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It is unclear if sensitization poses additional risks in patients bridged to transplantation with venovenous extracorporeal membrane oxygenation (VV-ECMO). This study compares outcomes between cPRA-positive and -negative patients bridged with VV-ECMO.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>Among 411 transplant recipients from an institutional lung transplantation database (January 2018\u2013March 2025), 52 patients were bridged with VV-ECMO. Of these, 14 were cPRA-positive and 38 were cPRA-negative. Univariate and multivariate analyses evaluated early post-transplant complications and survival outcomes in cPRA-positive and -negative groups.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Rates of post-transplant complications such as primary graft dysfunction (PGD) in any grade (85.7% cPRA-positive vs. 76.4% cPRA-negative,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.48), PGD grade 3 (35.7% vs. 50.0%,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.53), acute kidney injury (AKI) (64.3% vs. 68.4%,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20091.00), dialysis requirement (21.4% vs. 34.2%,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.51), deep vein thrombosis (DVT) (71.4% vs. 55.3%,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.35), and pulmonary embolism (PE) (7.1% vs. 18.4%,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.42) were similar. 1-year survival rate (85.1% vs. 82.9%) and overall survival (\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.81) were not significantly different.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>Post-transplant outcomes and survival were similar between cPRA-positive and -negative groups, suggesting that PRA status in VV-ECMO bridged lung transplant recipients is not associated with worse outcomes. VV-ECMO may remain a viable bridge to lung transplantation, even in sensitized patients.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1007\/s10047-025-01539-2","type":"journal-article","created":{"date-parts":[[2025,11,14]],"date-time":"2025-11-14T00:18:38Z","timestamp":1763079518000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":6,"title":["Outcomes of venovenous-extracorporeal membrane oxygenation bridging in lung transplant recipients with panel reactive antibody positivity"],"prefix":"10.1007","volume":"29","author":[{"given":"Austin","family":"Chang","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yudai","family":"Miyashita","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Benjamin Louis","family":"Thomae","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Amanda","family":"Kamar","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Taisuke","family":"Kaiho","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3536-4675","authenticated-orcid":false,"given":"Chitaru","family":"Kurihara","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2025,11,13]]},"reference":[{"key":"1539_CR1","doi-asserted-by":"publisher","DOI":"10.1080\/17476348.2024.2447513","author":"Y Miyashita","year":"2024","unstructured":"Miyashita Y, Kaiho T, Kurihara C. 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