{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,21]],"date-time":"2026-09-21T00:37:26Z","timestamp":1789951046855,"version":"4.0.1"},"reference-count":43,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2016,11,18]],"date-time":"2016-11-18T00:00:00Z","timestamp":1479427200000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0"}],"funder":[{"name":"This work was supported by the NIAMS Intramural Research Program","award":["Z01 AR041184"],"award-info":[{"award-number":["Z01 AR041184"]}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Clin Rheumatol"],"published-print":{"date-parts":[[2017,1]]},"DOI":"10.1007\/s10067-016-3469-5","type":"journal-article","created":{"date-parts":[[2016,11,18]],"date-time":"2016-11-18T00:47:58Z","timestamp":1479430078000},"page":"143-154","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":22,"title":["Generation and differentiation of induced pluripotent stem cells reveal ankylosing spondylitis risk gene expression in bone progenitors"],"prefix":"10.1007","volume":"36","author":[{"given":"Gerlinde","family":"Layh-Schmitt","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shajia","family":"Lu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fatemeh","family":"Navid","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Stephen R.","family":"Brooks","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Emily","family":"Lazowick","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kathryn M.","family":"Davis","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Cristina","family":"Montagna","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Massimo","family":"Gadina","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Robert A.","family":"Colbert","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2016,11,18]]},"reference":[{"key":"3469_CR1","doi-asserted-by":"crossref","first-page":"2563","DOI":"10.1056\/NEJMra1406182","volume":"26","author":"JD Taurog","year":"2016","unstructured":"Taurog JD, Chhabbra A, Colbert RA (2016) Axial spondyloarthritis and ankylosing spondylitis. New Engl J Med 26:2563\u20132574","journal-title":"New Engl J Med"},{"key":"3469_CR2","doi-asserted-by":"crossref","first-page":"777","DOI":"10.1136\/ard.2009.108233","volume":"68","author":"M Rudwaleit","year":"2009","unstructured":"Rudwaleit M, van der Heijde D, Landewe R, Listing J, Akkoc N, Brandt J, Braun J, Chou CT, Collantes-Estevez E, Dougados M, Emery P, van der Horst-Bruinsma IE, Inman R, Khan MA, Leirisalo-Repo M, van der Linden S, Maksymowych WP, Mielants H, Olivieri I, Sturrock R, de Vlam K, Sieper J (2009) The development of Assessment of SpondyloArthritis international Society classification criteria for axial spondyloarthritis (part II): validation and final selection. Ann Rheum Dis 68:777\u2013783","journal-title":"Ann Rheum Dis"},{"key":"3469_CR3","doi-asserted-by":"crossref","first-page":"81","DOI":"10.1038\/nrrheum.2015.133","volume":"12","author":"MA Brown","year":"2016","unstructured":"Brown MA, Kenna T, Wordsworth BP (2016) Genetics of ankylosing spondylitis-insights into pathogenesis. Nat Rev Rheumatol 12:81\u201391","journal-title":"Nat Rev Rheumatol"},{"key":"3469_CR4","doi-asserted-by":"crossref","first-page":"231","DOI":"10.1002\/art.38291","volume":"66","author":"JA Smith","year":"2014","unstructured":"Smith JA, Colbert RA (2014) Review: the interleukin-23\/interleukin-17 axis in spondyloarthritis pathogenesis: Th17 and beyond. Arthritis Rheum 66:231\u2013241","journal-title":"Arthritis Rheum"},{"key":"3469_CR5","doi-asserted-by":"crossref","first-page":"1069","DOI":"10.1038\/nm.2817","volume":"18","author":"JP Sherlock","year":"2012","unstructured":"Sherlock JP, Joyce-Shaikh B, Turner SP, Chao CC, Sathe M, Grein J, Gorman DM, Bowman EP, McClanahan TK, Yearley JH, Eberl G, Buckley CD, Kastelein RA, Pierce RH, Laface DM, Cua DJ (2012) IL-23 induces spondyloarthropathy by acting on ROR-\u03b3t+CD3+CD4\u2212CD8\u2013 entheseal resident T cells. Nat Med 18:1069\u20131076","journal-title":"Nat Med"},{"key":"3469_CR6","doi-asserted-by":"crossref","first-page":"499","DOI":"10.1002\/art.1780380407","volume":"38","author":"J Braun","year":"1995","unstructured":"Braun J, Bollow M, Neure L, Seipelt E, Seyrekbasan F, Herbst H, Eggens U, ADistler A, Sieper J (1995) Use of immunohistologic and in situ hybridization techniques in the examination of sacroiliac joint biopsy specimens from patients with ankylosing spondylitis. Arthritis Rheum 38:499\u2013505","journal-title":"Arthritis Rheum"},{"key":"3469_CR7","doi-asserted-by":"crossref","first-page":"1522","DOI":"10.1002\/art.37937","volume":"65","author":"H Appel","year":"2013","unstructured":"Appel H, Maier R, Bleil J, Hempfing A, Loddenkemper C, Schlichting U, Syrbe U, Sieper J (2013) In situ analysis of interleukin-23- and interleukin-12-positive cells in the spine of patients with ankylosing spondylitis. Arthritis Rheum 65:1522\u20131529","journal-title":"Arthritis Rheum"},{"key":"3469_CR8","doi-asserted-by":"crossref","first-page":"R95","DOI":"10.1186\/ar3370","volume":"13","author":"H Appel","year":"2011","unstructured":"Appel H, Maier R, Wu P, Scheer R, Hempfing A, Kayser R, Thiel A, Radbruch A, Loddenkemper C, Sieper J (2011) Analysis of IL-17(+) cells in facet joints of patients with spondyloarthritis suggests that the innate immune pathway might be of greater relevance than the Th17-mediated adaptive immune response. Arthritis Res Ther 13:R95","journal-title":"Arthritis Res Ther"},{"issue":"5","key":"3469_CR9","doi-asserted-by":"crossref","first-page":"715","DOI":"10.1016\/j.berh.2010.05.001","volume":"24","author":"D Poddubnyy","year":"2010","unstructured":"Poddubnyy D, Appel H, Sieper J (2010) Investigation of involved tissue in axial spondyloarthritis--what have we learnt from immunohistochemical studies? Best Pract Res Clin Rheumatol 24(5):715\u2013719","journal-title":"Best Pract Res Clin Rheumatol"},{"key":"3469_CR10","doi-asserted-by":"crossref","first-page":"817","DOI":"10.1136\/annrheumdis-2013-204248","volume":"73","author":"D Poddubnyy","year":"2014","unstructured":"Poddubnyy D, Hermann K-G, Callhoff J, Listing J, Sieper J (2014) Ustekinumab for the treatment of patients with active ankylosing spondylitis: results of a 28-week, prospective, open-label, proof-of concept study (TOPAS). Ann Rheum Dis 73:817\u2013823","journal-title":"Ann Rheum Dis"},{"key":"3469_CR11","doi-asserted-by":"crossref","first-page":"2534","DOI":"10.1056\/NEJMoa1505066","volume":"373","author":"D Baeten","year":"2015","unstructured":"Baeten D, Sieper J, Braun J, Baraliakos X, Dougados M, Emry P, Deodhar A, Porter B, Martin R, Andersson M, Mpofu S, Richards HB (2015) Secukinumab, an interleukin-17A inhibitor in ankylosing spondylitis. N Engl J Med 373:2534\u20132548","journal-title":"N Engl J Med"},{"key":"3469_CR12","doi-asserted-by":"crossref","first-page":"861","DOI":"10.1016\/j.cell.2007.11.019","volume":"131","author":"K Takahashi","year":"2007","unstructured":"Takahashi K, Tanabe K, Ohnuki M, Narita M, Ichisaka T, Tomoda K, Yamanaka S (2007) Induction of pluripotent stem cells from adult human fibroblasts by defined factors. Cell 131:861\u2013872","journal-title":"Cell"},{"key":"3469_CR13","doi-asserted-by":"crossref","first-page":"1917","DOI":"10.1126\/science.1151526","volume":"18","author":"J Yu","year":"2007","unstructured":"Yu J, Vodyanik MA, Smuga-Otto K, Antosiewicz-Bourget J, Frane JL, Tian S, Nie J, Jonsdottir GA, Ruotti V, Stewart R, Slukvin IL, Thompson JA (2007) Induced pluripotent stem cell lines derived from human somatic cells. Science 18:1917\u20131920","journal-title":"Science"},{"key":"3469_CR14","doi-asserted-by":"crossref","first-page":"2029","DOI":"10.1038\/nprot.2012.130","volume":"7","author":"J Beers","year":"2012","unstructured":"Beers J, Gulbranson DR, George N, Siniscalchi LI, Jones J, Thomson JA, Chen G (2012) Passaging and colony expansion of human pluripotent stem cells by enzyme-free dissociation in chemically defined culture conditions. Nat Prot 7:2029\u20132040","journal-title":"Nat Prot"},{"key":"3469_CR15","doi-asserted-by":"crossref","first-page":"147","DOI":"10.1038\/mt.2014.195","volume":"23","author":"RK Merling","year":"2015","unstructured":"Merling RK, Sweeney CL, Chu J, Bodansky A, Choi U, Priel DL, Kuhns DB, Wang H, Vasilevsky S, De Ravin SS, Winkler T, Dunbar CE, Zou J, Zarember KA, Gallin JI, Holland SM, Malech HL (2015) An AAVS1-targeted minigene platform for correction of iPSCs from all five types of chronic granulomatous disease. Mol Ther 23:147\u2013157","journal-title":"Mol Ther"},{"key":"3469_CR16","doi-asserted-by":"crossref","first-page":"663","DOI":"10.1016\/j.cell.2006.07.024","volume":"126","author":"K Takahashi","year":"2006","unstructured":"Takahashi K, Yamanaka S (2006) Induction of pluripotent stem cells from mouse embryonic and adult fibroblast cultures by defined factors. Cell 126:663\u2013676","journal-title":"Cell"},{"key":"3469_CR17","doi-asserted-by":"crossref","first-page":"2956","DOI":"10.1182\/blood-2003-09-3314","volume":"103","author":"B Bhattacharya","year":"2004","unstructured":"Bhattacharya B, Miura T, Brandenberger R, Mejido J, Luo Y, Yang AX, Joshi BH, Ginis I, Thies RS, Amit M, Lyons I, Condie BG, Itskovitz-Eldor J, Rao MS, Puri KK (2004) Gene expression in human embryonic stem cell lines: unique molecular signature. Blood 103:2956\u20132964","journal-title":"Blood"},{"key":"3469_CR18","doi-asserted-by":"crossref","first-page":"803","DOI":"10.1038\/nbt1318","volume":"25","author":"O Adewumi","year":"2007","unstructured":"International Stem Cell Initiative, Adewumi O, Aflatoonian B, Ahrlund-Richter L, Amit M, Andrews PW, Beighton G, Bello PA, Benvenisty N, Berry LS et al (2007) Characterization of human embryonic stem cell lines by the International Stem Cell Initiative. Nat Biotech 25:803\u2013816","journal-title":"Nat Biotech"},{"key":"3469_CR19","doi-asserted-by":"crossref","first-page":"C1080","DOI":"10.1152\/ajpcell.00359.2012","volume":"304","author":"M Wang","year":"2013","unstructured":"Wang M, Yu Q, Wang L, Gu H (2013) Distinct patterns of histone modifications at cardiac-specific gene promoters between cardiac stem cells and mesenchymal stem cells. Am J of Physiol Cell Physiol 304:C1080\u2013C1090","journal-title":"Am J of Physiol Cell Physiol"},{"key":"3469_CR20","doi-asserted-by":"crossref","first-page":"2","DOI":"10.1016\/j.molimm.2013.06.013","volume":"57","author":"PC Robinson","year":"2014","unstructured":"Robinson PC, Brown MA (2014) Genetics of ankylosing spondylitis. Mol Immunol 57:2\u201311","journal-title":"Mol Immunol"},{"key":"3469_CR21","doi-asserted-by":"crossref","first-page":"661","DOI":"10.1038\/nrg3502","volume":"14","author":"M Parkes","year":"2013","unstructured":"Parkes M, Cortes A, van Heel DA, Brown MA (2013) Genetic insights into common pathways and complex relationships among immune-mediated diseases. Nat Rev Genet 14:661\u2013673","journal-title":"Nat Rev Genet"},{"key":"3469_CR22","doi-asserted-by":"crossref","first-page":"221","DOI":"10.1016\/j.ajhg.2014.12.024","volume":"96","author":"MJ Lewis","year":"2015","unstructured":"Lewis MJ, Vyse S, Shields AM, Boeltz S, Gordon PA, Spector TD, Lehner PJ, Walczak H, Vyse TJ (2015) UBE2L3 polymorphism amplifies NF-kappaB activation and promotes plasma cell development, linking linear ubiquitination to multiple autoimmune diseases. Am J Hum Genet 96:221\u2013234","journal-title":"Am J Hum Genet"},{"key":"3469_CR23","doi-asserted-by":"crossref","first-page":"327","DOI":"10.1091\/mbc.E14-06-1057","volume":"26","author":"KS Plafker","year":"2015","unstructured":"Plafker KS, Plafker SM (2015) The ubiquitin-conjugating enzyme UBE2E3 and its import receptor importin-11 regulate the localization and activity of the antioxidant transcription factor NRF2. Mol Biol of the Cell 26:327\u2013338","journal-title":"Mol Biol of the Cell"},{"key":"3469_CR24","doi-asserted-by":"crossref","first-page":"401","DOI":"10.1146\/annurev-pharmtox-011112-140320","volume":"53","author":"Q Ma","year":"2013","unstructured":"Ma Q (2013) Role of nrf2 in oxidative stress and toxicity. Ann Rev Pharm and Tox 53:401\u2013426","journal-title":"Ann Rev Pharm and Tox"},{"key":"3469_CR25","doi-asserted-by":"crossref","first-page":"29","DOI":"10.1186\/1750-1326-6-29","volume":"6","author":"G Ren","year":"2011","unstructured":"Ren G, Ma Z, Hui M, Kudo LC, Hui KS, Karsten SL (2011) Cu, Zn-superoxide dismutase 1 (SOD1) is a novel target of Puromycin-sensitive aminopeptidase (PSA\/NPEPPS): PSA\/NPEPPS is a possible modifier of amyotrophic lateral sclerosis. Mol Neurodegen 6:29","journal-title":"Mol Neurodegen"},{"key":"3469_CR26","doi-asserted-by":"crossref","first-page":"4573","DOI":"10.1093\/hmg\/ddq385","volume":"19","author":"FM Menzies","year":"2010","unstructured":"Menzies FM, Hourez R, Imarisio S, Raspe M, Sadiq O, Chandraratna D, O'Kane C, Rock KL, Reits E, Goldberg AL, Rubinsztein DC (2010) Puromycin-sensitive aminopeptidase protects against aggregation-prone proteins via autophagy. Hum Mol Genet 19:4573\u20134586","journal-title":"Hum Mol Genet"},{"key":"3469_CR27","doi-asserted-by":"crossref","first-page":"4161","DOI":"10.4049\/jimmunol.169.8.4161","volume":"169","author":"F Levy","year":"2002","unstructured":"Levy F, Burri L, Morel S, Peitrequin AL, Levi N, Bachi A, Hellman U, Van den Eynde BJ, Servis C (2002) The final N-terminal trimming of a subaminoterminal proline-containing HLA class I-restricted antigenic peptide in the cytosol is mediated by two peptidases. J Immunol 169:4161\u20134171","journal-title":"J Immunol"},{"key":"3469_CR28","doi-asserted-by":"crossref","first-page":"7379","DOI":"10.4049\/jimmunol.0901489","volume":"183","author":"E Kim","year":"2009","unstructured":"Kim E, Kwak H, Ahn K (2009) Cytosolic aminopeptidases influence MHC class I-mediated antigen presentation in an allele-dependent manner. J Immunol 183:7379\u20137387","journal-title":"J Immunol"},{"key":"3469_CR29","doi-asserted-by":"crossref","first-page":"521","DOI":"10.1038\/gene.2014.46","volume":"15","author":"N Agrawal","year":"2014","unstructured":"Agrawal N, Brown MA (2014) Genetic associations and functional characterization of M1 aminopeptidases and immune-mediated diseases. Genes Immun 15:521\u2013527","journal-title":"Genes Immun"},{"key":"3469_CR30","doi-asserted-by":"crossref","first-page":"73","DOI":"10.1038\/ng.1005","volume":"44","author":"Z Lin","year":"2011","unstructured":"Lin Z, Bei JX, Shen M, Li Q, Liao Z, Zhang Y, Lv Q, Wei Q, Low HQ, Guo YM, Cao S, Yang M, Hu Z, Xu M, Wang X, Wei Y, Li L, Li C, Li T, Huang J, Pan Y, Jin O, Wu Y, Wu J, Guo Z, He P, Hu S, Wu H, Song H, Zhan F, Liu S, Gao G, Liu Z, Li Y, Xiao C, Li J, Ye Z, He W, Liu D, Shen L, Huang A, Wu H, Tao Y, Pan X, Yu B, Tai ES, Zeng YX, Ren EC, Shen Y, Liu J, Gu J (2011) A genome-wide association study in Han Chinese identifies new susceptibility loci for ankylosing spondylitis. Nat Genet 44:73\u201377","journal-title":"Nat Genet"},{"key":"3469_CR31","doi-asserted-by":"crossref","first-page":"81","DOI":"10.1016\/j.jprot.2015.01.002","volume":"116","author":"M Rose-Martel","year":"2015","unstructured":"Rose-Martel M, Smiley S, Hincke MT (2015) Novel identification of matrix proteins involved in calcitic biomineralization. J Proteome 116:81\u201396","journal-title":"J Proteome"},{"key":"3469_CR32","doi-asserted-by":"crossref","first-page":"863","DOI":"10.1016\/j.jhep.2015.05.005","volume":"63","author":"H Xia","year":"2013","unstructured":"Xia H, Jianxiang C, Shi M, Gao H, Karthik S, Pratap SV, Ooi LL, Hui KM (2013) EDIL3 is a novel regulator of epithelial mesenchymal transition controlling early recurrence of hepatocellular carcinoma. J Hepatol 63:863\u2013873","journal-title":"J Hepatol"},{"key":"3469_CR33","doi-asserted-by":"crossref","first-page":"465","DOI":"10.1038\/ni.2260","volume":"13","author":"MA Eskan","year":"2013","unstructured":"Eskan MA, Jotwani R, Abe T, Chmelar J, Lim JH, Liang S, Ciero PA, Krauss JL, Li F, Rauner M, Hofbauer LC, Choi EY, Chung KJ, Hashim A, Curtis MA, Chavakis T, Hajishengallis G (2013) The leukocyte integrin antagonist Del-1 inhibits IL-17-mediated inflammatory bone loss. Nat Immunol 13:465\u2013473","journal-title":"Nat Immunol"},{"key":"3469_CR34","doi-asserted-by":"crossref","first-page":"572","DOI":"10.1007\/s00586-010-1598-0","volume":"20","author":"T Urano","year":"2011","unstructured":"Urano T, Narusawa K, Shiraki M, Sasaki N, Hosoi T, Ouchi Y, Nakamura T, Inoue S (2011) Single-nucleotide polymorphism in the hyaluronan and proteoglycan link protein 1 (HAPLN1) gene is associated with spinal osteophyte formation and disc degeneration in Japanese women. Eur Spine J 20:572\u2013577","journal-title":"Eur Spine J"},{"key":"3469_CR35","doi-asserted-by":"crossref","first-page":"6270","DOI":"10.1074\/jbc.M114.602979","volume":"290","author":"J Ousingsawat","year":"2015","unstructured":"Ousingsawat J, Wanitchakool P, Schreiber R, Wuelling M, Vortkamp A, Kunzelmann K (2015) Anoctamin-6 controls bone mineralization by activating the calcium transporter NCX1. J Biol Chem 290:6270\u20136280","journal-title":"J Biol Chem"},{"issue":"2","key":"3469_CR36","doi-asserted-by":"crossref","first-page":"246","DOI":"10.1002\/jbmr.1751","volume":"28","author":"HW Ehlen","year":"2013","unstructured":"Ehlen HW, Chinenkova M, Moser M, Munter HM, Krause Y, Gross S, Brachvogel B, Wuelling M, Kornak U, Vortkamp A (2013) Inactivation of anoctamin-6\/Tmem16f, a regulator of phosphatidylserine scrambling in osteoblasts, leads to decreased mineral deposition in skeletal tissues. J Bone Min Res 28(2):246\u2013259","journal-title":"J Bone Min Res"},{"key":"3469_CR37","doi-asserted-by":"crossref","first-page":"1141","DOI":"10.1016\/j.cell.2005.12.045","volume":"124","author":"W Wei","year":"2006","unstructured":"Wei W, Lu Q, Chaudry GJ, Leppla SH, Cohen SN (2006) The LDL receptor-related protein LRP6 mediates internalization and lethality of anthrax toxin. Cell 124:1141\u20131154","journal-title":"Cell"},{"key":"3469_CR38","doi-asserted-by":"crossref","first-page":"23748","DOI":"10.1074\/jbc.M508365200","volume":"281","author":"X Li","year":"2006","unstructured":"Li X, Thyssen G, Beliakoff J, Sun Z (2006) The novel PIAS-like protein hZimp10 enhances Smad transcriptional activity. J Biol Chem 281:23748\u201323756","journal-title":"J Biol Chem"},{"key":"3469_CR39","doi-asserted-by":"crossref","first-page":"1704","DOI":"10.1053\/j.gastro.2011.02.046","volume":"140","author":"JH Cho","year":"2011","unstructured":"Cho JH, Brant SR (2011) Recent insights into the genetics of inflammatory bowel disease. Gastroenterology 140:1704\u20131712","journal-title":"Gastroenterology"},{"key":"3469_CR40","doi-asserted-by":"crossref","first-page":"295","DOI":"10.1038\/ng.543","volume":"42","author":"PC Dubois","year":"2010","unstructured":"Dubois PC, Trynka G, Franke L, Hunt KA, Romanos J, Curtotti A, Zhernakova A, Heap GA, Adany R, Aromaa A (2010) Multiple common variants for celiac disease influencing immune gene expression. Nat Genet 42:295\u2013302","journal-title":"Nat Genet"},{"key":"3469_CR41","doi-asserted-by":"crossref","first-page":"897","DOI":"10.1002\/ana.22609","volume":"70","author":"NA Patsopoulos","year":"2011","unstructured":"Patsopoulos NA, Bayer Pharma MS Genetics Working Group., Steering Committees of Studies Evaluating IFN\u03b2-1b and a CCR1-Antagonist., ANZgene Consortium., GeneMsa., International Multiple Sclerosis Genetics Consortium, Esposito F et al (2011) Genome-wide meta-analysis identifies novel multiple sclerosis susceptibility loci. Ann Neurol 70:897\u2013912","journal-title":"Ann Neurol"},{"key":"3469_CR42","doi-asserted-by":"crossref","first-page":"345","DOI":"10.1136\/jmedgenet-2013-102233","volume":"51","author":"Y Sun","year":"2014","unstructured":"Sun Y, Zuo X, Zheng X, Zhou F, Liang B, Liu H, Chang R, Gao J, Sheng Y, Cui H, Wang W, Andiappan AK, Rotzschke O, Yang S, Sun L, Zhang F, Zhang X, Ren Y, Liu J (2014) A comprehensive association analysis confirms ZMIZ1 to be a susceptibility gene for vitiligo in Chinese population. J Med Gen 51:345\u2013353","journal-title":"J Med Gen"},{"key":"3469_CR43","doi-asserted-by":"crossref","first-page":"430","DOI":"10.1002\/art.39433","volume":"68","author":"Z Xie","year":"2016","unstructured":"Xie Z, Wang P, Li X, Deng W, Zhang X, Su H, Deng L, Wu Y, Shen H (2016) Imbalance between bone morphogenetic protein 2 and noggin induces abnormal osteogenic differentiation of mesenchymal stem cells in ankylosing spondylitis. Arthritis Rheum 68:430\u2013440","journal-title":"Arthritis Rheum"}],"container-title":["Clinical Rheumatology"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s10067-016-3469-5.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1007\/s10067-016-3469-5\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s10067-016-3469-5.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2017,6,24]],"date-time":"2017-06-24T23:54:37Z","timestamp":1498348477000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/s10067-016-3469-5"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2016,11,18]]},"references-count":43,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2017,1]]}},"alternative-id":["3469"],"URL":"https:\/\/doi.org\/10.1007\/s10067-016-3469-5","relation":{},"ISSN":["0770-3198","1434-9949"],"issn-type":[{"value":"0770-3198","type":"print"},{"value":"1434-9949","type":"electronic"}],"subject":[],"published":{"date-parts":[[2016,11,18]]}}}