{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,10]],"date-time":"2026-04-10T14:15:33Z","timestamp":1775830533322,"version":"3.50.1"},"reference-count":13,"publisher":"Springer Science and Business Media LLC","issue":"8","license":[{"start":{"date-parts":[[2006,11,25]],"date-time":"2006-11-25T00:00:00Z","timestamp":1164412800000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Clin Rheumatol"],"published-print":{"date-parts":[[2007,6,27]]},"DOI":"10.1007\/s10067-006-0474-0","type":"journal-article","created":{"date-parts":[[2006,11,27]],"date-time":"2006-11-27T17:13:44Z","timestamp":1164647624000},"page":"1332-1334","source":"Crossref","is-referenced-by-count":45,"title":["Interleukin-18 as a mediator of systemic juvenile idiopathic arthritis"],"prefix":"10.1007","volume":"26","author":[{"given":"Marija","family":"Jelu\u0161i\u0107","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ivan Kre\u0161imir","family":"Luki\u0107","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lana","family":"Tambi\u0107-Bukovac","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Klara","family":"Dubrav\u010di\u0107","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ivan","family":"Mal\u010di\u0107","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Igor","family":"Rudan","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Drago","family":"Batini\u0107","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2006,11,25]]},"reference":[{"key":"474_CR1","doi-asserted-by":"crossref","first-page":"335","DOI":"10.1016\/j.pcl.2005.01.002","volume":"52","author":"KA Sullivan","year":"2005","unstructured":"Sullivan KA (2005) Inflammation in juvenile idiopathic arthritis. Pediatr Clin N Am 52:335\u2013357","journal-title":"Pediatr Clin N Am"},{"key":"474_CR2","doi-asserted-by":"crossref","first-page":"459","DOI":"10.1078\/0171-2985-00194","volume":"206","author":"H Mangge","year":"2002","unstructured":"Mangge H, Vojinovic J, Schauenstein K (2002) Do chemokines spark autoimmunity in juvenile and adult rheumatic disease? Immunobiology 206:459\u2013471","journal-title":"Immunobiology"},{"key":"474_CR3","doi-asserted-by":"crossref","first-page":"186","DOI":"10.1136\/adc.88.3.186","volume":"88","author":"N Wilkinson","year":"2003","unstructured":"Wilkinson N, Jackson G, Gardner-Medwin J (2003) Biologic therapies for juvenile arthritis. Arch Dis Child 88:186\u2013191","journal-title":"Arch Dis Child"},{"key":"474_CR4","doi-asserted-by":"crossref","first-page":"6435","DOI":"10.4049\/jimmunol.172.10.6435","volume":"172","author":"IM Kleer de","year":"2004","unstructured":"de Kleer IM, Wedderburn LR, Taams LS, Patel A, Varsani H, Klein M, de Jager W, Pugayung G, Giannoni F, Rijkers G, Albani S, Kuis W, Prakken B (2004) CD4+CD25bright regulatory T cells actively regulate inflammation in the joints of patients with the remitting form of juvenile idiopathic arthritis. J Immunol 172:6435\u20136443","journal-title":"J Immunol"},{"key":"474_CR5","doi-asserted-by":"crossref","first-page":"687","DOI":"10.1002\/art.20946","volume":"52","author":"F Benedetti de","year":"2005","unstructured":"de Benedetti F, Martini A (2005) Targeting the interleukin 6 receptor: a new treatment for systemic juvenile idiopathic arthritis? Arthritis Rheum 52:687\u2013693","journal-title":"Arthritis Rheum"},{"key":"474_CR6","doi-asserted-by":"crossref","first-page":"213","DOI":"10.1189\/jlb.0602313","volume":"73","author":"JA Gracie","year":"2003","unstructured":"Gracie JA, Robertson SE, McInnes IB (2003) Interleukin-18. J Leukoc Biol 73:213\u2013224","journal-title":"J Leukoc Biol"},{"key":"474_CR7","doi-asserted-by":"crossref","first-page":"402","DOI":"10.1111\/j.1365-2249.2004.02475.x","volume":"136","author":"JA Gracie","year":"2004","unstructured":"Gracie JA (2004) Interleukin-18 as a potential target in inflammatory arthritis. Clin Exp Immunol 136:402\u2013404","journal-title":"Clin Exp Immunol"},{"key":"474_CR8","first-page":"1991","volume":"25","author":"RE Petty","year":"1998","unstructured":"Petty RE, Southwood TR, Baum J, Bhettay E, Glass DN, Manners P, Maldonado-Cocco J, Suarez-Almazor M, Orozco-Alcala J, Prieur AM (1998) Revision of the proposed classification criteria for juvenile idiopathic arthritis: Durban, 1997. J Rheumatol 25:1991\u20131994","journal-title":"J Rheumatol"},{"key":"474_CR9","first-page":"2290","volume":"31","author":"CA Wallace","year":"2004","unstructured":"Wallace CA, Ruperto N, Giannini E, Childhood Arthritis and Rheumatology Research Alliance, Pediatric Rheumatology International Trials Organisation, Pediatric Rheumatology Collaborative Study Group (2004) Preliminary criteria for clinical remission for selected categories of juvenile idiopathic arthritis. J Rheumatol 31:2290\u20132294","journal-title":"J Rheumatol"},{"key":"474_CR10","doi-asserted-by":"crossref","first-page":"550","DOI":"10.1002\/1529-0131(200103)44:3<550::AID-ANR103>3.0.CO;2-5","volume":"44","author":"M Kawashima","year":"2001","unstructured":"Kawashima M, Yamamura M, Taniai M, Yamauchi H, Tanimoto T, Kurimoto M, Miyawaki S, Amano T, Takeuchi T, Makino H (2001) Levels of interleukin-18 and its binding inhibitors in the blood circulation of patients with adult-onset Still\u2019s disease. Arthritis Rheum 44:550\u2013560","journal-title":"Arthritis Rheum"},{"key":"474_CR11","doi-asserted-by":"crossref","first-page":"2539","DOI":"10.1002\/art.10389","volume":"46","author":"N Maeno","year":"2002","unstructured":"Maeno N, Takei S, Nomura Y, Imanaka H, Hokonohara M, Miyata K (2002) Highly elevated serum levels of interleukin-18 in systemic juvenile idiopathic arthritis but not in other juvenile idiopathic arthritis subtypes or in Kawasaki disease: comment on the article by Kawashima et al. Arthritis Rheum 46:2539\u20132541","journal-title":"Arthritis Rheum"},{"issue":"(Suppl 2)","key":"474_CR12","doi-asserted-by":"crossref","first-page":"ii100","DOI":"10.1136\/ard.61.suppl_2.ii100","volume":"61","author":"FY Liew","year":"2002","unstructured":"Liew FY, McInnes IB (2002) Role of interleukin 15 and interleukin 18 in inflammatory response. Ann Rheum Dis 61(Suppl 2):ii100\u2013ii102","journal-title":"Ann Rheum Dis"},{"key":"474_CR13","first-page":"369","volume":"29","author":"MP Scola","year":"2002","unstructured":"Scola MP, Thompson SD, Brunner HI, Tsoras MK, Witte D, van Dijk MA, Grom AA, Passo MH, Glass DN (2002) Interferon-y:interleukin 4 ratio and associated type 1 cytokine expression in juvenile rheumatoid arthritis synovial tissue. J Rheumatol 29:369\u2013378","journal-title":"J Rheumatol"}],"container-title":["Clinical Rheumatology"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s10067-006-0474-0.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1007\/s10067-006-0474-0\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s10067-006-0474-0","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,5,29]],"date-time":"2019-05-29T08:51:03Z","timestamp":1559119863000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/s10067-006-0474-0"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2006,11,25]]},"references-count":13,"journal-issue":{"issue":"8","published-print":{"date-parts":[[2007,6,27]]}},"alternative-id":["474"],"URL":"https:\/\/doi.org\/10.1007\/s10067-006-0474-0","relation":{},"ISSN":["0770-3198","1434-9949"],"issn-type":[{"value":"0770-3198","type":"print"},{"value":"1434-9949","type":"electronic"}],"subject":[],"published":{"date-parts":[[2006,11,25]]}}}