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Patients who had a rheumatologist confirmed diagnosis of AS and nr-axSpA were eligible to participate. Patient demographics, symptoms, and medication use were reported by the rheumatologist, while work disability and QoL measures were reported by the patient. Patient demographics, symptoms, QoL and treatment patterns of AS and nr-axSpA patients were compared using parametric tests and non-parametric tests when appropriate.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Results<\/jats:title>\n                <jats:p>A total of 515 AS patients and 495 nr-axSpA patients were included in this analysis. A higher proportion of AS patients were male (<jats:italic>p<\/jats:italic> &lt; 0.001), older (<jats:italic>p<\/jats:italic> = 0.014), and more likely to be prescribed a biologic (<jats:italic>p<\/jats:italic> &lt; 0.0001). On average, AS patients experienced slightly more symptoms at diagnosis (<jats:italic>p<\/jats:italic> = 0.023); however, nr-axSpA patients were more likely to experience enthesitis (<jats:italic>p<\/jats:italic> = 0.048) and synovitis (<jats:italic>p<\/jats:italic> = 0.003). Patient reported outcomes such as the ASAS Health Index (<jats:italic>p<\/jats:italic> = 0.171), ASQoL (<jats:italic>p<\/jats:italic> = 0.296), BASDAI (<jats:italic>p<\/jats:italic> = 0.124), and WPAI (<jats:italic>p<\/jats:italic> = 0.183) were similar between AS and nr-axSpA patients after adjusting for confounding variables such as medication use.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Conclusions<\/jats:title>\n                <jats:p>AS and nr-axSpA patients share the same clinical features. The burden of the disease, as assessed by QoL measurements, is also similar in AS and nr-axSpA patients; however, despite these similarities, patients with nr-axSpA are less likely to be treated with a biologic.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>\n                           <jats:bold>Key Points<\/jats:bold>\n                        <\/jats:title>\n                <jats:p><jats:table-wrap><jats:table><jats:tbody>\n                      <jats:tr>\n                        <jats:td colspan=\"2\"><jats:italic>\u2022 Ankylosing spondylitis and non<\/jats:italic><jats:italic>\u2022 radiographic axial spondyloarthritis patients share similar clinical features and burden of disease.<\/jats:italic><jats:italic>\u2022 Quality of life is similar among ankylosing spondylitis and non<\/jats:italic><jats:italic>\u2022 radiographic axial spondyloarthritis after adjusting for current treatment patterns.<\/jats:italic><\/jats:td>\n                      <\/jats:tr>\n                    <\/jats:tbody><\/jats:table><\/jats:table-wrap><\/jats:p>\n              <\/jats:sec>","DOI":"10.1007\/s10067-021-05642-6","type":"journal-article","created":{"date-parts":[[2021,2,20]],"date-time":"2021-02-20T18:15:24Z","timestamp":1613844924000},"page":"3161-3167","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":21,"title":["Comparing symptoms, treatment patterns, and quality of life of ankylosing spondylitis and non-radiographic axial spondyloarthritis patients in the USA: findings from a patient and rheumatologist Survey"],"prefix":"10.1007","volume":"40","author":[{"given":"Theresa","family":"Hunter","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"David","family":"Sandoval","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nicola","family":"Booth","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Elizabeth","family":"Holdsworth","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Atul","family":"Deodhar","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2021,2,20]]},"reference":[{"key":"5642_CR1","doi-asserted-by":"publisher","first-page":"73","DOI":"10.1016\/S0140-6736(16)31591-4","volume":"390","author":"J Sieper","year":"2017","unstructured":"Sieper J, Poddubnyy D (2017) Axial spondyloarthritis. 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EH and NB are employees of Adelphi Real World. AD has received grants or research support from AbbVie, Eli Lilly, GlaxoSmithKline, Janssen, Novartis, Pfizer, and UCB Pharma and consulting fees from Eli Lilly, Janssen, Novartis, Pfizer, and UCB Pharma.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of interest"}}]}}