{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,6]],"date-time":"2026-10-06T20:19:01Z","timestamp":1791317941933,"version":"4.3.1"},"reference-count":54,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2007,10,17]],"date-time":"2007-10-17T00:00:00Z","timestamp":1192579200000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Neurogenetics"],"published-print":{"date-parts":[[2008,2]]},"DOI":"10.1007\/s10048-007-0103-3","type":"journal-article","created":{"date-parts":[[2007,10,16]],"date-time":"2007-10-16T11:58:24Z","timestamp":1192535904000},"page":"51-60","source":"Crossref","is-referenced-by-count":23,"title":["Age-at-onset linkage analysis in Caribbean Hispanics with familial late-onset Alzheimer\u2019s disease"],"prefix":"10.1007","volume":"9","author":[{"given":"Joseph H.","family":"Lee","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sandra","family":"Barral","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rong","family":"Cheng","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Inara","family":"Chacon","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vincent","family":"Santana","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jennifer","family":"Williamson","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rafael","family":"Lantigua","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Martin","family":"Medrano","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ivonne Z.","family":"Jimenez-Velazquez","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yaakov","family":"Stern","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Benjamin","family":"Tycko","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ekaterina","family":"Rogaeva","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yosuke","family":"Wakutani","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Toshitaka","family":"Kawarai","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Peter","family":"St George-Hyslop","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Richard","family":"Mayeux","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2007,10,17]]},"reference":[{"key":"103_CR1","doi-asserted-by":"crossref","first-page":"1356","DOI":"10.1056\/NEJM2003ra020003","volume":"348","author":"RL Nussbaum","year":"2003","unstructured":"Nussbaum RL, Ellis CE (2003) Alzheimer\u2019s disease and Parkinson\u2019s disease. N Engl J Med 348:1356\u20131364","journal-title":"N Engl J Med"},{"key":"103_CR2","doi-asserted-by":"crossref","first-page":"119","DOI":"10.1016\/j.crvi.2004.10.013","volume":"328","author":"PH St George-Hyslop","year":"2005","unstructured":"St George-Hyslop PH, Petit A (2005) Molecular biology and genetics of Alzheimer\u2019s disease. C R Biol 328:119\u2013130","journal-title":"C R Biol"},{"key":"103_CR3","doi-asserted-by":"crossref","first-page":"545","DOI":"10.1016\/j.cell.2005.02.008","volume":"120","author":"RE Tanzi","year":"2005","unstructured":"Tanzi RE, Bertram L (2005) Twenty years of the Alzheimer\u2019s disease amyloid hypothesis: a genetic perspective. Cell 120:545\u2013555","journal-title":"Cell"},{"key":"103_CR4","doi-asserted-by":"crossref","first-page":"125","DOI":"10.1007\/s11920-004-0052-6","volume":"6","author":"P Pastor","year":"2004","unstructured":"Pastor P, Goate AM (2004) Molecular genetics of Alzheimer\u2019s disease. Curr Psychiatry Rep 6:125\u2013133","journal-title":"Curr Psychiatry Rep"},{"key":"103_CR5","first-page":"2037","volume-title":"Genetic dissection of complex traits, vol 265","author":"ES Lander","year":"1994","unstructured":"Lander ES, Schork NJ (1994) Genetic dissection of complex traits, vol 265. Science, New York, NY, pp 2037\u20132048"},{"key":"103_CR6","doi-asserted-by":"crossref","first-page":"381","DOI":"10.1046\/j.1529-8817.2004.00110.x","volume":"68","author":"MI Kamboh","year":"2004","unstructured":"Kamboh MI (2004) Molecular genetics of late-onset Alzheimer\u2019s disease. Ann Hum Genet 68:381\u2013404","journal-title":"Ann Hum Genet"},{"key":"103_CR7","doi-asserted-by":"crossref","first-page":"139","DOI":"10.1212\/WNL.48.1.139","volume":"48","author":"D Blacker","year":"1997","unstructured":"Blacker D, Haines JL, Rodes L, Terwedow H, Go RC, Harrell LE et al (1997) ApoE-4 and age at onset of Alzheimer\u2019s disease: the NIMH genetics initiative. Neurology 48:139\u2013147","journal-title":"Neurology"},{"key":"103_CR8","doi-asserted-by":"crossref","first-page":"40","DOI":"10.1097\/00002093-199803000-00006","volume":"12","author":"JC Breitner","year":"1998","unstructured":"Breitner JC, Jarvik GP, Plassman BL, Saunders AM, Welsh KA (1998) Risk of Alzheimer disease with the epsilon4 allele for apolipoprotein E in a population-based study of men aged 62\u201373\u00a0years. Alzheimer Dis Assoc Disord 12:40\u201344","journal-title":"Alzheimer Dis Assoc Disord"},{"key":"103_CR9","first-page":"921","volume-title":"Gene dose of apolipoprotein E type 4 allele and the risk of Alzheimer\u2019s disease in late onset families, vol 261","author":"EH Corder","year":"1993","unstructured":"Corder EH, Saunders AM, Strittmatter WJ, Schmechel DE, Gaskell PC, Small GW et al (1993) Gene dose of apolipoprotein E type 4 allele and the risk of Alzheimer\u2019s disease in late onset families, vol 261. Science, New York, NY, pp 921\u2013923"},{"key":"103_CR10","doi-asserted-by":"crossref","first-page":"317","DOI":"10.1017\/S104161020400033X","volume":"16","author":"DG Harwood","year":"2004","unstructured":"Harwood DG, Barker WW, Ownby RL, St George-Hyslop P, Mullan M, Duara R (2004) Apolipoprotein E polymorphism and age of onset for Alzheimer\u2019s disease in a bi-ethnic sample. Int Psychogeriatr 16:317\u2013326","journal-title":"Int Psychogeriatr"},{"key":"103_CR11","doi-asserted-by":"crossref","first-page":"201","DOI":"10.1007\/s10048-004-0189-9","volume":"5","author":"KK Nicodemus","year":"2004","unstructured":"Nicodemus KK, Stenger JE, Schmechel DE, Welsh-Bohmer KA, Saunders AM, Roses AD et al (2004) Comprehensive association analysis of APOE regulatory region polymorphisms in Alzheimer disease. Neurogenetics 5:201\u2013208","journal-title":"Neurogenetics"},{"key":"103_CR12","doi-asserted-by":"crossref","first-page":"14","DOI":"10.1002\/ajmg.b.30087","volume":"132","author":"EM Wijsman","year":"2005","unstructured":"Wijsman EM, Daw EW, Yu X, Steinbart EJ, Nochlin D, Bird TD et al (2005) APOE and other loci affect age-at-onset in Alzheimer\u2019s disease families with PS2 mutation. Am J Med Genet B Neuropsychiatr Genet 132:14\u201320","journal-title":"Am J Med Genet B Neuropsychiatr Genet"},{"key":"103_CR13","doi-asserted-by":"crossref","first-page":"196","DOI":"10.1086\/302710","volume":"66","author":"EW Daw","year":"2000","unstructured":"Daw EW, Payami H, Nemens EJ, Nochlin D, Bird TD, Schellenberg GD et al (2000) The number of trait loci in late-onset Alzheimer disease. Am J Hum Genet 66:196\u2013204","journal-title":"Am J Hum Genet"},{"key":"103_CR14","doi-asserted-by":"crossref","first-page":"24","DOI":"10.1002\/ajmg.b.30114","volume":"135","author":"P Holmans","year":"2005","unstructured":"Holmans P, Hamshere M, Hollingworth P, Rice F, Tunstall N, Jones S et al (2005) Genome screen for loci influencing age at onset and rate of decline in late onset Alzheimer\u2019s disease. Am J Med Genet B Neuropsychiatr Genet 135:24\u201332","journal-title":"Am J Med Genet B Neuropsychiatr Genet"},{"key":"103_CR15","doi-asserted-by":"crossref","first-page":"985","DOI":"10.1086\/339815","volume":"70","author":"YJ Li","year":"2002","unstructured":"Li YJ, Scott WK, Hedges DJ, Zhang F, Gaskell PC, Nance MA et al (2002) Age at onset in two common neurodegenerative diseases is genetically controlled. Am J Hum Genet 70:985\u2013993","journal-title":"Am J Hum Genet"},{"key":"103_CR16","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/0304-3940(94)11100-W","volume":"183","author":"B Nacmias","year":"1995","unstructured":"Nacmias B, Latorraca S, Piersanti P, Forleo P, Piacentini S, Bracco L et al (1995) ApoE genotype and familial Alzheimer\u2019s disease: a possible influence on age of onset in APP717 Val\u2013>Ile mutated families. Neurosci Lett 183:1\u20133","journal-title":"Neurosci Lett"},{"key":"103_CR17","doi-asserted-by":"crossref","first-page":"154","DOI":"10.1086\/341034","volume":"71","author":"JM Olson","year":"2002","unstructured":"Olson JM, Goddard KA, Dudek DM (2002) A second locus for very-late-onset Alzheimer disease: a genome scan reveals linkage to 20\u00a0p and epistasis between 20\u00a0p and the amyloid precursor protein region. Am J Hum Genet 71:154\u2013161","journal-title":"Am J Hum Genet"},{"key":"103_CR18","doi-asserted-by":"crossref","first-page":"643","DOI":"10.1086\/491749","volume":"77","author":"R Rademakers","year":"2005","unstructured":"Rademakers R, Cruts M, Sleegers K, Dermaut B, Theuns J, Aulchenko Y et al (2005) Linkage and association studies identify a novel locus for Alzheimer disease at 7q36 in a Dutch population-based sample. Am J Hum Genet 77:643\u2013652","journal-title":"Am J Hum Genet"},{"key":"103_CR19","doi-asserted-by":"crossref","first-page":"67","DOI":"10.1016\/S0304-3940(99)00417-6","volume":"269","author":"F Wavrant-De Vrieze","year":"1999","unstructured":"Wavrant-De Vrieze F, Crook R, Holmans P, Kehoe P, Owen MJ, Williams J et al (1999) Genetic variability at the amyloid-beta precursor protein locus may contribute to the risk of late-onset Alzheimer\u2019s disease. Neurosci Lett 269:67\u201370","journal-title":"Neurosci Lett"},{"key":"103_CR20","doi-asserted-by":"crossref","first-page":"398","DOI":"10.1086\/423393","volume":"75","author":"EM Wijsman","year":"2004","unstructured":"Wijsman EM, Daw EW, Yu CE, Payami H, Steinbart EJ, Nochlin D et al (2004) Evidence for a novel late-onset Alzheimer disease locus on chromosome 19p13.2. Am J Hum Genet 75:398\u2013409","journal-title":"Am J Hum Genet"},{"key":"103_CR21","doi-asserted-by":"crossref","first-page":"1591","DOI":"10.1001\/archneur.63.11.1591","volume":"63","author":"JH Lee","year":"2006","unstructured":"Lee JH, Cheng R, Santana V, Williamson J, Lantigua R, Medrano M et al (2006) Expanded genomewide scan implicates a novel locus at 3q28 among Caribbean hispanics with familial Alzheimer disease. Arch Neurol 63:1591\u20131598","journal-title":"Arch Neurol"},{"key":"103_CR22","doi-asserted-by":"crossref","first-page":"1042","DOI":"10.1038\/sj.mp.4001538","volume":"9","author":"JH Lee","year":"2004","unstructured":"Lee JH, Mayeux R, Mayo D, Mo J, Santana V, Williamson J et al (2004) Fine mapping of 10q and 18q for familial Alzheimer\u2019s disease in Caribbean Hispanics. Mol Psychiatry 9:1042\u20131051","journal-title":"Mol Psychiatry"},{"key":"103_CR23","doi-asserted-by":"crossref","first-page":"939","DOI":"10.1212\/WNL.34.7.939","volume":"34","author":"G McKhann","year":"1984","unstructured":"McKhann G, Drachman D, Folstein M, Katzman R, Price D, Stadlan EM (1984) Clinical diagnosis of Alzheimer\u2019s disease: report of the NINCDS-ADRDA Work Group under the auspices of Department of Health and Human Services Task Force on Alzheimer\u2019s Disease. Neurology 34:939\u2013944","journal-title":"Neurology"},{"key":"103_CR24","doi-asserted-by":"crossref","first-page":"566","DOI":"10.1192\/bjp.140.6.566","volume":"140","author":"CP Hughes","year":"1982","unstructured":"Hughes CP, Berg L, Danziger WL, Coben LA, Martin RL (1982) A new clinical scale for the staging of dementia. Br J Psychiatry 140:566\u2013572","journal-title":"Br J Psychiatry"},{"key":"103_CR25","doi-asserted-by":"crossref","first-page":"461","DOI":"10.1001\/archneur.1992.00530290043010","volume":"49","author":"J Pittman","year":"1992","unstructured":"Pittman J, Andrews H, Tatemichi T, Link B, Struening E, Stern Y et al (1992) Diagnosis of dementia in a heterogeneous population. A comparison of paradigm-based diagnosis and physician\u2019s diagnosis. Arch Neurol 49:461\u2013467","journal-title":"Arch Neurol"},{"key":"103_CR26","doi-asserted-by":"crossref","first-page":"453","DOI":"10.1001\/archneur.1992.00530290035009","volume":"49","author":"Y Stern","year":"1992","unstructured":"Stern Y, Andrews H, Pittman J, Sano M, Tatemichi T, Lantigua R et al (1992) Diagnosis of dementia in a heterogeneous population. Development of a neuropsychological paradigm-based diagnosis of dementia and quantified correction for the effects of education. Arch Neurol 49:453\u2013460","journal-title":"Arch Neurol"},{"key":"103_CR27","doi-asserted-by":"crossref","first-page":"311","DOI":"10.1017\/S1355617798003117","volume":"4","author":"L Stricks","year":"1998","unstructured":"Stricks L, Pittman J, Jacobs DM, Sano M, Stern Y (1998) Normative data for a brief neuropsychological battery administered to English- and Spanish-speaking community-dwelling elders. J Int Neuropsychol Soc 4:311\u2013318","journal-title":"J Int Neuropsychol Soc"},{"key":"103_CR28","doi-asserted-by":"crossref","first-page":"1109","DOI":"10.1212\/WNL.54.5.1109","volume":"54","author":"M Ganguli","year":"2000","unstructured":"Ganguli M, Dodge HH, Chen P, Belle S, DeKosky ST (2000) Ten-year incidence of dementia in a rural elderly US community population: the MoVIES Project. Neurology 54:1109\u20131116","journal-title":"Neurology"},{"key":"103_CR29","doi-asserted-by":"crossref","first-page":"545","DOI":"10.1016\/S0022-2275(20)43176-1","volume":"31","author":"JE Hixson","year":"1990","unstructured":"Hixson JE, Vernier DT (1990) Restriction isotyping of human apolipoprotein E by gene amplification and cleavage with HhaI. J Lipid Res 31:545\u2013548","journal-title":"J Lipid Res"},{"key":"103_CR30","doi-asserted-by":"crossref","first-page":"254","DOI":"10.1002\/ana.410370217","volume":"37","author":"G Maestre","year":"1995","unstructured":"Maestre G, Ottman R, Stern Y, Gurland B, Chun M, Tang MX et al (1995) Apolipoprotein E and Alzheimer\u2019s disease: ethnic variation in genotypic risks. Ann Neurol 37:254\u2013259","journal-title":"Ann Neurol"},{"key":"103_CR31","doi-asserted-by":"crossref","first-page":"2257","DOI":"10.1001\/jama.286.18.2257","volume":"286","author":"ES Athan","year":"2001","unstructured":"Athan ES, Williamson J, Ciappa A, Santana V, Romas SN, Lee JH et al (2001) A founder mutation in presenilin 1 causing early-onset Alzheimer disease in unrelated Caribbean Hispanic families. JAMA 286:2257\u20132263","journal-title":"JAMA"},{"key":"103_CR32","doi-asserted-by":"crossref","first-page":"51","DOI":"10.1146\/annurev.publhealth.18.1.51","volume":"18","author":"JS Preisser","year":"1997","unstructured":"Preisser JS, Koch GG (1997) Categorical data analysis in public health. Annu Rev Public Health 18:51\u201382","journal-title":"Annu Rev Public Health"},{"key":"103_CR33","doi-asserted-by":"crossref","first-page":"1825","DOI":"10.1002\/sim.4780111406","volume":"11","author":"SL Zeger","year":"1992","unstructured":"Zeger SL, Liang KY (1992) An overview of methods for the analysis of longitudinal data. Stat Med 11:1825\u20131839","journal-title":"Stat Med"},{"key":"103_CR34","first-page":"535","volume":"54","author":"CI Amos","year":"1994","unstructured":"Amos CI (1994) Robust variance-components approach for assessing genetic linkage in pedigrees. Am J Hum Genet 54:535\u2013543","journal-title":"Am J Hum Genet"},{"key":"103_CR35","doi-asserted-by":"crossref","first-page":"1198","DOI":"10.1086\/301844","volume":"62","author":"L Almasy","year":"1998","unstructured":"Almasy L, Blangero J (1998) Multipoint quantitative-trait linkage analysis in general pedigrees. Am J Hum Genet 62:1198\u20131211","journal-title":"Am J Hum Genet"},{"issue":"Suppl 1","key":"103_CR36","doi-asserted-by":"crossref","first-page":"S109","DOI":"10.1002\/gepi.1370170719","volume":"17","author":"AG Comuzzie","year":"1999","unstructured":"Comuzzie AG, Williams JT (1999) Correcting for ascertainment bias in the COGA data set. Genet Epidemiol 17(Suppl 1):S109\u2013S114","journal-title":"Genet Epidemiol"},{"key":"103_CR37","doi-asserted-by":"crossref","first-page":"963","DOI":"10.1093\/genetics\/138.3.963","volume":"138","author":"GA Churchill","year":"1994","unstructured":"Churchill GA, Doerge RW (1994) Empirical threshold values for quantitative trait mapping. Genetics 138:963\u2013971","journal-title":"Genetics"},{"key":"103_CR38","doi-asserted-by":"crossref","first-page":"285","DOI":"10.1093\/genetics\/142.1.285","volume":"142","author":"RW Doerge","year":"1996","unstructured":"Doerge RW, Churchill GA (1996) Permutation tests for multiple loci affecting a quantitative character. Genetics 142:285\u2013294","journal-title":"Genetics"},{"key":"103_CR39","doi-asserted-by":"crossref","first-page":"301","DOI":"10.1038\/sj.ejhg.5200625","volume":"9","author":"S Horvath","year":"2001","unstructured":"Horvath S, Xu X, Laird NM (2001) The family based association test method: strategies for studying general genotype\u2013phenotype associations. Eur J Hum Genet 9:301\u2013306","journal-title":"Eur J Hum Genet"},{"key":"103_CR40","doi-asserted-by":"crossref","first-page":"211","DOI":"10.1159\/000022918","volume":"50","author":"D Rabinowitz","year":"2000","unstructured":"Rabinowitz D, Laird N (2000) A unified approach to adjusting association tests for population admixture with arbitrary pedigree structure and arbitrary missing marker information. Hum Hered 50:211\u2013223","journal-title":"Hum Hered"},{"key":"103_CR41","doi-asserted-by":"crossref","first-page":"3259","DOI":"10.1093\/hmg\/ddg357","volume":"12","author":"YJ Li","year":"2003","unstructured":"Li YJ, Oliveira SA, Xu P, Martin ER, Stenger JE, Scherzer CR et al (2003) Glutathione S-transferase omega-1 modifies age-at-onset of Alzheimer disease and Parkinson disease. Hum Mol Genet 12:3259\u20133267","journal-title":"Hum Mol Genet"},{"key":"103_CR42","doi-asserted-by":"crossref","first-page":"9","DOI":"10.1002\/ajmg.b.30074","volume":"132","author":"D Avramopoulos","year":"2005","unstructured":"Avramopoulos D, Fallin MD, Bassett SS (2005) Linkage to chromosome 14q in Alzheimer\u2019s disease (AD) patients without psychotic symptoms. Am J Med Genet B Neuropsychiatr Genet 132:9\u201313","journal-title":"Am J Med Genet B Neuropsychiatr Genet"},{"key":"103_CR43","doi-asserted-by":"crossref","first-page":"1435","DOI":"10.1016\/j.neurobiolaging.2005.07.015","volume":"27","author":"MI Kamboh","year":"2006","unstructured":"Kamboh MI, Minster RL, Kenney M, Ozturk A, Desai PP, Kammerer CM et al (2006) Alpha-1-antichymotrypsin (ACT or SERPINA3) polymorphism may affect age-at-onset and disease duration of Alzheimer\u2019s disease. Neurobiol Aging 27:1435\u20131439","journal-title":"Neurobiol Aging"},{"key":"103_CR44","doi-asserted-by":"crossref","first-page":"847","DOI":"10.1038\/35015718","volume":"405","author":"NJ Risch","year":"2000","unstructured":"Risch NJ (2000) Searching for genetic determinants in the new millennium. Nature 405:847\u2013856","journal-title":"Nature"},{"key":"103_CR45","doi-asserted-by":"crossref","first-page":"156","DOI":"10.1192\/bjp.176.2.156","volume":"176","author":"N Tunstall","year":"2000","unstructured":"Tunstall N, Owen MJ, Williams J, Rice F, Carty S, Lillystone S et al (2000) Familial influence on variation in age of onset and behavioural phenotype in Alzheimer\u2019s disease. Br J Psychiatry 176:156\u2013159","journal-title":"Br J Psychiatry"},{"key":"103_CR46","doi-asserted-by":"crossref","first-page":"613","DOI":"10.4088\/JCP.v68n0419","volume":"68","author":"KD Coon","year":"2007","unstructured":"Coon KD, Myers AJ, Craig DW, Webster JA, Pearson JV, Lince DH et al (2007) A high-density whole-genome association study reveals that APOE is the major susceptibility gene for sporadic late-onset Alzheimer\u2019s disease. J Clin Psychiatry 68:613\u2013618","journal-title":"J Clin Psychiatry"},{"key":"103_CR47","doi-asserted-by":"crossref","first-page":"121","DOI":"10.1007\/s10048-004-0174-3","volume":"5","author":"KA Goddard","year":"2004","unstructured":"Goddard KA, Olson JM, Payami H, van der Voet M, Kuivaniemi H, Tromp G (2004) Evidence of linkage and association on chromosome 20 for late-onset Alzheimer disease. Neurogenetics 5:121\u2013128","journal-title":"Neurogenetics"},{"key":"103_CR48","doi-asserted-by":"crossref","first-page":"2255","DOI":"10.1212\/01.WNL.0000147294.29309.47","volume":"63","author":"H Kolsch","year":"2004","unstructured":"Kolsch H, Linnebank M, Lutjohann D, Jessen F, Wullner U, Harbrecht U et al (2004) Polymorphisms in glutathione S-transferase omega-1 and AD, vascular dementia, and stroke. Neurology 63:2255\u20132260","journal-title":"Neurology"},{"key":"103_CR49","doi-asserted-by":"crossref","first-page":"140","DOI":"10.1016\/j.neulet.2004.06.076","volume":"368","author":"M Nishimura","year":"2004","unstructured":"Nishimura M, Sakamoto T, Kaji R, Kawakami H (2004) Influence of polymorphisms in the genes for cytokines and glutathione S-transferase omega on sporadic Alzheimer\u2019s disease. Neurosci Lett 368:140\u2013143","journal-title":"Neurosci Lett"},{"key":"103_CR50","doi-asserted-by":"crossref","first-page":"1161","DOI":"10.1016\/j.neurobiolaging.2004.11.001","volume":"26","author":"A Ozturk","year":"2005","unstructured":"Ozturk A, Desai PP, Minster RL, Dekosky ST, Kamboh MI (2005) Three SNPs in the GSTO1, GSTO2 and PRSS11 genes on chromosome 10 are not associated with age-at-onset of Alzheimer\u2019s disease. Neurobiol Aging 26:1161\u20131165","journal-title":"Neurobiol Aging"},{"key":"103_CR51","doi-asserted-by":"crossref","first-page":"60","DOI":"10.1016\/j.bbapap.2005.02.013","volume":"1751","author":"M Higuchi","year":"2005","unstructured":"Higuchi M, Iwata N, Saido TC (2005) Understanding molecular mechanisms of proteolysis in Alzheimer\u2019s disease: progress toward therapeutic interventions. Biochim Biophys Acta 1751:60\u201367","journal-title":"Biochim Biophys Acta"},{"key":"103_CR52","doi-asserted-by":"crossref","first-page":"15229","DOI":"10.1074\/jbc.M500939200","volume":"280","author":"M Higuchi","year":"2005","unstructured":"Higuchi M, Tomioka M, Takano J, Shirotani K, Iwata N, Masumoto H et al (2005) Distinct mechanistic roles of calpain and caspase activation in neurodegeneration as revealed in mice overexpressing their specific inhibitors. J Biol Chem 280:15229\u201315237","journal-title":"J Biol Chem"},{"key":"103_CR53","doi-asserted-by":"crossref","first-page":"156","DOI":"10.1016\/S0169-328X(98)00116-8","volume":"58","author":"Z Fathi","year":"1998","unstructured":"Fathi Z, Battaglino PM, Iben LG, Li H, Baker E, Zhang D et al (1998) Molecular characterization, pharmacological properties and chromosomal localization of the human GALR2 galanin receptor. Brain Res Mol Brain Res 58:156\u2013169","journal-title":"Brain Res Mol Brain Res"},{"key":"103_CR54","doi-asserted-by":"crossref","first-page":"585","DOI":"10.1002\/ana.20433","volume":"57","author":"K Taguchi","year":"2005","unstructured":"Taguchi K, Yamagata HD, Zhong W, Kamino K, Akatsu H, Hata R et al (2005) Identification of hippocampus-related candidate genes for Alzheimer\u2019s disease. Ann Neurol 57:585\u2013588","journal-title":"Ann Neurol"}],"container-title":["Neurogenetics"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s10048-007-0103-3.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1007\/s10048-007-0103-3\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s10048-007-0103-3","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,8,25]],"date-time":"2021-08-25T20:39:22Z","timestamp":1629923962000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/s10048-007-0103-3"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2007,10,17]]},"references-count":54,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2008,2]]}},"alternative-id":["103"],"URL":"https:\/\/doi.org\/10.1007\/s10048-007-0103-3","relation":{},"ISSN":["1364-6745","1364-6753"],"issn-type":[{"value":"1364-6745","type":"print"},{"value":"1364-6753","type":"electronic"}],"subject":[],"published":{"date-parts":[[2007,10,17]]}}}