{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,24]],"date-time":"2026-10-24T21:04:53Z","timestamp":1792875893297,"version":"4.5.0"},"reference-count":39,"publisher":"Springer Science and Business Media LLC","issue":"6","license":[{"start":{"date-parts":[[2020,2,8]],"date-time":"2020-02-08T00:00:00Z","timestamp":1581120000000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"},{"start":{"date-parts":[[2020,2,8]],"date-time":"2020-02-08T00:00:00Z","timestamp":1581120000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Clin Rheumatol"],"published-print":{"date-parts":[[2020,6]]},"DOI":"10.1007\/s10067-020-04937-4","type":"journal-article","created":{"date-parts":[[2020,2,8]],"date-time":"2020-02-08T09:02:24Z","timestamp":1581152544000},"page":"1783-1792","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":63,"title":["Benefits of exercise in patients with rheumatoid arthritis: a randomized controlled trial of a patient-specific exercise programme"],"prefix":"10.1007","volume":"39","author":[{"given":"Maha","family":"Azeez","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ciara","family":"Clancy","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tom","family":"O\u2019Dwyer","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Conor","family":"Lahiff","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fiona","family":"Wilson","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gaye","family":"Cunnane","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2020,2,8]]},"reference":[{"key":"4937_CR1","doi-asserted-by":"publisher","first-page":"659","DOI":"10.1016\/j.mayocp.2012.03.011","volume":"87","author":"JM Davis 3rd","year":"2012","unstructured":"Davis JM 3rd, Matteson EL, American College of R, European League Against R (2012) My treatment approach to rheumatoid arthritis. Mayo Clin Proc 87:659\u2013673","journal-title":"Mayo Clin Proc"},{"key":"4937_CR2","doi-asserted-by":"publisher","first-page":"1094","DOI":"10.1016\/S0140-6736(10)60826-4","volume":"376","author":"DL Scott","year":"2010","unstructured":"Scott DL, Wolfe F, Huizinga TW (2010) Rheumatoid arthritis. Lancet 376:1094\u20131108","journal-title":"Lancet"},{"key":"4937_CR3","doi-asserted-by":"publisher","first-page":"123","DOI":"10.1016\/j.autrev.2011.09.001","volume":"11","author":"M Prete","year":"2011","unstructured":"Prete M, Racanelli V, Digiglio L, Vacca A, Dammacco F, Perosa F (2011) Extra-articular manifestations of rheumatoid arthritis: an update. Autoimmun Rev 11:123\u2013131","journal-title":"Autoimmun Rev"},{"key":"4937_CR4","doi-asserted-by":"publisher","first-page":"1090","DOI":"10.1002\/art.23935","volume":"59","author":"Z Nadareishvili","year":"2008","unstructured":"Nadareishvili Z, Michaud K, Hallenbeck JM, Wolfe F (2008) Cardiovascular, rheumatologic, and pharmacologic predictors of stroke in patients with rheumatoid arthritis: a nested, case-control study. Arthritis Rheum 59:1090\u20131096","journal-title":"Arthritis Rheum"},{"key":"4937_CR5","doi-asserted-by":"publisher","first-page":"2737","DOI":"10.1002\/1529-0131(200112)44:12<2737::AID-ART460>3.0.CO;2-#","volume":"44","author":"ID del Rincon","year":"2001","unstructured":"del Rincon ID, Williams K, Stern MP, Freeman GL, Escalante A (2001) High incidence of cardiovascular events in a rheumatoid arthritis cohort not explained by traditional cardiac risk factors. Arthritis Rheum 44:2737\u20132745","journal-title":"Arthritis Rheum"},{"key":"4937_CR6","doi-asserted-by":"publisher","first-page":"62","DOI":"10.1002\/acr.21810","volume":"65","author":"PP Katz","year":"2013","unstructured":"Katz PP, Yazdany J, Trupin L, Schmajuk G, Margaretten M, Barton J, Criswell LA, Yelin EH (2013) Sex differences in assessment of obesity in rheumatoid arthritis. Arthritis Care Res 65:62\u201370","journal-title":"Arthritis Care Res"},{"key":"4937_CR7","doi-asserted-by":"publisher","first-page":"1819","DOI":"10.1136\/annrheumdis-2012-202075","volume":"72","author":"A Stavropoulos-Kalinoglou","year":"2013","unstructured":"Stavropoulos-Kalinoglou A, Metsios GS, Veldhuijzen van Zanten JJ, Nightingale P, Kitas GD, Koutedakis Y (2013) Individualised aerobic and resistance exercise training improves cardiorespiratory fitness and reduces cardiovascular risk in patients with rheumatoid arthritis. Ann Rheum Dis 72:1819\u20131825","journal-title":"Ann Rheum Dis"},{"key":"4937_CR8","doi-asserted-by":"publisher","first-page":"623","DOI":"10.1007\/s10067-010-1584-2","volume":"30","author":"B Strasser","year":"2011","unstructured":"Strasser B, Leeb G, Strehblow C, Schobersberger W, Haber P, Cauza E (2011) The effects of strength and endurance training in patients with rheumatoid arthritis. Clin Rheumatol 30:623\u2013632","journal-title":"Clin Rheumatol"},{"key":"4937_CR9","doi-asserted-by":"publisher","first-page":"681640","DOI":"10.4061\/2011\/681640","volume":"2011","author":"JK Cooney","year":"2011","unstructured":"Cooney JK, Law RJ, Matschke V et al (2011) Benefits of exercise in rheumatoid arthritis. J Aging Res 2011:681640","journal-title":"J Aging Res"},{"key":"4937_CR10","doi-asserted-by":"publisher","first-page":"42","DOI":"10.1002\/art.23255","volume":"59","author":"T Sokka","year":"2008","unstructured":"Sokka T, Hakkinen A, Kautiainen H et al (2008) Physical inactivity in patients with rheumatoid arthritis: data from twenty-one countries in a cross-sectional, international study. Arthritis Rheum 59:42\u201350","journal-title":"Arthritis Rheum"},{"key":"4937_CR11","doi-asserted-by":"publisher","first-page":"339","DOI":"10.1358\/mf.2004.26.5.831324","volume":"26","author":"S Appenzeller","year":"2004","unstructured":"Appenzeller S, Bertolo MB, Costallat LT (2004) Cognitive impairment in rheumatoid arthritis. Methods Find Exp Clin Pharmacol 26:339\u2013343","journal-title":"Methods Find Exp Clin Pharmacol"},{"key":"4937_CR12","doi-asserted-by":"publisher","first-page":"239","DOI":"10.1097\/PSY.0b013e3181d14633","volume":"72","author":"PJ Smith","year":"2010","unstructured":"Smith PJ, Blumenthal JA, Hoffman BM, Cooper H, Strauman TA, Welsh-Bohmer K, Browndyke JN, Sherwood A (2010) Aerobic exercise and neurocognitive performance: a meta-analytic review of randomized controlled trials. Psychosom Med 72:239\u2013252","journal-title":"Psychosom Med"},{"key":"4937_CR13","doi-asserted-by":"publisher","first-page":"876","DOI":"10.4065\/mcp.2011.0252","volume":"86","author":"JE Ahlskog","year":"2011","unstructured":"Ahlskog JE, Geda YE, Graff-Radford NR, Petersen RC (2011) Physical exercise as a preventive or disease-modifying treatment of dementia and brain aging. Mayo Clin Proc 86:876\u2013884","journal-title":"Mayo Clin Proc"},{"key":"4937_CR14","unstructured":"Urbaniak GC, Plous S (2013) Research Randomizer (Version 4.0)"},{"key":"4937_CR15","doi-asserted-by":"publisher","first-page":"524","DOI":"10.1097\/00005768-199704000-00015","volume":"29","author":"C Nunez","year":"1997","unstructured":"Nunez C, Gallagher D, Visser M, Pi-Sunyer FX, Wang Z, Heymsfield SB (1997) Bioimpedance analysis: evaluation of leg-to-leg system based on pressure contact footpad electrodes. Med Sci Sports Exerc 29:524\u2013531","journal-title":"Med Sci Sports Exerc"},{"key":"4937_CR16","doi-asserted-by":"publisher","first-page":"38","DOI":"10.1002\/art.1780380106","volume":"38","author":"JS Smolen","year":"1995","unstructured":"Smolen JS, Breedveld FC, Eberl G, Jones I, Leeming M, Wylie GL, Kirkpatrick J (1995) Validity and reliability of the twenty-eight-joint count for the assessment of rheumatoid arthritis activity. Arthritis Rheum 38:38\u201343","journal-title":"Arthritis Rheum"},{"key":"4937_CR17","doi-asserted-by":"publisher","first-page":"3113","DOI":"10.1002\/art.22130","volume":"54","author":"T Sokka","year":"2006","unstructured":"Sokka T, Kautiainen H, Hannonen P, Pincus T (2006) Changes in health assessment questionnaire disability scores over five years in patients with rheumatoid arthritis compared with the general population. Arthritis Rheum 54:3113\u20133118","journal-title":"Arthritis Rheum"},{"key":"4937_CR18","doi-asserted-by":"publisher","first-page":"93","DOI":"10.1097\/00006199-199303000-00006","volume":"42","author":"BL Belza","year":"1993","unstructured":"Belza BL, Henke CJ, Yelin EH, Epstein WV, Gilliss CL (1993) Correlates of fatigue in older adults with rheumatoid arthritis. Nurs Res 42:93\u201399","journal-title":"Nurs Res"},{"key":"4937_CR19","doi-asserted-by":"publisher","first-page":"451","DOI":"10.1590\/S0482-50042011000500005","volume":"51","author":"GS Novaes","year":"2011","unstructured":"Novaes GS, Perez MO, Beraldo MB, Pinto CR, Gianini RJ (2011) Correlation of fatigue with pain and disability in rheumatoid arthritis and osteoarthritis, respectively. Rev Bras Reumatol 51:451\u2013455","journal-title":"Rev Bras Reumatol"},{"key":"4937_CR20","first-page":"321","volume":"51","author":"RT Schmidt","year":"1970","unstructured":"Schmidt RT, Toews JV (1970) Grip strength as measured by the Jamar dynamometer. Arch Phys Med Rehabil 51:321\u2013327","journal-title":"Arch Phys Med Rehabil"},{"key":"4937_CR21","first-page":"323","volume":"3","author":"RA Bruce","year":"1971","unstructured":"Bruce RA (1971) Exercise testing of patients with coronary heart disease. Principles and normal standards for evaluation. Ann Clin Res 3:323\u2013332","journal-title":"Ann Clin Res"},{"key":"4937_CR22","doi-asserted-by":"publisher","first-page":"546","DOI":"10.1016\/0002-8703(73)90502-4","volume":"85","author":"RA Bruce","year":"1973","unstructured":"Bruce RA, Kusumi F, Hosmer D (1973) Maximal oxygen intake and nomographic assessment of functional aerobic impairment in cardiovascular disease. Am Heart J 85:546\u2013562","journal-title":"Am Heart J"},{"key":"4937_CR23","first-page":"307","volume":"35","author":"MJ Karvonen","year":"1957","unstructured":"Karvonen MJ, Kentala E, Mustala O (1957) The effects of training on heart rate; a longitudinal study. Ann Med Exp Biol Fenn 35:307\u2013315","journal-title":"Ann Med Exp Biol Fenn"},{"key":"4937_CR24","unstructured":"Heyward V (2010) Advanced fitness assessment and exercise prescription, 6th edn. Human Kinetics"},{"key":"4937_CR25","doi-asserted-by":"publisher","first-page":"695","DOI":"10.1111\/j.1532-5415.2005.53221.x","volume":"53","author":"ZS Nasreddine","year":"2005","unstructured":"Nasreddine ZS, Phillips NA, Bedirian V et al (2005) The Montreal cognitive Assessment, MoCA: a brief screening tool for mild cognitive impairment. J Am Geriatr Soc 53:695\u2013699","journal-title":"J Am Geriatr Soc"},{"key":"4937_CR26","doi-asserted-by":"publisher","first-page":"1435","DOI":"10.1249\/mss.0b013e3180616aa2","volume":"39","author":"ME Nelson","year":"2007","unstructured":"Nelson ME, Rejeski WJ, Blair SN, Duncan PW, Judge JO, King AC, Macera CA, Castaneda-Sceppa C (2007) Physical activity and public health in older adults: recommendation from the American College of Sports Medicine and the American Heart Association. Med Sci Sports Exerc 39:1435\u20131445","journal-title":"Med Sci Sports Exerc"},{"key":"4937_CR27","doi-asserted-by":"publisher","first-page":"515","DOI":"10.1002\/1529-0131(200103)44:3<515::AID-ANR98>3.0.CO;2-5","volume":"44","author":"A Hakkinen","year":"2001","unstructured":"Hakkinen A, Sokka T, Kotaniemi A, Hannonen P (2001) A randomized two-year study of the effects of dynamic strength training on muscle strength, disease activity, functional capacity, and bone mineral density in early rheumatoid arthritis. Arthritis Rheum 44:515\u2013522","journal-title":"Arthritis Rheum"},{"key":"4937_CR28","doi-asserted-by":"publisher","first-page":"615","DOI":"10.1136\/ard.59.8.615","volume":"59","author":"CH van den Ende","year":"2000","unstructured":"van den Ende CH, Breedveld FC, le Cessie S, Dijkmans BA, de Mug AW, Hazes JM (2000) Effect of intensive exercise on patients with active rheumatoid arthritis: a randomised clinical trial. Ann Rheum Dis 59:615\u2013621","journal-title":"Ann Rheum Dis"},{"key":"4937_CR29","doi-asserted-by":"publisher","first-page":"1869","DOI":"10.1161\/01.ATV.0000036611.77940.F8","volume":"22","author":"TS Church","year":"2002","unstructured":"Church TS, Barlow CE, Earnest CP, Kampert JB, Priest EL, Blair SN (2002) Associations between cardiorespiratory fitness and C-reactive protein in men. Arterioscler Thromb Vasc Biol 22:1869\u20131876","journal-title":"Arterioscler Thromb Vasc Biol"},{"key":"4937_CR30","doi-asserted-by":"publisher","first-page":"163","DOI":"10.1016\/j.atherosclerosis.2013.09.006","volume":"231","author":"DF van Breukelen-van der Stoep","year":"2013","unstructured":"van Breukelen-van der Stoep DF, Klop B, van Zeben D, Hazes JM, Castro CM (2013) Cardiovascular risk in rheumatoid arthritis: how to lower the risk? Atherosclerosis 231:163\u2013172","journal-title":"Atherosclerosis"},{"key":"4937_CR31","doi-asserted-by":"publisher","first-page":"617","DOI":"10.1111\/j.1365-2648.2006.04054.x","volume":"56","author":"J Neill","year":"2006","unstructured":"Neill J, Belan I, Ried K (2006) Effectiveness of non-pharmacological interventions for fatigue in adults with multiple sclerosis, rheumatoid arthritis, or systemic lupus erythematosus: a systematic review. J Adv Nurs 56:617\u2013635","journal-title":"J Adv Nurs"},{"key":"4937_CR32","doi-asserted-by":"publisher","first-page":"1966","DOI":"10.3899\/jrheum.131282","volume":"41","author":"L Durcan","year":"2014","unstructured":"Durcan L, Wilson F, Cunnane G (2014) The effect of exercise on sleep and fatigue in rheumatoid arthritis: a randomized controlled study. J Rheumatol 41:1966\u20131973","journal-title":"J Rheumatol"},{"key":"4937_CR33","first-page":"505","volume":"23","author":"A Hakkinen","year":"2005","unstructured":"Hakkinen A, Pakarinen A, Hannonen P et al (2005) Effects of prolonged combined strength and endurance training on physical fitness, body composition and serum hormones in women with rheumatoid arthritis and in healthy controls. Clin Exp Rheumatol 23:505\u2013512","journal-title":"Clin Exp Rheumatol"},{"issue":"4","key":"4937_CR34","doi-asserted-by":"publisher","first-page":"279","DOI":"10.3109\/03009742.2013.858769","volume":"43","author":"T Uutela","year":"2014","unstructured":"Uutela T, Kautiainen H, Jarvenpaa S, Salomaa S, Hakala M, Hakkinen A (2014) Waist circumference based abdominal obesity may be helpful as a marker for unmet needs in patients with RA. Scand J Rheumatol:43, 279\u2013285","journal-title":"Scandinavian Journal of Rheumatology"},{"key":"4937_CR35","doi-asserted-by":"publisher","first-page":"1547","DOI":"10.1001\/jama.282.16.1547","volume":"282","author":"M Wei","year":"1999","unstructured":"Wei M, Kampert JB, Barlow CE, Nichaman MZ, Gibbons LW, Paffenbarger RS Jr, Blair SN (1999) Relationship between low cardiorespiratory fitness and mortality in normal-weight, overweight, and obese men. JAMA 282:1547\u20131553","journal-title":"JAMA"},{"key":"4937_CR36","doi-asserted-by":"publisher","first-page":"521","DOI":"10.1093\/rheumatology\/38.6.521","volume":"38","author":"A Fraser","year":"1999","unstructured":"Fraser A, Vallow J, Preston A, Cooper RG (1999 Please note theat reference sblah and blajh have the same bib details. Please delete the duplicated reference and renumber the affected ref citations) Predicting 'normal' grip strength for rheumatoid arthritis patients. Rheumatology 38:521\u2013528","journal-title":"Rheumatology"},{"key":"4937_CR37","doi-asserted-by":"publisher","first-page":"33","DOI":"10.1002\/1529-0131(199902)12:1<33::AID-ART6>3.0.CO;2-4","volume":"12","author":"B Dellhag","year":"1999","unstructured":"Dellhag B, Bjelle A (1999) A five-year followup of hand function and activities of daily living in rheumatoid arthritis patients. Arthritis Care Res 12:33\u201341","journal-title":"Arthritis Care Res"},{"key":"4937_CR38","first-page":"S85","volume":"23","author":"T Pincus","year":"2005","unstructured":"Pincus T (2005) Rheumatology function tests: quantitative physical measures to monitor morbidity and predict mortality in patients with rheumatic diseases. Clin Exp Rheumatol 23:S85\u2013S89","journal-title":"Clin Exp Rheumatol"},{"key":"4937_CR39","doi-asserted-by":"publisher","first-page":"280","DOI":"10.1007\/s12160-008-9064-5","volume":"36","author":"AL Smiley-Oyen","year":"2008","unstructured":"Smiley-Oyen AL, Lowry KA, Francois SJ, Kohut ML, Ekkekakis P (2008) Exercise, fitness, and neurocognitive function in older adults: the \"selective improvement\" and \"cardiovascular fitness\" hypotheses. Ann Behav Med 36:280\u2013291","journal-title":"Ann Behav Med"}],"container-title":["Clinical Rheumatology"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s10067-020-04937-4.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1007\/s10067-020-04937-4\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s10067-020-04937-4.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,2,8]],"date-time":"2021-02-08T21:58:34Z","timestamp":1612821514000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/s10067-020-04937-4"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,2,8]]},"references-count":39,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2020,6]]}},"alternative-id":["4937"],"URL":"https:\/\/doi.org\/10.1007\/s10067-020-04937-4","relation":{},"ISSN":["0770-3198","1434-9949"],"issn-type":[{"value":"0770-3198","type":"print"},{"value":"1434-9949","type":"electronic"}],"subject":[],"published":{"date-parts":[[2020,2,8]]},"assertion":[{"value":"13 November 2019","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"1 January 2020","order":2,"name":"revised","label":"Revised","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"10 January 2020","order":3,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"8 February 2020","order":4,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Compliance with ethical standards"}},{"value":"None.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Disclosures"}}]}}