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All participating subjects gave their informed consent in writing prior to participation in the study.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Approval and consent statement"}},{"value":"None of the authors have any conflict of interest regarding this manuscript. For the purposes of full transparency, we acknowledge the following disclosures. S.K. has served as a consultant for Crealta, Horizon, and Ironwood. B.S. serves on the Philips Volcano Medical Education Steering Committee and has a research grant from Siemens Medical Solutions. M.H.P. serves and\/or has served as a consultant for AstraZeneca, Crealta, Horizon, Ironwood, and SOBI, and has been an investigative site for a sponsored trial by Takeda.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of interest statement"}}]}}