{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,24]],"date-time":"2026-06-24T11:38:21Z","timestamp":1782301101470,"version":"3.54.5"},"reference-count":49,"publisher":"Springer Science and Business Media LLC","issue":"3","license":[{"start":{"date-parts":[[2025,4,25]],"date-time":"2025-04-25T00:00:00Z","timestamp":1745539200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"},{"start":{"date-parts":[[2025,4,25]],"date-time":"2025-04-25T00:00:00Z","timestamp":1745539200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["J Artif Organs"],"published-print":{"date-parts":[[2025,9]]},"DOI":"10.1007\/s10047-025-01501-2","type":"journal-article","created":{"date-parts":[[2025,4,24]],"date-time":"2025-04-24T23:07:18Z","timestamp":1745536038000},"page":"431-438","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Admission hematocrit and fluctuating blood urea nitrogen levels predict the efficacy of blood purification treatment in severe acute pancreatitis patients"],"prefix":"10.1007","volume":"28","author":[{"given":"Bibi","family":"Chen","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Junhuang","family":"Chen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Handong","family":"Huang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Liqun","family":"Yan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ling","family":"Lin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hongwei","family":"Huang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2025,4,25]]},"reference":[{"issue":"20","key":"1501_CR1","doi-asserted-by":"publisher","first-page":"6304","DOI":"10.3748\/wjg.v21.i20.6304","volume":"21","author":"HL Wang","year":"2015","unstructured":"Wang HL, Yu KJ. Sequential blood purification therapy for critical patients with hyperlipidemic severe acute pancreatitis. World J Gastroenterol. 2015;21(20):6304\u20139.","journal-title":"World J Gastroenterol"},{"key":"1501_CR2","doi-asserted-by":"publisher","first-page":"8236616","DOI":"10.1155\/2024\/8236616","volume":"2024","author":"J Li","year":"2024","unstructured":"Li J, Gao J, Huang M, Fu X, Fu B. Risk factors for death in patients with severe acute pancreatitis in Guizhou Province. China Gastroenterol Res Pract. 2024;2024:8236616.","journal-title":"China Gastroenterol Res Pract"},{"issue":"38","key":"1501_CR3","doi-asserted-by":"publisher","first-page":"13879","DOI":"10.3748\/wjg.v20.i38.13879","volume":"20","author":"E Zerem","year":"2014","unstructured":"Zerem E. Treatment of severe acute pancreatitis and its complications. World J Gastroenterol. 2014;20(38):13879\u201392.","journal-title":"World J Gastroenterol"},{"issue":"1","key":"1501_CR4","doi-asserted-by":"publisher","first-page":"81","DOI":"10.1186\/s12876-023-02730-6","volume":"23","author":"NJ Hidalgo","year":"2023","unstructured":"Hidalgo NJ, Pando E, Mata R, Fernandes N, Villasante S, Barros M, et al. Impact of comorbidities on hospital mortality in patients with acute pancreatitis: a population-based study of 110,021 patients. BMC Gastroenterol. 2023;23(1):81.","journal-title":"BMC Gastroenterol"},{"issue":"11","key":"1501_CR5","doi-asserted-by":"publisher","first-page":"2570","DOI":"10.3748\/wjg.v9.i11.2570","volume":"9","author":"AJ Zhu","year":"2003","unstructured":"Zhu AJ, Shi JS, Sun XJ. Organ failure associated with severe acute pancreatitis. World J Gastroenterol. 2003;9(11):2570\u20133.","journal-title":"World J Gastroenterol"},{"issue":"35","key":"1501_CR6","doi-asserted-by":"publisher","first-page":"8276","DOI":"10.12998\/wjcc.v11.i35.8276","volume":"11","author":"S Li","year":"2023","unstructured":"Li S, Yin D, Guo XC. Influence of standardized nursing intervention combined with mindfulness stress reduction training on the curative effect in patients with acute pancreatitis. World J Clin Cases. 2023;11(35):8276\u201383.","journal-title":"World J Clin Cases"},{"issue":"8","key":"1501_CR7","doi-asserted-by":"publisher","first-page":"1974","DOI":"10.3390\/diagnostics12081974","volume":"12","author":"J Walkowska","year":"2022","unstructured":"Walkowska J, Zielinska N, Tubbs RS, Podg\u00f3rski M, D\u0142ubek-Ruxer J, Olewnik \u0141. Diagnosis and treatment of acute pancreatitis. Diagnostics (Basel). 2022;12(8):1974.","journal-title":"Diagnostics (Basel)"},{"issue":"12","key":"1501_CR8","doi-asserted-by":"publisher","DOI":"10.1097\/MD.0000000000014873","volume":"98","author":"Y Hu","year":"2019","unstructured":"Hu Y, Xiong W, Li C, Cui Y. Continuous blood purification for severe acute pancreatitis: a systematic review and meta-analysis. Medicine (Baltimore). 2019;98(12): e14873.","journal-title":"Medicine (Baltimore)"},{"issue":"3","key":"1501_CR9","doi-asserted-by":"publisher","first-page":"221","DOI":"10.1159\/000448500","volume":"42","author":"JA Kellum","year":"2016","unstructured":"Kellum JA, Ronco C. The 17th acute disease quality initiative international consensus conference: introducing precision renal replacement therapy. Blood Purif. 2016;42(3):221\u20133.","journal-title":"Blood Purif"},{"issue":"9","key":"1501_CR10","doi-asserted-by":"publisher","first-page":"1279","DOI":"10.6004\/jnccn.2020.7595","volume":"18","author":"AT Kuykendall","year":"2020","unstructured":"Kuykendall AT, Komrokji R. What\u2019s in a number? Examining the prognostic and predictive importance of platelet count in patients with essential thrombocythemia. J Natl Compr Canc Netw. 2020;18(9):1279\u201384.","journal-title":"J Natl Compr Canc Netw"},{"issue":"9","key":"1501_CR11","doi-asserted-by":"publisher","first-page":"1649","DOI":"10.1111\/jgh.13763","volume":"32","author":"F Valverde-L\u00f3pez","year":"2017","unstructured":"Valverde-L\u00f3pez F, Matas-Cobos AM, Alegr\u00eda-Motte C, Jim\u00e9nez-Rosales R, \u00dabeda-Mu\u00f1oz M, Redondo-Cerezo E. BISAP, RANSON, lactate, and others biomarkers in prediction of severe acute pancreatitis in a European cohort. J Gastroenterol Hepatol. 2017;32(9):1649\u201356.","journal-title":"J Gastroenterol Hepatol"},{"key":"1501_CR12","doi-asserted-by":"publisher","DOI":"10.1155\/2013\/367581","volume":"2013","author":"AK Khanna","year":"2013","unstructured":"Khanna AK, Meher S, Prakash S, Tiwary SK, Singh U, Srivastava A, et al. Comparison of ranson, glasgow, MOSS, SIRS, BISAP, APACHE-II, CTSI scores, IL-6, CRP, and procalcitonin in predicting severity, organ failure, pancreatic necrosis, and mortality in acute pancreatitis. HPB Surg. 2013;2013: 367581.","journal-title":"HPB Surg"},{"issue":"11","key":"1501_CR13","doi-asserted-by":"publisher","first-page":"1895","DOI":"10.1111\/jgh.13803","volume":"32","author":"WH He","year":"2017","unstructured":"He WH, Zhu Y, Zhu Y, Jin Q, Xu HR, Xion ZJ, et al. Comparison of multifactor scoring systems and single serum markers for the early prediction of the severity of acute pancreatitis. J Gastroenterol Hepatol. 2017;32(11):1895\u2013901.","journal-title":"J Gastroenterol Hepatol"},{"issue":"3","key":"1501_CR14","doi-asserted-by":"publisher","first-page":"363","DOI":"10.1097\/MPA.0000000000001265","volume":"48","author":"DS Vitale","year":"2019","unstructured":"Vitale DS, Hornung L, Lin TK, Nathan JD, Prasad S, Thompson T, et al. Blood urea nitrogen elevation is a marker for pediatric severe acute pancreatitis. Pancreas. 2019;48(3):363\u20136.","journal-title":"Pancreas"},{"key":"1501_CR15","doi-asserted-by":"publisher","first-page":"9592831","DOI":"10.1155\/2017\/9592831","volume":"2017","author":"S Lin","year":"2017","unstructured":"Lin S, Hong W, Basharat Z, Wang Q, Pan J, Zhou M. Blood urea nitrogen as a predictor of severe acute pancreatitis based on the revised Atlanta criteria: timing of measurement and cutoff points. Can J Gastroenterol Hepatol. 2017;2017:9592831.","journal-title":"Can J Gastroenterol Hepatol"},{"key":"1501_CR16","doi-asserted-by":"publisher","first-page":"6643595","DOI":"10.1155\/2021\/6643595","volume":"2021","author":"E Pando","year":"2021","unstructured":"Pando E, Alberti P, Mata R, Gomez MJ, Vidal L, Cirera A, et al. Early changes in blood urea nitrogen (BUN) can predict mortality in acute pancreatitis: comparative study between BISAP score, APACHE-II, and other laboratory markers-a prospective observational study. Can J Gastroenterol Hepatol. 2021;2021:6643595.","journal-title":"Can J Gastroenterol Hepatol"},{"key":"1501_CR17","doi-asserted-by":"publisher","first-page":"7785497","DOI":"10.1155\/2022\/7785497","volume":"2022","author":"M Dai","year":"2022","unstructured":"Dai M, Fan Y, Pan P, Tan Y. Blood urea nitrogen as a prognostic marker in severe acute pancreatitis. Dis Markers. 2022;2022:7785497.","journal-title":"Dis Markers"},{"issue":"10","key":"1501_CR18","first-page":"29","volume":"47","author":"MW Saif","year":"2001","unstructured":"Saif MW, Allegra CJ. Hematological complications of acute pancreatitis: a review. Resid Staff Physician. 2001;47(10):29\u201335.","journal-title":"Resid Staff Physician"},{"key":"1501_CR19","doi-asserted-by":"publisher","first-page":"109","DOI":"10.1016\/j.sopen.2024.03.012","volume":"19","author":"A Metri","year":"2024","unstructured":"Metri A, Bush N, Singh VK. Predicting the severity of acute pancreatitis: current approaches and future directions. Surg Open Sci. 2024;19:109\u201317.","journal-title":"Surg Open Sci"},{"issue":"2","key":"1501_CR20","doi-asserted-by":"publisher","first-page":"104","DOI":"10.1159\/000055899","volume":"2","author":"A Brown","year":"2002","unstructured":"Brown A, Baillargeon JD, Hughes MD, Banks PA. Can fluid resuscitation prevent pancreatic necrosis in severe acute pancreatitis? Pancreatology. 2002;2(2):104\u20137.","journal-title":"Pancreatology"},{"issue":"8","key":"1501_CR21","doi-asserted-by":"publisher","first-page":"1216","DOI":"10.1038\/ajg.2016.271","volume":"111","author":"E Koutroumpakis","year":"2016","unstructured":"Koutroumpakis E, Wu BU, Bakker OJ, Dudekula A, Singh VK, Besselink MG, et al. Admission hematocrit and rise in blood urea nitrogen at 24 h outperform other laboratory markers in predicting persistent organ failure and pancreatic necrosis in acute pancreatitis: a post hoc analysis of three large prospective databases. Am J Gastroenterol. 2016;111(8):1216.","journal-title":"Am J Gastroenterol"},{"issue":"3","key":"1501_CR22","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0265758","volume":"17","author":"M Luo","year":"2022","unstructured":"Luo M, Chen Y, Cheng Y, Li N, Qing H. Association between hematocrit and the 30-day mortality of patients with sepsis: a retrospective analysis based on the large-scale clinical database MIMIC-IV. PLoS ONE. 2022;17(3): e0265758.","journal-title":"PLoS ONE"},{"issue":"4","key":"1501_CR23","doi-asserted-by":"publisher","first-page":"809","DOI":"10.1002\/ehf2.12471","volume":"6","author":"J Khoury","year":"2019","unstructured":"Khoury J, Bahouth F, Stabholz Y, Elias A, Mashiach T, Aronson D. Blood urea nitrogen variation upon admission and at discharge in patients with heart failure. ESC Heart Fail. 2019;6(4):809\u201316.","journal-title":"ESC Heart Fail"},{"issue":"12","key":"1501_CR24","doi-asserted-by":"publisher","first-page":"1451","DOI":"10.1016\/j.hpb.2023.08.013","volume":"25","author":"A Dawson","year":"2023","unstructured":"Dawson A, Karunakaran M, Sharma ZD, Ullah S, Barreto SG. Fluid resuscitation in the early management of acute pancreatitis - evidence from a systematic review and meta-analysis. HPB (Oxford). 2023;25(12):1451\u201365.","journal-title":"HPB (Oxford)"},{"issue":"5","key":"1501_CR25","doi-asserted-by":"publisher","DOI":"10.5812\/hepatmon.114638","volume":"21","author":"XC Zhang","year":"2021","unstructured":"Zhang XC, Lu ZH, Yu WL, Hu QY, Fu L, Chen H, et al. Clinical characteristics and early prognostic factors of severe acute pancreatitis. Hepat Mon. 2021;21(5): e114638.","journal-title":"Hepat Mon"},{"key":"1501_CR26","doi-asserted-by":"publisher","first-page":"5142473","DOI":"10.1155\/2022\/5142473","volume":"2022","author":"SS He","year":"2022","unstructured":"He SS, Li D, He QY, Chen XP, Lin YX, Yu YW, et al. Establishment of early multi-indicator prediction models of moderately severe acute pancreatitis and severe acute pancreatitis. Gastroenterol Res Pract. 2022;2022:5142473.","journal-title":"Gastroenterol Res Pract"},{"issue":"2","key":"1501_CR27","doi-asserted-by":"publisher","first-page":"182","DOI":"10.14744\/SEMB.2022.42966","volume":"57","author":"C Ak","year":"2023","unstructured":"Ak C, Kahraman R, Sayar S, Kilic ET, Adali G, Ozdil K. Prediction of prognosis acute pancreatitis with inflammatory markers and patient characteristics compared to the scoring system: real-life data. Sisli Etfal Hastan Tip Bul. 2023;57(2):182\u20138.","journal-title":"Sisli Etfal Hastan Tip Bul"},{"key":"1501_CR28","doi-asserted-by":"publisher","first-page":"3765","DOI":"10.2147\/IJGM.S475186","volume":"17","author":"H Huang","year":"2024","unstructured":"Huang H, Mo J, Jiang G, Lu Z. Evaluating the therapeutic efficiency and efficacy of blood purification for treating severe acute pancreatitis: a single-center data based on propensity score matching. Int J Gen Med. 2024;17:3765\u201377.","journal-title":"Int J Gen Med"},{"issue":"1","key":"1501_CR29","doi-asserted-by":"publisher","first-page":"102","DOI":"10.1136\/gutjnl-2012-302779","volume":"62","author":"PA Banks","year":"2013","unstructured":"Banks PA, Bollen TL, Dervenis C, Gooszen HG, Johnson CD, Sarr MG, et al. Classification of acute pancreatitis\u20132012: revision of the Atlanta classification and definitions by international consensus. Gut. 2013;62(1):102\u201311.","journal-title":"Gut"},{"issue":"2","key":"1501_CR30","doi-asserted-by":"publisher","first-page":"155","DOI":"10.3109\/03009734.2010.547636","volume":"116","author":"PA Banks","year":"2011","unstructured":"Banks PA, Bollen TL, Dervenis C, Gooszen HG, Johnson CD, Sarr MG, et al. Acute renal failure in severe pancreatitis: a population-based study. Ups J Med Sci. 2011;116(2):155\u20139.","journal-title":"Ups J Med Sci"},{"key":"1501_CR31","doi-asserted-by":"publisher","DOI":"10.2196\/51354","volume":"26","author":"M Li","year":"2024","unstructured":"Li M, Han S, Liang F, Hu C, Zhang B, Hou Q, et al. Machine learning for predicting risk and prognosis of acute kidney disease in critically Ill elderly patients during hospitalization: internet-based and interpretable model study. J Med Internet Res. 2024;26: e51354.","journal-title":"J Med Internet Res"},{"issue":"1","key":"1501_CR32","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0296641","volume":"19","author":"H Huang","year":"2024","unstructured":"Huang H, Huang Z, Chen M, Okamoto K. Evaluation of the therapeutic efficiency and efficacy of blood purification in the treatment of severe acute pancreatitis. PLoS ONE. 2024;19(1): e0296641.","journal-title":"PLoS ONE"},{"issue":"6","key":"1501_CR33","first-page":"443","volume":"61","author":"JH Ranson","year":"1974","unstructured":"Ranson JH, Rifkind KM, Roses DF, Fink SD, Eng K, Localio SA. Objective early identification of severe acute pancreatitis. Am J Gastroenterol. 1974;61(6):443\u201351.","journal-title":"Am J Gastroenterol"},{"issue":"7","key":"1501_CR34","doi-asserted-by":"publisher","first-page":"1302","DOI":"10.1016\/j.pan.2020.09.007","volume":"20","author":"FF van den Berg","year":"2020","unstructured":"van den Berg FF, de Bruijn AC, van Santvoort HC, Issa Y, Boermeester MA. Early laboratory biomarkers for severity in acute pancreatitis; A systematic review and meta-analysis. Pancreatology. 2020;20(7):1302\u201311.","journal-title":"Pancreatology"},{"issue":"6","key":"1501_CR35","doi-asserted-by":"publisher","first-page":"787","DOI":"10.3390\/medicina58060787","volume":"58","author":"DW Lee","year":"2022","unstructured":"Lee DW, Cho CM. Predicting severity of acute pancreatitis. Medicina (Kaunas). 2022;58(6):787.","journal-title":"Medicina (Kaunas)"},{"issue":"28","key":"1501_CR36","doi-asserted-by":"publisher","DOI":"10.1097\/MD.0000000000007312","volume":"96","author":"LH Deng","year":"2017","unstructured":"Deng LH, Hu C, Cai WH, Chen WW, Zhang XX, Shi N, et al. Plasma cytokines can help to identify the development of severe acute pancreatitis on admission. Medicine (Baltimore). 2017;96(28): e7312.","journal-title":"Medicine (Baltimore)"},{"issue":"1","key":"1501_CR37","doi-asserted-by":"publisher","first-page":"338","DOI":"10.3390\/ijms21010338","volume":"21","author":"P Silva-Vaz","year":"2020","unstructured":"Silva-Vaz P, Abrantes AM, Castelo-Branco M, Gouveia A, Botelho MF, Tralh\u00e3o JG. Multifactorial scores and biomarkers of prognosis of acute pancreatitis: applications to research and practice. Int J Mol Sci. 2020;21(1):338.","journal-title":"Int J Mol Sci"},{"issue":"7","key":"1501_CR38","doi-asserted-by":"publisher","first-page":"669","DOI":"10.1001\/archinternmed.2011.126","volume":"171","author":"BU Wu","year":"2011","unstructured":"Wu BU, Bakker OJ, Papachristou GI, Besselink MG, Repas K, van Santvoort HC, et al. Blood urea nitrogen in the early assessment of acute pancreatitis: an international validation study. Arch Intern Med. 2011;171(7):669\u201376.","journal-title":"Arch Intern Med"},{"issue":"7","key":"1501_CR39","doi-asserted-by":"publisher","first-page":"482","DOI":"10.7326\/M16-0650","volume":"165","author":"MY Di","year":"2016","unstructured":"Di MY, Liu H, Yang ZY, Bonis PA, Tang JL, Lau J. Prediction models of mortality in acute pancreatitis in adults: a systematic review. Ann Intern Med. 2016;165(7):482\u201390.","journal-title":"Ann Intern Med"},{"issue":"19","key":"1501_CR40","doi-asserted-by":"publisher","first-page":"5565","DOI":"10.3390\/jcm11195565","volume":"11","author":"J Walkowska","year":"2022","unstructured":"Walkowska J, Zielinska N, Karauda P, Tubbs RS, Kurtys K, Olewnik \u0141. The pancreas and known factors of acute pancreatitis. J Clin Med. 2022;11(19):5565.","journal-title":"J Clin Med"},{"key":"1501_CR41","doi-asserted-by":"publisher","first-page":"27","DOI":"10.1186\/s13017-019-0247-0","volume":"14","author":"A Lepp\u00e4niemi","year":"2019","unstructured":"Lepp\u00e4niemi A, Tolonen M, Tarasconi A, Segovia-Lohse H, Gamberini E, Kirkpatrick AW, et al. 2019 WSES guidelines for the management of severe acute pancreatitis. World J Emerg Surg. 2019;14:27.","journal-title":"World J Emerg Surg"},{"key":"1501_CR42","doi-asserted-by":"publisher","first-page":"8201096","DOI":"10.1155\/2019\/8201096","volume":"2019","author":"J Wan","year":"2019","unstructured":"Wan J, Shu W, He W, Zhu Y, Zhu Y, Zeng H, et al. Serum creatinine level and APACHE-II score within 24 h of admission are effective for predicting persistent organ failure in acute pancreatitis. Gastroenterol Res Pract. 2019;2019:8201096.","journal-title":"Gastroenterol Res Pract"},{"issue":"7","key":"1501_CR43","doi-asserted-by":"publisher","first-page":"523","DOI":"10.7326\/M16-1581","volume":"165","author":"CE Forsmark","year":"2016","unstructured":"Forsmark CE, Yadav D. Predicting the prognosis of acute pancreatitis. Ann Intern Med. 2016;165(7):523\u20134.","journal-title":"Ann Intern Med"},{"issue":"12","key":"1501_CR44","first-page":"1","volume":"14","author":"TG Chitrambalam","year":"2020","unstructured":"Chitrambalam TG, Rajasekhar S, Sundaraj J, Panicker KM, Paladugu R. A longitudinal study on comparison of haematocrit, glasgow score and computed tomography abdomen as prognostic markers in assessment of severity in acute pancreatitis. J Clin Diagn Res. 2020;14(12):1.","journal-title":"J Clin Diagn Res"},{"issue":"8","key":"1501_CR45","doi-asserted-by":"publisher","first-page":"479","DOI":"10.1038\/s41575-019-0158-2","volume":"16","author":"PJ Lee","year":"2019","unstructured":"Lee PJ, Papachristou GI. New insights into acute pancreatitis. Nat Rev Gastroenterol Hepatol. 2019;16(8):479\u201396.","journal-title":"Nat Rev Gastroenterol Hepatol"},{"issue":"4","key":"1501_CR46","doi-asserted-by":"publisher","first-page":"1096","DOI":"10.1053\/j.gastro.2018.01.032","volume":"154","author":"SD Crockett","year":"2018","unstructured":"Crockett SD, Wani S, Gardner TB, Falck-Ytter Y, Barkun AN. American gastroenterological association institute clinical guidelines committee. American gastroenterological association institute guideline on initial management of acute pancreatitis. Gastroenterology. 2018;154(4):1096\u2013101.","journal-title":"Gastroenterology"},{"issue":"3","key":"1501_CR47","doi-asserted-by":"publisher","first-page":"292","DOI":"10.1136\/flgastro-2018-101102","volume":"10","author":"G Goodchild","year":"2019","unstructured":"Goodchild G, Chouhan M, Johnson GJ. Practical guide to the management of acute pancreatitis. Frontline Gastroenterol. 2019;10(3):292\u20139.","journal-title":"Frontline Gastroenterol"},{"issue":"7","key":"1501_CR48","doi-asserted-by":"publisher","first-page":"2081","DOI":"10.1111\/j.1572-0241.2001.03966.x","volume":"96","author":"PG Lankisch","year":"2001","unstructured":"Lankisch PG, Mahlke R, Blum T, Bruns A, Bruns D, Maisonneuve P, et al. Hemoconcentration: an early marker of severe and\/or necrotizing pancreatitis? A critical appraisal. Am J Gastroenterol. 2001;96(7):2081\u20135.","journal-title":"Am J Gastroenterol"},{"issue":"4","key":"1501_CR49","doi-asserted-by":"publisher","first-page":"295","DOI":"10.1080\/13651820701329225","volume":"9","author":"G Pupelis","year":"2007","unstructured":"Pupelis G, Plaudis H, Grigane A, Zeiza K, Purmalis G. Continuous veno-venous haemofiltration in the treatment of severe acute pancreatitis: 6-year experience. HPB (Oxford). 2007;9(4):295\u2013301.","journal-title":"HPB (Oxford)"}],"container-title":["Journal of Artificial Organs"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s10047-025-01501-2.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s10047-025-01501-2\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s10047-025-01501-2.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,9,6]],"date-time":"2025-09-06T15:28:01Z","timestamp":1757172481000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s10047-025-01501-2"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,4,25]]},"references-count":49,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2025,9]]}},"alternative-id":["1501"],"URL":"https:\/\/doi.org\/10.1007\/s10047-025-01501-2","relation":{},"ISSN":["1434-7229","1619-0904"],"issn-type":[{"value":"1434-7229","type":"print"},{"value":"1619-0904","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,4,25]]},"assertion":[{"value":"9 January 2025","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"30 March 2025","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"25 April 2025","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"All the authors declare that they have no competing interests.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of interest"}},{"value":"This study was approved by the Ethics Committee of the People's Hospital of Guangxi Zhuang Autonomous Region (approval number: KY-KJT-2023-184), and all patients provided written informed consent to participate in this study.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethical approval"}}]}}