{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,10]],"date-time":"2026-09-10T16:11:57Z","timestamp":1789056717336,"version":"build-2803163510"},"reference-count":15,"publisher":"Springer Science and Business Media LLC","issue":"3","license":[{"start":{"date-parts":[[2026,7,30]],"date-time":"2026-07-30T00:00:00Z","timestamp":1785369600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"},{"start":{"date-parts":[[2026,7,30]],"date-time":"2026-07-30T00:00:00Z","timestamp":1785369600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["J Artif Organs"],"published-print":{"date-parts":[[2026,9]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>\n                    The novel lab-scale hollow fiber membrane module was fabricated to determine the apparent sieving coefficient (\n                    <jats:inline-formula>\n                      <jats:tex-math>$${SC}_{obs}$$<\/jats:tex-math>\n                    <\/jats:inline-formula>\n                    ) of commercial hemodiafiltration membranes, MFX-SW eco (polyethersulfone, Sample A) and NVF-P (polysulfone, Sample B), using the aqueous solution of dextran with a broader molecular weight distribution. All the molecular weight cut-off curves plotted as\n                    <jats:inline-formula>\n                      <jats:tex-math>$${SC}_{obs}$$<\/jats:tex-math>\n                    <\/jats:inline-formula>\n                    versus filtration flow rate (\n                    <jats:italic>Q<\/jats:italic>\n                    <jats:sub>\n                      <jats:italic>F<\/jats:italic>\n                    <\/jats:sub>\n                    ) exhibited smooth profiles without intersecting each other, showing distinct variations depending on\n                    <jats:italic>Q<\/jats:italic>\n                    <jats:sub>\n                      <jats:italic>F<\/jats:italic>\n                    <\/jats:sub>\n                    across a wide range of molecular weights. Field emission scanning electron microscopy (FE-SEM) observations revealed that the equivalent pore diameters of samples A and B were nearly identical at 23.0\u2009\u00b1\u200915.5\u00a0nm and 23.3\u2009\u00b1\u200915.5\u00a0nm, respectively. Although the surface porosity of sample A (14.5\u2009\u00b1\u20093.9%) was higher than that of sample B (10.2\u2009\u00b1\u20093.2%), the difference was not statistically significant. These numerical data were in excellent agreement with the qualitative morphological findings obtained from the FE-SEM images. Furthermore, it is suggested that the subtle structural differences between the two membranes are also reflected in the relationship between the real sieving coefficients (\n                    <jats:inline-formula>\n                      <jats:tex-math>$${SC}_{real}$$<\/jats:tex-math>\n                    <\/jats:inline-formula>\n                    ) calculated by using\n                    <jats:inline-formula>\n                      <jats:tex-math>$${SC}_{obs}$$<\/jats:tex-math>\n                    <\/jats:inline-formula>\n                    and the equivalent pore diameters. Since the lab-scale modules are fabricated relatively easily by hand, this methodology is extremely valuable to rigorously define membrane performance.\n                  <\/jats:p>","DOI":"10.1007\/s10047-026-01577-4","type":"journal-article","created":{"date-parts":[[2026,7,30]],"date-time":"2026-07-30T16:22:22Z","timestamp":1785428542000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Correlation between real sieving coefficient determined using novel lab-scale module and pore structure of hemodiafiltration membranes"],"prefix":"10.1007","volume":"29","author":[{"given":"Mizuki","family":"Ichikawa","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3776-6662","authenticated-orcid":false,"given":"Makoto","family":"Fukuda","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Takuma","family":"Morikawa","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kousei","family":"Takeuchi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kiyotaka","family":"Sakai","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2026,7,30]]},"reference":[{"key":"1577_CR1","doi-asserted-by":"publisher","first-page":"83","DOI":"10.1007\/s10047-023-01431-x","volume":"27","author":"M Fukuda","year":"2024","unstructured":"Fukuda M, Sakai K. 3D porous structure imaging of membranes for medical devices using scanning probe microscopy and electron microscopy\u2013from membrane science points of view. 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Therefore, ethical approval was not required.","order":2,"name":"Ethics","label":"Ethical approval","group":{"name":"EthicsHeading","label":"Declarations"}}],"article-number":"49"}}