{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,16]],"date-time":"2025-10-16T20:36:43Z","timestamp":1760647003185},"reference-count":42,"publisher":"Springer Science and Business Media LLC","issue":"8","license":[{"start":{"date-parts":[[2019,4,16]],"date-time":"2019-04-16T00:00:00Z","timestamp":1555372800000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Clin Rheumatol"],"published-print":{"date-parts":[[2019,8]]},"DOI":"10.1007\/s10067-019-04542-0","type":"journal-article","created":{"date-parts":[[2019,4,16]],"date-time":"2019-04-16T01:30:37Z","timestamp":1555378237000},"page":"2265-2273","update-policy":"http:\/\/dx.doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":13,"title":["Value of serum procalcitonin for the diagnosis of bacterial septic arthritis in daily practice in rheumatology"],"prefix":"10.1007","volume":"38","author":[{"given":"Micka\u00ebl","family":"Chouk","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Frank","family":"Verhoeven","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Maxime","family":"Sondag","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xavier","family":"Guillot","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Cl\u00e9ment","family":"Prati","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Daniel","family":"Wendling","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2019,4,16]]},"reference":[{"key":"4542_CR1","doi-asserted-by":"publisher","unstructured":"Sharff KA, Richards EP, Townes JM (2013) Clinical management of septic arthritis. Curr Rheumatol Rep 15:332. \n                              https:\/\/doi.org\/10.1007\/s11926-013-0332-4","DOI":"10.1007\/s11926-013-0332-4"},{"key":"4542_CR2","doi-asserted-by":"publisher","unstructured":"Ferrand J, El Samad Y, Brunschweiler B et al (2016) Morbimortality in adult patients with septic arthritis: a three-year hospital-based study. BMC Infect Dis 16:239. \n                              https:\/\/doi.org\/10.1186\/s12879-016-1540-0","DOI":"10.1186\/s12879-016-1540-0"},{"key":"4542_CR3","doi-asserted-by":"publisher","first-page":"1478","DOI":"10.1001\/jama.297.13.1478","volume":"297","author":"ME Margaretten","year":"2007","unstructured":"Margaretten ME, Kohlwes J, Moore D, Bent S (2007) Does this adult patient have septic arthritis? JAMA 297:1478\u20131488. \n                              https:\/\/doi.org\/10.1001\/jama.297.13.1478","journal-title":"JAMA"},{"key":"4542_CR4","doi-asserted-by":"publisher","unstructured":"Mathew AJ, Ravindran V (2014) Infections and arthritis. Best Pract Res Clin Rheumatol 28:935\u2013959. \n                              https:\/\/doi.org\/10.1016\/j.berh.2015.04.009","DOI":"10.1016\/j.berh.2015.04.009"},{"key":"4542_CR5","doi-asserted-by":"publisher","unstructured":"Kim H, Kim J, Ihm C (2010) The usefulness of multiplex PCR for the identification of bacteria in joint infection. J Clin Lab Anal 24:175\u2013181. \n                              https:\/\/doi.org\/10.1002\/jcla.20384","DOI":"10.1002\/jcla.20384"},{"key":"4542_CR6","doi-asserted-by":"publisher","first-page":"483","DOI":"10.1177\/000456320103800505","volume":"38","author":"J Whicher","year":"2001","unstructured":"Whicher J, Bienvenu J, Monneret G (2001) Procalcitonin as an acute phase marker. Ann Clin Biochem 38:483\u2013493. \n                              https:\/\/doi.org\/10.1177\/000456320103800505","journal-title":"Ann Clin Biochem"},{"issue":"Suppl 1","key":"4542_CR7","first-page":"S57","volume":"49","author":"P Maruna","year":"2000","unstructured":"Maruna P, Nedeln\u00edkov\u00e1 K, G\u00fcrlich R (2000) Physiology and genetics of procalcitonin. Physiol Res 49(Suppl 1):S57\u2013S61","journal-title":"Physiol Res"},{"key":"4542_CR8","doi-asserted-by":"publisher","first-page":"231","DOI":"10.1093\/rheumatology\/keu416","volume":"54","author":"MM Shaikh","year":"2015","unstructured":"Shaikh MM, Hermans LE, van Laar JM (2015) Is serum procalcitonin measurement a useful addition to a rheumatologist\u2019s repertoire? A review of its diagnostic role in systemic inflammatory diseases and joint infections. Rheumatol Oxf Engl 54:231\u2013240. \n                              https:\/\/doi.org\/10.1093\/rheumatology\/keu416","journal-title":"Rheumatol Oxf Engl"},{"key":"4542_CR9","doi-asserted-by":"publisher","first-page":"5578","DOI":"10.1210\/en.2003-0854","volume":"144","author":"P Linscheid","year":"2003","unstructured":"Linscheid P, Seboek D, Nylen ES, Langer I, Schlatter M, Becker KL, Keller U, M\u00fcller B (2003) In vitro and in vivo calcitonin I gene expression in parenchymal cells: a novel product of human adipose tissue. Endocrinology 144:5578\u20135584. \n                              https:\/\/doi.org\/10.1210\/en.2003-0854","journal-title":"Endocrinology"},{"key":"4542_CR10","doi-asserted-by":"publisher","first-page":"79","DOI":"10.1097\/00003643-200102000-00004","volume":"18","author":"M Meisner","year":"2001","unstructured":"Meisner M, Lohs T, Huettemann E, Schmidt J, Hueller M, Reinhart K (2001) The plasma elimination rate and urinary secretion of procalcitonin in patients with normal and impaired renal function. Eur J Anaesthesiol 18:79\u201387","journal-title":"Eur J Anaesthesiol"},{"key":"4542_CR11","doi-asserted-by":"publisher","first-page":"1166","DOI":"10.1016\/j.ajem.2017.06.014","volume":"35","author":"J Zhao","year":"2017","unstructured":"Zhao J, Zhang S, Zhang L, Dong X, Li J, Wang Y, Yao Y (2017) Serum procalcitonin levels as a diagnostic marker for septic arthritis: a meta-analysis. Am J Emerg Med 35:1166\u20131171. \n                              https:\/\/doi.org\/10.1016\/j.ajem.2017.06.014","journal-title":"Am J Emerg Med"},{"key":"4542_CR12","doi-asserted-by":"publisher","first-page":"895","DOI":"10.1002\/art.1780200320","volume":"20","author":"SL Wallace","year":"1977","unstructured":"Wallace SL, Robinson H, Masi AT, Decker JL, Mccarty DJ, Y\u00fc T\u2019F (1977) Preliminary criteria for the classification of the acute arthritis of primary gout. Arthritis Rheum 20:895\u2013900","journal-title":"Arthritis Rheum"},{"key":"4542_CR13","doi-asserted-by":"publisher","first-page":"563","DOI":"10.1136\/ard.2010.139105","volume":"70","author":"W Zhang","year":"2011","unstructured":"Zhang W, Doherty M, Bardin T, Barskova V, Guerne PA, Jansen TL, Leeb BF, Perez-Ruiz F, Pimentao J, Punzi L, Richette P, Sivera F, Uhlig T, Watt I, Pascual E (2011) European League Against Rheumatism recommendations for calcium pyrophosphate deposition. Part I: terminology and diagnosis. Ann Rheum Dis 70:563\u2013570. \n                              https:\/\/doi.org\/10.1136\/ard.2010.139105","journal-title":"Ann Rheum Dis"},{"key":"4542_CR14","doi-asserted-by":"publisher","first-page":"770","DOI":"10.1136\/ard.2009.108217","volume":"68","author":"M Rudwaleit","year":"2009","unstructured":"Rudwaleit M, Landew\u00e9 R, van der Heijde D et al (2009) The development of Assessment of SpondyloArthritis international Society classification criteria for axial spondyloarthritis (part I): classification of paper patients by expert opinion including uncertainty appraisal. Ann Rheum Dis 68:770\u2013776. \n                              https:\/\/doi.org\/10.1136\/ard.2009.108217","journal-title":"Ann Rheum Dis"},{"key":"4542_CR15","doi-asserted-by":"publisher","first-page":"25","DOI":"10.1136\/ard.2010.133645","volume":"70","author":"M Rudwaleit","year":"2011","unstructured":"Rudwaleit M, van der Heijde D, Landew\u00e9 R et al (2011) The Assessment of SpondyloArthritis International Society classification criteria for peripheral spondyloarthritis and for spondyloarthritis in general. Ann Rheum Dis 70:25\u201331. \n                              https:\/\/doi.org\/10.1136\/ard.2010.133645","journal-title":"Ann Rheum Dis"},{"key":"4542_CR16","doi-asserted-by":"publisher","first-page":"1580","DOI":"10.1136\/ard.2010.138461","volume":"69","author":"D Aletaha","year":"2010","unstructured":"Aletaha D, Neogi T, Silman AJ, Funovits J, Felson DT, Bingham CO, Birnbaum NS, Burmester GR, Bykerk VP, Cohen MD, Combe B, Costenbader KH, Dougados M, Emery P, Ferraccioli G, Hazes JM, Hobbs K, Huizinga TW, Kavanaugh A, Kay J, Kvien TK, Laing T, Mease P, Menard HA, Moreland LW, Naden RL, Pincus T, Smolen JS, Stanislawska-Biernat E, Symmons D, Tak PP, Upchurch KS, Vencovsky J, Wolfe F, Hawker G (2010) 2010 rheumatoid arthritis classification criteria: an American College of Rheumatology\/European League Against Rheumatism collaborative initiative. Ann Rheum Dis 69:1580\u20131588. \n                              https:\/\/doi.org\/10.1136\/ard.2010.138461","journal-title":"Ann Rheum Dis"},{"key":"4542_CR17","doi-asserted-by":"publisher","first-page":"198","DOI":"10.1136\/ard.35.3.198","volume":"35","author":"JH Newman","year":"1976","unstructured":"Newman JH (1976) Review of septic arthritis throughout the antibiotic era. Ann Rheum Dis 35:198\u2013205","journal-title":"Ann Rheum Dis"},{"key":"4542_CR18","doi-asserted-by":"publisher","first-page":"807","DOI":"10.1007\/s10096-012-1812-6","volume":"32","author":"C-J Shen","year":"2013","unstructured":"Shen C-J, Wu M-S, Lin K-H, Lin WL, Chen HC, Wu JY, Lee MCH, Lee CC (2013) The use of procalcitonin in the diagnosis of bone and joint infection: a systemic review and meta-analysis. Eur J Clin Microbiol Infect Dis Off Publ Eur Soc Clin Microbiol 32:807\u2013814. \n                              https:\/\/doi.org\/10.1007\/s10096-012-1812-6","journal-title":"Eur J Clin Microbiol Infect Dis Off Publ Eur Soc Clin Microbiol"},{"key":"4542_CR19","doi-asserted-by":"publisher","unstructured":"Paosong S, Narongroeknawin P, Pakchotanon R et al (2015) Serum procalcitonin as a diagnostic aid in patients with acute bacterial septic arthritis. Int J Rheum Dis 18:352\u2013359. \n                              https:\/\/doi.org\/10.1111\/1756-185X.12496","DOI":"10.1111\/1756-185X.12496"},{"key":"4542_CR20","first-page":"123","volume":"24","author":"CA Scir\u00e8","year":"2006","unstructured":"Scir\u00e8 CA, Cavagna L, Perotti C, Bruschi E, Caporali R, Montecucco C (2006) Diagnostic value of procalcitonin measurement in febrile patients with systemic autoimmune diseases. Clin Exp Rheumatol 24:123\u2013128","journal-title":"Clin Exp Rheumatol"},{"key":"4542_CR21","doi-asserted-by":"publisher","first-page":"1074","DOI":"10.1136\/ard.2008.098335","volume":"68","author":"D-Y Chen","year":"2009","unstructured":"Chen D-Y, Chen Y-M, Ho W-L, Chen HH, Shen GH, Lan JL (2009) Diagnostic value of procalcitonin for differentiation between bacterial infection and non-infectious inflammation in febrile patients with active adult-onset Still\u2019s disease. Ann Rheum Dis 68:1074\u20131075. \n                              https:\/\/doi.org\/10.1136\/ard.2008.098335","journal-title":"Ann Rheum Dis"},{"key":"4542_CR22","doi-asserted-by":"publisher","first-page":"274","DOI":"10.1007\/BF02962246","volume":"26","author":"V Schwenger","year":"1998","unstructured":"Schwenger V, Sis J, Breitbart A, Andrassy K (1998) CRP levels in autoimmune disease can be specified by measurement of procalcitonin. Infection 26:274\u2013276","journal-title":"Infection"},{"key":"4542_CR23","first-page":"1531","volume":"25","author":"F Moosig","year":"1998","unstructured":"Moosig F, Csernok E, Reinhold-Keller E, Schmitt W, Gross WL (1998) Elevated procalcitonin levels in active Wegener\u2019s granulomatosis. J Rheumatol 25:1531\u20131533","journal-title":"J Rheumatol"},{"issue":"Suppl 6","key":"4542_CR24","first-page":"839","volume":"59","author":"K Zycinska","year":"2008","unstructured":"Zycinska K, Wardyn KA, Zielonka TM et al (2008) Procalcitonin as an indicator of systemic response to infection in active pulmonary Wegener\u2019s granulomacytosis. J Physiol Pharmacol Off J Pol Physiol Soc 59(Suppl 6):839\u2013844","journal-title":"J Physiol Pharmacol Off J Pol Physiol Soc"},{"key":"4542_CR25","doi-asserted-by":"crossref","unstructured":"Okada Y, Minakami H, Tomomasa T et al (2004) Serum procalcitonin concentration in patients with Kawasaki disease. J Infect 48:199\u2013205","DOI":"10.1016\/j.jinf.2003.08.002"},{"key":"4542_CR26","doi-asserted-by":"publisher","first-page":"71","DOI":"10.2174\/1874312901409010071","volume":"9","author":"K Herrmann","year":"2015","unstructured":"Herrmann K, Schinke S, Csernok E, Moosig F, Holle JU (2015) Diagnostic value of procalcitonin in ANCA-associated vasculitis (AAV) to differentiate between disease activity, infection and drug hypersensitivity. Open Rheumatol J 9:71\u201376. \n                              https:\/\/doi.org\/10.2174\/1874312901409010071","journal-title":"Open Rheumatol J"},{"key":"4542_CR27","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0132855","volume":"10","author":"W Liu","year":"2015","unstructured":"Liu W, Sigdel KR, Wang Y, Su Q, Huang Y, Zhang YL, Chen J, Duan L, Shi G (2015) High level serum procalcitonin associated gouty arthritis susceptibility: from a southern Chinese Han population. PLoS One 10:e0132855. \n                              https:\/\/doi.org\/10.1371\/journal.pone.0132855","journal-title":"PLoS One"},{"key":"4542_CR28","doi-asserted-by":"publisher","first-page":"1471","DOI":"10.1007\/s10096-009-0807-4","volume":"28","author":"O Steichen","year":"2009","unstructured":"Steichen O, Bouvard E, Grateau G, Bailleul S, Capeau J, Lef\u00e8vre G (2009) Diagnostic value of procalcitonin in acutely hospitalized elderly patients. Eur J Clin Microbiol Infect Dis Off Publ Eur Soc Clin Microbiol 28:1471\u20131476. \n                              https:\/\/doi.org\/10.1007\/s10096-009-0807-4","journal-title":"Eur J Clin Microbiol Infect Dis Off Publ Eur Soc Clin Microbiol"},{"key":"4542_CR29","doi-asserted-by":"publisher","first-page":"393","DOI":"10.1197\/j.aem.2003.10.027","volume":"11","author":"JM Caterino","year":"2004","unstructured":"Caterino JM, Scheatzle MD, Forbes ML, D\u2019Antonio JA (2004) Bacteremic elder emergency department patients: procalcitonin and white count. Acad Emerg Med Off J Soc Acad Emerg Med 11:393\u2013396","journal-title":"Acad Emerg Med Off J Soc Acad Emerg Med"},{"key":"4542_CR30","doi-asserted-by":"publisher","unstructured":"Zhang H, Wang X, Zhang Q, Xia Y, Liu D (2017) Comparison of procalcitonin and high-sensitivity C-reactive protein for the diagnosis of sepsis and septic shock in the oldest old patients. BMC Geriatr 17:173. \n                              https:\/\/doi.org\/10.1186\/s12877-017-0566-5","DOI":"10.1186\/s12877-017-0566-5"},{"key":"4542_CR31","first-page":"2556","volume":"95","author":"J Zhang","year":"2015","unstructured":"Zhang J, Liu J, Long L, Zhou Q, Cheng J, Zhou B (2015) Value of procalcitonin measurement in the diagnosis of bacterial infections in patients with fever and flare of chronic gouty arthritis. Zhonghua Yi Xue Za Zhi 95:2556\u20132559","journal-title":"Zhonghua Yi Xue Za Zhi"},{"key":"4542_CR32","doi-asserted-by":"publisher","first-page":"1139","DOI":"10.3349\/ymj.2016.57.5.1139","volume":"57","author":"ST Choi","year":"2016","unstructured":"Choi ST, Song JS (2016) Serum procalcitonin as a useful serologic marker for differential diagnosis between acute gouty attack and bacterial infection. Yonsei Med J 57:1139\u20131144. \n                              https:\/\/doi.org\/10.3349\/ymj.2016.57.5.1139","journal-title":"Yonsei Med J"},{"key":"4542_CR33","doi-asserted-by":"publisher","first-page":"218","DOI":"10.1111\/j.0105-2896.2009.00860.x","volume":"233","author":"F Martinon","year":"2010","unstructured":"Martinon F (2010) Mechanisms of uric acid crystal-mediated autoinflammation. Immunol Rev 233:218\u2013232. \n                              https:\/\/doi.org\/10.1111\/j.0105-2896.2009.00860.x","journal-title":"Immunol Rev"},{"key":"4542_CR34","doi-asserted-by":"publisher","first-page":"1090","DOI":"10.1093\/rheumatology\/keh640","volume":"44","author":"N Dalbeth","year":"2005","unstructured":"Dalbeth N, Haskard DO (2005) Mechanisms of inflammation in gout. Rheumatol Oxf Engl 44:1090\u20131096. \n                              https:\/\/doi.org\/10.1093\/rheumatology\/keh640","journal-title":"Rheumatol Oxf Engl"},{"key":"4542_CR35","doi-asserted-by":"publisher","first-page":"1512","DOI":"10.1210\/jc.2002-021444","volume":"89","author":"KL Becker","year":"2004","unstructured":"Becker KL, Nyl\u00e9n ES, White JC, M\u00fcller B, Snider RH Jr (2004) Clinical review 167: procalcitonin and the calcitonin gene family of peptides in inflammation, infection, and sepsis: a journey from calcitonin back to its precursors. J Clin Endocrinol Metab 89:1512\u20131525. \n                              https:\/\/doi.org\/10.1210\/jc.2002-021444","journal-title":"J Clin Endocrinol Metab"},{"key":"4542_CR36","doi-asserted-by":"publisher","first-page":"1040","DOI":"10.1097\/00003246-200004000-00021","volume":"28","author":"C Kettelhack","year":"2000","unstructured":"Kettelhack C, Hohenberger P, Schulze G, Kilpert B, Schlag PM (2000) Induction of systemic serum procalcitonin and cardiocirculatory reactions after isolated limb perfusion with recombinant human tumor necrosis factor-alpha and melphalan. Crit Care Med 28:1040\u20131046","journal-title":"Crit Care Med"},{"key":"4542_CR37","doi-asserted-by":"publisher","first-page":"319","DOI":"10.1007\/s00296-012-2363-y","volume":"33","author":"M Talebi-Taher","year":"2013","unstructured":"Talebi-Taher M, Shirani F, Nikanjam N, Shekarabi M (2013) Septic versus inflammatory arthritis: discriminating the ability of serum inflammatory markers. Rheumatol Int 33:319\u2013324. \n                              https:\/\/doi.org\/10.1007\/s00296-012-2363-y","journal-title":"Rheumatol Int"},{"key":"4542_CR38","doi-asserted-by":"publisher","first-page":"238","DOI":"10.1016\/j.jbspin.2007.07.012","volume":"75","author":"G Streit","year":"2008","unstructured":"Streit G, Alber D, Toubin MM, Toussirot E, Wendling D (2008) Procalcitonin, C-reactive protein, and complement-3a assays in synovial fluid for diagnosing septic arthritis: preliminary results. Jt Bone Spine Rev Rhum 75:238\u2013239. \n                              https:\/\/doi.org\/10.1016\/j.jbspin.2007.07.012","journal-title":"Jt Bone Spine Rev Rhum"},{"key":"4542_CR39","doi-asserted-by":"publisher","first-page":"845","DOI":"10.1007\/s15010-013-0467-2","volume":"41","author":"K Saeed","year":"2013","unstructured":"Saeed K, Dryden M, Sitjar A, White G (2013) Measuring synovial fluid procalcitonin levels in distinguishing cases of septic arthritis, including prosthetic joints, from other causes of arthritis and aseptic loosening. Infection 41:845\u2013849. \n                              https:\/\/doi.org\/10.1007\/s15010-013-0467-2","journal-title":"Infection"},{"key":"4542_CR40","doi-asserted-by":"publisher","first-page":"1075","DOI":"10.3892\/etm.2014.1870","volume":"8","author":"C Wang","year":"2014","unstructured":"Wang C, Zhong DA, Liao Q et al (2014) Procalcitonin levels in fresh serum and fresh synovial fluid for the differential diagnosis of knee septic arthritis from rheumatoid arthritis, osteoarthritis and gouty arthritis. Exp Ther Med 8:1075\u20131080. \n                              https:\/\/doi.org\/10.3892\/etm.2014.1870","journal-title":"Exp Ther Med"},{"key":"4542_CR41","first-page":"303","volume":"23","author":"M Martinot","year":"2005","unstructured":"Martinot M, Sordet C, Soubrier M, Pu\u00e9chal X, Saraux A, Liot\u00e9 F, Guggenbuhl P, L\u00e8gre V, Jaulhac B, Maillefert JF, Zeisel M, Coumaros G, Sibilia J (2005) Diagnostic value of serum and synovial procalcitonin in acute arthritis: a prospective study of 42 patients. Clin Exp Rheumatol 23:303\u2013310","journal-title":"Clin Exp Rheumatol"},{"key":"4542_CR42","unstructured":"Christ-Crain M, M\u00fcller B (2005) Procalcitonin in bacterial infections--hype, hope, more or less? Swiss Med Wkly 135:451\u2013460. \n                              https:\/\/doi.org\/2005\/31\/smw-11169"}],"container-title":["Clinical Rheumatology"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s10067-019-04542-0.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1007\/s10067-019-04542-0\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s10067-019-04542-0.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,4,14]],"date-time":"2020-04-14T23:22:06Z","timestamp":1586906526000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/s10067-019-04542-0"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,4,16]]},"references-count":42,"journal-issue":{"issue":"8","published-print":{"date-parts":[[2019,8]]}},"alternative-id":["4542"],"URL":"https:\/\/doi.org\/10.1007\/s10067-019-04542-0","relation":{},"ISSN":["0770-3198","1434-9949"],"issn-type":[{"value":"0770-3198","type":"print"},{"value":"1434-9949","type":"electronic"}],"subject":[],"published":{"date-parts":[[2019,4,16]]},"assertion":[{"value":"12 January 2019","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"25 March 2019","order":2,"name":"revised","label":"Revised","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"1 April 2019","order":3,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"16 April 2019","order":4,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"Since PCT evaluation is a regular procedure in front of sepsis in emergency room, no specific ethical procedure was required. Nevertheless, informed consent was obtained from each patient.","order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Compliance with ethical standards"}},{"value":"None.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Disclosures"}}]}}