,"version":"3.55.0"},"reference-count":16,"publisher":"Springer Science and Business Media LLC","issue":"4","license":[{"start":{"date-parts":[[2022,3,18]],"date-time":"2022-03-18T00:00:00Z","timestamp":1647561600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springer.com\/tdm"},{"start":{"date-parts":[[2022,3,18]],"date-time":"2022-03-18T00:00:00Z","timestamp":1647561600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springer.com\/tdm"}],"funder":[{"name":"Nipro Co."},{"name":"Nikkiso Co."},{"name":"Asahi-Kasei Co."}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["J Artif Organs"],"published-print":{"date-parts":[[2022,12]]},"DOI":"10.1007\/s10047-022-01321-8","type":"journal-article","created":{"date-parts":[[2022,3,18]],"date-time":"2022-03-18T12:04:53Z","timestamp":1647605093000},"page":"336-342","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":5,"title":["Novel substitution technique in intermittent infusion hemodiafiltration (I-HDF) therapy using back filtration as substitution"],"prefix":"10.1007","volume":"25","author":[{"given":"Masaya","family":"Watanabe","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Takayoshi","family":"Kiguchi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0347-8742","authenticated-orcid":false,"given":"Akihiro C.","family":"Yamashita","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2022,3,18]]},"reference":[{"key":"1321_CR1","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1159\/000503878","volume":"48","author":"Y Koda","year":"2019","unstructured":"Koda Y, Aoike I. Prevention of intradialytic hypotension with intermittent back-filtrate infusion haemodiafiltration insights into the underlying mechanism. Blood Purify. 2019;48:1\u20136. https:\/\/doi.org\/10.1159\/000503878.","journal-title":"Blood Purify"},{"key":"1321_CR2","doi-asserted-by":"publisher","first-page":"769","DOI":"10.4009\/jsdt.40.769","volume":"40","author":"K Eguchi","year":"2007","unstructured":"Eguchi K, Ikebe N, Konno Y, Yamada Y, Kaneko I, Mineshima M, Akiba T. Development and clinical effectiveness of intermittent infusion hemodiafiltration (I-HDF) as a new HDF therapy (in Japanese). J Jpn Soc Dial Ther. 2007;40:769\u201374. https:\/\/doi.org\/10.4009\/jsdt.40.769 (https:\/\/ci.nii.ac.jp\/lognavi?name=crossref&id=info).","journal-title":"J Jpn Soc Dial Ther"},{"key":"1321_CR3","doi-asserted-by":"publisher","first-page":"55","DOI":"10.1159\/000346371","volume":"35","author":"M Mineshima","year":"2013","unstructured":"Mineshima M, Eguchi K. Development of intermittent infusion hemodiafiltration using ultrapure dialysis fluid with an automated dialysis machine. Blood Purify. 2013;35:55\u20138. https:\/\/doi.org\/10.1159\/000346371.","journal-title":"Blood Purify"},{"key":"1321_CR4","doi-asserted-by":"publisher","first-page":"7","DOI":"10.1159\/000503891","volume":"48","author":"M Mineshima","year":"2019","unstructured":"Mineshima M, Eguchi K. Validity of intermittent infusion hemodiafiltration. Blood Purify. 2019;48:7\u201310. https:\/\/doi.org\/10.1159\/000503891.","journal-title":"Blood Purify"},{"key":"1321_CR5","doi-asserted-by":"publisher","first-page":"27","DOI":"10.1159\/000503892","volume":"48","author":"S Otsubo","year":"2019","unstructured":"Otsubo S, Eguchi K, Mineshima M, Tsuchiya K, Nitta K. Relationship between dose of bolus dialysate infusion and blood pressure in intermittent infusion hemodiafiltration. Blood Purify. 2019;48:27\u201332. https:\/\/doi.org\/10.1159\/000503892.","journal-title":"Blood Purify"},{"key":"1321_CR6","doi-asserted-by":"publisher","first-page":"68","DOI":"10.1016\/j.cmpb.2012.01.001","volume":"108","author":"JC Leea","year":"2012","unstructured":"Leea JC, Leeb K, Kim HC. Mathematical analysis for internal filtration of convection-enhanced high-flux hemodialyzer. Comput Methods Programs Biomed. 2012;108:68\u201379. https:\/\/doi.org\/10.1016\/j.cmpb.2012.01.001.","journal-title":"Comput Methods Programs Biomed"},{"key":"1321_CR7","doi-asserted-by":"publisher","first-page":"809","DOI":"10.1046\/j.1523-1755.2000.00230.x","volume":"58","author":"C Ronco","year":"2000","unstructured":"Ronco C, Brendolan A, Lupi A, Metry G, Levin NW. Effects of a reduced inner diameter of hollow fibers in hemodialyzers. Kidney Int. 2000;58:809\u201317. https:\/\/doi.org\/10.1046\/j.1523-1755.2000.00230.x.","journal-title":"Kidney Int"},{"key":"1321_CR8","doi-asserted-by":"publisher","first-page":"181","DOI":"10.1016\/S0376-7388(97)00044-6","volume":"131","author":"A Wfipper","year":"1997","unstructured":"Wfipper A, Dellanna F, Baldamus CA, Woermann D. Local transport processes in high-flux hollow fiber dialyzers. J Membr Sci. 1997;131:181\u201393. https:\/\/doi.org\/10.1016\/S0376-7388(97)00044-6.","journal-title":"J Membr Sci"},{"key":"1321_CR9","doi-asserted-by":"publisher","first-page":"S2","DOI":"10.1111\/j.1542-4758.2009.00411.x","volume":"13","author":"AC Yamashita","year":"2009","unstructured":"Yamashita AC, Fujita R, Tomisawa N, jinbo Y, Yamamura M. Effect of packing density of hollow fibers on solute removal performances of dialyzers. Hemodial Int. 2009;13:S2\u20137. https:\/\/doi.org\/10.1111\/j.1542-4758.2009.00411.x.","journal-title":"Hemodial Int"},{"key":"1321_CR10","doi-asserted-by":"publisher","first-page":"95","DOI":"10.1159\/000328946","volume":"173","author":"AC Yamashita","year":"2011","unstructured":"Yamashita AC. Mass transfer mechanisms in high-performance membrane dialyzers. Contrib Nephrol Basel: Karger. 2011;173:95\u2013109. https:\/\/doi.org\/10.1159\/000328946.","journal-title":"Contrib Nephrol Basel: Karger"},{"key":"1321_CR11","doi-asserted-by":"publisher","first-page":"456","DOI":"10.1097\/00002480-200007000-00018","volume":"46","author":"M Mineshima","year":"2000","unstructured":"Mineshima M, Ishimori I, Ishida K, Hoshino T, Kaneko I, Sato Y, Agishi T, Tamamura N, Sakurai H, Masuda T, Hattori H. Effect of internal filtration on the solute removal efficiency of a dialyzer. ASAIO J. 2000;46:456\u201360. https:\/\/doi.org\/10.1097\/00002480-200007000-00018.","journal-title":"ASAIO J"},{"key":"1321_CR12","first-page":"304","volume":"33","author":"TL Pallone","year":"1987","unstructured":"Pallone TL, Peterson J. A mathematical of continuous arteriovenous Hemofiltration predicts performance. Trans Am Soc Artif Intern Organs. 1987;33:304\u20138.","journal-title":"Trans Am Soc Artif Intern Organs"},{"key":"1321_CR13","doi-asserted-by":"publisher","first-page":"229","DOI":"10.1016\/0006-3002(58)90330-5","volume":"27","author":"O Kedem","year":"1958","unstructured":"Kedem O, Katchalsky A. Thermodynamic analysis of the permeability of biological membranes to non-electrolytes. Biochem Biophys Acta. 1958;27:229\u201346. https:\/\/doi.org\/10.1016\/0006-3002(58)90330-5.","journal-title":"Biochem Biophys Acta"},{"key":"1321_CR14","first-page":"961","volume":"2","author":"EM Landis","year":"1963","unstructured":"Landis EM, Pappenheimer JR. Exchange of substances through the capillary walls. Handb Physiol Sect2 Circ. 1963;2:961\u20131034.","journal-title":"Handb Physiol. Sect.2 Circ"},{"key":"1321_CR15","doi-asserted-by":"publisher","first-page":"555","DOI":"10.1159\/000097079","volume":"24","author":"GB Fiore","year":"2006","unstructured":"Fiore GB, Guadagni G, Lupi A, Ricci Z, Ronco C. A new semiempirical mathematical model for prediction of internal filtration in hollow fiber hemodialyzers. Blood Purify. 2006;24:555\u201368. https:\/\/doi.org\/10.1159\/000097079.","journal-title":"Blood Purify"},{"key":"1321_CR16","first-page":"1643","volume":"2","author":"LW Henderson","year":"1976","unstructured":"Henderson LW. Hemodialysis: rationale and physical principles. The kidney edited by GM Brenner and FC rector. Phila WB Saunders. 1976;2:1643\u201371.","journal-title":"Phila. WB Saunders"}],"container-title":["Journal of Artificial Organs"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s10047-022-01321-8.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s10047-022-01321-8\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s10047-022-01321-8.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,11,8]],"date-time":"2022-11-08T22:07:57Z","timestamp":1667945277000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s10047-022-01321-8"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,3,18]]},"references-count":16,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2022,12]]}},"alternative-id":["1321"],"URL":"https:\/\/doi.org\/10.1007\/s10047-022-01321-8","relation":{},"ISSN":["1434-7229","1619-0904"],"issn-type":[{"value":"1434-7229","type":"print"},{"value":"1619-0904","type":"electronic"}],"subject":[],"published":{"date-parts":[[2022,3,18]]},"assertion":[{"value":"24 September 2021","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"22 February 2022","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"18 March 2022","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"Akihiro C. Yamashita is serving as a consultant for Nikkiso Co., Tokyo, Japan. Takayoshi Kiguchi has no conflict of interest. Masaya Watanabe has no conflict of interest.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of interest"}}]}}