{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,3]],"date-time":"2026-06-03T15:55:02Z","timestamp":1780502102244,"version":"3.54.1"},"reference-count":26,"publisher":"Springer Science and Business Media LLC","issue":"12","license":[{"start":{"date-parts":[[2010,5,9]],"date-time":"2010-05-09T00:00:00Z","timestamp":1273363200000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Clin Rheumatol"],"published-print":{"date-parts":[[2010,12]]},"DOI":"10.1007\/s10067-010-1478-3","type":"journal-article","created":{"date-parts":[[2010,5,7]],"date-time":"2010-05-07T19:29:43Z","timestamp":1273260583000},"page":"1419-1425","source":"Crossref","is-referenced-by-count":76,"title":["Very low levels of vitamin D in systemic sclerosis patients"],"prefix":"10.1007","volume":"29","author":[{"given":"Paola","family":"Caramaschi","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alessandra","family":"Dalla Gassa","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Orazio","family":"Ruzzenente","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alessandro","family":"Volpe","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Viviana","family":"Ravagnani","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ilaria","family":"Tinazzi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Giovanni","family":"Barausse","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lisa M.","family":"Bambara","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Domenico","family":"Biasi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2010,5,9]]},"reference":[{"key":"1478_CR1","doi-asserted-by":"crossref","first-page":"662","DOI":"10.1210\/er.2004-0002","volume":"26","author":"S Nagpal","year":"2005","unstructured":"Nagpal S, Na S, Rathnachalam R (2005) Noncalcemic actions of vitamin D receptor ligands. Endocr Rev 26:662\u2013687","journal-title":"Endocr Rev"},{"key":"1478_CR2","doi-asserted-by":"crossref","first-page":"261","DOI":"10.1111\/j.1365-3083.2008.02127.x","volume":"68","author":"P Szodoray","year":"2008","unstructured":"Szodoray P, Nakken B, Gaal J et al (2008) The complex role of vitamin D in autoimmune diseases. Scand J Immunol 68:261\u2013269","journal-title":"Scand J Immunol"},{"key":"1478_CR3","doi-asserted-by":"crossref","first-page":"1387","DOI":"10.1002\/art.24785","volume":"61","author":"PW Wu","year":"2009","unstructured":"Wu PW, Rhew EY, Dyer AR et al (2009) 25-hydroxyvitamin D and cardiovascular risk factors in women with systemic lupus erythematosus. Arthritis Rheum 61:1387\u20131395","journal-title":"Arthritis Rheum"},{"key":"1478_CR4","doi-asserted-by":"crossref","first-page":"260","DOI":"10.1016\/j.jpeds.2009.02.033","volume":"155","author":"TB Wright","year":"2009","unstructured":"Wright TB, Shults J, Zemel LMB, BS BJM (2009) Hypovitaminosis D is associated with greater body mass index and disease activity in pediatric systemic lupus erythematosus. J Pediatr 155:260\u2013265","journal-title":"J Pediatr"},{"key":"1478_CR5","doi-asserted-by":"crossref","first-page":"334","DOI":"10.1006\/abbi.1999.1605","volume":"374","author":"CM Veldman","year":"2000","unstructured":"Veldman CM, Cantorna MT, Luca HF DE (2000) Expression of 1, 25-dihydroxyvitamin D3 receptor in the immune system. Arch Biochem Biophys 374:334\u2013338","journal-title":"Arch Biochem Biophys"},{"key":"1478_CR6","doi-asserted-by":"crossref","first-page":"3225","DOI":"10.1210\/en.141.9.3225","volume":"141","author":"JW Morgan","year":"2000","unstructured":"Morgan JW, Kouttab N, Ford D, Maizel AL (2000) Vitamin D-mediated gene regulation in phenotypically defined B cells sub-populations. Endocrinology 141:3225\u20133234","journal-title":"Endocrinology"},{"key":"1478_CR7","doi-asserted-by":"crossref","first-page":"1103","DOI":"10.1172\/JCI115072","volume":"87","author":"JM Lemire","year":"1991","unstructured":"Lemire JM, Archer DC (1991) 1, 25-dihydroxyvitamin D3 prevents the in vivo induction of murine experimental autoimmune encephalomyelitis. J Clin Invest 87:1103\u20131107","journal-title":"J Clin Invest"},{"issue":"suppl 1","key":"1478_CR8","doi-asserted-by":"crossref","first-page":"S265","DOI":"10.1016\/j.psyneuen.2009.05.023","volume":"34","author":"Fernandes Abreu DA de","year":"2009","unstructured":"de Abreu DA Fernandes, Eyles D, Feron F (2009) Vitamin D, a neuro-immunomodulator: implications for neurodegenerative and autoimmune diseases. Psyconeuroendocrinology 34(suppl 1):S265\u2013S277","journal-title":"Psyconeuroendocrinology"},{"key":"1478_CR9","doi-asserted-by":"crossref","first-page":"581","DOI":"10.1002\/art.1780230510","volume":"23","author":"Subcommittee for scleroderma criteria of the American Rheumatism Association diagnostic and therapeutic criteria committee","year":"1980","unstructured":"Subcommittee for scleroderma criteria of the American Rheumatism Association diagnostic and therapeutic criteria committee (1980) Preliminary criteria for the classification of systemic sclerosis (scleroderma). Arthritis Rheum 23:581\u2013590","journal-title":"Arthritis Rheum"},{"key":"1478_CR10","first-page":"202","volume":"15","author":"EC LeRoy","year":"1988","unstructured":"LeRoy EC, Black CM, Fleischmajer R et al (1988) Scleroderma (systemic sclerosis): classification, subsets and pathogenesis. J Rheumatol 15:202\u2013205","journal-title":"J Rheumatol"},{"issue":"suppl 29","key":"1478_CR11","first-page":"S5","volume":"21","author":"A Akesson","year":"2003","unstructured":"Akesson A, Fiori G, Krieg T, van den Hoogen FHJ, Seibold JR (2003) Assessment of skin, joint, tendon and muscle involvement. Clin Exp Rheumatol 21(suppl 29):S5\u2013S8","journal-title":"Clin Exp Rheumatol"},{"key":"1478_CR12","doi-asserted-by":"crossref","first-page":"592","DOI":"10.1136\/ard.60.6.592","volume":"60","author":"G Valentini","year":"2001","unstructured":"Valentini G, Della Rossa A, Bombardieri S et al (2001) European multicentre study to define disease activity for systemic sclerosis. Identification of disease activity variables and development of preliminary activity indexes. Ann Rheum Dis 60:592\u20138","journal-title":"Ann Rheum Dis"},{"key":"1478_CR13","first-page":"155","volume":"27","author":"M Cutolo","year":"2000","unstructured":"Cutolo M, Sulli A, Pizzorni C, Accardo S (2000) Nailfold videocapillaroscopy assessment of microvascular damage in systemic sclerosis. J Rheumatol 27:155\u2013160","journal-title":"J Rheumatol"},{"issue":"suppl 29","key":"1478_CR14","first-page":"S42","volume":"21","author":"TA Medsger Jr","year":"2003","unstructured":"Medsger TA Jr, Bombardieri S, Czjriak L, Scorza R, Della Rossa A, Bencivelli W (2003) Assessment of disease severity and prognosis. Clin Exp Rheumatol 21(suppl 29):S42\u20136","journal-title":"Clin Exp Rheumatol"},{"key":"1478_CR15","doi-asserted-by":"crossref","first-page":"1924","DOI":"10.3899\/jrheum.081287","volume":"36","author":"A Vacca","year":"2009","unstructured":"Vacca A, Cormier C, Piras M, Mathieu A, Kahan A, Allanore Y (2009) Vitamin D deficiency and insufficiency in 2 independent cohorts of patients with Systemic Sclerosis. J Rheumatol 36:1924\u20131929","journal-title":"J Rheumatol"},{"key":"1478_CR16","doi-asserted-by":"crossref","first-page":"2206","DOI":"10.3899\/jrheum.080192","volume":"35","author":"A Dovio","year":"2008","unstructured":"Dovio A, Data V, Carignola R et al (2008) Circulating osteoprotegerin and soluble RANK ligand in systemic sclerosis. J Rheumatol 35:2206\u20132213","journal-title":"J Rheumatol"},{"key":"1478_CR17","doi-asserted-by":"crossref","first-page":"2201","DOI":"10.3899\/jrheum.071171","volume":"35","author":"Y Braun-Moscovici","year":"2008","unstructured":"Braun-Moscovici Y, Furst DE, Markovits D et al (2008) Vitamin D, parathyroid hormone, and acroosteolysis in systemic sclerosis. J Rheumatol 35:2201\u20132205","journal-title":"J Rheumatol"},{"key":"1478_CR18","doi-asserted-by":"crossref","first-page":"385","DOI":"10.1196\/annals.1398.044","volume":"1109","author":"H Orbach","year":"2007","unstructured":"Orbach H, Zandman-Goddard G, Amital H et al (2007) Novel biomarkers in autoimmune diseases: prolactin, ferritin, vitamin D, and TPA levels in autoimmune diseases. Ann NY Acad Sci 1109:385\u2013400","journal-title":"Ann NY Acad Sci"},{"key":"1478_CR19","doi-asserted-by":"crossref","first-page":"114","DOI":"10.1016\/j.autrev.2005.05.009","volume":"5","author":"DL Kamen","year":"2006","unstructured":"Kamen DL, Cooper GS, Bouali H, Shaftman SR, Hollis BW, Gilkeson GS (2006) Vitamin D deficiency in systemic lupus erythematosus. Autoimmun Rev 5:114\u2013117","journal-title":"Autoimmun Rev"},{"key":"1478_CR20","doi-asserted-by":"crossref","first-page":"R123","DOI":"10.1186\/ar2533","volume":"10","author":"E Zold","year":"2008","unstructured":"Zold E, Szodoray P, Gaal J et al (2008) Vitamin D deficiency in undifferentiated connective tissue disease. Arthritis Res Ther 10:R123","journal-title":"Arthritis Res Ther"},{"key":"1478_CR21","doi-asserted-by":"crossref","first-page":"577","DOI":"10.1007\/s00198-003-1390-7","volume":"14","author":"G Isaia","year":"2003","unstructured":"Isaia G, Giorgino R, Rini GB, Bevilacqua M, Maugeri D, Adami S (2003) Prevalence of hypovitaminosis D in elderly women in Italy: clinical consequences and risk factors. Osteoporos Int 14:577\u2013582","journal-title":"Osteoporos Int"},{"key":"1478_CR22","doi-asserted-by":"crossref","first-page":"1122","DOI":"10.1093\/rheumatology\/35.11.1122","volume":"35","author":"C Bryan","year":"1996","unstructured":"Bryan C, Howard Y, Brennan P, Black Cm, Silman A (1996) Survival following the onset of scleroderma: results from a retrospective inception cohort study of the UK patient population. Br J Rheumatol 35:1122\u20136","journal-title":"Br J Rheumatol"},{"issue":"suppl 29","key":"1478_CR23","first-page":"S19","volume":"21","author":"M Matucci-Cerinic","year":"2003","unstructured":"Matucci-Cerinic M, D\u2019Angelo S, Denton CP, Vlachoyannopoulos P, Silver R (2003) Assessment of lung involvement. Clin Exp Rheumatol 21(suppl 29):S19\u2013S23","journal-title":"Clin Exp Rheumatol"},{"key":"1478_CR24","doi-asserted-by":"crossref","first-page":"207","DOI":"10.1677\/JOE-08-0241","volume":"200","author":"JN Artaza","year":"2009","unstructured":"Artaza JN, Norris KC (2009) Vitamin D reduces the expression of collagen and key profibrotic factors by inducing an antifibrotic phenotype in mesenchymal multipotent cells. J Endocrinol 200:207\u2013221","journal-title":"J Endocrinol"},{"key":"1478_CR25","doi-asserted-by":"crossref","first-page":"142","DOI":"10.1016\/j.jsbmb.2009.11.004","volume":"118","author":"AM Ramirez","year":"2010","unstructured":"Ramirez AM, Wongtrakool C, Welch T, Steinmeyer A, Zugel U, Roman J (2010) Vitamin D inhibition of pro-fibrotic effects on transforming growth factor \u03b21 in lung fibroblasts and epithelial cells. J Steroid Biochem Mol Biol 118:142\u2013150","journal-title":"J Steroid Biochem Mol Biol"},{"key":"1478_CR26","doi-asserted-by":"crossref","first-page":"1321","DOI":"10.1016\/S0002-9440(10)62351-6","volume":"166","author":"BC Willis","year":"2005","unstructured":"Willis BC, Liebler JM, Luby-Phelps K et al (2005) Induction of epithelial-mesenchymal transition in alveolar epithelial cells by transforming growth factor-beta1: potential role in idiopathic pulmonary fibrosis. Am J Pathol 166:1321\u20131332","journal-title":"Am J Pathol"}],"container-title":["Clinical Rheumatology"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s10067-010-1478-3.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1007\/s10067-010-1478-3\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s10067-010-1478-3","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,5,29]],"date-time":"2019-05-29T04:51:41Z","timestamp":1559105501000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/s10067-010-1478-3"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2010,5,9]]},"references-count":26,"journal-issue":{"issue":"12","published-print":{"date-parts":[[2010,12]]}},"alternative-id":["1478"],"URL":"https:\/\/doi.org\/10.1007\/s10067-010-1478-3","relation":{},"ISSN":["0770-3198","1434-9949"],"issn-type":[{"value":"0770-3198","type":"print"},{"value":"1434-9949","type":"electronic"}],"subject":[],"published":{"date-parts":[[2010,5,9]]}}}