{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,6]],"date-time":"2026-03-06T07:11:36Z","timestamp":1772781096781,"version":"3.50.1"},"reference-count":21,"publisher":"Springer Science and Business Media LLC","issue":"12","license":[{"start":{"date-parts":[[2016,8,17]],"date-time":"2016-08-17T00:00:00Z","timestamp":1471392000000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Clin Rheumatol"],"published-print":{"date-parts":[[2016,12]]},"DOI":"10.1007\/s10067-016-3380-0","type":"journal-article","created":{"date-parts":[[2016,8,16]],"date-time":"2016-08-16T18:00:45Z","timestamp":1471370445000},"page":"3057-3061","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":7,"title":["The \u22122518\u00a0A\/G polymorphism in the monocyte chemoattractant protein 1 gene (MCP-1) is associated with an increased risk of rheumatoid arthritis in Argentine patients"],"prefix":"10.1007","volume":"35","author":[{"given":"Emilia Saint","family":"Martin","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Emilce E.","family":"Schneeberger","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Federico M.","family":"Aranda","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Silvia Wingeyer","family":"Peres","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mar\u00eda","family":"del Carmen Valerio","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Maria","family":"de los Angeles Correa","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Fernando Dal","family":"Pra","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Liliana","family":"Martinez","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Graciela","family":"Remondino","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gabriela","family":"de Larra\u00f1aga","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gustavo","family":"Citera","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2016,8,17]]},"reference":[{"issue":"11","key":"3380_CR1","doi-asserted-by":"crossref","first-page":"656","DOI":"10.1038\/nrrheum.2012.153","volume":"8","author":"G Schett","year":"2012","unstructured":"Schett G, Gravallese E (2012) Bone erosion in rheumatoid arthritis: mechanisms, diagnosis and treatment. Nat Rev Rheumatol 8(11):656\u2013664","journal-title":"Nat Rev Rheumatol"},{"issue":"6","key":"3380_CR2","doi-asserted-by":"crossref","first-page":"313","DOI":"10.1089\/jir.2008.0027","volume":"29","author":"SL Deshmane","year":"2009","unstructured":"Deshmane SL, Kremlev S, Amini S, Sawaya BE (2009) Monocyte chemoattractant protein 1 (MCP-1): an overview. J Interf Cytokine Res 29(6):313\u2013326","journal-title":"J Interf Cytokine Res"},{"issue":"2","key":"3380_CR3","doi-asserted-by":"crossref","first-page":"488","DOI":"10.1172\/JCI115885","volume":"90","author":"PM Villiger","year":"1992","unstructured":"Villiger PM, Terkeltaub R, Lotz M (1992) Monocyte chemoattractant protein-1 (MCP-1) expression in human articular cartilage. J Clin Invest 90(2):488\u2013496","journal-title":"J Clin Invest"},{"issue":"2","key":"3380_CR4","doi-asserted-by":"crossref","first-page":"118","DOI":"10.1186\/ar149","volume":"3","author":"K Hayashida","year":"2001","unstructured":"Hayashida K, Nanki T, Girschik H, Yavuz S, Ochi T, Lipsky PE (2001) Synovial stromal cells from rheumatoid arthritis patients attract monocytes by producing MCP-1 and IL-8. Arthritis Res 3(2):118\u2013126","journal-title":"Arthritis Res"},{"issue":"6","key":"3380_CR5","doi-asserted-by":"crossref","first-page":"1720","DOI":"10.1002\/art.34449","volume":"64","author":"HS El-Gabalawy","year":"2012","unstructured":"El-Gabalawy HS, Robinson DB, Smolik I, Hart D, Elias B, Wong K, et al. (2012) Familial clustering of the serum cytokine profile in the relatives of rheumatoid arthritis patients. Arthritis Rheum 64(6):1720\u20131729","journal-title":"Arthritis Rheum"},{"issue":"1","key":"3380_CR6","doi-asserted-by":"crossref","first-page":"121","DOI":"10.1136\/ard.2006.057331","volume":"66","author":"S Rantapaa-Dahlqvist","year":"2007","unstructured":"Rantapaa-Dahlqvist S, Boman K, Tarkowski A, Hallmans G (2007) Up regulation of monocyte chemoattractant protein-1 expression in anti-citrulline antibody and immunoglobulin M rheumatoid factor positive subjects precedes onset of inflammatory response and development of overt rheumatoid arthritis. Ann Rheum Dis 66(1):121\u2013123","journal-title":"Ann Rheum Dis"},{"issue":"2","key":"3380_CR7","doi-asserted-by":"crossref","first-page":"344","DOI":"10.1006\/bbrc.1999.0796","volume":"259","author":"BH Rovin","year":"1999","unstructured":"Rovin BH, Lu L, Saxena R (1999) A novel polymorphism in the MCP-1 gene regulatory region that influences MCP-1 expression. Biochem Biophys Res Commun 259(2):344\u2013348","journal-title":"Biochem Biophys Res Commun"},{"issue":"7","key":"3380_CR8","doi-asserted-by":"crossref","first-page":"741","DOI":"10.1016\/S0198-8859(03)00090-9","volume":"64","author":"MF Gonz\u00e1lez-Escribano","year":"2003","unstructured":"Gonz\u00e1lez-Escribano MF, Torres B, Aguilar F, Rodr\u00edguez R, Garc\u00eda A, Valenzuela A, et al. (2003) MCP-1 promoter polymorphism in Spanish patients with rheumatoid arthritis. Hum Immunol 64(7):741\u2013744","journal-title":"Hum Immunol"},{"issue":"4","key":"3380_CR9","first-page":"235","volume":"32","author":"YH Lee","year":"2003","unstructured":"Lee YH, Kim HJ, Rho YH, Choi SJ, Ji JD, Song GG (2003) Functional polymorphisms in matrix metalloproteinase-1 and monocyte chemoattractant protein-1 and rheumatoid arthritis. Scand J Rheumatol 32(4):235\u2013239","journal-title":"Scand J Rheumatol"},{"issue":"5","key":"3380_CR10","doi-asserted-by":"crossref","first-page":"413","DOI":"10.1046\/j.1365-2370.2002.00346.x","volume":"29","author":"SY Hwang","year":"2002","unstructured":"Hwang SY, Cho ML, Park B, Kim JY, Kim JH, Min DJ, et al. (2002) Allelic frequency of the MCP-1 promoter \u22122518 polymorphism in the Korean population and in Korean patients with rheumatoid arthritis, systemic lupus erythematosus and adult onset Still\u2019s disease. Eur J Immunogenet 29(5):413\u2013416","journal-title":"Eur J Immunogenet"},{"issue":"3\u20134","key":"3380_CR11","doi-asserted-by":"crossref","first-page":"273","DOI":"10.1016\/j.molimm.2012.06.006","volume":"52","author":"M Pavkova Goldbergova","year":"2012","unstructured":"Pavkova Goldbergova M, Lipkova J, Pavek N, Gatterova J, Vasku A, Soucek M, et al. (2012) RANTES, MCP-1 chemokines and factors describing rheumatoid arthritis. Mol Immunol 52(3\u20134):273\u2013278","journal-title":"Mol Immunol"},{"issue":"9","key":"3380_CR12","doi-asserted-by":"crossref","first-page":"2569","DOI":"10.1002\/art.27584","volume":"62","author":"D Aletaha","year":"2010","unstructured":"Aletaha D, Neogi T, Silman AJ, Funovits J, Felson DT, Bingham CO 3rd, et al. (2010) 2010 rheumatoid arthritis classification criteria: an American College of Rheumatology\/European league against rheumatism collaborative initiative. Arthritis Rheum 62(9):2569\u20132581","journal-title":"Arthritis Rheum"},{"key":"3380_CR13","doi-asserted-by":"publisher","first-page":"77","DOI":"10.1186\/1471-2156-12-77","volume":"12","author":"ML Catelli","year":"2011","unstructured":"Catelli ML, Alvarez-Iglesias V, G\u00f3mez-Carballa A, Mosquera-Miguel A, Romanini C, Borosky A, et al. (2011) The impact of modern migrations on present-day multi-ethnic Argentina as recorded on the mitochondrial DNA genome. BMC Genet 12:77. doi: 10.1186\/1471-2156-12-77","journal-title":"BMC Genet"},{"issue":"1","key":"3380_CR14","doi-asserted-by":"crossref","first-page":"65","DOI":"10.1111\/j.1469-1809.2009.00556.x","volume":"74","author":"D Corach","year":"2010","unstructured":"Corach D, Lao O, Bobillo C, van Der Gaag K, Zuniga S, Vermeulen M, et al. (2010) Inferring continental ancestry of argentineans from autosomal, Y-chromosomal and mitochondrial DNA. Ann Hum Genet 74(1):65\u201376","journal-title":"Ann Hum Genet"},{"issue":"1","key":"3380_CR15","doi-asserted-by":"crossref","first-page":"44","DOI":"10.1002\/art.1780380107","volume":"38","author":"ML Prevoo","year":"1995","unstructured":"Prevoo ML, van\u2019t Hof MA, Kuper HH, van Leeuwen MA, van de Putte LB, van Riel PL (1995) Modified disease activity scores that include twenty-eight-joint counts. Development and validation in a prospective longitudinal study of patients with rheumatoid arthritis. Arthritis Rheum 38(1):44\u201348","journal-title":"Arthritis Rheum"},{"issue":"3","key":"3380_CR16","doi-asserted-by":"crossref","first-page":"110","DOI":"10.1097\/01.rhu.0000128732.58292.cd","volume":"10","author":"G Citera","year":"2004","unstructured":"Citera G, Arriola MS, Maldonado-Cocco JA, Rosemffet MG, Sanchez MM, Goni MA, et al. (2004) Validation and crosscultural adaptation of an Argentine Spanish version of the health assessment questionnaire disability index. J Clin Rheumatol 10(3):110\u2013115","journal-title":"J Clin Rheumatol"},{"issue":"1","key":"3380_CR17","first-page":"261","volume":"27","author":"D Heijde van der","year":"2000","unstructured":"van der Heijde D (2000) How to read radiographs according to the Sharp\/van der Heijde method. J Rheumatol 27(1):261\u2013263","journal-title":"J Rheumatol"},{"issue":"1","key":"3380_CR18","doi-asserted-by":"crossref","first-page":"83","DOI":"10.1007\/s10238-012-0221-6","volume":"14","author":"SA Mu\u00f1oz","year":"2014","unstructured":"Mu\u00f1oz SA, Aranda F, Allievi A, Orden AO, Peres Wingeyer S, Trobo R, et al. (2014) 4G\/5G plasminogen activator inhibitor-1 and \u2212308\u00a0A\/G tumor necrosis factor-\u03b1 promoter gene polymorphisms in Argentinean lupus patients: focus on lupus nephritis. Clin Exp Med 14(1):83\u201389","journal-title":"Clin Exp Med"},{"issue":"4","key":"3380_CR19","doi-asserted-by":"crossref","first-page":"546","DOI":"10.1007\/s10067-006-0347-6","volume":"26","author":"AR Ozyurek","year":"2007","unstructured":"Ozyurek AR, Gurses D, Ulger Z, Levent E, Bakiler AR, Berdeli A (2007) Allelic frecuency of the MCP-1 promoter \u22122518 polymorphism in the turkish population and in turkish patients with juvenile rheumatoid arthritis. Clin Rheumatol 26(4):546\u2013550","journal-title":"Clin Rheumatol"},{"issue":"3","key":"3380_CR20","first-page":"65","volume":"62","author":"YH Lee","year":"2016","unstructured":"Lee YH, Bae SC (2016) Monocyte chemoattractant protein-1 promoter \u22122518 polymorphism and susceptibility to vasculitis, rheumatoid arthritis, and multiple sclerosis: a meta-analysis. Cell Mol Bioj (Noisy-le-grand) 62(3):65\u201371","journal-title":"Cell Mol Bioj (Noisy-le-grand)"},{"issue":"5","key":"3380_CR21","doi-asserted-by":"crossref","first-page":"1169","DOI":"10.1007\/s10067-015-3060-5","volume":"35","author":"S Chen","year":"2016","unstructured":"Chen S, Deng S, Hu C, Li J, Wen X, Wu Z, et al. (2016) Association of MCP-1-2518\u00a0A\/G poymorphism with susceptibility to autoimmune diseases: a meta analysis. Clin Rheumatol 35(5):1169\u20131179","journal-title":"Clin Rheumatol"}],"container-title":["Clinical Rheumatology"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s10067-016-3380-0.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1007\/s10067-016-3380-0\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s10067-016-3380-0.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2017,6,24]],"date-time":"2017-06-24T16:49:50Z","timestamp":1498322990000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/s10067-016-3380-0"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2016,8,17]]},"references-count":21,"journal-issue":{"issue":"12","published-print":{"date-parts":[[2016,12]]}},"alternative-id":["3380"],"URL":"https:\/\/doi.org\/10.1007\/s10067-016-3380-0","relation":{},"ISSN":["0770-3198","1434-9949"],"issn-type":[{"value":"0770-3198","type":"print"},{"value":"1434-9949","type":"electronic"}],"subject":[],"published":{"date-parts":[[2016,8,17]]}}}