{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,1]],"date-time":"2026-04-01T00:04:48Z","timestamp":1775001888301,"version":"3.50.1"},"reference-count":40,"publisher":"Springer Science and Business Media LLC","issue":"11","license":[{"start":{"date-parts":[[2017,9,13]],"date-time":"2017-09-13T00:00:00Z","timestamp":1505260800000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Clin Rheumatol"],"published-print":{"date-parts":[[2017,11]]},"DOI":"10.1007\/s10067-017-3816-1","type":"journal-article","created":{"date-parts":[[2017,9,13]],"date-time":"2017-09-13T10:23:03Z","timestamp":1505298183000},"page":"2541-2548","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":5,"title":["Knee osteoarthritis and associated cardio-metabolic clusters in a tertiary hospital in Nigeria"],"prefix":"10.1007","volume":"36","author":[{"given":"Abubakar","family":"Yerima","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Olufemi","family":"Adelowo","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2017,9,13]]},"reference":[{"key":"3816_CR1","doi-asserted-by":"crossref","first-page":"1465","DOI":"10.1016\/j.joca.2012.07.022","volume":"20","author":"MC Hochberg","year":"2012","unstructured":"Hochberg MC (2012) Osteoarthritis year 2012 in review: clinical. Osteoarthr Cartil 20:1465\u20131469","journal-title":"Osteoarthr Cartil"},{"key":"3816_CR2","unstructured":"World Health Organisation Fact sheet WHO (2014) Obesity and overweight Fact sheet N0 311 available at: \nhttp:\/\/www.who.int\/mediacentre\/factsheets\/fs311\/en\/\n\n updated 2016"},{"key":"3816_CR3","doi-asserted-by":"crossref","first-page":"91","DOI":"10.1136\/ard.60.2.91","volume":"60","author":"G Peat","year":"2001","unstructured":"Peat G, McCarney R, Croft P (2001) Knee pain and osteoarthritis in older adults: a review of community burden and current use of primary health care. Ann Rheum Dis 60:91\u201397","journal-title":"Ann Rheum Dis"},{"key":"3816_CR4","doi-asserted-by":"crossref","first-page":"72","DOI":"10.1136\/oem.2007.032466","volume":"65","author":"LK Jensen","year":"2008","unstructured":"Jensen LK (2008) Knee osteoarthritis: influence of work involving heavy lifting, kneeling, climbing stairs or ladders, or kneeling\/squatting combined with heavy lifting. Occup Environ Med 65:72\u201389","journal-title":"Occup Environ Med"},{"key":"3816_CR5","first-page":"668","volume":"55","author":"DT Felson","year":"1996","unstructured":"Felson DT (1996) Does\u2002excess\u2002weight\u2002cause\u2002osteoarthritis\u2002and,\u2002if so,\u2002why? Ann\u2002Rheum\u2002Dis 55:668\u2013670","journal-title":"Ann\u2002Rheum\u2002Dis"},{"key":"3816_CR6","doi-asserted-by":"crossref","first-page":"761","DOI":"10.1136\/ard.2008.106930","volume":"69","author":"E Yusuf","year":"2010","unstructured":"Yusuf E, Nelissen RG, Ioan-Facsinay A et al (2010) Association between weight or body mass\u2002index and hand osteoarthritis: a systematic review. Ann Rheum 69:761\u2013765","journal-title":"Ann Rheum"},{"issue":"5","key":"3816_CR7","doi-asserted-by":"crossref","first-page":"586","DOI":"10.2174\/138945010791011857","volume":"11","author":"F Iannone","year":"2010","unstructured":"Iannone F, Lapadula G (2010) Obesity and inflammation\u2014targets for OA therapy. Curr Drug Targets 11(5):586\u2013598","journal-title":"Curr Drug Targets"},{"issue":"5","key":"3816_CR8","doi-asserted-by":"crossref","first-page":"533","DOI":"10.1097\/BOR.0b013e32833b4682","volume":"22","author":"MR Sowers","year":"2010","unstructured":"Sowers MR, Karvonen-Gutierrez CA (2010) The evolving role of obesity in knee osteoarthritis. Curr Opin Rheumatol 22(5):533\u2013537","journal-title":"Curr Opin Rheumatol"},{"key":"3816_CR9","doi-asserted-by":"crossref","first-page":"231","DOI":"10.1242\/dmm.001180","volume":"2","author":"PL Huang","year":"2009","unstructured":"Huang PL (2009) A comprehensive definition for metabolic syndrome. Dis Model Mech 2:231\u2013237","journal-title":"Dis Model Mech"},{"key":"3816_CR10","first-page":"S383","volume":"8","author":"G Singh","year":"2002","unstructured":"Singh G, Miller JD, Lee FH, Pettitt D, Russell MW (2002) Prevalence of cardiovascular disease risk factors among US adults with self-reported osteoarthritis: data from the third National Health and Nutrition Examination Survey. Am J Manag Care 8:S383\u2013S391","journal-title":"Am J Manag Care"},{"key":"3816_CR11","doi-asserted-by":"crossref","first-page":"9","DOI":"10.3810\/pgm.2009.11.2073","volume":"121","author":"RA Puenpatom","year":"2009","unstructured":"Puenpatom RA, Victor TW (2009) Increased prevalence of metabolic syndrome in individuals with osteoarthritis: an analysis of NHANES III data. Postgrad Med 121:9\u201320","journal-title":"Postgrad Med"},{"key":"3816_CR12","doi-asserted-by":"crossref","first-page":"168","DOI":"10.1016\/j.joca.2008.07.003","volume":"17","author":"G Engstrom","year":"2009","unstructured":"Engstrom G, Gerhardsson de Verdier M, Rollof J, Nilsson PM, Lohmander LS (2009) C-reactive protein, metabolic syndrome and incidence of severe hip and knee osteoarthritis. A population-based cohort study. Osteoarthr Cartil 17:168\u2013173","journal-title":"Osteoarthr Cartil"},{"key":"3816_CR13","first-page":"745","volume":"24","author":"AS Al-Arfaj","year":"2003","unstructured":"Al-Arfaj AS (2003) Radiographic osteoarthritis and serum cholesterol. Saudi Med J 24:745\u2013747","journal-title":"Saudi Med J"},{"key":"3816_CR14","doi-asserted-by":"crossref","first-page":"169","DOI":"10.1080\/030097401300162969","volume":"30","author":"T Sturmer","year":"2001","unstructured":"Sturmer T, Brenner H, Brenner RE, Gunther KP (2001) Non-insulin dependent diabetes mellitus (NIDDM) and patterns of osteoarthritis. The Ulm Osteoarthritis Study. Scand J Rheumatol 30:169\u2013171","journal-title":"Scand J Rheumatol"},{"key":"3816_CR15","doi-asserted-by":"publisher","unstructured":"Bija DM, Luma HN, Temfack E et al (2014) Patterns of knee osteoarthritis in a hospital setting in sub-Saharan Africa. Clin Rheumatol. \nhttps:\/\/doi.org\/10.1007\/s10067-014-2702-3","DOI":"10.1007\/s10067-014-2702-3"},{"key":"3816_CR16","doi-asserted-by":"crossref","first-page":"1039","DOI":"10.1002\/art.1780290816","volume":"29","author":"R Altman","year":"1986","unstructured":"Altman R, Asch E, Bloch D et al (1986) Development of criteria for the classification and reporting of osteoarthritis. Classification of osteoarthritis of the knee. Diagnostic and Therapeutic Criteria Committee of the American Rheumatism Association. Arthritis Rheum 29:1039\u20131049","journal-title":"Arthritis Rheum"},{"key":"3816_CR17","first-page":"5","volume":"5","author":"AO Akinpelu","year":"2011","unstructured":"Akinpelu AO, Alonge TO, Maduagwu SM, Odole AC (2011) Prevalence and pattern of osteoarthritis in North eastern Nigerian rural community. East Afr Orthop J 5:5\u201311","journal-title":"East Afr Orthop J"},{"key":"3816_CR18","unstructured":"Hassard TH (1991) Understanding biostatistics. Elsev Health Sci Yr book 167\u2013187"},{"key":"3816_CR19","doi-asserted-by":"crossref","first-page":"659","DOI":"10.1001\/jama.1949.02900430001001","volume":"140","author":"O Steinbrocker","year":"1949","unstructured":"Steinbrocker O, Traeger CH, Batterman RC (1949) Therapeutic criteria in rheumatoid arthritis. JAMA 140:659\u2013662","journal-title":"JAMA"},{"key":"3816_CR20","unstructured":"The IDF consensus worldwide definition of the metabolic syndrome. 2006. (\nhttp:\/\/www.idf.org\/webdata\/docs\/MetS_def_update2006.pdf\n\n) Accessed March 2007"},{"key":"3816_CR21","doi-asserted-by":"crossref","first-page":"494","DOI":"10.1136\/ard.16.4.494","volume":"16","author":"J Kellgren","year":"1957","unstructured":"Kellgren J, Lawrence J (1957) Radiologic assessment of osteoarthritis. Ann Rheum Dis 16:494\u2013501","journal-title":"Ann Rheum Dis"},{"issue":"1","key":"3816_CR22","doi-asserted-by":"crossref","first-page":"18","DOI":"10.7326\/0003-4819-109-1-18","volume":"109","author":"DT Felson","year":"1988","unstructured":"Felson DT, Anderson JJ, Naimark A, Walker AM, Meenan RF (1988) Obesity and knee osteoarthritis: the Framingham Study. Ann Intern Med 109(1):18\u201324","journal-title":"Ann Intern Med"},{"issue":"1","key":"3816_CR23","doi-asserted-by":"crossref","first-page":"179","DOI":"10.1093\/oxfordjournals.aje.a114939","volume":"128","author":"JJ Anderson","year":"1988","unstructured":"Anderson JJ, Felson DT (1988) Factors associated with osteoarthritis of the knee in the first national Health and Nutrition Examination Survey (NHANES I): evidence for an association with overweight, race, and physical demands of work. Am J Epidemiol 128(1):179\u2013189","journal-title":"Am J Epidemiol"},{"key":"3816_CR24","first-page":"8","volume":"2","author":"DA Ibrahim","year":"2014","unstructured":"Ibrahim DA, Borodo MM, Adelowo OO (2014) Clinical pattern of knee osteoarthritis in patients seen at rheumatology clinic of Aminu Kano Teaching Hospital, North-western Nigeria. Afr J Rheumatol 2:8\u201312","journal-title":"Afr J Rheumatol"},{"key":"3816_CR25","doi-asserted-by":"crossref","first-page":"729","DOI":"10.1038\/nrrheum.2012.135","volume":"8","author":"Q Zhuo","year":"2012","unstructured":"Zhuo Q, Yang W, Chen J, Wang Y (2012) Metabolic syndrome meets osteoarthritis. Nat Rev Rheumatol 8:729\u2013737","journal-title":"Nat Rev Rheumatol"},{"issue":"12","key":"3816_CR26","first-page":"743","volume":"53","author":"S Maddah","year":"2015","unstructured":"Maddah S, Mahdizadeh J (2015) Association of metabolic syndrome and its components with knee osteoarthritis. Acta Med Iran 53(12):743\u2013748","journal-title":"Acta Med Iran"},{"key":"3816_CR27","doi-asserted-by":"publisher","first-page":"1194","DOI":"10.1002\/art.40087","volume":"69","author":"J Niu","year":"2017","unstructured":"Niu J, Clancy M, Aliabadi P, Vasan R, Felson DT (2017) Metabolic syndrome, its components, and knee osteoarthritis: the Framingham Osteoarthritis Study. Arthritis Rheumatol 69:1194\u20131203. \nhttps:\/\/doi.org\/10.1002\/art.40087","journal-title":"Arthritis Rheumatol"},{"key":"3816_CR28","doi-asserted-by":"crossref","first-page":"38","DOI":"10.1186\/1741-7015-9-38","volume":"9","author":"A Lanas","year":"2011","unstructured":"Lanas A, Garcia-Tell G, Armada B, Oteo-Alvaro A (2011) Prescription patterns and appropriateness of NSAID therapy according to gastrointestinal risk and cardiovascular history in patients with diagnoses of osteoarthritis. BMC Med 9:38\u201344","journal-title":"BMC Med"},{"key":"3816_CR29","doi-asserted-by":"crossref","first-page":"336","DOI":"10.1002\/art.1780350313","volume":"35","author":"CA Horn","year":"1992","unstructured":"Horn CA, Bradley JD, Brandt KD, Kreipke DL, Smowman SD, Kalasinski LA (1992) Impairment of osteophyte formation in patients with type II diabetes mellitus and knee osteoarthritis. Arthritis Rheum 35:336\u2013334","journal-title":"Arthritis Rheum"},{"key":"3816_CR30","doi-asserted-by":"publisher","first-page":"e000077","DOI":"10.1136\/rmdopen-2015-000077","volume":"1","author":"K Louati","year":"2015","unstructured":"Louati K, Vidal C, Berenbaum F (2015) Association between diabetes mellitus and osteoarthritis: systematic literature review and meta-analysis. RMD Open 1:e000077. \nhttps:\/\/doi.org\/10.1136\/rmdopen-2015-000077","journal-title":"RMD Open"},{"issue":"8","key":"3816_CR31","first-page":"38","volume":"12","author":"A Ellabban","year":"2015","unstructured":"Ellabban A, Abdelhakeem M, Hamdy M, Nassr M, Fathy I (2015) Impact of obesity on activity and severity parameters of osteoarthritis. Life Sci J 12(8):38\u201344","journal-title":"Life Sci J"},{"key":"3816_CR32","doi-asserted-by":"crossref","first-page":"603","DOI":"10.1186\/1471-2458-13-603","volume":"13","author":"CD Han","year":"2013","unstructured":"Han CD, Yang IH, Lee WS, Park YJ, Park KK (2013) Correlation between metabolic syndrome and knee osteoarthritis: data from the Korean National Health and Nutrition Examination Survey (KNHANES). BMC Public Health 13:603","journal-title":"BMC Public Health"},{"issue":"7","key":"3816_CR33","doi-asserted-by":"crossref","first-page":"133","DOI":"10.21037\/atm.2016.03.48","volume":"4","author":"H Li","year":"2016","unstructured":"Li H, George DM, Jaarsma RL, Mao X (2016) Metabolic syndrome and components exacerbate osteoarthritis symptoms of pain, depression and reduced knee function. Ann Transl Med 4(7):133","journal-title":"Ann Transl Med"},{"key":"3816_CR34","doi-asserted-by":"crossref","first-page":"3177","DOI":"10.1210\/jc.2014-1043","volume":"99","author":"D Shin","year":"2014","unstructured":"Shin D (2014) Association between metabolic syndrome, radiographic knee osteoarthritis, and intensity of knee pain: results of a national survey. J Clin Endocrinol Metab 99:3177\u20133183","journal-title":"J Clin Endocrinol Metab"},{"key":"3816_CR35","doi-asserted-by":"publisher","first-page":"7242478","DOI":"10.1155\/2016\/7242478","volume":"2016","author":"H Wang","year":"2016","unstructured":"Wang H, Cheng Y, Shao D et al (2016) Metabolic syndrome increases the risk for knee osteoarthritis: a meta-analysis. Evid Based Complement Altern Med 2016:7242478. \nhttps:\/\/doi.org\/10.1155\/2016\/7242478","journal-title":"Evid Based Complement Altern Med"},{"key":"3816_CR36","doi-asserted-by":"crossref","first-page":"25","DOI":"10.1186\/2052-1847-5-25","volume":"5","author":"S Salih","year":"2013","unstructured":"Salih S, Sutton P (2013) Obesity, knee osteoarthritis and knee arthroplasty: a review. BMC Sports Sci, Med Rehabil 5:25","journal-title":"BMC Sports Sci, Med Rehabil"},{"key":"3816_CR37","doi-asserted-by":"crossref","first-page":"1328","DOI":"10.1002\/art.24739","volume":"61","author":"M Sowers","year":"2009","unstructured":"Sowers M, Karvonen-Gutierrez CA, Palmieri-Smith R, Jacobson JA, Jiang Y, Ashton Miller JA (2009) Knee osteoarthritis in obese women with cardiometabolic clustering. Arthritis Rheum 61:1328\u20131336","journal-title":"Arthritis Rheum"},{"key":"3816_CR38","doi-asserted-by":"crossref","first-page":"211","DOI":"10.1038\/sj.ijo.0803715","volume":"32","author":"A Anandacoomarasamy","year":"2008","unstructured":"Anandacoomarasamy A, Caterson I, Sambrook P, Fransen M, March L (2008) The impact of obesity on the musculoskeletal system. Int J Obes 32:211\u2013222","journal-title":"Int J Obes"},{"key":"3816_CR39","doi-asserted-by":"crossref","first-page":"198","DOI":"10.1177\/145749691210100310","volume":"101","author":"J J\u00e4rvenp\u00e4\u00e4","year":"2012","unstructured":"J\u00e4rvenp\u00e4\u00e4 J, Kettunen J, Soininvaara T, Miettinen H, Kr\u00f6ger H (2012) Obesity has a negative impact on clinical outcome after total knee arthroplasty. Scand J Surg 101:198\u2013203","journal-title":"Scand J Surg"},{"key":"3816_CR40","first-page":"226","volume":"41","author":"S Vasilic-Brasnjevic","year":"2016","unstructured":"Vasilic-Brasnjevic S, Marinkovic J, Vlajinac H, Vasiljevic N, Jakovljevic B, Nikic M, Maksimovic M (2016) Association of body mass index and waist circumference with severity of knee osteoarthritis. Acta Reumatol Port 41:226\u2013231","journal-title":"Acta Reumatol Port"}],"container-title":["Clinical Rheumatology"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/article\/10.1007\/s10067-017-3816-1\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s10067-017-3816-1.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s10067-017-3816-1.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2017,10,13]],"date-time":"2017-10-13T06:08:26Z","timestamp":1507874906000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/s10067-017-3816-1"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,9,13]]},"references-count":40,"journal-issue":{"issue":"11","published-print":{"date-parts":[[2017,11]]}},"alternative-id":["3816"],"URL":"https:\/\/doi.org\/10.1007\/s10067-017-3816-1","relation":{},"ISSN":["0770-3198","1434-9949"],"issn-type":[{"value":"0770-3198","type":"print"},{"value":"1434-9949","type":"electronic"}],"subject":[],"published":{"date-parts":[[2017,9,13]]}}}